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27
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Introduction
Publications
Publications (27)
Background
Both CMV and Rubella virus infections are associated with the risk of vertical transmission, fetal death or congenital malformations. In Angola, there are no reports of CMV and Rubella studies. Therefore, our objectives were to study the seroprevalence of anti-CMV and anti-Rubella antibodies in pregnant women of Luanda (Angola), identify...
Background
HIV and HBV infections remain responsible for high rate of morbidity and mortality in many African Countries, affecting women and newborns. This study aims to analyze the spatial pattern of HIV and HBV infections in pregnant women in Luanda, Angola, and the statistical association between HIV and HBV and socio-economic characteristics, h...
The present work evaluated the surveillance of the drinking water quality information system database and correlated the findings of the microbiological analysis with the distribution of intestinal protozoa from the metropolitan region of Rio de Janeiro. From the database, we obtained 1,654 georeferenced monitoring stations that were used in the an...
Background: The main objective was to study the seroprevalence of anti-CMV and anti-Rubella antibodies in pregnant women of Luanda (Angola), identify the primary maternal infection during gestation and to evaluate the socio-demographic risk factors associated with CMV and Rubella virus infections.
Methods: A prospective cross-sectional study was co...
We report a study on toxoplasmosis in pregnant women in Luanda, Angola, determining the seroprevalence, geospatial distribution and its association with socioeconomic features, dietary habits and hygiene and health conditions. Anti-Toxoplasma gondii IgG and IgM were quantified in serum samples of women attended at the Lucrecia Paim Maternity Hospit...
The protozoan Giardia lamblia is the most common cause of parasitic gastrointestinal infection worldwide. The parasite developed sophisticated, yet not completely disclosed, mechanisms to escape immune system and growth in the intestine. To further understand the interaction of G. lamblia with host immune cells, we investigated the ability of paras...
Giardia lamblia is an intestinal parasite that has an extensive genetic variation among isolates. This species is divided into eight different assemblages (A–H), but only assemblages A and B have been associated with human infections. Studies on the associations of G. lamblia assemblages and symptoms have been done but were inconclusive. The aim of...
Background:
Intestinal parasitic infections remain among the most common infectious diseases worldwide. This study aimed to estimate their prevalence and provide a detailed analysis of geographical distribution of intestinal parasites in the metropolitan region of Rio de Janeiro, considering demographic, socio-economic, and epidemiological context...
Number of positive and negative participants to intestinal parasites by regions.
(DOCX)
Population density of Rio de Janeiro state.
(TIF)
STROBE checklist.
(DOC)
Background
Despite the high prevalence of giardiasis, the genetic characterization of Giardia lamblia has been poorly documented in Brazil and molecular epidemiology research has only been conducted in the last few years. The aim of this study was to determine the prevalence of different G. lamblia assemblages and detect mixed infections among pati...
Threshold cycle values.
(DOCX)
Genotyping of 65 G. lamblia positive samples based on ssu rRNA, bg, gdh, tpi and orfC4 genes.
(DOCX)
The antibody response to Plasmodium falciparum parasites of naturally infected population is critical to elucidate the role of polymorphic alleles in malaria. Thus, we evaluated the impact of antigenic diversity of repetitive and family dimorphic domains of the merozoite surface protein 2 (MSP-2) on immune response of 96 individuals living in Peixo...
The genetic polymorphism of the surface merozoite protein 2 (MSP-2) was evaluated in Plasmodium falciparum isolates from individuals with uncomplicated malaria living in a Brazilian endemic area of Peixoto de Azevedo. The frequency of MSP-2 alleles and the survival of genetically different populations clones in 104 isolates were verified by Souther...
Projects
Project (1)
Giardiasis is an intestinal parasitic infection that remains among the most common infectious diseases worldwide. Despite the high prevalence, the epidemiology of giardiasis and other intestinal parasites has been poorly documented in Brazil, principally in Rio de Janeiro State. Giardia lamblia is considered a species complex, whose members show little variation in their morphology but presents a remarkable genetic variability. The genetic characterization of G. lamblia has been poorly reported and molecular epidemiology researches have been conducted in the last few years. Therefore, the work aimed to (i) estimate the prevalence and provide a detailed analysis of geographical distribution of intestinal parasites in Rio de Janeiro, considering demographic, socio-economic, and epidemiological contextual factors; (ii) determine the prevalence of different G. lamblia assemblages and detect mixed infections; (iii) identify G. lamblia inter and intra-assemblage level of genetic variation; and (iv) correlate assemblages with symptoms in patients with and without HIV/AIDS. The cross-section survey was conducted among patients attending the Evandro Chagas National Institute of Infectious Diseases (FIOCRUZ, Rio de Janeiro).
