Christine Jacobsen

Christine Jacobsen
University of Zurich | UZH · Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie

M.D., D.M.D.

About

59
Publications
8,043
Reads
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1,069
Citations
Citations since 2016
1 Research Item
609 Citations
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
Additional affiliations
January 2005 - present
University of Zurich
Position
  • Consultant

Publications

Publications (59)
Article
Purpose: Mandibular fractures are amongst the most common facial fractures and are usually treated by open reduction and internal fixation (ORIF). Inferior alveolar nerve (IAN) injuries are seen frequently in mandibular fractures as well as after ORIF of these fractures due to the exposition and the close proximity of the nerve during fracture red...
Article
Purpose: This study aimed to compare the reliability of three different imaging software programs for measuring the PAS and concurrently to investigate the morphological changes in oropharyngeal structures in mandibular prognathic patients before and after orthognathic surgery by using 2D and 3D analysing technique. Material and Methods: The study...
Article
Ameloblastic fibro-odontoma (AFO) is a rare benign tumor which contributes to 1–3% of all odontogenic tumors. AFO is mainly localized in the posterior region of the mandible and typical patients are children who present to their dentists due to non-erupting teeth. We describe an unusual example of a large AFO located in the upper right maxilla and...
Article
Objective: To assess the diagnostic performance of quantitative and qualitative image parameters in cone-beam computed tomography (CBCT) for diagnosis of bisphosphonate-related osteonecrosis of the jaw (BRONJ). Materials and methods: A BRONJ (22 patients, mean age 70.0 years) group was age and gender matched to a healthy control group (22 patien...
Article
Bisphosphonate-related osteonecrosis of the jaw (BONJ) is a common complication of bisphosphonate treatment that has been well documented over the past decade. Nevertheless, its pathogenesis is poorly understood, and treatment guidelines are based mostly on expert recommendations. Clinicians must be aware of malignancy mimicking BONJ, of which a fe...
Article
Differentialdiagnostik ist Detektivarbeit. Leitsymptome führen zu einer Arbeitsdiagnose, die dann mit gezielten diagnostischen Massnahmen zur endgültigen Diagnosestellung führen.
Article
Definition: akute oder chronische Entzündung unterschiedlicher Ursachen der Schleimhaut einer oder mehrerer Nasennebenhöhlen (Sinus maxillaris, ethmoidalis, sphenoidalis und frontalis)
Article
Fusionsdefekte bei der Vereinigung der medialen Nasenwülste, der Oberkieferwülste, des medianen Gaumenfortsatzes, der lateralen Gaumenfortsätze (Gaumenplatten) und des Nasenseptums. Störungen können eine oder beide Entwicklungsregionen total oder partiell, einseitig oder beidseitig betreffen. Dadurch Vielfalt von Spaltformen.
Article
Maligne oder benigne Neubildungen aus epithelialen, ektomesenchymalen oder gemischten (epithelial und ektomesenchymal) Anteilen des zahnbildenden Apparats
Chapter
normale Knochenstruktur durch fibroblasten- und kollagenhaltiges Bindegewebe ersetzt
Article
Full-text available
A 44-year-old man was referred to our department with diplopia, periorbital swelling and haematoma of the left eye after orbital trauma due to a punch. During the examination, mild enophthalmos, hypertropia and a total absence of infraduction were observed. An orbital computed tomography (CT) scan demonstrated a left orbital floor blow-out fracture...
Article
Long-term anthropometric follow-up of cranial vault growth may considerably add valuable information to current literature focusing on treatment strategies for premature multiple-suture craniosynostosis. The aim of this paper was to compare postoperative growth patterns of nonsyndromic and syndromic multiple-suture craniosynostotic children with se...
Article
BACKGROUND: Complex visual hallucinations in the presence of a clear mental state and in the absence of underlying neurological disorders have received increased recognition since Charles Bonnet reported visual hallucinations secondary to mature cataracts in 1760. The prevalence of Charles Bonnet syndrome (CBS) varies widely in the literature and m...
Article
Purpose: This study analysed the aesthetic outcome assessments after trigonocephaly correction using different assessor groups. Methods: Twenty-four patients (9 males, 15 females) with a surgical age between 8 and 10 months were included. Standardised photographs showing different facial views of the patients between ages 3 and 6 years were eval...
