Cidéli CoelhoUniversidade Santo Amaro (UNISA) · Campus I
Cidéli Coelho
PhD
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88
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Introduction
Additional affiliations
June 2012 - present
Position
- Professor Researcher
Publications
Publications (88)
Background
Platynosomiasis in non‐human primates kept under human care causes chronic disease of the bile ducts and liver, which initially presents with nonspecific signs and can culminate in the death of the animal. Diagnosing this disease is a challenge, and an ultrasound examination can be an excellent tool when it is suspected.
Methods
This st...
Background Carduus marianus is a Mediterranean plant used for treating liver diseases. One of its properties is that it inhibits fat peroxidation, which can contribute toward the prevention of metabolites that are harmful to the liver.
Objective The aim of this study was to describe the treatment of fatty liver disease in an axolotl (Ambystoma mexi...
During embryological development, the eyelids of snakes fuse and no longer open like in mammals. They become transparent, thus forming spectacles, a transparent structure that covers the eyes. The primary function of these spectacles is to provide a physical barrier to protect the eyes without eyelids. This study aimed to evaluate the ocular biomet...
Dilated cardiomyopathy (DCM) is a disease of the heart muscle diagnosed by alterations resulting from ventricular systolic dysfunction with enlargement of the heart chambers, which is still underdiagnosed in non‐human primates. This report is the first case of the DCM phenotype diagnosed by echocardiography and confirmed by necropsy in Callithrix p...
Reports of sarcomas in nonhuman primates are scarce and, specifically, primary hepatic sarcomas are rare, as in humans. This is the first report of an aggressive hepatic fibrosarcoma in a young adult Callithrix jacchus. The final postmortem diagnosis was obtained by means of immunohistochemical analysis, which confirmed the tumor histogenesis.
Foi avaliado o tratamento homeopático de um felino com doença renal policística, moléstia hereditária muito comum na espécie felina. Por ser progressiva, o prognóstico depende do estágio de evolução da doença renal crônica, da resposta do felino ao tratamento inicial e do desejo do tutor em dar continuidade ao tratamento. A observação teve duração...
Pulmonary ultrasonography may be useful for early diagnosis and management of respiratory complications. The combination of air and soft tissues confirms imaging artifacts that may contribute to differentiation of healthy lung tissue from deteriorated lung tissue. Although non-human primates are often chosen as research models due to similarity to...
Background Folliculinum is a homeopathic sarcode medication that is mainly used for regulating the estrous cycle and reproductive function. In snakes, it is common to observe low frequencies of reproduction. Ovulation is related to follicular size and morphology, and follicle homogeneity may indicate the absence of problems such as dystocia (egg re...
A poluição ambiental causada por resíduos de metais pesados, que são desreguladores endócrinos, é muito relevante por seu amplo uso em processos industriais e agrícolas. O Chumbo é um metal pesado altamente tóxico ao meio ambiente e à organismos como peixes e invertebrados aquáticos. Este trabalho tem como objetivo avaliar as alterações comportamen...
Background and Aims Penguins are seabirds that manifest physiological and immunological alterations during the reproductive season. The objectives of this study were to evaluate the laboratory parameters of male and female Magellanic penguins and to determine the penguins' hematological response to homeopathic medicines during that reproductive per...
Introduction: two Python bivittatus were received at Project Selva Viva, zoo in Taubaté, Brazil, both presented respiratory noises and oro-nasal discharge. In view of the fact, a thoracic ultrasonographic examination was performed for evaluation on February 25, 2022, which diagnosed the presence of multiple vertical hyperechoic artefacts emerging f...
Background: Leukopenia is associated with the consumption of peripheral leukocytes, decreased production due to endotoxemia and septicemia, medullary hypoplasia, nutritional diseases or autoimmune reactions. In a case report by Narita et al, Echinacea angustifolia demonstrated the effectiveness of treatment of leukopenia in penguins. Aims: Report t...
Background: Hyperadrenocorticism is a common endocrinopathy in dogs, associated to an excessive production or administration of cortisol. Aims: Report the evolution of homeopathic treatment in hyperadrenocorticism of a yorkshire male dog with 10 years old, analyzing with basal and post-acth stimulation cortisol values. Methodology: Homeopathic trea...
