Chung Keat Tan

Chung Keat Tan
UCSI University | ucsi · Faculty of Medicine and Health Sciences

PhD (Biochemistry)

About

41
Publications
7,876
Reads
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106
Citations
Additional affiliations
May 2009 - July 2012
Universiti Kebangsaan Malaysia
Position
  • Research Assistant

Publications

Publications (41)
Article
Full-text available
Monotherapy for triple-negative breast cancer (TNBC) is often ineffective. This study aimed to investigate the effect of calcitriol and talazoparib combination on cell proliferation, migration, apoptosis and cell cycle in TNBC cell lines. Monotherapies and their combination were studied for (i.) antiproliferative effect (using real-time cell analyz...
Article
Excessive salt consumption has been associated with greater risk of hypertension. Therefore, monitoring of dietary sodium consumption should be prioritized. As sodium is mainly excreted through urine, 24‐hours urine sample can be used to estimate individual sodium intake. Thus, a simple and inexpensive semi‐quantitative urinary sodium detection tes...
Article
Full-text available
Ceramides plays a crucial role in maintaining skin barrier function. Although foregoing evidence supported beneficial effects of topical ceramides for restoration of the skin barrier, studies on oral ceramides are extremely scarce, with most published data collected from in vivo and in vitro models. Thus, this study aimed to evaluate the efficacy o...
Article
Full-text available
Ambient air pollution is a significant contributor to disease burden, leading to an estimated 4.2 million premature deaths and 103.1 million disability-adjusted life years (DALYs) annually worldwide. As industrialization and urbanization surge in Asia, air pollution and its corresponding health issues follow suit. Findings on disease burden in deve...
Conference Paper
Full-text available
Periorbital hyperpigmentation (POH) is defined as bilateral, round, homogenous pigment macules on the infraorbital regions. The condition is more evident in some ethnic groups and is commonly seen in multiple famil\ members. AlWhoXgh iW doesn·W signif\ Xnderl\ing diseases and causes morbidity, POH disrupts emotional well-being b\ decreasing Whe paW...
Conference Paper
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Global disease burden attributable to air pollution has remained a major issue of concern over the years. Epidemiological findings on air pollution adverse effects to human respiratory and skin however remain limited with regards to disease burden assessment in Malaysian. Thus, this study aimed to compare association of ambient air PM2.5 concentrat...
Article
Full-text available
Indonesia is the third largest user of mobile phone (MP) in Asia Pacific Region in 2019. The vast development of MP has made it an inseparable component of everyone's life and yet little is known about its potential harmful effects. Therefore, this study aimed to assess the pattern of MP use among adults in Indonesia and its association with Headac...
Conference Paper
Full-text available
Introduction: Wound infection is a global health concern especially in the tropical regions. It is crucial to ensure none or minimal bacterial growth for speedy recovery as well as to reduce risk of scaring. This research aimed to evaluate antimicrobial effect of plant-based extracts of Quercus infectoria and Acorus calamus in standard bacterial st...
Article
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Tiger milk mushroom (TMM; Lignosus rhinocerus ) have been used for a long time by indigenous communities in South East Asia regions as traditional medicine for different ailments, including respiratory disorders. The beneficial effects of TMM have been proven through in vivo and in vitro models, but these effects have yet to be validated in a clini...
Conference Paper
Full-text available
Introduction: Adverse health effects due to air pollution have become a major global public health concern over the decades. Epidemiological studies are suggestive of PM2.5’s adverse effect on human skin; however, the findings remain limited. This study aims to compare the association of ambient air PM2.5 with skin dryness and itchiness among indoo...
Article
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In Malaysia, chronic respiratory disease including COPD is responsible for 7% of the total Disability-Adjusted Life Years (DALYs). Sleep disturbance in COPD patients is often underestimated and overlooked clinically. Respiratory symptoms caused by COPD often leads to poor sleep quality and insomnia. Poor sleep quality contributes to frequent episod...
Article
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Treatment for abnormal melanin accumulation is available with controversial results, thus aim of the present work was to determine azelaic acid (AZ) and glycolic acid (GLY) cytotoxicity and inhibiting melanogenesis efficacy. Safety concentration and efficacy in reducing the melanin content were access through MTT assay, Fontana-Masson staining, mel...
Article
Full-text available
Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treatment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpar-tum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of nourishing blood and resolving stasis. Concerns...
Article
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Treatment and management of wounds is largely dependent on the dressing material which, in addition to providing surface protection, drug delivery and bacteriostatic activities, also allows cell and tissue regeneration. Subsequently, scientists developed mechanisms to promote cell propagation in the wound and accelerate the healing process. However...
Article
Full-text available
Introduction: Acne vulgaris is a chronic inflammatory dermatosis caused by Propionibacterium acnes. Clinicians are constantly attempting to discover the best antibiotic regimes in treating acne vulgaris. This study compares two regimens in terms of efficacy, tolerability, compliance and recurrence rate to make recommendation on which is the best re...
Article
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Introduction: In Malaysia, herbal medicines are used for variety of reasons including health promotion and home remedies during pregnancy and postpartum with Manjakani (Quercus infectoria) as one of the most commonly consumed herbs. Herbal medicines consumption had been linked to heavy metals contamination and transfer from mother to infant and may...
Article
