Christopher Ekpenyong

Christopher Ekpenyong
University of Uyo | UNIUYO · Department of Physiology

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65
Publications
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1,406
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Publications

Publications (65)
Article
Epilepsy is one of the chronic neurological conditions affecting people of all ages globally. Educational progress have been affected negatively by some abnormalities associated with epilepsy. This study employed neurobehavioural analysis of pentylenetetrazole (PTZ) induced seizure on some visual spatial functions in Wistar rats. The study was done...
Article
Background: Recently, we have witnessed a surge in the population of Diabetics and of course in the cases of Diabetic Foot Syndrome(DFS) requiring amputation. However, accepting amputation is difficult for patients and this has become a family or community decision to undergo amputation despite being a lifesaving procedure in most cases. Some patie...
Article
Background: Despite available evidences that pregnant women are specific vulnerable target population for dehydration and the importance of adequate hydration to both the mother and the developing fetus, studies assessing the prevalence and associated risk factors of dehydration among pregnant women are limited. Aim: The aim of the present study wa...
Article
Background: The prevalence of childhood obesity (COB) in the developing world is currently high and is rising rapidly. Unlike developed countries, studies evaluating the association between parental socio-economic status (SES) and risk of COB in developing countries are limited. Besides, the association varies across country and race/ethnicity and...
Article
Background: Although several factors are known to influence the gestational age at booking, current knowledge indicates that the distribution of these factors could vary from one country to the other, and even within countries, the variation could exist between states. This study aimed to assess the prevalence, predictors and clinical correlates of...
Article
Background: Existing data indicate that poor hydration status adversely affects academic performance and health status of college students, but hydration studies among students have not received sufficient research and educational attention. The aim of this study was to determine the prevalence and associated risk factors of dehydration among colle...
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Full-text available
The impact of health and environmental hazards, associated with the constituents of gasoline, on occupationally exposed workers has been recorded over the past few decades. However, the scientific literature on their pathogenic potential remains incomplete, which could affect the current understanding of the associated health risks. This review pro...
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Full-text available
Deficiencies of minerals and trace elements are common and widespread, and are associated with adverse cardiovascular endpoints. Emerging evidence indicates that, diet rich in these nutrients constitutes a modifiable lifestyle factor that might reduce the risk of cardiovascular disease (CVD). However, the clinical significance of these nutrients in...
Article
Background: Gasoline is a mixture of several hydrocarbons and additives and is associated with numerous adverse health effects including renal function impairment. The aim of this study was to evaluate the ameliorative effect of Cymbopogon citratus on gasoline vapour-induced renal function impairment. Methods: Seventy-two mature female Wistar albin...
Article
The economic burdens and health implications of food spoilage are increasing. Contamination of food sources by fungi, bacteria, yeast, nematodes, insects, and rodents remains a major public health concern. Research has focused on developing safer natural products and innovations to meet consumers' acceptance as alternatives to synthetic food preser...
Article
Cymbopogon citratus is a widely distributed perennial herb belonging to the Poaceae family and has been extensively consumed for its medicinal, cosmetic, and nutritional effects for centuries. A large number of reports have been published describing the pharmacological, biological, and therapeutic actions of this herb. In this review, we summarized...
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Full-text available
Dicliptera verticillata (Forssk) Ch. (Acanthaceae) (leaf) is used as a traditional medicine for the treatment of malaria and diarrhoea in Burkina Faso and among the Ibibios of southern Nigeria. This study was aimed at evaluating the antiplasmodial activities of the ethanol leaf extract of Dicliptera verticillata in Plasmodium berghei infected mice...
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Diet plays an important role in the pathogenesis of abnormal serum uric acid (UA) levels and associated complications. Diet modification has been universally adopted as an important and early intervention approach to reduce or increase UA production and/or enhance or inhibit UA excretion. This article reviews the literature on the effects of diets...
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Full-text available
Background: The plant Nauclea latifolia is widely used in the southern parts of Nigeria for the treatment of malaria. Malaria is the number one killer disease in Nigeria. WHO reports that malaria continues to cause approximately 207 million cases of infection around the world and kills yearly about 627,000 people. It still kills a child somewhere i...
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The existing research findings regarding the effects of lemongrass (Cymbopogon citratus) tea on renal function indices are conflicting and inconclusive. In the present study, we investigated the effects of infusions prepared from C citratus leaves on creatinine clearance rate (CCr) and estimated glomerular filtration rate (eGFR) in humans. One hund...
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Objective: This study assessed the association between worker characteristics, workplace factors, and work-related musculoskeletal disorders (WMSDs) in Nigeria's construction industry. Methods: A cross-sectional site-by-site survey was conducted in 5 existing construction companies in Uyo, Nigeria. The subjects (n = 1200 males), aged 18-55 years...
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Full-text available
