Christophe Hano

Christophe Hano
Eure et Loir Campus · Phytochemistry

Ph.D
Phytochemistry & Plant Biological Chemistry

About

305
Publications
115,963
Reads
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4,371
Citations
Citations since 2016
265 Research Items
4005 Citations
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Introduction
① Eure & Loir Campus (Chartres) ② Main areas of expertise: Phytochemistry, Plant Metabolism & Plant Biotechnology. ③ PI of several projects including the European Le Studium® Consortium on bioactive extracts for cosmetic applications using plant cell in vitro cultures ④ Associate Editor: PCTOC, Academic Editor: PLOS ONE, Editor: Biomolecules, Cosmetics, Frontiers Plant Science (Plant Metabolism & Chemodiverity), Frontiers Pharmacology (Ethnopharmacology)…
Additional affiliations
September 2006 - present
French National Institute for Agriculture, Food, and Environment (INRAE)
Position
  • Professor (Associate)
September 2002 - April 2022
University of Orleans
Position
  • Professor (Associate)
Education
October 2002 - December 2005
University of Orleans
Field of study
  • Plant Biochemistry / Phytochemistry

Publications

Publications (305)
Chapter
The food industry has recently invested in research to develop new processes that are more respectful to the environment, without sacrificing the quality and safety standards of the final products. The introduction of supercritical fluids (SCFs) in food processing and production has revolutionized different areas of food technology, providing solut...
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Origanum compactum Benth (O. compactum) is widely used traditionally in Morocco to treat a broad range of illnesses, including infectious diseases. The aim of this study was to evaluate the phytochemical composition, quality control, and antibacterial activity of O. compactum leaf and flower essential oil. First, a quality control study on soil and...
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The present work was aimed to study the toxicity of the essential oils of three aromatic and medicinal plants on the tomato leaf miner Tuta absoluta and the Medfly Ceratitis capitata as an alternative to conventional pesticides. We carried out a phytochemical and insecticide study of T. zygis L., S. officinalis L. and M. suaveolens Ehrh. essential...
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Kelussia odoratissima Mozaff. is a medicinal species native to Iran. The goal of this research was to determine the environmental factors important for the distribution of K. doratissima in Iran using BMLR modeling. Six random transects were established throughout the species’ habitat, and 220 quadrats with an area of 4 m2 were plotted. The canopy...
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Cancer has become one of the medical challenges that have left an intolerable death toll around the world. In Morocco, medicinal plants continue to meet a pivotal therapeutic role despite the development of modern sanitation systems. In the current study, an ethnobotanical survey was carried out in the Moroccan national institute of oncology, Rabat...
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Green tea is one of the most popular antioxidant drinks in the world. To make green tea, you must first remove the leaves from Camellia sinensis. A form of tea made from unoxidized green leaves from a tea plantation is called green tea. Several other studies have been undertaken over the past year to evaluate whether consuming green tea and extract...
Article
Traditional herbal medicine is still used for basic healthcare by a significant portion of the population in developing countries. This study aimed to explore the medicinal plant's diversity and to document related traditional knowledge in the Safi region of Morocco. We used semi-structured questionnaires to interview 222 informants living in the s...
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Cotton (Gossypium sp.) is a commercially important annual fibre crop; cottonseed oil (CSO) important product extracted from one of byproducts cottonseeds. Oil yield varies with cotton species, places and season when cotton grown and extraction methods used for oil extraction. This review provides an overview on the extraction of CSO by different ch...
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Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a bioactive compound, a natural anthraquinone aglycone, present mainly in herbaceous species of the families Fabaceae, Polygonaceae and Rhamnaceae, with a physiological role in protection against abiotic stress in vegetative tissues. Emodin is mainly used in traditional Chinese medicine to treat so...
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The most costly spice in the world, Crocus sativus L. (C. sativus), has been used for more than 3,000 years. It has various bene cial applications in a range of elds, including aromas, colorants, and medications, but its usefulness as a food avoring and coloring ingredient is the highest. Large quantities of by-products from the processing of sa ro...
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Anacyclus pyrethrum (L.) (Asteraceae) is an important annual medicinal herb and is widespread in Morocco and Algeria. Most of its parts are used in traditional medicine and the roots are the most important parts used. The present review gives an account of the updated information on its phytochemical and pharmacological properties. We have collecte...
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In today’s scenario, when cancer cases are increasing rapidly, anticancer herbal compounds become imperative. Studies on the molecular mechanisms of action of polyphenols published in specialized databases such as Web of Science, Pubmed/Medline, Google Scholar, and Science Direct were used as sources of information for this review. Natural polyphen...
