Christiane Montag

Christiane Montag
Charité Universitätsmedizin Berlin | Charité · Department of Psychiatry and Psychotherapy

PD Dr. med.

About

87
Publications
36,899
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1,463
Citations
Citations since 2017
58 Research Items
846 Citations
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2017201820192020202120222023050100150200
2017201820192020202120222023050100150200

Publications

Publications (87)
Article
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Background Even in the early stages, global crises such as the COVID-19 pandemic lead to serious dislocations of social life, secondary adjustment reactions to external restrictions and individual concerns. Coping mechanisms may also include dysfunctional strategies like an increase of drug use. Considering the wide-spread use of cannabis, the aim...
Article
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Functional impairment is a core feature of both autism and schizophrenia spectrum disorders. While diagnostically independent, they can co-occur in the same individual at both the trait and diagnostic levels. The effect of such co-occurrence is hypothesized to worsen functional impairment. The diametric model, however, suggests that the disorders a...
Article
Synthetic metacognition is a heterogeneous construct related to psychotic disorders. One important tool to assess this construct is the Metacognition Assessment Scale - Abbreviated (MAS-A). In this study, we investigated the latent structure as well as the interrater reliability and convergent and incremental validity of the MAS-A in a sample of pa...
Article
The ability to imitate is considered impaired in schizophrenia patients. This assumption, however, is based on heterogeneous studies mostly targeting voluntary imitation, e.g., pantomime. Studies on automatic imitation, however, and on underlying mechanisms of top-down inhibition of automatic imitation and contextual modulation in schizophrenia are...
Article
Background : The COVID-19 pandemic is presumably having an impact on the consumption of psychoactive substances. Social distancing and lockdown measures may particularly affect the use of “party drugs” (e.g., stimulants, dissociatives, and GHB/GBL) through the absence of typical use settings. We aimed to analyse the use patterns of those substances...
Article
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Background Post-coercion review has been increasingly regarded as a useful intervention in psychiatric inpatient setting. However, little is known about its effect on perceived coercion. Methods A multicenter, two-armed, randomized controlled trial was conducted, aiming at analyzing the effect of post-coercion review on perceived coercion. People...
Article
3,4-methylenedioxymethamphetamine (MDMA/“ecstasy”) is widespread in the electronic club scene, but MDMA has also been suggested for the treatment of anxiety spectrum disorders like posttraumatic stress disorder (PTSD) and social anxiety in autistic adults. Here, we report a case of a high functioning 24-old student with a sporadic recreational use...
Article
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Theory of mind (ToM) is an aspect of social cognition impaired in different addictive disorders, including opioid addiction. This study aimed at replicating ToM deficits in opioid dependent patients undergoing opioid maintenance treatment (OMT) and exploring the influence of substance use related variables, executive functions and childhood maltrea...
Article
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The ability to mentalize (i.e., to form representations of mental states and processes of oneself and others) is often impaired in people with schizophrenia spectrum disorders. Emotional awareness (EA) represents one aspect of affective mentalizing and can be assessed with the Levels of Emotional Awareness Scale (LEAS), but findings regarding indiv...
Article
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Introduction: The current corona virus disease (COVID-19) pandemic has caused a serious global health crisis that has affected large parts of the public and private life worldwide, including the use of psychoactive substances. In this study, we investigated the effect of the COVID-19 pandemic on the use of serotonergic psychedelics, i.e., the setti...
Article
Introduction: Abrupt discontinuation of antipsychotics is associated with an increased risk of adverse events such as extrapyramidal symptoms in humans. In animal models, vacuous chewing movements may occur after antipsychotic discontinuation. We aim to assess vacuous chewing movements after the discontinuation of second-generation antipsychotics...
Article
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Background: The COVID-19 pandemic may lead to negative mental health effects but the effect on alcohol consumption among younger adults is unclear. We assess predictors of change in alcohol consumption during the first phase of the COVID-19 pandemic among younger adults. Methods: This cross-sectional internet-based survey was part of an overarching...
