Chukwuanugo N Ogbuagu

Nnamdi Azikiwe University | Unizik · Medical Microbiology and Parasitology

Background: Cognitive assessment is a key component of clinical evaluations for patients with dementia and Alzheimer's disease in primary health care (PHC) settings. The need for well-validated, culturally appropriate, and easy-to-use assessments is especially urgent in low- and middle-income countries (LMICs) that are experiencing rapid growth in...

Objective The aging population in developing countries demands parallel improvements in brain health assessment services to mitigate stigma, promote healthy aging, and diagnose cognitive impairments including dementia in primary health care (PHC) facilities. The lack of culturally appropriate cognitive assessment tools in PHC facilities delays earl...

Brain health refers to the state of a person’s brain function across various domains, including cognitive, behavioral and motor functions. Healthy brains are associated with better individual health, increased creativity, and enhanced productivity. A person’s brain health is intricately connected to personal, social and environmental factors. Racia...

Objectives This study aimed to evaluate the microbiological quality of water sources in Ishaka division, Bushenyi district. Methods Water from taps, wells and springs were sampled for the cross-sectional investigation. The enumeration and identification of microbes (Escherichia coli, Salmonella, Shigella, Proteus, Staphylococcus aureus and total c...

Objectives The study determined the rate of recent and past Toxoplasma gondii infections, associated factors, and awareness among expectant mothers assessing antenatal care in a tertiary hospital in Nigeria. Methods This prospective cohort study was conducted among pregnant women. A questionnaire was used to gather information on socio-demographic...

Objectives Primary health care remains the widely available first point of medical care in Nigeria and in other low- and middle-income countries. Recognizing the rising prevalence of dementia in these settings, primary healthcare providers should be trained on cognitive assessment. However, little is known about the current Nigerian primary healthc...

Synovial sarcomas primarily occur in soft tissues close to the joints and extremities. When they arise close to the hallucal sesamoids, which play a role in the static and dynamic weight process of the foot, present a management dilemma. We report a case of a soft tissue synovial sarcoma of the foot in a previously fit and healthy 17-year-old indiv...

Objective: We systematically identified the prevalence of triplex infections (combined human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV)) in pregnancy. Methods: To gather information on the frequency of triplex infections, we searched the databases of PubMed, CINAHL, and Google Scholar. Without regard to la...

Objectives Routine dipstick urinalysis is a useful and inexpensive method for the early detection of asymptomatic diseases. Our study was carried out to detect the prevalence of urinary abnormalities among an apparently asymptomatic healthy female group and emphasize the value of routine dipstick urinalysis. Methods A cross-sectional study was car...

Objectives: To systematically review literature and identify mother-to-child transmission rates of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among pregnant women with single, dual, or triplex infections of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus in Nigeria. PRISMA guidelines were employ...

Background: Antiretroviral therapy (ART) has significantly increased the lifespan of people living with HIV. Currently, fixed dosed combination therapy (Tenofovir, Lamivudine, and Dolutegravir) is being introduced in most countries in the Sub- Saharan Africa. There is need for a clinical and immunological assessment of HIV patients transitioned to...

Background: Antiretroviral therapy (ART) has significantly increased the lifespan of people living with HIV. Currently, fixed dosed combination therapy (Tenofovir, Lamivudine, and Dolutegravir) is being introduced in most countries in the Sub- Saharan Africa. There is need for a clinical and immunological assessment of HIV patients transitioned to...

Hepatitis B virus Infection is a chronic Infection with increasing incidence and worldwide prevalence. It is a leading cause of liver failure and hepatocellular carcinoma. Healthcare personal, chronic blood transfusion, unprotected sex, etc are some major risk factor of contracting the disease. It can be prevented by vaccination. This study was car...

Objective: To determine the hepatitis B vaccination coverage, full-dose (⩾3) coverage and the associated factors affecting uptake among pregnant women. Methods: This was a cross-sectional study among pregnant women attending antenatal care in six tertiary hospitals across all the geopolitical zones of Nigeria. Pregnant women who consented to the...

Background: There are no national data on hepatitis C virus awareness and burden among pregnant women to justify its routine screening. Objectives: To investigate awareness, seroprevalence and risk factors for hepatitis C virus infection among pregnant women in Nigeria. Methods: A total of 159 pregnant women from antenatal clinics across six geopol...

Background There are no national data on hepatitis C virus awareness and burden among pregnant women to justify its routine screening. Objectives To investigate awareness, seroprevalence and risk factors for hepatitis C virus infection among pregnant women in Nigeria. Methods A total of 159 pregnant women from antenatal clinics across six geopoli...

Objectives: To determine the adolescents’ views of sexually transmitted diseases preventive measures. Methods: This was a cross-sectional descriptive study of 310 adolescents in Atani, Nigeria. All unmarried sexually active adolescent living in the community was included in the study while all married and menopausal non sexually active adolescent...

The study investigated the perception of Lassa fever among civil servants in Awka Nigeria: The factorial impact of age, gender and educational level. The purpose of the study is to find the differences between gender, educational level, and age on the perception of Lassa fever among civil servants in Awka metropolis. The population of the study com...