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Background: Carbohydrate digestive enzymes play a major role in the management of the postprandial hyperglycemia. A chronic hyperglycemia can lead to serious health problems due to excessive production of several reactive oxygen species. Therefore, the inhibition of carbohydrate digestive enzyme and the use of antioxidant natural product can be an...
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Crop domestication usually leads to the narrowing genetic diversity. However, human selection mainly focuses on visible traits, such as yield and plant morphology, with most metabolic changes being invisible to the naked eye. Buckwheat accumulates abundant bioactive substances, making it a dual-purpose crop with excellent nutritional and medical va...
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The present review is designed to measure the effects of saffron extract in functional foods and its pharmacological properties against various disorders. Saffron is a traditional medicinal plant that is being used as food additive. The stigma of saffron has bioactive compounds such as safranal, crocin, crocetin, picrocrocin, kaempferol and flavono...
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Grapevine is one of the most important economic crops in horticulture, and drought stress is one of the most significant threatening factors in the world. Therefore, the identification and investigation of cultivars under drought stress are the basic steps and important goals in grapevine-breeding programs. In the present study, the 17 parameters o...
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Liver and kidney diseases are the most frequently encountered problems around the globe. Damage to the liver and kidney may occur as a result of exposure to various drugs, chemicals, toxins, and pathogens, leading to severe disease conditions such as cirrhosis, fibrosis, hepatitis, acute kidney injury, and liver and renal failure. In this regard, t...
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Honey is a bee product relatively expensive; therefore, it has been a target of adulteration by many sweeteners. In this work, we evaluated the good quality, authenticity, and content in bioactive molecules of twenty-two Moroccan honey from different botanical origins and geographical areas. For that, the following analyses were determined: the con...
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Atriplex halimus L., also known as Mediterranean saltbush, and locally as "Lgtef", an hal-ophytic shrub, is used extensively to treat a wide variety of ailments in Morocco. The present study was undertaken to determine the antioxidant activity and cytotoxicity of the ethanolic extract of A. halimus leaves (AHEE). We first determined the phytochemic...
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Atriplex halimus L., also known as Mediterranean saltbush, and locally as “Lgtef”, an halophytic shrub, is used extensively to treat a wide variety of ailments in Morocco. The present study was undertaken to determine the antioxidant activity and cytotoxicity of the ethanolic extract of A. halimus leaves (AHEE). We first determined the phytochemica...
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Stamen tea from Nelumbo nucifera Gaertn. (or the so-called sacred lotus) is widely consumed, and its flavonoids provide various human health benefits. The method used for tea preparation for consumption, namely the infusion time, may affect the levels of extractable flavonoids, ultimately affecting their biological effects. To date, there is no rep...
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The fabrication of bimetallic nanoparticles (BNPs) using plant extracts is applauded since it is an environmentally and biologically safe method. In this research, Manilkara zapota leaf extract was utilized to bioreduce metal ions for the production of therapeutically important core-shell Au-Ag and hybrid (Au-ZnO and Ag-ZnO) BNPs. The phytochemical...
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Given the effects of salicylic acid (SA) on enhancing the phenolic compounds, flavonoids, and especially anthocyanins at higher doses in grapes as well as some toxic effects of SA at higher doses, the use of nano-carriers and nano-forms could assist SA in enhancing the accumulation of these compounds while reducing its toxic activity. Chitosan (CTS...
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Persimmon is a climacteric perishable fruit with a short storage life. In recent years, using natural compounds that are safe for human health and environment have obtained more attention in postharvest investigations. The current research was conducted to study efficacy of postharvest L-arginine treatment at 0, 0.3, and 0.6 mM in improving chillin...
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Roasting is a key step for preparing sesame oil that leads to important changes in its or-ganoleptic properties and quality. In this study, white sesame seeds were roasted for 20 min in an electric oven at different temperatures (120, 150, 180, 210, 250 and 300 °C). The oils extracted from unroasted and roasted seeds were compared for their chemica...
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Dysphania ambrosioides (L.) Mosyakin and Clemants is a medicinal plant that has traditionally been used to cure a range of diseases. There has been no thorough investigation of the potential toxicity of this plant. The objective of this study is to assess the acute and subacute toxicity of D. ambrosioides hydroethanolic extract (DAHE), as well as i...
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Background The prevalence of obesity around the world arises nowadays in its maximum number. Passiflora sp. genus (Passifloreace family) is native to Brazil and widely cultivated in other regions of America. The extracts of their leaves and fruits have been reported to show sedative and anxiolytic effects. Furthermore, they have been used as a medi...
