Claudio Verdugo

Claudio Verdugo
Universidad Austral de Chile · Facultad de Ciencias Veterinarias

MV PhD

About

52
Publications
10,343
Reads
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674
Citations
Introduction
Claudio Verdugo currently works in the Universidad Austral de Chile. Claudio does research in Molecular Epidemiology of Infectious Diseases and Ecology of Infectious Diseases.
Additional affiliations
May 2013 - present
Universidad Austral de Chile
Position
  • Professor (Associate)

Publications

Publications (52)
Article
Full-text available
We identified 3 novel and distinct avulaviruses were identified from Gentoo penguins sampled in Antarctica. We isolated these viruses and sequenced their complete genomes; serologic assays demonstrated that the viruses do not have cross-reactivity between them. Our findings suggest that these 3 new viruses represent members of 3 novel avulavirus sp...
Article
Full-text available
We have a limited understanding of the genetic and molecular basis of evolutionary changes in the size and proportion of limbs. We studied wing and pectoral skeleton reduction leading to flightlessness in the Galapagos cormorant ( Phalacrocorax harrisi). We sequenced and de novo assembled the genomes of four cormorant species and applied a predicti...
Article
Full-text available
In 2018, the order Mononegavirales was expanded by inclusion of 1 new genus and 12 novel species. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV) and summarizes additional taxonomic proposals that may affect the order in the near future.
Article
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We identified two RNA (paramyxovirus and coronavirus) and two DNA (adenovirus and herpesvirus) viruses in a common aquatic bird, the Neotropic Cormorant ( Phalacrocorax brasilianus), and determined their phylogenetic relationships to other global circulating variants. We analyzed 104 cloacal swabs from individuals collected at locations in Central...
Preprint
Full-text available
Effective interventions are mandatory to control the transmission and spread of SARS-CoV-2, a highly contagious virus causing devastating effects worldwide. Cost-effective approaches are pivotal tools required to increase the detection rates and escalate further in massive surveillance programs, especially in countries with limited resources that m...
Preprint
The main objective of this study was to estimate the performance, under local epidemiological conditions, of two in-house ELISA assays for the combined detection of anti-SARS-CoV-2 IgA, IgM, and IgG immunoglobulins. A total of 94 serum samples were used for the assessment, where 44 corresponded to sera collected before the pandemic (free SARS-CoV-2...
Preprint
Background: A series of abiotic and biotic modifications occur in an anthropogenic landscape which influence the ecology and physiology of wild hosts and their parasites. How these changes affect the parasitism is highly context-dependent, based on the host-parasite system and the type of perturbation. We aimed to investigate the differences in inf...
Article
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Porcine Astrovirus (PoAstV) causes mild diarrhea in young pigs and is considered an emerging virus in the swine industry worldwide. PoAstV has high genetic diversity and has been classified into five genetic lineages, PoAstV1-5. In Chile, only human astroviruses have been reported. This study aimed to determine the presence and genetic diversity of...
Article
Full-text available
Understanding the diversity and circulation dynamics of seasonal influenza viruses is key to public health decision-making. The limited genetic information of pre-pandemic seasonal IAVs in Chile has made it difficult to accurately reconstruct the phylogenetic relationships of these viruses within the country. The objective of this study was to dete...
Article
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High-performance–validated tests are essential for successful epidemiological monitoring, surveillance of parasitic infections, and comparative studies in wildlife populations. The Mini-FLOTAC is a novel flotation–based technique for the sensitive detection and quantification of gastrointestinal parasites that is recently being explored for use in...
Article
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In total, 57 ticks were collected from six white-tailed deer (Odocoileus virginianus) and three mule deer (O. hemionus) in northern Mexico during the 2017, 2018 and 2019 hunting seasons. Morphological features of adult male and female ticks were observed and photographed using a stereo-microscope and scanning electron micrography. The ticks were id...
Article
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The genetic diversity of populations is the basis for individual fitness and potential adaptability to environmental changes. The South American fur seal (Arctocephalus australis) is a pinniped species that is widely distributed along the southern cone of South America. However, two distinct populations have evolved: the Northern Pacific/Peruvian p...
Preprint
Full-text available
High-performance validated tests are essential for successful epidemiological monitoring, surveillance of parasitic infections, and comparative studies in wildlife populations. The Mini-FLOTAC is a novel flotation-based technique for the sensitive detection and quantification of gastrointestinal parasites that is recently being explored for use in...
Article
Large amounts of antibiotics from different sources have been released into coastal environments, especially in high human-populated areas, but comprehensive studies of antibiotic footprint in wildlife are scarce. Here we assess occurrence of antibiotic resistant bacteria (ARB) and antibiotic resistance gene (ARG) both in sediments and gut microbio...
Preprint
Full-text available
Understanding the diversity and circulation dynamics of seasonal influenza viruses is key to public health decision-making. The limited genetic information of pre-pandemic seasonal IAVs in Chile has made it difficult to accurately reconstruct the phylogenetic relationships of these viruses within the country. The objective of this study was to dete...
