Claudia Delgadillo Puga

• Dra.
• Investigador en Ciencias Médicas D at National Institute of Medical Sciences and Nutrition Salvador Zubirán

Four ruminally cannulated crossbred sheep (25+/-3.4kg BW) were divided into a 4x4 Latin square design to measure the effects of controlled-release urea supplement (CRUS). The basal diet consisted of 60% sugar cane tops (Saccharum officinarum), 30% full plant corn stubble (Zea mays), and 10% King grass (Pennisetum purpureum). Feed intake, digestibil...

Four cannulated sheep were used to study ruminal fermentation of a diet consisting of 60% sugar cane tops (Saccharum officinarum), 30% corn stubble (Zea mays), 10% King grass (Pennisetum purpureum) and 0% (control), 10, 20 or 30% controlled-release urea supplement (CRUS) (diets 1, 2, 3 and 4, respectively). Average ruminal pH did not differ among d...

Recent attention has been given to animal feeding and its impact on human nutrition. Animal feeding is essential for meeting human dietary needs, making it a subject of significant interest and investigation. This review seeks to outline the current understanding of this disciplinary area, with a focus on key research areas and their potential impl...

Hola!! Amigos les comparto esta entrevista. deseando que alimente su información. Abrazos Ya está disponible la entrevista transmitida a través de UAM Radio 94.1 en entrevista la Dra. Claudia Delgadillo Puga investigadora del Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" abordando el tema: Biotransformación y beneficios a l...

El Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Curso de Verano Bioquímica y Fisiología 2023. En apoyo a la Investigación Registrate en https://nutrinnovacion.com/ Sesiones grabadas en alta resolución y sesiones en vivo por Zoom

Pecans (Carya illinoinensis) are considered a functional food due to the high content of polyunsaturated fatty acids, dietary fiber and polyphenols. To determine the effect of whole pecans (WP) or a pecan polyphenol (PP) extract on the development of metabolic abnormalities in mice fed a high-fat (HF) diet, we fed C57BL/6 mice with a Control diet (...

Obesity causes systemic inflammation, hepatic and renal damage, as well as gut microbiota dysbiosis. Alternative vegetable sources rich in polyphenols are known to prevent or delay the progression of metabolic abnormalities during obesity. Vachellia farnesiana (VF) is a potent source of polyphenols with antioxidant and anti-inflammatory activities...

Cardamom seed (Elettaria cardamomum (L.) Maton; EC) is consumed in several countries worldwide and is considered a nutraceutical spice since it exerts antioxidant, anti-inflammatory, and metabolic activities. In obese individuals, EC intake also favors weight loss. However, the mechanism for these effects has not been studied. Here, we identified t...

Translational research. Phase 1 clinical trial. healthy volunteers Mexico. INCMNSZ. Polyphenolic beverage-Vachellia farnesiana.

Summer Course. Metabolic Biochemistry 2022. In support of research. INCMNSZ https://nutrinnovacion.com/ platform is the videos for you to watch at the time you like and at the end of the day, there will be a live Q&A session with the professor. The second week is live sessions and includes question and answer time. All sessions are recorded for yo...

Translational research. The consumption of ultra-processed foods, with a high content of carbohydrates, and without fiber, increases the risk of obesity and Type 2 Diabetes Mellitus (DM2); Faced with this problem, currently, the therapeutic and prevention target for these anomalies has focused on managing and reducing the rate of absorption and met...

Simple Summary The aim of this study was to review the benefits of producing milk and cheese under grazing/browsing systems on rangelands in terms of bioactivity and the health benefits of their consumption in these animals. Firstly, we looked over at the forages consumed by goats on the rangelands and at the plant’s bioactive compounds. Additional...

Alternativas dietarias para mitigar las alteraciones metabólicas de la obesidad, a partir de los frutos de Acacia farnesiana en ratones machos C57BL/6.

