Christian Apfelbacher

Christian Apfelbacher
Otto-von-Guericke-Universität Magdeburg | OvGU · Institute of Social Medicine and Health Systems Research

Prof. Dr. PhD

About

426
Publications
45,478
Reads
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6,462
Citations
Additional affiliations
November 2010 - present
Universität Regensburg
May 2008 - October 2010
Universitätsklinikum Heidelberg
Position
  • Research Associate
May 2008 - October 2010
Universität Heidelberg
Position
  • Academic research fellow

Publications

Publications (426)
Article
Background: Childhood maltreatment (CM) is related to poor physical and mental health outcomes in adults. Knowledge on the impact of CM on skin diseases is limited, and no study has previously addressed the association of CM with atopic dermatitis (AD) in adult age. Objectives: To analyze the prevalence of CM in individuals with physician-diagno...
Conference Paper
Objectives: Parents may take on a crucial role in making prevention-and care-related decisions for their (infant) child, but various factors, such as the ability to distinguish good from bad health information, may impact on this task. Our objective was to empirically assess parents' knowledge and awareness about early childhood allergy prevention...
Article
Full-text available
Atopic dermatitis (AD) is a common chronic inflammatory skin condition which impacts psychological wellbeing and social relationships. There have been studies of AD’s impact on quality of life (QoL) in Western countries, but these findings cannot be directly extrapolated to Asian populations with genetic, environmental and cultural differences. The...
Article
Background: Recap of atopic eczema (RECAP) is a patient-reported outcome measure (PROM) assessing eczema control. This instrument has been developed and validated in the UK. There is a self-reported and a proxy-reported version in English, Dutch and German. However, it is unclear whether the self-reported version shows adequate content validity wh...
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Zusammenfassung Im Kontext der COVID-19-Pandemie stehen die empirisch Forschenden vor besonderen Herausforderungen: Da Kontaktbeschränkungen persönliche Formate verhinderten, galt es nicht nur die Datenerhebungen, sondern auch die qualitative Interpretationsarbeit (Datenauswertung) im virtuellen Raum zu gestalten. In diesem Beitrag skizzieren wir e...
Article
Background Extended reality, which encompasses virtual reality (VR), augmented reality (AR), and mixed reality (MR), is increasingly used in medical education. Studies assessing the effectiveness of these new educational modalities should measure relevant outcomes using outcome measurement tools with validity evidence. Objective Our aim is to dete...
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Since the WHO’s “Influenza Pandemic Preparedness Plan” in 1999, pandemic preparedness plans at the international and national level have been constantly adapted with the common goal to respond early to outbreaks, identify risks, and outline promising interventions for pandemic containment. Two years into the COVID-19 pandemic, public health experts...
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Hintergrund: Influenzainfektionen und Herzerkrankungen gehen mit negativen Wechselwirkungen einher: Zum einen steigt während einer Infektion mit Influenzaviren das Risiko für das Auftreten eines Herzinfarktes. Zum anderen ist das Risiko für schwere oder tödliche Erkrankungsverläufe der Influenza bei Menschen mit kardiologischen Vorerkrankungen erhö...
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PurposeTo critically appraise, compare and summarize the quality of all existing PROMs that have been validated in hyperhidrosis to at least some extend by applying the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology. Thereby, we aim to give a recommendation for the use of PROMs in future clinical...
Article
Objectives: Cholestasis and elevated serum bile1 acid levels are common in critically ill patients. This study aims to define the specific pattern of bile acids associated with acute respiratory distress syndrome (ARDS) and the changes in pattern over time. Methods: Prospective observational study. Serum samples of 70 ARDS patients were analyzed...
Article
Core outcome sets (COS) are critically important outcomes that should be measured in clinical trials. Their absence in atopic dermatitis (AD) is a form of research waste and impedes combining evidence to inform patient care. Here, we articulate the rationale for COS in AD and review the work of the international Harmonising Outcome Measures for Ecz...