Article
BACKGROUND: Bone resorption inhibitor-related osteopathology of the jaw (BRIOJ) is a severe complication in patients treated with bisphosphonates or denosumab. However, the precise pathogenesis of BRIOJ is not yet fully understood. Recent studies discovered the presence of Actinomyces colonies in biopsy material from BRIOJ patients. The aim of this...
Article
Various techniques for the correction of sagittal craniosynostosis have been described in the literature. Nevertheless, there is a lack of consensus regarding surgical procedure and timing, although a long-term anthropometric analysis may shed light on this controversy. The aim of the current study was to collect serial anthropometric data of child...
Article
Fronto-orbital advancement (FOA) is the most common technique used to correct plagiocephaly and trigonocephaly. The aim of this study was to investigate the cranial vault growth following FOA and to compare the growth pattern to the normal standard. Fifty-two Swiss children (25 with anterior plagiocephaly and 27 with trigonocephaly) between the sur...
Article
Background: Metastatic basal cell carcinoma (MBCC) is defined as primary cutaneous basal cell carcinoma (BCC) that spreads to distant sites as histologically similar metastatic deposits of BCC. BCCs are semimalignant, destructive, and invasive. Metastases are very rare, with an incidence of 0.0028%-0.5%. Case report: A female patient with Gorlin...
Article
Antiresorptive therapy is prescribed in particular for the treatment of osteoporosis as well as for the treatment of tumor-induced hypercalcemia and metastatic bone disease. As a con- sequence, osteopathologies such as bisphosphonate-related osteonecrosis of the jaws (BRONJ) may occur. In 2008, our department reported on BRONJ in a paper that provi...
Book
Wissenslücken schnell schließen Sie benötigen schnell eine bestimmte Information, haben keine Zeit für die Lektüre eines grundlegenden Lehrbuchs, wollen aber auf fachliche Tiefe nicht verzichten? Nutzen Sie Facharztwissen MKG-Chirurgie: · Alle Fakten auf das Wesentliche komprimiert · Von erfahrenen Herausgebern und Autoren geschrieben · Aktuelle Li...
Article
Introduction: The osteopathology of the jaws associated with bone resorption inhibitors is a current topic that engages a variety of clinical specialists. This has increased after the approval of denosumab for treatment of osteoporosis and skeletal-related events in patients with solid malignancy. Early after the first publications, there is a pos...
Article
Full-text available
Background and purpose: Imaging of bisphosphonate-induced osteonecrosis of the jaw is essential for surgical planning. We compared the extent of BONJ on contrast-enhanced MR imaging, [(18)F] fluoride PET/CT, and panoramic views derived from standard conebeam CT with clinical pre- and intraoperative examinations. Materials and methods: Between Fe...
Article
Segmental distraction osteogenesis of the anterior alveolar process is a sufficient method to enlarge the alveolar arch. Indications for this method are dental crowding, retroalveolism, and leveling of the curve of Spee. However, after the distraction period, the anterior alveolar segment often shows an unfavorable inclination resulting in nonphysi...
Article
Anterior alveolar osteodistraction is a common method for enlargement of the dentoalveolar process, and bone-borne distraction devices are hypothesized to avoid the risk of dental tipping and periodontal impairment during distraction. The aim of this study was to objectify this thesis and to determine the reliability of bone-borne osteodistraction...
Article
Objectives The aims of this study were to determine the bone mineral density (BMD) in bisphosphonate-related osteonecrosis of the jaw (BRONJ) by cone-beam computed tomography (CBCT) measurements and to correlate these measurements with the current stages recommended by the American Association of Oral and Maxillofacial Surgeons (AAOMS). Methods Bon...
Article
Growing skull fractures (GSFs) are rare complications after severe head injuries in the early childhood and rarely occur after craniosynostosis repair. The aim of this study was to define an algorithm for sufficient treatment for GSF after craniofacial procedures. Literature research was performed to clarify risk factors for GSFs after cranial vaul...
Article
Full-text available