In order to determine whether organic production may be a viable option for goat farmers of the lower Mixteca region of Puebla, Mexico, in order to increase sustainability of their farms, we evaluated the extent to which these goat farms fulfill organic standards. Additionally, we revised their level of sustainability by calculating an Organic Live...

Owing to their antioxidant properties, caffeoylquinic acid (CQA)-derivatives could potentially improve the impaired metabolism in hepatic cells, however, their effect on mitochondrial function has not been demonstrated yet. Here, we evaluated the impact of three CQA-derivatives extracted from purple sweet potato, namely 5-CQA, 3,4- and 4,5-diCQA, o...

Goat’s milk is a rich source of bioactive compounds (peptides, conjugated linoleic acid, short chain fatty acids, monounsaturated and polyunsaturated fatty acids, polyphenols such as phytoestrogens and minerals among others) that exert important health benefits. However, goat’s milk composition depends on the type of food provided to the animal and...

Ellagic acid (EA) is a component of ellagitannins, present in crops such as pecans, walnuts, and many berries, which metabolized by the gut microbiota forms urolithins A, B, C, or D. In this study, ellagic acid, as well as urolithins A and B, were tested on 3T3-L1 preadipocytes for differentiation and lipid accumulation. In addition, inflammation w...

Ellagic acid (EA) is a component of ellagitannins, present in crops such as pecans, walnuts, and many berries, which metabolized by the gut microbiota forms urolithins A, B, C, or D. In this study, ellagic acid, as well as urolithins A and B, were tested on 3T3-L1 preadipocytes for differentiation and lipid accumulation. In addition, inflammation w...

Simple Summary This paper updates the knowledge on the effects of grazing ruminants on milk quality and cheese with emphasis on unsaturated fatty acids, volatile compounds antioxidant protection degree and phenols. It focuses on the effects of the forage species and its phenological phase on the fatty acid (FA) profile of the forage and the milk/ch...

Simple Summary The study aimed to describe the fatty acids, polyphenols, and antioxidant activity of goat’s milk from five different feeding systems: Grazing; conventional diet; and conventional diet supplemented with 10, 20, and 30 percent of Acacia farnesiana pods. Conventional diet showed the highest content of polyunsaturated fatty acids while...

In the present article we describe the spectroscopic data of ¹H and ¹³C Nuclear Magnetic Resonance of 11 compounds including: Nine natural products from the hexanic-chloroformic and methanolic extracts of Acacia farnesiana fruit and two esterified derivatives (22E-stimasta-5,22-dien- 3β-acetyl and methyl 3,4,5-triacetyloxybenzoate). Data linked to...

El género Leucaena Benth es un grupo de especies leñosas dentro de la tribu Mimoseae. El centro de biodiversidad biológica de Leucaena se localiza en el suroeste de México en el estado de Oaxaca. El nombre de Oaxaca deriva precisamente de oaxin, nombre dado a los frutos y árboles de este género de leguminosas (Zarate 1994). La diversidad y presenci...

Ethnopharmacological relevance: In Mexico, plants are an important element of traditional medicine, and many are considered part of Mexican cultural heritage from prehispanic and colonial times. Nevertheless, relatively few systematic scientific studies have been conducted to fully characterize the chemical composition and pharmacological activitie...

Background: Acacia farnesiana (AF) pods have been traditionally used to treat dyspepsia, diarrhea and topically for dermal inflammation. Main objectives: (1) investigate the antioxidant activity and protection against oxidative-induced damage of six extracts from AF pods and (2) their capacity to curb the inflammation process as well as to down-reg...

En el estado de Chiapas casi toda la ganadería bovina se desarrolla en condiciones de pastoreo extensivo, característica principal por la cual se busca transitar hacia la ganadería orgánica. En los últimos años ha crecido el interés por impulsar el desarrollo de sistemas de producción animal sostenible, de los que se espera contribuyan a una relaci...