Background: The truths surrounding medical practices are seasonally challenged by innovative concepts that can aggregate changing procedures in many degrees. The Galtonian eugenics issues supported the pure-breed idea in dictatorial governments, and introduced mesological studies, turning possible to join genetic concepts to the physiology and psyc...
The present study to report the dissolution of calculus in the ureter in a kitten.
Morphological and functional changes during senility give rise to changes to organs and tissues. Even in healthy dogs, laboratory parameters may differ, thus making preventive treatment difficult. The aim of this study was to evaluate hematological and biochemical parameters in elderly and geriatric dogs and to compare them for follow-up and possib...
Background: Mercury is used in various industrial. Part of Mercury's industrial waste is discharged into the environment, rivers and their tributaries, thus contaminating aquatic animals. Aim: to evaluate Mercury-induced behavioral changes in Zebrafish (Danio rerio) by the analysis of locomotor activity and parameters related to neurotoxicity and t...
Background: Excess weight causes disorders in locomotor, cardiorespiratory and reproductive systems and increases the incidence of endocrinopathies, as well it can often cause dyslipidemias, leading to atherosclerosis. Aims: Report the evolution of homeopathic treatment in 4 overweight patients, being 2 female dogs and 2 female rabbits with hypertr...
Background: A 3-year-old male cockatiel (Nymphicus hollandicus) was diagnosed with joint arthritis due to hyperucemia syndrome. The bird presented deposition of urate crystals on the synovial membrane with inflammation of joints and tendons (tufts), causing listlessness, anorexia and lameness, with difficulty in keeping perched or moving. Laborator...
Background: Uric acid is the main form of excretion of nitrogenous components in birds. The assessment verification samples, control, check of uric acid concentrations is widely used to detect kidney disease. High concentrations (up to five times) of uric acid in plasma can lead to the precipitation of this acid in the form of crystals, which accum...
Keeping Neotropical primates in captivity puts them at great risk of illness because of their susceptibility to human herpesvirus. This is the first report on herpesvirus in Callicebus nigrifrons that developed clinical disease and was confirmed by immunohistochemical and RT‐PCR. Diagnosis and prevention are essential for the conservation of specie...
A homeopatia é uma medicina utilizada desde meados do século XVIII, utilizada em humanos e em animais, com seus benefícios e ausência de reações adversas, houve a expansão também para o uso no meio ambiente, através da utilização em plantas e no solo, visando o bem-estar de todo ser vivo e pensando no todo e na saúde do planeta, assim como a aborda...
Em mulheres é comum o relato de varizes pélvicas, especialmente após gestações. Entretanto, em cadelas é raro, devido a anatomia e escassez de estudos. Este relato se refere a presença de varicose diagnosticada por exame ultrassonográfico em uma cadela Bull Terrier, de dois anos de idade, após parto distócico de um feto. O diagnóstico pode ser prom...
Separation Anxiety (SA) is a behavioral syndrome that may affect dogs of different ages and that is characterized by intense clinical signs. Traditional veterinary clinic efforts rely on harmful side effect drugs. Overall, homeopathy handles individual idiosyncrasies and susceptibilities and deal with them using a single medicine through the law of...
Introduction: Biotherapics are medicines prepared from etiologic agents, following Brazilian Homeopathic Pharmacopeia. Influenza is a disease that affects thousands of people worldwide every year, motivating the development of new therapies. Aim: In this study, we developed two biotherapics from live/active influenza A virus, at 12x and 30x, and ve...
In previous studies, it was found that thymulin (thymic hormone), when prepared in homeopathic 5CH dilution, can modulate diseases progress and immune processes, such as virus infection in poultry and experimental tumor development. This project aims to study the immune modulatory mechanisms of thymulin 5CH in granulomatous experimental model induc...
Background: It has been speculated that the homeopathic treatment of sperm cells in order to improve semen quality could be promising. However, few data is available and its use in spermatozoa requires investigation. It is well established that mitochondrial membrane potential is an important viability parameter of spermatozoa and it is intimately...
In previous studies it was found that thymulin 5cH (thymic hormone) can modulate immune processes in several diseases. Additionally, the Antimonium crudum has used in dogs bearing leishmaniosis, according to the similia principle. We studied the inflammatory and immune modulation by thymulin 5CH and Antimonium crudum 30CH treatment in mice experime...