Article
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Exposure to childhood trauma is a well-known risk factor for severe mental disorders including schizophrenia and other non-affective psychoses. Beyond childhood trauma, there is increasing evidence that bullying, social exclusion, and discrimination during adolescence and adulthood may increase the risk of developing a psychotic disorder, and that...
Article
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Objective Post-coercion review is increasingly regarded as a mean to reduce the negative consequences of coercive interventions, including the development of posttraumatic symptoms. However, the efficacy of this intervention in preventing posttraumatic symptoms or PTSD has not been sufficiently studied. The objective of this study is to examine the...
Article
Studies on schizophrenia (SCZ) and aberrant multisensory integration (MSI) show conflicting results, which are potentially confounded by attention deficits in SCZ. To test this, we examined the interplay between MSI and intersensory attention (IA) in healthy controls (HCs) (N = 27) and in SCZ (N = 27). Evoked brain potentials to unisensory-visual (...
Article
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Many determinants leading to the use of different coercive measures in psychiatry have been widely studied and it seems that staff attitudes play a crucial role when it comes to the decision-making process about using coercion. However, research results about staff attitudes and their role in the use of coercive measures are inconsistent. This migh...
Article
Prejudices can lead to discrimination, social exclusion, and violence particularly among young male adults. Previous findings suggest that the degree of holding prejudices is linked to low levels of empathy, while low levels of empathy have been associated with alexithymia, the inability to experience one’s own feelings. We tested the hypothesis th...
Article
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In the original article, the reference number #36 is listed with the wrong list of authors. The first author was unfortunately omitted. The correct reference #36 should read: Lasalvia A, Bonetto C, Tosato S, Cristofalo D, Salazzari D et al (2014) First-contact incidence of psychosis in north-eastern Italy: influence of age, gender, immigration and...
Preprint
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Previous conflicting findings on multisensory integration in schizophrenia might be related to differences in top-down attention demands across the different studies. We tested this with a visuo-tactile stimulation paradigm and high-density event-related potentials (ERPs) to examine the interplay between multisensory integration and top-down inters...
Article
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Background Computational linguistic methodology allows quantification of speech abnormalities in non-affective psychosis. For this patient group, incoherent speech has long been described as a symptom of formal thought disorder. Our study is an interdisciplinary attempt at developing a model of incoherence in non-affective psychosis, informed by co...
Poster
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Background Healthy metacognition involves several capacities, including the ability to integrate information about the self and others in order to formulate ways of coping with social challenges and psychological distress. Multiple studies have demonstrated that reduced general metacognitive capacity is predictive of the development and persistence...
Article
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Endogenous oxytocin has been associated with different aspects of social cognition in healthy subjects and patients with schizophrenia. In this pilot study, we investigated the relationship between plasma oxytocin and oxytocin level changes induced by empathy-eliciting, attachment-related movie scenes with correlates of cognitive and emotional empa...
Article
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Systematic reviews and meta-analyses suggest that there are increased rates of schizophrenia and related psychoses in first- and second-generation migrants and refugees. Here, we present a meta-analysis on the incidence of non-affective psychotic disorders among first- and second-generation migrants. We found substantial evidence for an increased r...
Article
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Background Impairments of social cognition are considered core features of schizophrenia and are established predictors of social functioning. However, affective aspects of social cognition including empathy have far less been studied than its cognitive dimensions. The role of empathy in the development of schizophrenia remains largely elusive. Me...
Article
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Primary aim of this study was to determine the extent and type of self-reported interpersonal problems in patients with non-affective psychoses and their impact on psychosocial functioning. Furthermore, we aimed to explore potential links with the psychodynamic construct of Stavros Mentzos' "psychotic dilemma", which describes an insufferable inner...
Article
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Synthetic metacognition is defined by integrative and contextualizing processes of discrete reflexive moments. These processes are supposed to be needed to meet intrapsychic as well as interpersonal challenges and to meaningfully include psychotic experience in a personal life narrative. A substantial body of evidence has linked this phenomenon to...