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Desmodium adscendens (Sw.) DC. is a plant of the Fabaceae family especially rich in flavonoids but also in alkaloids, terpenoids, steroids, phenols, phenylpropanoids, glycosides, and volatiles. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for...
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Solanum virginianum L. (aka Solanum xanthocarpum) is an important therapeutic plant due to the presence of medicinally useful plant-derived compounds. S. virginianum has been shown to have anticancer, antioxidant, antibacterial, antiaging, and anti-inflammatory properties. This plant is becoming endangered due to overexploitation and the loss of it...
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Caryocar coriaceum is an endemic tree of Brazil, occurring mainly in the northeast region in the Cerrado environment. The species, popularly known as "pequi", produces fruits that are used in the manufacture of oil for food and medicinal purposes. This work reviewed studies conducted with the species, highlighting its ethnomedicinal use, its pharma...
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Drought stress is known as a major yield-limiting factor in crop production that threatens food security worldwide. Arbuscular mycorrhizal fungi (AMF) and titanium dioxide (TiO2) have shown to alleviate the effects of drought stress on plants, but information regarding their co-addition to minimize the effects of drought stress on plants is scant....
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Grape canes represent a valuable source of numerous polyphenols with antioxidant properties, whose compositions vary depending on the genotype and environmental factors. Antioxidant activities of pure molecules are often reported without considering possible interactions that may occur in complex polyphenol mixture. Using UPLC-MS-based metabolomics...
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Rivea hypocrateriformis (Desr.) Choisy is a robust woody climbing shrub of the genus Rivea which is widely distributed in India, Nepal, Sri Lanka, Pakistan, Bangladesh, Myanmar, and Thailand. R. hypocrateriformis is a promising medicinal herb with a wide range of beneficial and health-promoting properties. Since the ancient times, it has been used...
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Nanotechnology is an emerging area of research that deals with the production, manipulation , and application of nanoscale materials. Bio-assisted synthesis is of particular interest nowadays , to overcome the limitations associated with the physical and chemical means. The aim of this study was to synthesize ZnO nanoparticles (NPs) for the first t...
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Introduction. Cannabis sativa is a source of oil seeds for pharmaceutical, cosmetic, and food uses. Objective. The aim of this study is to evaluate the hypolipidemic effect of hemp seed oil (HSO) obtained from a local ecotype called “Beldiya.” Methods. The extraction of HSO was carried out by cold press method. Then, the fatty acid and tocopherol c...
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Nymphaea lotus L. is a potential plant in the Nymphaeaceae family that is well-recognized as an economic and traditional medicinal plant in Thailand and other countries. Its pharmacological and medicinal effects have been confirmed. However, there is no study going deeper into the population level to examine the phytochemical variation and biologic...
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The present study examined the effects of foliar spray of selenium nanoparticles (0, 10 and 20 mg/L) on the yield, phytochemicals and essential oil content and composition of pineapple mint (Mentha suaveolens Ehrh.) under salinity stress (0, 30, 60 and 90 mM NaCl). Obtained results demonstrated that severe salinity stress reduced the fresh weight (...
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Use of medicinal plants for the biosynthesis of nanoparticles offers several advantages over other synthesis approaches.
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Plants of the genus Monochoria have long been utilized in food, cosmetics, and traditional herbal treatments. Thailand has the highest species diversity of this genus and a new member, Monochoria angustifolia (G. X. Wang) Boonkerd & Tungmunnithum has been recently described. This plant is called “Siam Violet Pearl” as a common name or “Khimuk Si Mu...
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The present study investigated the antioxidant activity, metal chelating ability and genopro-tective effect of the hydroethanolic extracts of Crocus sativus stigmas (STG), tepals (TPL) and leaves (LV). We evaluated the antioxidant and metal (Fe 2+ and Cu 2+) chelating activities of the stigmas, tepals and leaves of C. sativus. Similarly, we examine...
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Punica granatum is a tree of the Punicaceae family which is widespread all over the world with several types of varieties. Its fruit juice is highly prized, whereas the bark, rich in in phyto-chemicals such as flavonoids, hydrolysable tannins, phenolic acids, and fatty acids, is regarded an agro-industrial waste. It is utilized in traditional medic...
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Ocimum basilicum L. var. purpurascens is an enriched reservoir of pharmaceutically important compounds with plenty of health and therapeutic attributes such as phenolic acids and anthocyanins. However, the inefficient production of aforementioned metabolites in wild has restricted its commercial utilization. Herein, commercially viable phytochemica...