Background: Although hepatitis C virus (HCV) may constitute one of the viral hepatitis with high burden in Nigeria, there is no national data on its awareness and burden among pregnant women to justify its routine screening. Objectives: To investigate awareness, seroprevalence and risk factors for HCV infection among pregnant women in Nigeria. Meth...

The outbreak of coronavirus disease has been declared a public health emergency of international concern and the virus has spread to many countries and territories. The objective of this study is to assess the knowledge and level of awareness of covid-19 pandemic among traders, To know their perception of covid-19 symptoms, To know if they actually...

The survey on the ecology of man-biting mosquitoes in Nnewi was undertaken between April and June 2019. Larval stages of mosquitoes were sampled from gutters, used discarded tyres, plastic containers, water pots, clean ground water pools, plantain and banana plants axils and dirty ground water pools using ladle, sieves and bowels. Indoor biting and...

The dietary pattern in any population is an indicator for the general well-being and the extent of their risks to have lifestyle disorders. These include diabetes mellitus, dyslipidaemia, hypertension and coronary heart disease, which are the main cause of death worldwide. Medical students; representing part of the young age population of the commu...

Background: Nigeria contributes significantly to the global burden of HIV, Hepatitis B and C infections, either singly or in combinations, despite progress in HIV care regionally and globally. Although some limited data on mono infection of HIV, Hepatitis B and C virus infections do exists, that of dual and triplex infections, including seroconvers...

Background: Water is essential for life and accounts for about 70 percent of the human body fat-free mass. Daily loss of 2.5 L in temperate climate occurs on least minimal activity while exercises, rises in temperature, illnesses raise the fluid loss. Adequate intake of water is necessary for optimal body functions, development and health. Estimate...

Background: The novel coronavirus disease outbreak has halted activities throughout the globe because of its rapid spread. Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) a β-coronavirus first detected in China. SARS-CoV-2 has been implicated to be transmitted via direct contact, fomite, resp...

Background Buruli ulcer is one of the neglected tropical diseases. It is a chronic, debilitating, necrotising disease of the skin and soft tissue caused by Mycobacterium ulcerans . Most times, the pattern of presentation is neglected by the infected because it is regarded as a disease of the poor who have little or no access to healthcare. Living i...

Abstract Objectives: To determine the incidence and severity of adverse drug reactions among hospitalized patients in a Nigerian teaching hospital using the trigger tool method. Study Design: Descriptive cross-sectional study. Setting: The study was conducted in Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria from July to December, 2012...

This study determined patterns of microbial isolates in genital tract of women with preterm pre-labour rupture of membranes (PPROM) compared with cases without PPROM. Endocervical swabs of women with confirmed diagnosis of PPROM were examined microbiologically and compared in blinded pattern with gestational-age-matched controls. One hundred and fi...

Objective To identify microbes prevalent in the genital tract of pregnant women with preterm premature rupture of membranes (PPROM) and to assess the susceptibility of the microbial isolates to a range of antibiotics to determine appropriate antibiotics for treating cases of PPROM in resource-limited settings. Methods A prospective cross-sectional...

Background TB and HIV co-epidemic is a major public health problem in many parts of the world, particularly in developing counties. This study was a prospective cohort design to determine the seroprevalence of HIV infection among tuberculosis patients attending TB/Directly Observed Treatment Short-course (DOTS) centre in a tertiary hospital in Nnew...

A study on malaria prevalence and use of Insecticide-treated nets (ITN) was carried out in Aguleri community of Anambra State from October 2011-March 2012. A two stage cluster sampling technique was used to select three villages and the individuals used for the study. Giemsa stained thick and thin blood samples of 327 individuals were examined micr...

A study on malaria prevalence and use of Insecticide-treated nets (ITN) was carried out in Aguleri community of Anambra State from October 2011-March 2012. A two stage cluster sampling technique was used to select three villages and the individuals used for the study. Giemsa stained thick and thin blood samples of 327 individuals were examined micr...

Hepatitis B virus (HBV) infection in Nigeria has remained a Public Health issue. It is a major cause of mortality, especially in developing countries. Vertical transmission of hepatitis B virus infection is thought to be a major route of transmission in low resource areas. In spite of this, routine antenatal screening for hepatitis B infection is n...

Objective: This study aimed at investigating the cases of Undiagnosed Human Immunodeficiency Virus (HIV) amongst patients attending the Accident and Emergency (A&E) Unit of Nnamdi Azikiwe University Teaching Hospital (NAUTH) to determine the prevalence and individual awareness of their sero-status. Method:Human Immunodeficiency Virus (HIV) 1 and 2...

260 stool samples were randomly collected from pupils in four primary schools in Ozubulu, Anambra State. The samples were collected from pupils of both sexes whose ages ranged from 5-16 years old. Using formol- ether concentration method, the stool samples were processed. Questionnaires were also distributed to check for relationship between infect...

Background: Traumatic brain injury is a major public health problem in Nigeria, as it could be associated with long term and life long deficits. Unlike other parts of the world, in our country, motorcycles are possibly the main cause of this injury. Unfortunately, we do not have a national epidemiological data base yet. This study was aimed at defi...

Objective To determine the pattern of neurosurgical diseases presenting to a tertiary health institution in Nigeria, 30 months after the commencement of services, in order to establish the local demographic data base and subsequently, structure service delivery on the evidence-based disease profile. Methodology A retrospective study using the ad...