Article
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A diagnosis of schizophrenia is associated with a heterogeneous psychopathology including positive and negative symptoms. The disconnection hypothesis, an early pathophysiological framework conceptualizes the diversity of symptoms as a result of disconnections in neural networks. In line with this hypothesis, previous neuroimaging studies of patien...
Article
Schizophrenia has been understood as a network disease with altered functional and structural connectivity in multiple brain networks compatible to the extremely broad spectrum of psychopathological, cognitive, and behavioral symptoms in this disorder. When building brain networks, functional and structural networks are typically modeled independen...
Poster
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Abstract: Introduction: People with schizophrenia (SZ) could have deficits in attentional filtering and integration of multisensory input, which are essential for veridical perception of the external world. Previous studies of SZ show deficits in unisensory attention, reflected in altered evoked brain potentials. In this intersensory attention st...
Conference Paper
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Incoherent discourse in schizophrenia has long been recognized as a dominant symptom of the mental disorder (Bleuler, 1911/1950). Recent studies have used modern sentence and word embeddings to compute coherence metrics for spontaneous speech in schizophrenia. While clinical ratings always have a subjective element, computational linguistic methodo...
Article
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Das Weddinger Modell ist ein aus der stationären Praxis heraus entwickeltes Recovery-orientiertes Behandlungsmodell, das im Rahmen eines komplexen „Change-Projektes“ 2010 in der Psychiatrischen Universitätsklinik der Charité im St. Hedwig-Krankenhaus implementiert wurde. Alle stationären Strukturen wurden hinsichtlich konsequenter Transparenz, Part...
Article
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Zusammenfassung Die Vermeidung von Zwangsmaßnahmen auf Akutstationen mit Versorgungsauftrag war Ziel von zwei Stationskonzepten, die in benachbarten Berliner Bezirken im Abstand von 10 Jahren implementiert wurden. Beide Konzepte haben zu einer deutlichen Reduktion von Zwangsmaßnahmen geführt. Die Mitnahme des Teams war für eine erfolgreiche Umsetzu...
Preprint
Full-text available
Schizophrenia is described as a disease in which complex psychopathology together with cognitive and behavioral impairments are related to widely disrupted brain circuitry causing a failure in coordinating information across multiple brain sites. This led to the hypothesis of schizophrenia as a network disease e.g. in the cognitive dysmetria model...
Preprint
Full-text available
Schizophrenia has been understood as a network disease with altered functional and structural connectivity in multiple brain networks compatible to the extremely broad spectrum of psychopathological, cognitive and behavioral symptoms in this disorder. When building brain networks, functional and structural networks are typically modelled independen...
Preprint
Full-text available
A diagnosis of schizophrenia is associated with a heterogeneous psychopathology including positive and negative symptoms. The disconnection hypothesis, an early pathophysiological framework conceptualizes the diversity of symptoms as a result from disconnections in neural networks. In line with this hypothesis, previous neuroimaging studies of pati...
Article
Full-text available
Background: Oxytocin (OXT) is critically involved in the regulation of attachment and interpersonal function. In this study, emotional children's movies were used to stimulate OXT secretion in patients with schizophrenia and healthy controls. Furthermore, associations of OXT levels with measures of attachment style (Psychosis Attachment Measure),...
Article
Zusammenfassung Ziel Pilotstudie zur Untersuchung eines Leitfadens zur standardisierten Nachbesprechung erfolgter Zwangsmaßnahmen. Methodik Nach Durchführung von 12 Nachbesprechungen wurden teilnehmende Patienten und Mitarbeiter mittels eines selbstentwickelten Fragebogens mit quantitativen und qualitativen Fragen sowie qualitativer Experten-Interv...