8 years after discovery of osteonecrosis of the jaw associated with bisphosphonate therapy a lot of experience has been garnered in treating 112 patients with this disease. This disease, although uncommon, is still a burden for the patient as well as the treating specialists and an adequate standardised classification as well as therapy does not ex...
Article
Segmental distraction osteogenesis of the anterior mandibular alveolar process (frontblock) is a sufficient method to avoid extractions in patients with dental crowding and to decompensate retroalveolism. Up to now dental-borne devices were used, but limitate the indications for front-block distraction. A new bone-borne distraction device for mandi...
Article
QUESTIONS UNDER STUDY: 8 years after discovery of osteonecrosis of the jaw associated with bisphosphonate therapy a lot of experience has been garnered in treating 112 patients with this disease. This disease, although uncommon, is still a burden for the patient as well as the treating specialists and an adequate standardised classification as well...
Article
Objectives: Although there are many reports about risk factors for the development of BP-associated osteonecrosis of the jaws, the role of dental implants as a local risk factor is still discussed, especially in patients with oral BP treatment. Until now, a few case reports and surveys display a possible minor risk in patients with oral BP therapy...
Article
Segmental distraction osteogenesis of the anterior alveolar process has been introduced as a technique designed to avoid extractions in patients with severe dental crowding. The aim of this study was to quantify the degree of dental tipping within the alveolar segment after distraction osteogenesis. Patients treated for dental crowding, retruded an...
Article
Since the discovery that treatment with oral or intravenous bisphosphonate causes bisphosphonate-related osteonecrosis of the jaws (BRONJ), numerous articles on this disease have been published. The number of causative agents was extended after intervention of RANKL-inhibitor denosumab, which has been shown to be as well associated with osteopathol...
Article
Purpose: this study retrospectively analyzed the rate of screwed implant insertion and risk factors in patients undergoing mandibular reconstruction with microsurgical revascularized fibula flaps. Methods: This study retrospectively analyzed all patients with microvascularized fibula grafts between 1997 and 2005. Collected data included general...
Article
Full-text available
Growing skull fractures (GSFs) are rare complications after severe head injuries in the early childhood and rarely occur after craniosynostosis repair. The aim of this study was to define an algorithm for sufficient treatment for GSF after craniofacial procedures. Literature research was performed to clarify risk factors for GSFs after cranial vaul...
Article
The closure of wide palatal clefts and recurrent oronasal fistulae may be challenging. After repeated failure of conventional techniques, microvascular tissue transfer may be indicated in the closure of such fistulae. Depending on the location and the size of the palatal fistula, different tissues are required to sufficiently close the palatal gaps...
Article
Surgical navigation, though well-established, is often associated with extra effort for both patient and surgeon, and with additional exposure to radiation as a result of the necessary extra imaging. Osteoblastoma is a benign bone tumour, malignant transformation of which is rare but possible, and so resection is indicated. The orbit with surroundi...
Article
Technical developments strongly influence modern medicine. This is especially obvious in imaging technology. Today, one of the most difficult tasks for surgeons is transferring all the available imaging information for their patients into one "complete picture". In the operation theatre, this picture then has to be applied to the patient. Computer-...
Article
Sufficient closure of intraoral defects can be challenging. Various methods of tissue transfer have been presented in the literature. From skin grafts to microvascular flaps, most techniques used for intraoral reconstruction use skin to line out the oral cavity to guarantee an epithelial surface. Native mucosa tolerates the moist environment of the...
Article
The purpose of the study was to evaluate the indications, reliability, and complications of the radial forearm fasciocutaneous flap (RFFF) procedure in reconstructive head and neck surgery. The records of 81 patients who were treated with an RFFF between 1998 and 2009 were systematically reviewed. Data of recipient localization, previous T status,...
