About
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Introduction
Social and territorial inequalities in health. Mapping breast cancer screening
Additional affiliations
September 2015 - present
Position
- Geographic variations of breast cancer incidence using GIS and spatial analysis, France
September 2011 - December 2011
Boston School of Public Health, US
Position
- Spatial analysis of the relation social inequality and environment and health in France using mapping disease with GAM
October 2009 - August 2015
Position
- Cumulative effect of environment on social inequalities in health in France
Publications
Publications (80)
Background:
The detection of cancer in its early latent stages can improve patients' chances of recovery and thereby reduce the overall burden of the disease. Our objectives were to investigate factors (geographic accessibility and deprivation level) affecting mammography screening participation variation and to determine how much geographic varia...
Objectives
Despite evidences of efficiency and safety ambulatory endovascular revasculatisation for lower extremity arterial disease (LEAD) concerned only 5% of the interventions in France in 2016. Such low rate suggested temporal and geographical space disparities. The aim of this study was to describe the space-time development of ambulatory endo...
Background
The population living in urban areas is growing rapidly. The level of exposure to adverse environmental factors is detrimental to human health and is directly related to urban and transport planning practices.
Objective
To estimate the premature mortality burden of non-compliance with international exposure guidelines for air pollution,...
Background
Mapping the spatial distribution of disease occurrence is a strategy to identify contextual factors that could be useful for public health policies. The purpose of this ecological study was to examine to which extent the socioeconomic deprivation and the urbanization level can explain gender difference of geographic distribution in strok...
A survey was conducted throughout Gabon to search simultaneously for Human T-Lymphotropic Virus type 1 (HTLV-1) using quantitative polymerase chain reaction (qPCR) and the serological method as well as filarial infection on the same sample by direct examination of 10 µL of blood and the concentration technique. 3728 samples were analyzed, showing t...
Introduction
The detection of breast cancer in its latent stages through mammography screening can improve patient's chances of recovery. However, geographic variation in mammography participation remains. Our objectives were first to assess whether the geographic accessibility of mammography-screening services influences mammography-screening part...
Background: Stroke remains a devastating disease in Europe and geographic disparities persist. Mapping spatial distributions of disease occurrence can serve as a useful tool for identifying exposures of public health concern. The purpose of this study was to investigate geographic differences in relationship between socioeconomic, clinical, urban-r...
Introduction
Mammography screening can reduce breast cancer mortality among women aged 50 years and older. Small geographic areas with lower breast cancer screening uptake may reflect gaps in screening efforts. Our objective was to identify the geographic variations of breast cancer screening uptake among women aged 50-74 years in the Lyon Metropol...
Introduction
Despite major improvements in management over recent decades, stroke remains a devastating disease in Europe and geographic disparities persist. Determining the spatial distribution of stroke may be useful for both epidemiological research and health services planning. The aim of this study was to estimate stroke incidence rates in Pay...
Background and Purpose—
Recent findings suggest that in the United States, stroke incidence is higher in rural than in urban areas. Similar analyses in other high-income countries are scarce with conflicting results. In 2008, the Brest Stroke Registry was started in western France, an area that includes about 366 000 individuals living in various u...
Small geographic areas with lower mammography screening participation rates may reflect gaps in screening efforts. Our objective was to use spatial analyses to understand disparities in mammography screening use and to identify factors to increase its uptake in areas that need it in Lyon metropolitan area, France. Data for screened women between th...
Emergency first dialysis start considerably increases the risk of morbidity and mortality. Our objective was to identify the geographic variations of emergency first dialysis risk in patients with end-stage renal disease in the Bretagne region, France. The spatial scan statistic approach was used to determine the clusters of municipalities with sig...
HTLV-1 infection is considered as highly endemic in central Africa. Thirty years ago, a first epidemiological study was performed in Gabon, central Africa, and revealed that the prevalence varied from 5.0 to 10.5%. To evaluate current distribution of HTLVs in Gabon, 4.381 samples were collected from rural population living in 220 villages distribut...
Introduction
D’après les données du registre REIN, 34 % des cas incidents hémodialysés en 2015 ont démarré la dialyse en urgence. Le recours à la dialyse en urgence augmente le risque de morbidité et de mortalité et diminue la qualité de vie des patients. Une bonne coordination entre le médecin généraliste et le néphrologue pendant la période pré-d...
Introduction
Le recours au démarrage en urgence de la dialyse chez les insuffisants rénaux chroniques terminaux augmente considérablement le risque de morbidité et de mortalité et diminue la qualité de vie des patients. L’objectif de cette étude est d’analyser les disparités géographiques de démarrage en urgence de la dialyse en Bretagne et de déte...