Objective: To assess the diuretic activity of infusions prepared from Cymbopogon citratus (C. citratus) leaves in healthy volunteers. Methods: One hundred and five subjects (55 men and 50 women) aged 18 to 35 years were randomly assigned to groups set to orally receive infusions prepared from 2, 4, or 8 g of C. citratus leaf powder, once daily for...
Article
Abstract This study assessed the effects of lemongrass (Cymbopogon citratus) tea on hematologic indices in human volunteers. One hundred five subjects (55 men and 50 women), aged 18 to 35 years, were randomly assigned to groups set to orally receive infusion prepared from 2, 4, or 8 g of C. citratus leaves once daily for 30 days. Assessment of hema...
Article
Several health belief models suggest that health risk perception could enhance behavioral modification to reduce lifestyle-related risks. Perceived health risks associated with vaginal douching (VD), propensity to douche and effects on douching behaviors were assessed in a cross-sectional survey of 1,463 female undergraduates, aged 18 to 35 years,...
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Full-text available
Diabetes Mellitus (DM) has been observed to cause altered acid secretion and increase risk of gastric ulceration. This study was therefore designed to investigate the effect of DM on ulcerogenic parameters and to ascertain the impact of treatment with crude Aloe vera gel on same. Twenty male albino Wistar rats weighing 180 - 200 g were randomly ass...
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Thermoxidized palm oil has been shown to generate free radicals in the body, and constitute a major risk factor for developing varying degree of disorders. Following the widely celebrated medicinal uses of Aloe vera gel, this study therefore seeks to examine the effects of its administration on various haematological parameters of rats chronically...
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The adverse health effects of stress are enormous, and vary among people, probably because of differences in how stress is appraised and the strategies individuals use to cope with it. This study assessed the association between academic stress and musculoskeletal disorders (MSDs) among 1365 undergraduates. This was a cross-sectional study conducte...
Article
The growing trend of obesity worldwide and in sub-Saharan Africa can be linked to theurbanization drift experienced in recent years both in developed and developing countrieslike Nigeria, at four pivotal points namely: physical activity level, socio-economic status(SES), nutritional and psychosocial factors. Literature search was done usingMedline/...
Article
Objective: This study assessed the association between ethnicity and family socioeconomic status (SES) as it relates to the prevalence of vaginal douching among female undergraduates in a university community. Participants and methods: This was a cross-sectional survey conducted between September 2011 and February 2012 among 1,535 female undergr...
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Full-text available
Today, the World Health Organization warns that the greater future burden of obesity and diabetes will affect developing countries with the extent doubling with urbanization. Aside from the estimation that, currently, more than 1.6 billion (age 15+ years) adults are overweight and at least 400 million of them are obese, it was also estimated that o...
Article
This work was carried out to study the association between lifestyle, health-care practices and incidence of recurrent vulvovaginal candidosis (RVVC) among young women in south eastern Nigeria. It was a multicentre case-control study of 176 women aged between 20 and 35 years recruited from the designated health facilities. Lifestyle and health-care...
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To assess the respiratory health effect of city ambient air pollutants on transit and non-transit workers and compare such effects by transportation mode, occupational exposure and sociodemographic characteristics of participants. Cross-sectional, randomised survey. A two primary healthcare centre survey in 2009/2010 in Uyo metropolis, South-South...
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This study was aimed to assess the age and sex specific burden and associated risk factors ofNCDs in adult population of South-South Nigeria. It was a cross-sectional study conducted inUyo Metropolis, in 2009/2010; with 2780 participants (1447 males and 1333 females) aged 18-60years. Instruments of survey were: a semi-structured questionnaire, anth...
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The effects of oral administration of aqueous leaf extract of Ocimum gratissimum (OG) on food, water intake and weight changes in streptozotocin (STZ)-induced diabetic Albino Wistar rats was studied. Eighteen rats were randomly assigned into 3 groups of 6 rats each for control, diabetic (DM) and diabetic-treated (DMT) groups. Diabetes mellitus was...
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The aim of this study was to determine the association between academic stress and menstrual disorders among female undergraduates in Uyo, South Eastern Nigeria. Three hundred and ninety-three (393) female students of the University of Uyo, ages between 16 and 35 years were randomly selected from different departments in the University, and studied...
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The purpose of this work was to determine the age and sex specific prevalence of type 2 diabetes mellitus (T2DM) in South Eastern Nigeria, which hitherto has not been documented. The study population consisted of 3500 civil servants, 1532 (43.8%) male and 1968 (56.2%) female, age range 18-60 years. They were randomly selected and studied between Oc...
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This cross sectional study aimed at investigating the effect of tight fitting underwears on the incidence of vulvovaginal candidiasis among non-pregnant women between aged 16 to 35 years. The study took place in seven health institutions between January and July 2009 in Uyo Metropolis, Nigeria. About 191(76.4%) of the 250 participants who were sele...
Article
Ocimum gratissimum (Linn.) has been widely used for food and medicinal purposes. The effect of aqueous leaf extract of O. gratissimum on haematological parameters of albino Wistar rats was studied. Acute toxicity study showed a median lethal dose (LD 50) value of 2121.32 mg/kg body weight for intraperitoneal (i. p) route in mice. Twenty rats' weigh...

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