Article
Full-text available
We report the mitochondrial genome sequences of two migratory shorebirds, the Hudsonian godwit (Limosa haemastica) and the Red knot (Calidris canutus) obtained through shotgun sequencing. The mitogenome is of 16.445 bp for the godwit and 15.609 bp for the knot containing thirteen protein-coding genes, two rRNAs, twenty-two tRNAs, and a control regi...
Article
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Invasive Alien Species (IAS) threaten biodiversity, ecosystem functions and services, modify landscapes and impose costs to national economies. Management efforts are underway globally to reduce these impacts, but little attention has been paid to optimising the use of the scarce available resources when IAS are impossible to eradicate, and therefo...
Article
Migratory species often spend the non-breeding season in areas that differ in both distance from the breeding grounds and habitat quality, which can cause a segregation of the population. In sexually dimorphic species, differential energetic requirements and foraging strategies of each sex can lead to the use of different non-breeding grounds. Howe...
Article
Background: Point sources such as wastewater treatment plants (WWTPs) commonly discharge their effluent into rivers. Their waste may include antibiotic residues, disinfectants, antibiotic resistant bacteria (ARB), and Antimicrobial Resistance Genes (ARG). There is evidence that ARG can be found in the natural environment, but attribution to specif...
Article
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Human presence at intertidal areas could impact coastal biodiversity, including migratory waterbird species and the ecosystem services they provide. Assessing this impact is therefore essential to develop management measures compatible with migratory processes and associated biodiversity. Here, we assess the effects of human presence on the foragin...
Article
Neotropic cormorant (Phalacrocorax brasilianus) is a monomorphic species widely distributed along the American Continent. We used a rapid and efficient molecular technique centred on the chromo-helicase-DNA-binding gene in order to differentiate male and female sex chromosomes based on the size of introns. Males presented a Z chromosome with a sing...
Article
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Cystic echinococcosis (CE) is a zoonotic parasitic disease associated with Echinococcus granulosus. The parasite is maintained by domestic and wild canids as definitive hosts with several ungulate species as intermediate hosts in domestic and peridomestic transmission cycles. In Chile, CE is endemic, and the role of livestock and dogs ( Canis lupus...
Article
Full-text available
Hemosporidian parasites rarely infect aquatic birds. Few studies have been conducted in South America identifying some lineages of the genera Plasmodium, Leucocytozoon, and Haemoproteus, but none has been done in the Neotropic cormorant (Phalacrocorax brasilianus). This species is widely distributed through the American continent, from Southern USA...
Article
Full-text available
Although mites of the Orthohalarachne genus are common parasites of otariids, their role as agents of disease and in causing population-level mortality is unknown. In the austral summer of 2016, there was an increase in mortality among South American fur seal ( Arctocephalus australis) pups at Guafo Island, Northern Chilean Patagonia. Pups found de...
Article
Full-text available
1. South American fur seals, Arctocephalus australis, were intensively hunted for centuries, leaving the species at the edge of extinction. After the cessation of commercial hunting in the 20th century the overall population has increased to an estimated population of 250 000–300 000 individuals, with Guafo Island being the largest breeding colony...
Article
Full-text available
The complete mitochondrial DNA sequence of the South America fur seal (Arctocephalus australis) was obtained by a shotgun sequencing approach. The mitogenome is 16,372 bp in length and includes the genes coding for the two rRNA species (12S and 16S), 13 protein-coding genes, 22 transfer RNA genes, and a control region. The base composition is 33.0%...
Presentation
Genetic diversity of neotropic cormorant Phalacrocorax brasilianus in Chile
Article
Full-text available
We report a case of a Lady Amherst’s pheasant (Chrysolophus amherstiae) with diffuse granulomatous lesions in liver, spleen and intestine. Using histopathological and molecular diagnosis we detected Mycobacterium avium subsp. avium, etiological agent of avian tuberculosis. Further studies are needed to understand the role of wild birds in the persi...
Data
Methods and additional results in a study of avulaviruses in penguins in Antarctica.
Article
Lyme borreliosis is a vector-borne zoonosis caused by Borrelia burgdorferi sensu lato species complex spirochetes, which are maintained in transmission cycles among vertebrates and Ixodes ticks. Recently, a new genospecies within this complex, Borrelia chilensis, was described in Ixodes stilesi collected from the environment and from rodents in Chi...
Article
The advances of molecular techniques have increased the development of cost and time-effective libraries of molecular markers, such as microsatellites, which allow us to estimate genetic parameters in order to characterise species' population structures. The Neotropic Cormorant (Phalacrocorax brasilianus) is one of the most abundant and widespread...
Preprint
Full-text available
Changes in the size and proportion of limbs and other structures have played a key role in the adaptive evolution of species. However, despite the ubiquity of these modifications, we have a very limited idea of how these changes occur on the genetic and molecular levels. To fill this gap, we studied a recent and extreme case of wing and pectoral sk...
Article
Full-text available
Mange, a prevalent disease of dogs in Chile, is also a serious threat to wildlife. We report a case of sarcoptic mange in a South American gray fox or chilla fox ( Lycalopex griseus ). Further research is needed to understand the impact of mange in wildlife populations.
Article
Full-text available