Article
Zusammenfassung Die berechtigte Forderung nach Vermeidung von Zwang in der der psychiatrischen Behandlung erfordert ein geglücktes Zusammenspiel von Veränderungen struktureller Voraussetzungen und therapeutischer Prozesse, aber auch individueller Haltungen und Fertigkeiten. Der Artikel beschreibt aktuelle therapeutische Ansätze und Möglichkeiten, d...
Article
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Clinical studies suggest aberrant neurotransmitter concentrations in the brains of patients with schizophrenia (SCZ). Numerous studies have indicated deviant glutamate concentrations in SCZ, although the findings are inconsistent. Moreover, alterations in glutamate concentrations could be linked to personality traits in SCZ. Here, we examined the r...
Article
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Intensive outpatient models of need-adapted psychiatric care have been shown to reduce the length of hospital stays and to improve retention in care for people with severe mental illnesses. In contrast, evidence regarding the impact of such models on involuntary hospital treatment and other coercive measures in inpatient settings is still sparse, a...
Article
Objective: To examine the impact of coercive interventions (CI) on patients’ evaluations of psychiatric hospitals as adversaries versus allies. Methods: Self-constructed interviews were conducted relating to quantitative and subjective aspects of coercion and the attitude towards psychiatry of 79 patients with psychotic and bipolar disorders. The C...
Article
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Objectives: Metacognition, the capacity 'to think about thinking' and thus to reflect and to master interpersonal problems on a mentalistic basis, is often impaired among patients with schizophrenia spectrum disorders and has been suggested as a potential treatment target. However, little is known about the reliability of its measurement and links...
Article
Background: Autism and schizophrenia are associated with difficulties in social perception and understanding. However, the relationship between these conditions and the way they affect social functioning have been a contentious issue. In addition, a dimensional view of psychopathology suggests that subclinical expressions can explain interindividua...
Article
Background: Chronic cannabis use may cause neurocognitive deficits and increase the risk of psychosis. Nevertheless, the effects of cannabis use on neurocognitive functioning in schizophrenia have remained largely unspecified. Methods: Here, we studied repetition suppression of auditory event-related responses in a paired-stimulus design in a mi...
Article
Anliegen Präventionsstrategien und Präferenzen von Zwangsmaßnahmen (ZM) wurden aus der Sicht von psychiatrischen Patienten erfasst. Methode Teilstrukturierte Interviews mit 90 überwiegend zwangserfahrenen Patienten mit psychotischen Erkrankungen. Ergebnis und Diskussion Aus Patientensicht könnten ZM durch ein größeres Angebot an Einzeltherapien, Ve...
Article
Full-text available
Mentalization denotes the ability to perceive, represent and reflect one’s own and also foreign mental states. It is developed within a secure attachment relationship and forms the basis for regulation of emotions and the self as well as for the development of metacognitive functions. In the field of psychoses mentalization disorders have received...
Article
Long-term cannabis use may confer cognitive deficits and increased risk of psychosis. However, the relationship between cannabis use and schizophrenia is complex. In particular, little is known about the effects of chronic cannabis use on the attention-related electric brain response in schizophrenia. We investigated auditory novelty and oddball P3...
Article
Full-text available
Under certain conditions, coercive interventions in psychotic patients can help to regain insight and alleviate symptoms, but can also traumatize subjects. This study explored attitudes towards psychiatric coercive interventions in healthy individuals and persons suffering from schizophrenia, schizoaffective or bipolar disorder. The impact of perso...
Article
Beyond symptom remission, recovery aims at inclusion and social participation of psychiatric patients irrespective of remaining symptoms and disabilities. It thus places a focus on the patients’ individual resources and creativity, which enable them to participate in society. It also places a strong focus on social exclusion and stigmatization, may...
Article
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The United Nation’s Convention on the Rights of Persons with Disabilities as well as rulings of the highest constitutional court in Germany (Bundesverfassungsgericht) have emphasized and defined humans rights in psychiatry and directed therapeutic efforts towards social inclusion. We describe key aspects of the convention and some court rulings and...