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Introduction: Periorbital hyperpigmentation (POH) is among the commonest esthetic and dermatological complaints. Despite its frequency, there are inadequate information detailing its incidence and prevalence. This subsequently leads to lack of comprehensive POH classification and stratification of impact on an individual's general well'being. Mala...
Article
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Stem cell research and treatment hold much promise and expectation both globally and locally to date with a lot of interest garnered. The aim of this survey was to assess their knowledge, awareness and perception towards stem cells based on their employement level, as well as insight on healthcare personnel‘s acceptance of stem cells from religious...
Article
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Chronic diseases are rising in number and have become the leading cause of mortality in the world. These diseases can be controlled via diet and lifestyle modifications. Nutrigenomics recently emerge as a study area endeavoring to understand one’s response to diet at molecular level. Despite its rapid development, limited number of health care work...
Article
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Androgenic alopecia (AGA) is a common hair loss disease with genetic predisposition among men and women. AGA may start any age after puberty and is affecting one’s social aspects as well as significantly impacted psychological and overall of quality of life. Medically, AGA is considered a mild dermalogical illness. However, those suffering from the...
Article
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Menopause is a physiologic phase in women life involving hormonal changes that could lead to severe menopausal symptoms and thereafter affecting one’s quality of life. Moreover, army wives lead stressful lives. In this study, we aimed to determine quality of life among army wives during menopausal transition as well as to investigate possible assoc...
Article
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Regenerative Medicine (RM) is an interdisciplinary field with countless potentials and serves as a solution for the growing rate chronic diseases, communicable and non-communicable diseases in developing countries. For the past 23 years, Malaysia has been exploring this field for the boon RM holds.This study aimed to determine the level of knowledg...
Article
Full-text available
All around, natural medication is an undeniably sought after elective drug. They had been expended for ages to enhance one’s prosperity. In Malaysia, Malay home grown medications (MHMs) are ordinarily expended amid pregnancy and baby blues by moms of the Malay people group. This investigation is a similar poll consider including 106 baby blues Mala...
Article
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Anti-aging medicine cultivates a target for medical intervention. However, it is still a controversial topic which needs more research to provide a better understanding of safety and efficacy of anti-aging medicine. This study is aimed to evaluate Malaysians’ demand and awareness of anti-aging medicine. A questionnaire with 17 questions in four par...
Article
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Literature has documented that student nurses undergo stress in their academic and clinical setting. This raises concerns because stress during undergraduate training may result in psychological or emotional impairment during the nurses' professional life and ultimately affect the quality of patient care. The Objective of the study was to study the...
Article
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Background and objectives: Acne vulgaris is a common skin condition among adolescents and young adults. Its relationship with the dietary intake is highly debatable and equivocal. This study aimed to identify the association between acne vulgaris and dietary intake among Malaysians. Methods and study design: A case-control study was conducted in...
Article
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Introdução: A identificação das causas da hipercromia cutânea idiopática da região orbital (HCIRO) é fundamental para o processo de seleção da melhor conduta terapêutica. Objetivo: O presente estudo tem como objetivo avaliar as alterações histopatológicas de diferentes tipos de HCIRO. Métodos: Quarenta e nove voluntários saudáveis foram classificad...
Article
Full-text available
Androgenic or androgenetic alopecia is a very frequent cause of hair loss affecting males over 50 years of age. For ages, wearing a cap which covers the frontal, parietal and upper parts of temporal and occipital areas of the scalp is commonly employed as a tradition in males. These areas coincide with the affected area in androgenic alopecia. Henc...
Conference Paper
Full-text available
Stem cells have an amazing potential in the treatment of various health-related condition due to their ability to self-renew and having high potency to differentiate into multiple cell lineages. Unfortunately, in Malaysia, stem cell research and treatments are relatively at early stage even among the healthcare personnel. Therefore, the aim of this...
Article
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There is increased interest in the consumption of hot pepper (Capsicum annuum cv. Kulai) due to its high antioxidant content; however, pepper is also highly susceptible to postharvest losses. The goal of this study was to evaluate the combined effect of 1-methylcyclopropene (1-MCP) and modified-atmosphere packaging (MAP) compared to MAP alone in ma...
Article
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The objective of the present study was to simultaneously evaluate the effect of a postharvest treatment on the pepper's antioxidant content and its ability to retain its economical value during the postharvest period. The fruits were pretreated by modified atmosphere packaging (MAP) with or without treatment with 1-methylcyclopropene (1-MCP) before...
Article
The aim of the present study was to evaluate the changes in ethylene production, carbohydrase activities and antioxidant status in pepper Kulai at different ripening stages. This cultivar of pepper fruits exhibits a peak in ethylene production during stage 3 of ripening. The production of 1-aminocyclopropane-1-carboxylic acid (ACC) and ACC oxidase...

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Question (1)
Question
Any public health journal with IF 0.3-1, and fast processing time to recommend? thank you.

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