Article
Full-text available
Needle breakage in the oral cavity after local anesthesia is a common complication with possible serious complications of injuring vital structures. There are different possible reasons for needle breakage, with a main focus on preventable mistakes in treatment. In this study, an analysis of literature of the last 50 years as well as own cases has...
Article
Microsurgical revascularized fibula graft is a standard for the reconstruction of mandible or maxilla after major resection. Usually, screwed implants are inserted as a second procedure for dental rehabilitation. A lot has been published about the advantages of vascularized bone grafts, but until now there is only little information about long-term...
Article
Despite invention of titanium and resorbable screws and plates, still, one of the main challenges in bone fixation is the search for an ideal osteosynthetic material. Biomechanical properties, biocompatibility, and also cost effectiveness and clinical practicability are factors for the selection of a particular material. A promising alternative see...
Article
The complex 3-dimensional (3D) anatomy and geometry of the human skull and face combined with the need for precise symmetry poses challenges for reconstructive surgery of the region. Therefore, and with the technical improvements during the past 10 years or so, surgical navigation has become an established technique in craniomaxillofacial surgery....
Article
Blastomycosis is an uncommon male-predominant disease caused by the fungus Blastomyces dermatitidis. The lungs are most commonly affected, and other organs are usually involved by dissemination. Clinical feature and pathohistologic findings are similar to the appearance of squamous cell carcinoma. A 52-year-old male patient who has lived as a farme...
Article
Der Bruch einer Injektionsnadel ist in der zahnärztlichen Praxis ein eher seltenes, aber hinsichtlich möglicher Folgerisiken nicht zu unterschätzendes Ereignis. Beschrieben wird der Fall eines Patienten, der von seinem Hauszahnarzt zur Entfernung einer abgebrochenen Nadelspitze überwiesen wurde. Für diese Art von Zwischenfall werden verschiedene Ur...
Article
Full-text available
Myositis ossificans in the head and neck is a rare heterotropic bone formation within a muscle. Besides fibrodysplasia ossificans progressiva, traumatic and neurogenic forms are described in the literature. We are presenting the case of a 35-year-old female patient with a very rare form of MO of both masseter muscles after 4 weeks of intensive care...
Article
To assess quality of life (QOL) and psychiatric morbidity in successfully treated oral cavity squamous cell cancer (OC-SCC) survivors and their wives. Thirty-one men successfully treated for OC-SCC (mean, 3.7 years since diagnosis; UICC stages I to IV) together with their wives were assessed by questionnaires referring to QOL (WHOQOL-BREF), physica...
Article
Full-text available
Since four years from now on more and more information about bisphosphonate induced osteonecrosis of the jaws is published not only in professional journals, but also in the mass media. The result is a growing uncertainty of patients, but also professionals in dealing with this group of medication. Usually bisphosphonates are prescribed for treatme...
Article
Since four years from now on more and more information about bisphosphonate induced osteonecrosis of the jaws is published not only in professional journals, but also in the mass media. The result is a growing uncertainty of patients, but also professionals in dealing with this group of medication. Usually bisphosphonates are prescribed for treatme...
Article
Bisphosphonate-related osteonecrosis of the jaws (BON), first described in 2003, is gaining importance due to the increasing indication spectrum of bisphosphonate therapy [S. Takeyama, M. Ito, H. Shinoda, A novel bisphosphonate, TRK-530, for periodontitis, Bone 38 (2006) 31–31; M. Tagil, A. W-Dahl, J. Astrand, D. Little, S. Toksvig-Larsen, Decreasi...
Article
Full-text available
Bisphosphonates are frequently used drugs in the adjuvant therapy of bone metastases and tumour-induced hypercalcaemia, but also for osteoporosis or Pagets disease. Several publications within the last three years considered osteonecrosis of the jaws to be connected with bisphosphonate therapy. Until today possible treatment strategies contain anti...

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