En el presente estudio se investigó el contenido de compuestos bioactivos y la actividad antioxidante de leche caprina proveniente de 5 grupos de cabras Alpina francesa bajo distintos tratamientos dietarios: 1) dieta base (DB) constituida por 40% heno de alfalfa, 26.6% ensilado de maíz y 33.3% alimento concentrado; 2) pastoreo libre (P); 3) DB más...

Background Obesity is a worldwide public health issue, reaching epidemic condition in developing countries associated to chronic diseases. Oxidative damage is another side effect of obesity. Antioxidant activity from plant components regulates at some extent this imbalance. Main goal of the present study was to determine the antioxidant activity an...

El libro “Los Alimentos Orgánicos en la Salud: Mitos, realidades y perspectivas” no pretende ser exhaustivo, es un documento introductorio que contribuye a incrementar el acervo sobre la importancia de los alimentos orgánicos y su relación con la salud. Precisando que la generación de información es dinámica y permanente. Esperamos que las personas...

Agro-industrial co-products as fruit peel can be used as alternative and cheap fiber and prebiotics resources. The objective of this work was to evaluate rats’ in vivo physiological effect the in vivo effect of apple marc and cactus pear peel during 90 days. Inulin (as control) containing diet resulted in higher average body weight, but apple marc...

Dairy products are important sources of valuable nutrients. However, it is feared that some of their components, particularly the lipid fraction, may contribute to health problems. In the present research, 21 commercial soft goats' milk cheeses of the three varieties: Sainte-Maure, Feta, and Panela were assessed regarding their radical scavenging a...

En los últimos años ha crecido el interés por impulsar el desarrollo de sistemas de producción animal sostenibles, de los que se espera contribuyan a una relaci6n equilibrada entre factores ambientales, socioculturales y económicos. Por otro lado, los consumidores demandan alimentos de la más alta calidad y no solo en materia nutrimental, sino hast...

En los últimos años ha crecido el interés por impulsar el desarrollo de sistemas de producción animal sostenibles, de los que se espera contribuyan a una relaci6n equilibrada entre factores ambientales, socioculturales y económicos. Por otro lado, los consumidores demandan alimentos de la más alta calidad y no solo en materia nutrimental, sino hast...

Abstract. The World Health Organization points out that a safe food is one that is free of contaminants, does not represent risks, nor does it cause harm to the health of consumers. It also recognizes that food safety as an essential attribute of public health, and has the function of protecting the consumer from exposure and risks associated with...

Abstract. Bioactive components are defined as essential and non-essential compounds (for example vitamins and polyphenols) found in nature, as part of the food chain, must demonstrate a positive effect on human health, beyond the commonly known nutritional value. Resumen. Los componentes bioactivos son definidos como compuestos esenciales y no esen...

Organic agriculture and livestock farming is claimed to promote animal welfare and can offer animal products with better hygienic-sanitary quality, based on principles of health, ecology, fairness, and care. However, no clear advantages of organic milk (OM) versus conventional milk (CM) from tropical conditions are available. The aims of the study...

"Se presenta una conceptualización teórica de la innovación socioambiental y cómo ésta contribuye al desarrollo rural, entendido como un proceso de largo plazo y planeado a partir de acciones de investigación y desarrollo acorde al contexto y los problemas sobre los cuales se desea actuar. En este sentido, este capítulo aborda una experiencia a par...

In the current situation of agriculture, organic livestock farming has been not only adapted to ameliorate undesirable impacts on environment but also it is challenged to hold or improve agricultural yields obtained by conventional agriculture. In the Mesoamerican biological corridor, a region recognized with an abundant diversity, almost all anima...