Background: Despite improvements, air pollution still remains a major public health issue. Numerous epidemiological studies have demonstrated the adverse health effects of air pollution exposure based on modeled measures, but only a few have considered the health impact of perceived air quality. Improving our knowledge of individual perceptions is...
This study aims to assess the evidence on adverse pregnancy outcome associated with living close to polluted industrial sites, and identify the strengths and weaknesses of published epidemiological studies. A systematic literature search has been performed on all epidemiological studies published in developed countries since 1990, on the associatio...
Background
An environmental health inequality is a major public health concern in Europe. However just few studies take into account a large set of characteristics to analyze this problematic. The aim of this study was to identify and describe how socioeconomic, health accessibility and exposure factors accumulate and interact in small areas in a F...
Background
We conducted this systematic review and meta-analysis to address the open question of a possible association between the socioeconomic level of the neighborhoods in which pregnant women live and the risk of Congenital Heart Defects (CHDs), Neural Tube Defects (NTDs) and OroFacial Clefts (OFCs).
Methods
We searched MEDLINE from its incep...
Characteristics of the included studies regarding CHDs: the scores for each criterion and the quality index.
(DOCX)
Combined effect of neighborhood deprivation on congenital heart defects (CHDs), on neural tube defects (NTDs) and orofacial clefts (OFCs) taking into account the Quality index (Qi).
(DOCX)
Characteristics of the included studies regarding OFCs: the scores for each criterion and the quality index.
(DOCX)
Quality effect model methods.
(DOCX)
Characteristics of the included studies regarding NTDs: the scores for each criterion and the quality index.
(DOCX)
Objectif
L’objectif est d’évaluer les inégalités territoriales de santé en lien avec la mortalité infantile à une échelle fine, en analysant comment les indicateurs socioéconomiques, d’accès aux soins et d’expositions environnementales interagissent et s’accumulent entre eux sur le territoire.
Méthodes
À l’aide de systèmes d’informations géographi...
Background
An environmental health inequality is a major public health concern in Europe. However just few studies take into account a large set of characteristics to analyze this problematic. The aim of this study was to identify and describe how socioeconomic, health accessibility and exposure factors accumulate and interact in small areas in a F...
Today, one important challenge in developed countries is health inequalities. Research conducted in public health policy issues supply little evidence for effective interventions aiming to improve population health and to reduce health inequalities. There is a need for a powerful tool to support priority setting and guide policy makers in their cho...
Infant and neonatal mortality indicators are known to vary geographically, possibly as a result of socioeconomic and environmental inequalities. To better understand how these factors contribute to spatial and temporal patterns, we conducted a French ecological study comparing two time periods between 2002 and 2009 for three (purposefully distinct)...
Many epidemiological studies examining long-term health effects of exposure to air pollutants have characterized exposure by the outdoor air concentrations at sites that may be distant to subjects' residences at different points in time. The temporal and spatial mobility of subjects and the spatial scale of exposure assessment could thus lead to mi...
Health geographics is a fast-developing research area. Subjects broached in scientific literature are most varied, ranging from vectorial diseases to access to healthcare, with a recent revival of themes such as the implication of health in the Smart City, or a predominantly individual-centered approach. Far beyond standard meta-analyses, the prese...
[This corrects the article DOI: 10.1371/journal.pone.0131463.]
Spatial Planning of Green Space as a Local Intervention Aimed at Tackling Social Health Inequalities: Adverse Pregnancy Issues
Empirical support for the potential of green space to play a role in reducing the risk of adverse pregnancy outcomes (including infant mortality) has now been documented. Uneven proximity and/ or access to green space thus...
Background – The relationship between the characteristics of the neighbourhoods where people live and health inequalities is now well documented. More specifically, socioeconomic characteristics have been indicated as mediating the health effect of environmental exposure; this is most documented in relation to air pollution. Two mechanisms have bee...
Background
While a great number of papers have been published on the short-term effects of air pollution on mortality, few have tried to assess whether this association varies according to the neighbourhood socioeconomic level and long-term ambient air concentrations measured at the place of residence. We explored the effect modification of 1) soci...
In order to study social inequalities, indices can be used to summarize the multiple dimensions of the socioeconomic status. As a part of the Equit'Area Project, a public health program focused on social and environmental health inequalities; a statistical procedure to create (neighborhood) socioeconomic indices was developed. This procedure uses s...
Several studies have investigated the implication of biological and environmental factors on geographic variations of end-stage renal disease (ESRD) incidence at large area scales, but none of them assessed the implication of neighbourhood characteristics (healthcare supply, socio-economic level and urbanization degree) on spatial repartition of ES...