Article
Full-text available
This study aimed to compare worries related to the Coronavirus disease 2019 (COVID-19) in families with young children in two regions in Germany differently affected by the pandemic (Regensburg in Southeast Germany, Leipzig in Eastern Germany) during the first and the second waves of the COVID-19 pandemic. 720 parents participating in the KUNO Kids...
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Full-text available
Individuals with chronic conditions have been faced with many additional challenges during the COVID-19 pandemic. Individual health literacy (HL) as the ability to access, understand, evaluate, and apply pandemic-related information has thus become ever more important in these populations. The purpose of this study was to develop and content-valida...
Article
Background Urbanization and biodiversity loss are linked to chronic disorders, in particular allergic diseases. The aim of this scoping review was to provide a synopsis of intervention studies specifically examining the influence of exposure to natural environments on human microbiota as well as immunological markers as suggested interlink between...
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Objectives: To gain insights into the impact of the COVID-19 pandemic on ongoing health research projects, using projects from a selected funding programme in Germany as an example. Design: Online survey and validation workshop. Setting: Lockdowns and social distancing policies impact on clinical and public health research in various forms, es...
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Background Measures to manage the COVID-19 pandemic have led to impacts on healthcare systems and providers worldwide. Outpatient healthcare professionals (HCPs) provide the majority of patient care. Insight into their experiences during a pandemic is rare. Therefore, we explored how primary and secondary care HCPs in a rural area in Germany experi...
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Full-text available
Background Recap of atopic eczema (RECAP) is a patient-reported outcome measure (PROM) assessing eczema control. Long-term control of eczema is one of the four core outcome domains for atopic eczema trials. This instrument has been recently developed in the UK. Objective This study aimed to translate the English RECAP into German and test its cont...
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Background: Early exposure to digital media may affect the physical and cognitive development in young children. The American Academy of Pediatrics and national guidelines recommend no digital media use at all under the age of 18 months. The aim of our study was to determine the actual exposure to digital media in 12-month-old infants and to reveal...
Article
Background Hand eczema is a common inflammatory skin disorder in both adolescence and adulthood. Objectives We sought to assess the lifetime prevalence of hand eczema and associated exogenous and endogenous risk factors among adolescents in Germany. Methods This was a cross-sectional study embedded into a prospective population-based birth cohort...
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Background Our aim was to gain insight into the experiences of women suffering from the urinary component of the Genitourinary Syndrome of Menopause (GSM) and to understand the impact of urinary complaints as part of GSM on the lives of affected women. Design Qualitative study. Setting Online, primary care. Participants and methods Postmenopausa...
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Purpose: Despite the health benefits of full breastfeeding for both infants and mothers, less than 50% of mothers in Germany practice this method for at least 4 months after childbirth. Because of the growing importance of health literacy to improve public health, we investigated the role of maternal health literacy in breastfeeding behavior. Met...
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Abstract Background Seasonal influenza vaccination has been recommended for pregnant women in Germany since 2010. The aim of this study was to examine prevalence and determinants of receipt of provider recommendation for influenza vaccination as well as influenza vaccination uptake during pregnancy. Methods We analysed data from the “KUNO Kids Heal...
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Introduction German government regulations such as physical distancing and limited group numbers, designed to curb the spread of COVID-19, have had far-reaching consequences for the very foundations of social life. They have, to name only a few, transformed greetings and goodbyes, blurred private and public worlds, and complicated basic communicati...
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Hintergrund: Herzerkrankungen wie die koronare Herzkrankheit (KHK), die Herzinsuffizienz (HI) und das Vorhofflimmern (VHF) gehören zu den Erkrankungs- und Todesursachen, die in den westlichen Industrienationen am häufigsten vertreten sind. Vorherige Studien zeigen starke Unterschiede der Prävalenz von KHK und HI zwischen den deutschen Bundesländer....
Article
Background Population-based data regarding the relationship between childhood maltreatment (CM), somatization and health-related quality of life (HRQoL) in adults are limited. Objective To investigate the association of CM history (emotional and physical abuse and neglect, sexual abuse) with somatization and with physical and mental HRQoL in adult...