Background: ZINCUM METALLICUM (ZM) is a homeopathic medicine whose materia medica is defined by diverse behavioral and mental symptoms, including depression. Moreover, as a microelement, zinc itself is involved in several functions of Central Nervous System, including development and cell maturity during the intra-uterus life. Aims: Herein, the put...
Introduction: The factors related to obesity are complex, involving biologic, environmental and neuropsychological mechanisms[1-3]. Among the factors which influence the gain of weight, we can consider the stressful factors. Aims: The aim of this experiment was to evaluate the influence of the commercial homeopathic product compound by Fucus vesicu...
Introdução: Piometra é caracterizada por infecção bacteriana aguda ou crônica, com acúmulo de exsudato em lúmen uterino e é um diagnóstico muito comum em cadelas não castradas, especialmente em fase de meia idade e mais velhas. O principal tratamento recomendado é a ovariohisterectomia, por ser o método mais seguro e eficaz e em alguns casos o trat...
Convulsões podem ser resultado de falhas na condução elétrica encefálica, decorrentes de alterações nos níveis de neurotransmissores. São as alterações neurológicas mais comuns na rotina clínica de pequenos animais, totalizando aproximadamente 1% a 2% dos casos atendidos. A ocorrência pontual de convulsões é classificada apenas como crise convulsiv...
Background Ovariohysterectomy (OH) is one of the most frequent elective surgical procedures in routine veterinary practice. Arnica montana is a well-known medicine in phytotherapy, with proven analgesic, anti-inflammatory, antiseptic, healing, antioxidant and immunomodulatory activity. However, there is still a shortage of studies on the action and...
Introduction: Post-operative period has been associated with risks like depression of cardiorespiratory system, hypothermia etc., especially under influence of anesthesia. Therefore, short anesthetic recovery in important. Aims: The objective of this study was to evaluate whether homeopathic drug Papaver somniferum 30cH can help reducing the durati...
Introduction: Escherichia coli (E. coli) is one of the most common agent involved in digestive and urinary tract infections (UTI). Aims: The objective of this study was to explore whether homeopathic/isotherapic preparations could interfere with pathophysiological aspects of murine cystitis induced by E. coli in an experimental model. Materials and...
Introduction: Clinical studies have shown that adverse events in childhood can lead to the development of psychiatric disorders, such as anxiety, in adolescence and adulthood in humans. Manipulations with laboratory animals, such as maternal deprivation (MD), are a source of stress for the offspring and can be a useful tool for the understanding ho...
Background: In previous studies the effect of homeopathic medicines in murine cutaneous Leishmaniasis were described, indicating immunomodulation. The phagocytes migration and their activity increased after Thymulin 5cH and decreased after Antimonium crudum 30cH treatment. Methods: The morpho-functional features of RAW macrophages co-cultured with...
Encephalitozoon cuniculi (E. cuniculi) is a fungus that behaves as an intracellular parasite infecting different types of cells. In rabbits and immunosuppressed animals of other species, including humans, it parasites neural tissues causing a highly characteristic neurological syndrome, for which repertory analysis indicates Phosphorus. Successful...
Aging is an extremely complex and multifactorial process. Over time, the elderly begin exhibiting signs of function reduction. The aim of the present study was to assess the effects of homeopathic medicines on testicle histomorphometry in senescence/senility. The study was approved by the animal experimentation ethics committee of Santo Amaro Unive...
Background: Clinical studies have shown that adverse events in early life are quite stressful and can lead to the development of psychiatric disorders, such as anxiety, in adolescence and adulthood in humans. Experimental models of maternal deprivation (MD) in rats can be a useful tool for the understanding how these events in the early period of d...
Introduction: The aim of the present study was to describe different biological aspects of Ehrlich tumor in mice, such as body weight evolution, tumor growth rate, histological organization and systemic immune response after treatment with high-diluted thymulin (10-9 M, named 5CH). Methods: Tumor assessment was focused on macro- and microscopic asp...
Background Mechanical trauma, bacterial and viral infections are common in Trachemys dorbigni when in captivity. Aims Report the evolution of homeopathic treatment in a patient of Trachemys dorbigni species. Methodology Homeopathic treatment was chosen, based on the principle of similitude, using Arnica montana due to its anti-inflammatory action,...