Everyone is subject to environmental exposures from various sources, with negative health impacts (air, water and soil contamination, noise, etc.or with positive effects (e.g. green space). Studies considering such complex environmental settings in a global manner are rare. We propose to use statistical factor and cluster analyses to create a compo...
Congenital anomalies are the main causes of preterm and neonatal mortality and morbidity. We investigated the association between congenital anomalies and mothers' exposure to air pollution during pregnancy by combining risk estimates for a variety of air pollutants (SO2, NO2, PM10, PM2.5, CO and O3) and anomaly defect outcomes. Seventeen articles...
Few studies have explored how noise might contribute to social health inequalities, and even fewer have considered infant mortality or its risk factors as the health event of interest.In this paper, we investigate the impact of neighbourhood characteristics - both socio-economic status and ambient noise levels - on the spatial distribution of infan...
L'existence des inégalités sociale de santé (ISS) est solidement établie en France. La mortalité infantile et néonatale sont reconnues comme des indicateurs de l'état de santé d'une population. En dépit de nombreux facteurs de risques déjà identifiés, une part des ISS demeurent inexpliquées ; les nuisances environnementales sont suspectées. L'objec...
Few studies have considered using environmental amenities to explain social health inequalities.Nevertheless, Green spaces that promote good health may have an effect on socioeconomic health inequalities. In developed countries, there is considerable evidence that green spaces have a beneficial effect on the health of urban populations and recent s...
Introduction
In order to study social health inequalities, contextual (or ecologic) data may constitute an appropriate alternative to individual socioeconomic characteristics. Indices can be used to summarize the multiple dimensions of the neighborhood socioeconomic status. This work proposes a statistical procedure to create a neighborhood socioec...
In France, reducing social health inequalities has become an explicit goal of health policies over the past few years, one of its objectives is specifically the reduction of the perinatal mortality rate. This study investigates the association between infant mortality and social deprivation categories at a small area level in the Lille metropolitan...
Résumé. Afin d'étudier l'existence d'inégalités sociales de santé, les données contextuelles constituent une bonne alternative aux caractéristiques socioéconomiques individuelles souvent difficilement accessibles. Des indices peuvent être utilisés pour synthétiser les multiples dimensions du statut socioéconomique. Dans ce contexte, les objectifs p...
Prevalence and mean of
Loa loa
and
Mansonella perstans
microfilaremia in surveyed villages.
(DOC)
Background:
In Gabon, several Ebolavirus outbreaks have occurred exclusively in the northeastern region. We conducted a large serosurvey to identify areas and populations at risk and potential demographic, clinical, and behavioral risk factors.
Methods:
Blood samples and clinical and sociodemographic data were collected from 4349 adults and 362...
The filarial parasites Loa loa and Mansonnella perstans are endemic in the central and western African forest block. Loa loa is pathogenic and represents a major obstacle to the control of co-endemic filariae because its treatment can cause fatal complications such as encephalitis.
4392 individuals aged over 15 years were studied both by direct exa...
Rapidly spreading to new regions, including the islands of the Indian Ocean, Central Africa, and Europe, Chikungunya fever is becoming a major problem of public health. Unlike other members of the alphavirus genus, immune responses to Chikungunya virus (CHIKV) have been poorly investigated.
We conducted a large ex vivo multiplex study of 50 cytokin...
The objective of the study was to investigate the association between infant mortality, deprivation and proximity to polluting industries in Lille between 2000 and 2009. The geographical unit used was the smallest French census block: the Iris. Information on infant deaths was collected from local authorities. These data include the family address,...
Background
Dengue is now a leading cause of morbidity and mortality throughout the tropics. We conducted the first ex vivo study of dengue fever (DF) in African patients infected during the first Gabonese dengue virus 2 (DENV-2) outbreak in 2007, in order to investigate cytokine production, including the antiviral cytokine IFN-α, reported to be a p...
Cytokines, chemokines and growth factors unchanged in DF patients compared to controls (p > 0.05) throughout the acute phase. Levels are expressed in pg/mL, according to the day of sampling after symptom onset. Mean control (CTL) levels are shown in red. The vertical bars represent the standard deviation. One patient was sampled on day 0, seven on...
Detection of six unmodified circulating inflammatory cytokines in fatal (red plots, D) and nonfatal (green plots, S) clinical cases of ZEBOV infection. Fatal and nonfatal cases were each subdivided into two groups according to the interval between symptom onset and blood sampling, as follows: S1 and D1 sampled 1–4 days after symptom onset, S2 and D...