Preprint
Plants of the genus Monochoria have long been utilized in food, cosmetics, and traditional herbal treatment. Thailand has the highest species diversity of this genus and a new member, Monochoria angustifolia (G. X. Wang) Boonkerd & Tungmunnithum has been recently described. This plant is called “Siam Violet Pearl” as a common name or “ไข่มุกสีม่วงแ...
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Full-text available
Dysphania ambrosioides (L.) Mosyakin and Clemants, also known as Mexican tea, and locally known as Mkhinza, is a polymorphic annual and perennial herb, and it is widely used in folk medicine to treat a broad range of illnesses in Morocco. The aim of this study was to determine the phytochemical content and the antioxidant and the antibacterial prop...
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Food processing, especially the juice industry, is an important sector that generate million tons of residues every. Due to the increasing concern about waste generation and the interest in its valorization, the reutilization of by-products generated from the processing of popular fruits of the Prunus genus (rich in high-added value compounds) has...
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With several medicinal and aromatic species, the Asteraceae family is one of the largest angiosperm families. The genus Warionia is represented in this family by only one species, Warionia saharae. In Moroccan traditional medicine, this species is widely used to treat gastrointestinal problems. Essential oil of this plant (EoWs) was studied for pos...
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Preface from the editors to the Plant Cell, Tissue and Organ Culture (PCTOC: Journal of Plant Biotechnology) collection "Secondary Metabolites and Medicinal Plant Biotechnology"
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Background Prunella vulgaris is medicinally important plant containing high-valued chemical metabolites like Prunellin which belong to family Lamiaceae and it is also known as self-heal. In this research, calli culture were exposed to differential ratios of gold (Au) and silver (Ag) nanoparticles (1:1, 1:2, 1:3, 2:1 and 3:1) along with naphthalene...
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Cadmium (Cd) toxicity is a serious environmental issue causing a significant reduction in crop growth and productivity globally. Trehalose (Tre) has emerged as an important reducing sugar that can reduce the adverse impacts of different abiotic stresses. Therefore, the present investigation was performed to determine the key role of Tre in alleviat...
Book
Ginseng is the most well-known Chinese medicine, as well as one of the most commonly used herbal medicines having a wide range of medical and pharmacological uses. The botanical description and complexity of "Ginseng" species, phytochemistry, traditional and biotechnological production systems, traditional usage, current applications, and future di...
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Ginseng saponins, aka ginsenosides, are bioactive phytochemicals from Panax species. Panax comes from the Greek word "panakos," which means "cure-all". Owing to their involvement in the creation of numerous medications and nutritional supplements, ginseng saponins play an essential part especially in the pharmaceutical sector. Assorted preparations...
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Plants have always been the major source of medicinal bioactive substances. Traditional medicine encompasses the use of plants to cure, diagnose, and prevent disease, as well as to preserve health. As seen by the success of antimalaria artemisinin, traditional medicines are a key source of inspiration for so-called modern medicine, which can contri...
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Many plant hormones have been discovered since the Darwins initially proposed auxin activity. Their functions in the modulation of many aspects of plant growth and development (e.g., seed dormancy, seed germination, plant growth, flowering, fruit ripening, etc.) have been extensively studied since then. Plant hormones nowadays include auxins, cytok...
Book
Plant hormones are among the most essential biochemicals found in plants. Since the Darwins identified auxin action, several plant hormones have been discovered. These small signaling molecules regulate not only developmental and growth activities, but also stress response throughout the plant's life cycle. This book, addressed to academics, scient...
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Ginseng preparations have been widely utilized in many traditional medicines, notably Chinese Traditional Medicine, for approximately 5,000 years because of their wide range of medicinal and pharmacological benefits [1]. Ginseng is the generic word for 18 plant species in the Genus Panax (Araliaceae), which means ""all-curing"" in Greek. Panax gins...
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Juniperus turbinata Guss. is a native species of Morocco; however, an exhaustive taxonomic description based on phenotypical characterization of north-eastern Moroccan population species is lacking, which might lead to taxonomic confusion. In order to expound the phenotypic description of J. turbinata of the north-eastern Moroccan population and to...
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Nelumbo nucifera is one of the most valuable medicinal species of the Nelumbonaceae family that has been consumed since the ancient historic period. Its stamen is an indispensable ingredient for many recipes of traditional medicines, and has been proved as a rich source of flavonoids that may provide an antiaging action for pharmaceutical or medici...
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Nelumbo nucifera Gaertn., or the so-called sacred lotus, is a useful aquatic plant in the Nelumbonaceae family that has long been used to prepare teas, traditional medicines as well as foods. Many studies reported on the phytochemicals and biological activities of its leaves and seeds. However, to date, only few studies were conducted on its stamen...