Background Thrombocytopenia is a decrease in the number of platelets in the blood resulting from disorders of production, distribution or destruction, leading to bleeding. The respective treatment of thrombocytopenia is usually based on corticotherapy and platelet transfusion. Aims Report the evolution of homeopathic treatment in a 12 years old Mal...
The objective of the present study was to identify the intestinal parasites with the highest prevalence in anatids that were reared extensively in the city of São Paulo, through coproparasitological examinations. Fecal samples (n=108) were collected at two times, with an interval of two months between them, during the year 2018. The samples were co...
Introduction Encephalitozoon cuniculi (E. cuniculi), a fungus that acts as an intracellular pathogen, causes a marked neurological syndrome in many host species and is a zoonotic concern. Although no well-established treatment for this syndrome is known, previous successful clinical experience using homeopathic phosphorus has been described in whic...
Introduction According to the “silica hypothesis” formulated to explain homeopathy, the information of starting materials would be transferred to cells by silica nanoparticles detached from the glassware walls by serial dilution and agitation through epitaxy. We compared the biological activity, electrical current and silicon microparticle content...
Objective:
This is a random blinded placebo controlled murine experimental model to study the effects of Cantharis 6 CH, a homeopathic medicine, on E coli-induced cystitis.
Methods:
24 adult susceptible female BALB/c mice were inoculated with E coli - UPEC O4:K-:H5 by a transurethral catheter. Cantharis 6cH or vehicle (placebo) was offered to mi...
Prenatal undernutrition impairs copulatory behavior and increases the tendency to become obese/overweight, which also reduces sexual behavior. Re-feeding rats prenatally undernourished with a normocaloric diet can restore their physiological conditions and copulatory behavior. Thus, the present study investigated whether a hypercaloric diet that is...
Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate the use of propentofylline as a depression treatment. We used a rat model of depression induced...
F and p of two-way analysis of variance.
Statistical values of F and p of two-way analysis of variance of body weight and open field general activity.
(DOCX)
F and p of one-way analysis of variance.
Statistical values of F and p of one-way analysis of variance of light-dark test, forced-swim test, plasmatic evaluations, and astrocyte GFAP expression.
(DOCX)
The main objective of the present study was to investigate whether male rats that receive a hypercaloric diet only during the juvenile period (Postnatal Day [PND] 23 to PND65) and a normocaloric diet thereafter exhibit changes in reproductive aspects in adulthood. Body weight gain during the juvenile period and adulthood and the morphology of adipo...
The present study investigated whether male offspring (F2 generation) from female rats (F1 generation) whose mothers (F0 generation) were food restricted during gestation inherit a phenotypic transgenerational tendency towards being overweight and obese in the juvenile period, in the absence of food restriction in the F1/F2 generations. Dams of the...
Background:
Influenza affects thousands of people worldwide every year, motivating the development of new therapies. In this work, the effects of two homeopathic preparations (influenza biotherapies and thymulin) were chosen following two different rationales: isotherapy and endo-isotherapy models. The homeopathic effects were evaluated individual...
Background: Leishmaniasis is a chronic skin and systemic disease, whose treatment is related to important side effects and loss of life quality. In previous results [1], mice treated with Antimonium crudum (AC) 30cH presented reduction in local inflammatory process and modulation of B1 cell-phagocyte differentiation and migration, but also increase...
The effects of a maternal hypercaloric diet (HD) during puberty and early adulthood on neuroimmune aspects in offspring were investigated. In female rats of the F0 generation and male rats of the F1 generation, bodyweight (BW) gain, retroperitoneal fat (RPF) weight, the number of hypodermic adipocytes (HAs) and expression of glial fibrillary acidic...
Methylphenidate (MPD) is a dopamine uptake inhibitor and the most commonly prescribed drug for the treatment of attention-deficit/hyperactivity disorder in children. Several studies have shown that such stimulants as cocaine and amphetamine that are administered during gestation and lactation may disrupt maternal behavior. Also, MPD is use in lacta...
Background
In previous studies, we observed that thymulin 5cH could modulate BCG (Bacillus Calmette-Guerin) induced chronic inflammation by increasing peritoneal B1 stem cells differentiation into phagocytes and improving phagocytosis efficiency.