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IntroductionMalignant melanoma is an aggressive skin tumor with a good prognosis when treated in an early tumor stage, but has a poor prognosis with distant metastases. The incidence of malignant melanoma has increased continuously over the last decades, with little change in mortality. One explanation for this is that melanomas are increasingly de...
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Background Wearing face masks in public is recommended under certain circumstances in order to prevent infectious diseases transmitted through droplets.AimThe objective was to compile all German and English research results from peer-reviewed journal articles using a sensitive literature search on the effects of mask-wearing for preventing infectio...
Article
Background The prevalence of food allergies (FA) in children increased rapidly at the turn of the century. The EuroPrevall study identified Germany as a country with very high prevalence of FA at that time. Using two large German birth cohorts we provide an update of the status quo ten years later. Methods KUNO Kids and Ulm SPATZ Health studies ar...
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Full-text available
School closures have a negative impact on physical and mental well-being, and education, of children and adolescents. A surveillance programme to detect asymptomatic SARS-CoV-2 infection could allow schools to remain open, while protecting the vulnerable. We assessed the feasibility of a programme employing gargle samples and pool testing of indivi...
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Introduction: Serologic studies are crucial for clarifying the regional dynamics of the SARS-CoV-2 coronavirus pandemic as well as the success of a vaccination campaign against COVID-19. We describe a cohort study investigating the seroprevalence of antibodies against SARS-CoV-2 in Magdeburg (Saxony-Anhalt, Germany). Protocol and study design: The...
Conference Paper
Hintergrund und Stand (inter)nationaler Forschung: Der Innovationsfonds soll durch die Entwicklung neuer Versorgungskonzepte eine versorgungswissenschaftlich evaluierte Weiterentwicklung der Gesundheitsversorgung erzielen. Die Ad-hoc-Kommission „Innovationfonds“ des Deutschen Netzwerk Versorgungsforschung möchte, Qualität und Potenzial bisher geför...
Conference Paper
Einleitung Serologische Tests auf Antikörper gegen SARS-CoV-2 sind ein essenzieller Baustein zur Einschätzung des Infektionsgeschehens in der COVID-19-Pandemie. Regionale Seroprävalenzstudien vermitteln ein genaueres Bild auf lokaler Ebene und leisten einen wichtigen Beitrag, um den bundesweiten Pandemieverlauf besser einzuschätzen. Methoden In de...
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Titel: „Also, wir haben auch ganz viele Bewohner, die sagen: "Nehmt jetzt euren Maulkorb endlich ab!" - Perspektiven von Pflegekräften und Mitarbeitenden in pandemischen Zeiten Hintergrund: Die massiven Auswirkungen der sozialen und politischen Maßnahmen der Covid-19-Pandemie zeigen sehr deutlich bereits bekannte Herausforderungen hinsichtlich de...
Conference Paper
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Titel: Die pandemische pflegerische Langzeitversorgung – Denkanstöße aus dem Forschungsprojekt CoronaCare Der Hintergrund: Mit Aufkommen der Pandemie erfahren Pflegeheimbewohner:innen die Zuschreibung der besonders gefährdeten Risikogruppe. Die Wahrscheinlichkeit eines schweren Verlaufs, der bis zum Tod führen kann, ist bei dieser Gruppe aufgrund...
Article
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Background The aim of this study was to examine the interaction of a multitude of socio-economic, lifestyle, environmental, psychosocial and birth related determinants and their effect on maternal health four weeks after delivery. Methods We used data from a German birth cohort study, the KUNO-Kids health study. Social determinants, as well as the...
Conference Paper
Background Healthcare professionals (HCPs) in critical care had to adapt rapidly through the COVID-19 pandemic, including adjusting to a new, unknown disease pattern with severe disease progression, organizing work continuously in personal protective equipment, new knowledge, and constant new information about the pandemic and response efforts. In...
