Christos Kotsalos

Christos Kotsalos
University of Geneva | UNIGE · Department of Computer Science

About

16
Publications
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202
Citations

Publications

Publications (16)
Preprint
Recent advances in computational neuroscience have demonstrated the usefulness and importance of stochastic, spatial reaction-diffusion simulations. However, ever increasing model complexity renders traditional serial solvers, as well as naive parallel implementations, inadequate. This paper introduces a new generation of the STochastic Engine for...
Article
Full-text available
Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet activation or the molecular dynamics involved in platelet interactions and are incapable to consider inter-indiv...
Article
Full-text available
Palabos-npFEM is a computational framework for the simulation of blood flow with fully resolved constituents. The software resolves the trajectories and deformed state of blood cells, such as red blood cells and platelets, and the complex interaction between them. The tool combines the lattice Boltzmann solver Palabos for the simulation of blood pl...
Article
Full-text available
We propose a highly versatile computational framework for the simulation of cellular blood flow focusing on extreme performance without compromising accuracy or complexity. The tool couples the lattice Boltzmann solver Palabos for the simulation of blood plasma, a novel finite-element method (FEM) solver for the resolution of deformable blood cells...
Preprint
Full-text available
Palabos-npFEM is a computational framework for the simulation of blood flow with fully resolved constituents. The software resolves the trajectories and deformed state of blood cells, such as red blood cells and platelets, and the complex interaction between them. The tool combines the lattice Boltzmann solver Palabos for the simulation of blood pl...
Preprint
Full-text available
Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present clinical tests to detect CVD are ineffectual as they do not consider different stages of platelet activation or the molecular dynamics involved in platelet interactions and are incapable to consider inter-indivi...
Article
Red blood cells (RBCs) in pathological situations undergo biochemical and conformational changes, leading to alterations in rheology involved in cardiovascular events. The shape of RBCs in volunteers and stable and exacerbated chronic obstructive pulmonary disease (COPD) patients was analyzed. The effects of RBC spherization on platelet transport (...
Preprint
Full-text available
The transport of platelets in blood is commonly assumed to obey an advection-diffusion equation. Here we propose a disruptive view, by showing that the random part of their velocity is governed by a fat-tailed probability distribution, usually referred to as a L\'evy flight. Although for small spatio-temporal scales, it is hard to distinguish it fr...
Preprint
Full-text available
Rationale: There are important interactions between Red Blood Cells (RBCs) and platelets in the bloodstream. These interactions lead to a phenomenon called margination. RBCs in pathological situations undergo biochemical and conformational changes leading to alterations in blood rheology. Aim: RBCs shape in volunteers (21), stable (42) and exacerba...
Article
Full-text available
We present the scope, concepts, data structures and application programming models of the open-source Lattice Boltzmann library Palabos. Palabos is a C++ software platform developed since 2010 for Computational Fluid Dynamics simulations and Lattice Boltzmann modeling, which specifically targets applications with complex, coupled physics. The softw...
Preprint
Full-text available
We propose a highly versatile computational framework for the simulation of cellular blood flow focusing on extreme performance without compromising accuracy or complexity. The tool couples the lattice Boltzmann solver Palabos for the simulation of the blood plasma, a novel finite element method (FEM) solver for the resolution of the deformable blo...
Preprint
Full-text available
We present the scope, concepts, data structures and application programming models of the open-source Lattice Boltzmann library Palabos. Palabos is a C++ software platform developed since 2010 for Computational Fluid Dynamics simulations and Lattice Boltzmann modeling, which specifically targets applications with complex, coupled physics. The softw...
Article
We present a computational framework for the simulation of blood flow with fully resolved red blood cells (RBCs) using a modular approach that consists of a lattice Boltzmann solver for the blood plasma, a novel finite element based solver for the deformable bodies and an immersed boundary method for the fluid-solid interaction. For the RBCs, we pr...
Preprint
Full-text available
We present a computational framework for the simulation of blood flow with fully resolved red blood cells (RBCs) using a modular approach that consists of a lattice Boltzmann solver for the blood plasma, a novel finite element based solver for the deformable bodies and an immersed boundary method for the fluid-solid interaction. For the RBCs, we pr...
Poster
Full-text available
It is well established experimentally that as the Reynolds number increases the core of the jet diminishes and has smaller effects on the jet’s mean profiles (e.g. concentration, temperature, velocity). The scope of this project is to examine this relationship based on dimensional analysis and experimental data. For that, spatio-temporal temperatur...

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Project (1)
Project
Palabos is an open-source software for Lattice Boltzmann simulations. This page gathers relevant articles and announcements. For further information, please visite the Web site (https://palabos.unige.ch) or the Forum (https://palabos-forum.unige.ch/).