A meta-analysis approach was used to extract the frequency of avian seropositivity to West Nile Virus (WNV) (fS) and mortality from WNV (fM) from the literature published between the years 2001-2010. The indices, fS and fM, were used to represent states of resistance (seropositivity with no or limited mortality) and susceptibility in birds (detecti...
Preprint
Full-text available
A meta-analysis approach was used to extract the frequency of avian seropositivity to West Nile Virus (WNV) ( f S) and mortality from WNV ( f M) from the literature published between the years 2001-2010. The indices, f S and f M, were used to represent states of resistance (seropositivity with no or limited mortality) and susceptibility in birds (d...
Article
The complete sequence of the Neotropic cormorant (Phalacrocorax brasilianus) mitochondrial DNA was obtained by the shotgun sequencing approach. The mitogenome is 19 042 bp in length and includes 13 protein-coding genes, 2 ribosomal subunit genes, 22 transfer RNA genes, a control region and a duplicated region of 2418 bp. The base composition is 32....
Article
Full-text available
Abstract We performed postmortem examination on four South American sea lions (Otaria byronia) from an urban colony in Valdivia, Chile. Chronic leptospirosis and suspected morbillivirus-like infection were diagnosed in one individual. Antibodies against Toxoplasma gondii and the zoonotic helminthes Contracaecum sp., Pseudoterranova sp., and Diphyll...
Article
Recent advances in high throughput molecular techniques have allowed the development of cost- and time-effective libraries of molecular markers, such as microsatellites, for population genetic studies in non-model species. The American crow, Corvus brachyrhynchos, is recognized to be one of the species that has been most negatively affected by the...
Article
Direct colloid osmometry provides an objective assessment of the oncotic effects of crystalloid or colloidal fluid therapy, which is especially useful in monitoring fluid therapy of critically ill camelids due to their tendency toward nonspecific hypoproteinemia with increased risk of developing edema and ascites. The aims of this study were to mea...
Article
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Island–continent isolation scenarios have played major roles in the understanding and development of evolutionary theories. During the last glacial maximum (LGM) in southern Chile, ice sheet advances and retreats formed the Patagonian archipelago along the southern Pacific Ocean. Chiloé Island is the largest island from the archipelago isolated fro...
Article
Full-text available
A 12-year-old adult, intact male puma (Puma concolor araucana) was evaluated because of abnormal hind limb gait and paresis. Neurological examination revealed a progressive paraparesis, bilateral pelvic limb proprioceptive deficit and tail paralysis. Survey radiographs and computed tomography (CT) were taken at the lumbosacral region in order to de...
Article
Full-text available
Un ejemplar de puma (Puma concolor araucana) macho intacto, adulto (12 años), fue evaluado debido a una paraparesis y deambulación anormal de los miembros pélvicos. Al examen neurológico se determinó una paraparesia progresiva, ataxia simétrica de los miembros pélvicos y parálisis de la cola. Se obtuvieron radiografías simples y una tomografía comp...
Article
Full-text available
Torpor is the physiologically controlled reduction of metabolic rate and body temperature experienced by small birds and mammals when facing periods of low temperature and/or food shortage. In this study, we provide a first quantitative description of torpor in the relict marsupial Dromiciops gliroides by: (1) characterizing body temperature (T B)...
Article
Full-text available
We assessed the importance of potential Sources of mortality for the Vulnerable southern pudu Pudu puda in southern Chile using the clinical records of wildlife rehabilitation centres, necropsies of animals found in the field and a review of the diet of potential predators. To assess whether the identified mortality sources operate in nominally pro...
Article
Full-text available
Avian bioenergetic studies suggest that, compared with other vertebrates, birds are efficient thermoregulators. However, most avian physiological studies have been performed in species of small body masses (less than 1 kg). In contrast to what might be anticipated, thermoregulatory abilities of large, flying birds are scarcely studied, especially i...
Article
Full-text available
Living organisms are continuously faced with several forms of environmental perturbation, one of the most important being human activity. In this scenario, the role of physiological studies on wildlife has proved to be important given that in vivo physiological variables reflect a great deal how sensitive animals are to acute environmental changes....
Article
Full-text available
The application of clinical biochemical techniques to determine the products of intermediary metabolism has proved to be a reliable approach for the study of the physiological state of animals in nature. More specifically, the determination of plasma metabolites, such as glucose, total proteins (PRO), albumin (ALB), globulins (GL), urea, uric acid,...

Projects

Projects (4)
Project
This ambitious, international project aims to preserve biodiversity, ecosystem services and livelihoods by improving the strategic, long-term management of damaging invasive non-native species (INNS) that cannot be eradicated and must be managed in perpetuity. The project levers existing high quality ecological data on animal and plant invasive species already acquired by LATAM project members, together with targeted new data collection (including from experimental control), and integrates this with state-of-the-art modelling approaches developed by the UK project members in order to deliver novel tools and approaches that can inform the effective management of INNS in the region.
Project
To explore whether there is a higher biodiversity and interactions of bacterial communities in tick species infecting mammal hosts at the wildlife/domestic interface than those at wild or peri urban areas and how mammals can contribute to the spread of these pathogens.