The first goal of this study was to evaluate the chemical composition of vegetation consumed by goats on semiarid rangelands. Secondly, antioxidant activity and identified bioactive compounds of this vegetation were estimated. Twenty-five samples were analysed, including leaves, stems, fruits, or a combination of them. Chemical composition demonstr...

a b s t r a c t In the municipality of Tecpatan, Chiapas, in southeastern Mexico, it is highly feasible to convert tradi-tional agrosilvopastoral systems of dairy production to the organic production model. The objective of this study was to characterize silvopastoral systems and evaluate the feasibility of converting traditional agrosilvopastoral...

In the municipality of Tecpatan, Chiapas, in Southeastern Mexico, traditional agrosilvopastoral systems of dairy production have great potential for conversion to the organic production model. The objective of this study was to characterize silvopastoral systems and evaluate the potential of converting traditional agrosilvopastoral systems to the o...

Abstract. This article provides a theoretical conceptualization of socio-environmental innovation, applied to a research-action process aimed towards transition of conventional to organic cattle-raising in Tecpatan, Chiapas. We discuss: i) the cattle raising context analyzing technological, economic, and social indicators for agricultural productio...

Four groups of ten Creole male goat kids grazed without supplementation in a caducifolious forest located in Guerrero state, Mexico. Animal performance, carcass yield, protein, ash, moisture, total fat, fatty acid profile, polyphenol, caf-feic acid and catequine evaluations were performed (Longissi-mus dorsi muscle). Lower weight gains during summe...

In order for the meat goat producer to survive, new avenues for marketing goats must be created. Quality of food products is determined by their sensory attributes, chemical composition, physical properties, microbiological characteristics, shelf life, packaging and labeling. Cooked ham is one of the most popular processed meat products with value-...

The objective of this study was to evaluate the effect of foraging on local scrubby rangeland versus stable feeding with high-protein concentrate as well as the compulsory pasteurization process on goats' milk and artisan soft cheese quality in terms of chemical composition and fatty acid profile. The results indicated that there were no significan...

A study was conducted to evaluate the effect of feeding management and seasonal variation (summer and winter 2007) on fatty acid composition of Mexican soft raw goats’ milk cheese. Four groups were formed. During the summer, group A grazed on a natural semiarid rangeland. group B was kept in confinement, fed with concentrate grains and lucerne hay....

With the objective of evaluating the ruminal kinetics and growth of kids supplemented with a lactic acid bacteria (LAB) probiotic, 86 Alpine animals were assigned to a trial for 120 days. In treatment 1 (T1), 43 kids received a diet constituted by 50% alfalfa hay, 40% commercial concentrate and 10% slow intake nitrogen feed (ID). The animals in tre...

Two feeding systems trials were carried out to determine the antioxidant activity of soft goats' milk cheeses, and also to evaluate the presence of bioactive polyphenolic compounds. Two groups (A and B), each one with 20 (BW 50+/-5 kg) French Alpine goats were employed. All animals had between 70 to 80 milking days and were milked once a day. Group...

A group (A) of 20 female French Alpine goats (50 ± 5 Kg BW) were fed on summer semiarid vegetation in Querétaro, México. Other group (B) with similar characteristics was fed in full confinement with Lucerne hay and concentrate food made of cereals. The different diets were offered for 15 days before the trial. Browsing goats did not eat other feed....

A study was conducted to evaluate the effect of grazing on the nutritional composition of artisan soft goat cheese. Groups A and B were formed. Group A was managed with supplementation on goats grazing in the semiarid rangeland. Group B goats were kept full indoors fed with lucerne hay and grain concentrate. Results indicated that feeding system an...

With the objective of evaluating the ruminal kinetics and growth of kids supplemented with a lactic acid bacteria (LAB) probiotic, 86 Alpine animals were assigned to a trial for 120 days. In treatment 1 (T1), 43 kids received a diet constituted by 50% alfalfa hay, 40% commercial concentrate and 10% slow intake nitrogen feed (ID). The animals in tre...

aquatic Some aquatic plants are nutritionally comparable to forage crops (Helfron et al. 1977). The principal limitation in their utilization in Iivestock feeding is high moisture content (about 90%) but this can be resolved by drying or ensiling (Linn et al. 1975ab). The other limitation is rapid spoilage of aquatic plants although some plants lik...