Article
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This pilot study aimed to evaluate the feasibility of an assessor-blind, randomised controlled trial of psychodynamic art therapy for the treatment of patients with schizophrenia, and to generate preliminary data on the efficacy of this intervention during acute psychotic episodes. Fifty-eight inpatients with DSM-diagnoses of schizophrenia were ran...
Article
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Nach einer theoretischen Einführung werden die Problembereiche bei schizophrenen Psychosen und das spezifische therapeutische Vorgehen genau und nachvollziehbar dargestellt. Neben Hinweisen zu Vorgespräch und Rahmenbedingungen wird das therapeutische Vorgehen durch konkrete Beispiele aus psychodynamischen Psychosetherapien beschrieben. Der therapeu...
Article
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The nonapeptide oxytocin (OXT) and its receptor (OXTR) have been implicated in social cognition, empathy, emotion and stress regulation in humans. Previous studies reported associations between OXT and OXTR genetic polymorphisms and risk for disorders characterized by impaired socio-emotional functioning, such as schizophrenia and autism. Here we i...
Data
MANCOVA of 3 IRI scores in schizophrenia patients (SZ, n = 145) and healthy controls (HC, n = 145); factors: OXTR rs2254298 (GG vs. A carriers), gender and diagnosis, covariate: verbal IQ and educational years. (DOCX)
Article
Dysfunctional activity in the orbitofrontal cortex (OFC) is one of the core features in the pathophysiology of obsessive-compulsive disorder (OCD). Neuroimaging studies indicate orbitofrontal hyperactivation during the resting state as well as during symptom provocation, whereas orbitofrontal hypoactivation has been reported during tasks designed t...
Article
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Objectives: Dysfunctions of the "social brain" belong to the core features of schizophrenia. The neurohormone oxytocin (OXT), mediated through its specific receptor (OXTR), is involved in the regulation of social behaviour and social cognition. Previous research has suggested a role of OXT system genes in disorders of social reciprocity. Prelimina...
Article
Background Diffusion Tensor Imaging studies have repeatedly shown a decrease of the fractional anisotropy (FA) parameter in patients with schizophrenia. This has been interpreted as a disturbed microstructural integrity of white matter. However, FA is a relative parameter that is derived from eigenvalues of the diffusion tensor and FA reductions ma...
Article
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Alterations of theory of mind (ToM) and empathy were implicated in the formation of psychotic experiences, and deficits in psychosocial functioning of schizophrenia patients. Inspired by concepts of neurocognitive endophenotypes, the existence of a distinct, potentially neurobiologically based social-cognitive vulnerability marker for schizophrenia...
Article
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Deficits of theory of mind and empathy have been reported in bipolar disorder and schizophrenia. Despite a range of common characteristics of both disorders, significant differences exist in the field of social cognition. The article reviews current evidence concerning social cognition in bipolar disorder and presents new empirical data on theory o...
Article
Zusammenfassung Sozial-kognitive Funktionen wie Theory of Mind (ToM) und Empathie finden bei der bipolaren affektiven Störung zunehmende Beachtung. Trotz einiger klinischer und neurobiologischer Gemeinsamkeiten mit der Schizophrenie zeigen sich im Hinblick auf die soziale Kognition entscheidende Unterschiede zwischen beiden Erkrankungen. Der Artike...
Article
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In schizophrenia, impairments of theory of mind (ToM) may be due to excessive ('overmentalizing') or defective ('undermentalizing') attribution of mental states. However, most ToM tests differentiate neither between 'overmentalizing' and 'undermentalizing' nor between cognitive and affective ToM in schizophrenia. This study aimed at differentiating...
Article
Full-text available
Deficits in social cognition, e.g. theory of mind (ToM) represent core characteristics involved in the etiology of psychopathological symptoms and an important predictor of social competence. In bipolar affective disorder, evidence for ToM deficits is scant, although brain imaging studies and impairments in non-social neurocognitive domains indicat...