Methods
We used the same protocol to study the effects of thymulin 5cH in the experimental murine Leis...
Background
Leishmaniasis is a zoonotic disease caused by protozoan parasites of the mononuclear phagocytic system. The modulation activity of these cells can interfere in the host/parasite relationship and influences the prognosis.
Methods
We evaluated the effects of the homeopathic preparation Antimonium crudum 30cH on experimental infection indu...
4) H&N Homeopatia-Farmácias HNCristiano; (5) Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; (6) Universita' degli studi di Verona, Verona, Italy Zincum metallicum (ZM) is a homeopathic medicine whose material medica is defined by diverse behavioral and mental symptoms, including depression. Moreover, as a microelement, zinc itself...
To evaluate the efficacy of prophylactic homeopathic treatment of swine diarrhea to achieve a satisfactory balance between weight gain and cost. Methods: Escherichia coli (E. coli) was isolated from 4 piglets with diarrhea, their clinical signs were used to select the adequate homeopathic medicine China officinalis (Chin). Newborn piglets were divi...
The present study analyzed the immune modulation mechanisms of thymulin 5CH in a granuloma experimental model. Male adult Balb/c mice were inoculated with BCG into the footpad to induce granuloma, which was quantitatively evaluated. The phenotypic characterization of phagocyte, T- and B-lymphocyte populations in the peritoneum, and local lymph node...
It has been speculated that the homeopathic treatment of sperm cells in order to improve semen quality could be promising. However, few data is available and its use in spermatozoa requires investigation. It is well established that mitochondrial membrane potential is an important viability parameter of spermatozoa and it is intimately related to r...
Escherichia coli has zoonotic potential; it can also contaminate the environment and endanger the hygiene and sanitary qualities of foods produced in contaminated soil ([Murray and others 1999][1], [Gophna and others 2001][2], [Ron 2006][3]). Proper disposal of the carcases of piglets infected by E
Aims: this study sought to assess the reproductive performance of sows inseminated with sperm treated with homeopathic medicines. Materials and methods: the semen of 2 sexually mature boars age 18 months Pietrain and Duroc cross-bred with similar genetic and reproductive performance were chosen, as well as 125 sows. Sixteen samples of semen were co...
RESUMO O objetivo do presente trabalho foi determinar a soroprevalência da leptospirose em fêmeas bovinas em idade reprodutiva no Estado da Bahia. A amostragem foi delineada para a determi-nação da prevalência de propriedades positivas (focos) e de animais soropositivos para a leptospirose. O Estado foi dividido em quatro regiões ou estratos amostr...
Escherichia coli is the most important etiologic agent implied in neonatal diarrhea in swine; colibacillosis is the disease with highest impact in production of swine. The demands of consumers for meat without chemical residues and the ban on the use of antibiotics and chemotherapics in production of swine compelled to find alternative therapeutic...
To evaluate the zootechnic performance and occurrence of diarrhea in piglets in the week post-weaning comparing supplementation with sucrose saline which contained or did not contain added homeopathic medicine.
Animals were randomly divided into three groups of 24 piglets each. The control group did not receive any treatment. Another group received...
The behavioral and hematological effects of treatment with Chamomilla 6cH in mice subjected to experimental stress are described. Swiss mice were randomly divided into pairs, one animal was inoculated with Ehrlich's tumor, the other was treated daily with Chamomilla 6cH or control or received no treatment. After 7 days, the animals were observed in...
The therapeutic and pathogenetic effects of Dolichos pruriens were evaluated using experimental models in rats. In the therapeutic experiment Wistar rats were housed in a heated environment (25+/-3 degrees C) to induce itch, and treated with ascending potencies D. pruriens (6 cH, 9 cH, 12 cH and 30 cH), each for 10 days. The positive control group...
Os efeitos terapêuticos e patogenéticos do Dolichos pruriens foram avaliados usando modelos experimentais bem estabelecidos pela farmacologia tradicional para avaliar parâmetros comportamentais, através de métodos “Campo aberto” e “Grooming”. O objetivo desse estudo foi testar se os modelos experimentais propostos eram instrumentos adequados para:...
This study was performed during two years, in a commercial swine herd, located at the municipality of Ibiúna, São Paulo State and had the objective of setting the prophylaxis and treatment of swine at the nursery room and at the fattening stage, using homeopathic
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