Ruminal cannulated crossbred sheep (70±2 kg BW) were used to measure the effects of different levels of the aquatic plant Schoenoplectus americanus Volkart (SA) on a basal diet consisting of forage oats (Avena saliva) supplemented with 30% of a slow release urea supplement (SRUS). The diets (D1, D2, and D3) included 0%, 20% and 40% SA. SRUS was mad...

One hundred and eighty Pelibuey lambs were fattened for 120 days with three treatments evaluating in situ DM disappearance, voluntary DM or OM intake, rumen degradation, rate of passage, NH3 and VFA concentration, apparent digestibility, ruminal pH, total fermentable carbohydrates and weight gains. The first diet (T1), 60 lambs (25.7±0.7kgBW) plus...

Ruminal cannulated crossbred sheep (70*2 kg BW) were used to measure the effects of different levels of the aquatic plant Schoenoplectus americanus Volkari (SA) on a basal diet consisting of forage oats (Avena sativa) supplemented with 30% of a slow release urea supplement (SRUS). The diets (Dl, D2, and D3) included 0%, 20% and 40% SA. SRUS was mad...

Eighty-six Alpine kids, 18.765 (±0.510) kg BW, plus four cannulated adult goats were allocated to two treatments in a production trial lasting 150 days. They also were evaluated for in situ DM disappearance, VDMI, OMI, rumen degradation rate of passage, NH3 and VFA concentrations, apparent digestibility, pH, total fermentable carbohydrates, and wei...

One hundred and sixty Alpine kids (16kg BW) were studied for 150 days with two diets, evaluating in situ DM disappearance, VDMI, OMI, rumen degradation, rate of passage, ammonia (NH3) and volatile fatty acids (VFA) concentrations, apparent digestibility, pH, total fermentable carbohydrates (FC), and BW gains. Group 1, designated as CS/SIUS (n=80 pl...

A study was conducted on 14 ha of Caducifolia thorny forest with an average total dry matter yield of 800 kg/ha/year. The area of study was divided into two 7 ha camps. Thirty-five Alpine goats were allocated to one of the camps in a continuous grazing system, called the free grazing (FG) camp treatment. Another 35 goats were placed in the other ca...

Ninety Zebu bulls of 203 kg (37) fattened with Cynodon nlemfuensis, C. dactylon, Panicum maximum and Brachiaria brizantha were divided in 2 groups in Mexico. The first group (48 bulls) received 2 kg/day of a mixture of catalytic complex feed (CCF). CCF is composed of molasses (16%), urea (5%), harinolina (16%), rice bran (12%), maize (16%), poultry...

Ninety Zebu bulls of 203 kg (37) fattened with Cynodon nlemfuensis, C. dactylon, Panicum maximum and Brachiaria brizantha were divided in 2 groups in Mexico. The first group (48 bulls) received 2 kg/day of a mixture of catalytic complex feed (CCF). CCF is composed of molasses (16%), urea (5%), harinolina (16%), rice bran (12%), maize (16%), poultry...

A 1-year study was conducted to measure the forage volume necessary to maintain a goat herd in the semiarid zone of Mexico in terms of economic feasibility and seasonal grazing to conserve range land. The average weight of the adult females was 53 ± 5 kg and yearlings weighed 40 ± 3 kg at first kidding. Average milk production was 400 ± 67 kg in 21...

RESUMEN. Con el objetivo de determinar el efecto de un suplemento líquido de bacterias acidolácticas (SULIBAL) sobre la fermentación ruminal y utilización de dietas mixtas de alfalfa o rastrojo de maíz y concentrado comercial, se alimentaron cuatro ovinos machos adultos (52 ± 10 kg), dotados con cánulas ruminales, con los tratamientos (%): T1 (alfa...