Claudine Domoney

• Chelsea and Westminster Hospital NHS Foundation Trust

Objectives To describe the attitudes and perceptions of postmenopausal women from the United Kingdom regarding menopause, vulvo-vaginal atrophy and its therapeutic management. Study design Post hoc analysis of the United Kingdom population from the REVIVE-EU Study. Main outcome measures The survey contained questions about women’s knowledge of me...

Objective: We describe cases of invasive group A Streptococcus (iGAS) in mothers or neonates and assess management according to national guidelines, which recommend administering antibiotics to both mother and neonate if either develops iGAS infection within 28 days of birth and investigation of clusters in maternity units. Design: Cross-section...

Consultations in the gynaecology clinic should seek to understand the patient's problem and the effect on their quality of life and physical and psychological health. All unexpected symptoms may be expressed in various ways, often not corresponding with the doctor's categorisation. Frequently psychosexual disorders are therefore not addressed. Unde...

As a result of advanced treatment techniques, great strides have been made in the enhancement of survival in patients with pelvic malignancies. However, the control and even cure of these malignancies come with a price; and all health professionals involved in the care of these patients must be aware of issues of post-treatment sexual dysfunction a...

Since the Women's Health Initiative report of 2002, there has been reluctance to provide women with hormone replacement therapy due to a lack of clarity about the potential risks. This book reviews all aspects of the menopause and places the benefits and risks of hormone therapy into perspective. It fully informs the reader regarding the evidence b...

Vaginal or vulvovaginal atrophy is a widespread but poorly recognized condition of peri- and post-menopausal women. It causes urogenital symptoms of dryness, reduced lubrication, itching, burning, irritable bladder symptoms and painful intercourse. This impacts quality of life and sexual health, but increases with time rather than reduces, as with...

Women with sexual problems commonly present in gynaecology clinics. They require both a physical and psychological approach to their management due to the combination of mind and body involvement in sexual activity. The skills involved in psychosexual medicine can be practised by all gynaecologists as they use the consultation and examination to re...

Abstract Female sexual dysfunction (FSD) is multidimensional with a complex interplay of biopsychosocial factors modulating the clinical expression of sexual symptoms and associated distress. During the entire reproductive lifespan, intra- and interpersonal experiences shape human neuroendocrine and neurovascular sexual pathways. These are dependen...

To understand the physical and emotional impact of postmenopausal vaginal discomfort on relationships between women and their male partners. In a quantitative, Internet-based survey, 8200 individuals from the UK, Denmark, Sweden, Norway, Finland, France, Italy, US and Canada (postmenopausal, married/cohabiting women, aged 55-65 years, who had exper...

Introduction and hypothesis: The objective of this study was to create a valid, reliable, and responsive sexual function measure in women with pelvic floor disorders (PFDs) for both sexually active (SA) and inactive (NSA) women. Methods: Expert review identified concept gaps and generated items evaluated with cognitive interviews. Women underwen...

Introduction: This paper provides a detailed discussion of the psychometric analysis and scoring of a revised measure of sexual function in women with pelvic floor disorders (PFD): the Pelvic Organ Prolapse Incontinence Sexual Questionnaire, IUGA-Revised (PISQ-IR). Methods: Standard tools for evaluating item distributions, relationships, and psy...

Thirteen million women aged over 45, live in the UK (1%). This number is increasing. This has implications for short-term symptom control of the menopause and long-term health issues, and for the number of new referrals to clinic. To determine the pattern of referrals to the specialist menopause clinic, to see if referrals fit the criteria for refe...

Sexual assault is common and may present in all areas of obstetrics and gynaecology. All staff need to be aware of the key issues in assessment and treatment of such women and the local arrangements for forensic examination, where appropriate, in addition to the legal framework. These women deserve informed, sensitive physical and psychological car...

A recent Journal article1 had the same effect on these readers as the mention of bodywork did at the workshop on vaginismus and sexual pain: a palpable shiver! However we recognise these feelings for what they are: discomfort, ignorance and fear. A casual glance at the article could lead to a misinterpretation that bodywork is a recognised part of...

Female sexual dysfunction is highly prevalent and often a common response to the reproductive changes that occur throughout a woman's life. Sexual problems and associated distress are often seen in gynaecology clinics. Therefore an understanding of the normal female sexual response cycle, the classification of sexual dysfunction, the management of...

With population ageing, service expansion in urogynaecology is a necessity. The aim of this study was to determine the feasibility of a nurse specialist-led triage clinic as a novel way of outpatient care provision. Review of the patient pathway through the service over a 15-month period demonstrated effective patient management with timely order o...

Heterotopic pregnancy is a well-established complication of assisted reproductive technology. We report a case of intrauterine pregnancy combined with abdominal pregnancy diagnosed at 12 weeks in a 37-year-old nulliparous woman. Following surgical resection of the ectopic, implantation of hemorrhagic ectopic trophoblastic tissue onto bowel serosa,...

To evaluate the effect on climacteric symptoms and quality of life, and the safety of four doses of progestelle progesterone cream administered for 24 weeks to postmenopausal women complaining of moderate to severe menopausal symptoms. Design Single-centre, double-blind, randomized, placebo-controlled study. Population Two hundred and twenty-three...

Sexual function in women has often been measured by clinicians using parameters which appear easier to assess (frequency and pain). Therefore, the range of normality is often broad and of limited value when investigating population groups. The most important features to explore are satisfaction and/or distress with sexual activity. Although female...

It has been established that the lower urinary tract is sensitive to the effects of estrogen, sharing a common embryological origin with the female genital tract, the urogenital sinus. Urge urinary incontinence is more prevalent after the menopause, and the peak prevalence of stress incontinence occurs around the time of the menopause. Many studies...

Many older females frequently present with lower urinary tract symptoms resulting from recurrent infections or urogenital atrophy. Many factors contribute to the development of recurrent urinary tract infections (UTIs) in older women and lack of oestrogen should be seen as an independent risk factor. Topical oestrogen therapy returns the urogenital...

Premenstrual syndrome is a collection of symptoms that may be encountered by up to 95% of the population, although it is estimated to affect 5% of women severely. The use of complementary and alternative therapies is high among this group, but does not seem to compromise conventional treatment. It has been established that complementary therapies a...

To assess long-term hormone replacement therapy (HRT) usage in women after hysterectomy and to assess the relationship between age and long-term use of HRT in these women. Problems and comments of those women responding to a questionnaire were evaluated. A postal semistructured questionnaire survey was performed in a single gynecological practice....

In this study, we investigate the use of complementary therapies by women attending a specialist premenstrual syndrome (PMS) clinic in the UK. Data was collected via an anonymous questionnaire survey of 100 women attending the clinic. Results showed 91% of women had used at least one form of complementary therapy for the management of their premens...

To assess the usage of both conventional and complementary therapies by peri- and postmenopausal women for the treatment of menopausal symptoms. A prospective questionnaire was completed by 200 consecutive patients attending a tertiary referral London-based specialist menopause clinic between September and December 1999. The median age of responder...

Leptin is a metabolic regulator of the hypothalamic- pituitary-gonadal axis, and plays an important role in human reproduction. Its neuro-endocrine effects are mediated by interactions with receptors in the hypothalamus, where emotional drive is also controlled. We postulated that circulating leptin concentrations are increased in premenstrual synd...