Conference Paper
Background: In Germany the pandemic is assuming historic dimensions that cannot yet be fully assessed. The sociopolitical regulations designed to curb the spread of the virus have transformed social interaction with the introduction of mandatory physical distancing and limited social gatherings as well as strict hygiene measures. Older people are c...
Conference Paper
Background: In Germany the pandemic is assuming historic dimensions that cannot yet be fully assessed. The sociopolitical regulations designed to curb the spread of the virus have transformed social interaction with the introduction of mandatory physical distancing and limited social gatherings as well as strict hygiene measures. Older people are c...
Article
Full-text available
Background The long-term sequalae of COVID-19 remain poorly characterised. We assessed persistent symptoms in previously hospitalised patients with COVID-19 and assessed potential risk factors. Methods Data were collected from patients discharged from 4 hospitals in Moscow, Russia between April 8 and July 10, 2020. Participants were interviewed vi...
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Background The Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire is a validated patient-reported outcome measure (PROM) capturing the impacts of vaginal symptoms in postmenopausal women. Aim We aimed to psychometrically validate the German version of the DIVA questionnaire. Methods Data was collected online and by paper-pencil. We ran confi...
Article
This systematic review aims to provide an update on measurement properties of patient-reported outcome measures for pruritus. A Medline literature search was conducted to update the systematic review published by Schoch et al. in 2017 and to identify new validation studies published between October 2015 and July 2019. The methodological quality of...
Article
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Background: Research in early childhood allergy prevention (ECAP) is flourishing and new intervention strategies have proven to be promising. Due to the dynamic nature of ECAP, gaps between what is known and how guidelines inform practice are likely. A living systematic review (LSR) can narrow this gap by incorporating new evidence as it becomes av...
Article
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Please cite this article as: Osmanov IM, Spiridonova E, Bobkova P, et al. Risk factors for long covid in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study. Eur Respir J 2021; in press (https://doi.
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Introduction: The evaluation of the testicular position in newborns is important to ensure timely initiation of therapy. The aim of our study was to assess the reliability of a routinely performed screening examination. Patients and methods: Newborns were examined by a pediatrician between 48 and 72 h after birth. Boys with suspected cryptorchid...
Conference Paper
Conference of the British Society of Gerontology. Backround: Nursing home residents were identified as a particularly vulnerable risk group: they have a particularly severe course of the viral disease due to chronic and multimorbid diseases, which can ultimately end in death. In the CoronaCare project, research is being conducted in Germany in long...
Article
Full-text available
Background The long-term sequelae of coronavirus disease 2019 (Covid-19) in children remain poorly characterised. This study aimed to assess long-term outcomes in children previously hospitalised with Covid-19 and associated risk factors. Methods This is a prospective cohort study of children (≤18 years old) admitted with confirmed Covid-19. Child...
Article
Objectives Independent of the underlying disease, intensive care unit survivors often suffer from cognitive, physical and mental impairments, also known as post-intensive care syndrome (PICS). Specific follow-up services are recommended for these patients. This study aims to capture the perspectives of health care providers on the development of th...
Preprint
Full-text available
Background: Appropriate health system utilisation during pregnancy is fundamental for maintaining maternal and child’s health. This study provides comprehensive data on supplementary prenatal diagnostics use and its influencing factors in Germany. Methods: We obtained data from a recently established prospective German birth cohort study, the KUNO...
Article
Full-text available
Dear Editor, BIOMAP (BIOMarkers in Atopic dermatitis and Psoriasis) is a large European consortium aiming to advance personalised medicine for atopic dermatitis and psoriasis by identifying biomarkers which predict therapeutic response and disease progression. BIOMAP brings together clinicians, researchers, patient organisations and pharmaceutical...
Preprint
Full-text available
Background The present study aimed to compare worries related to the Coronavirus disease 2019 (COVID-19) in families with young children in two regions in Germany differently affected by the pandemic (Regensburg in Southeast Germany, Leipzig in Eastern Germany) during the first and the second wave of the COVID-19 pandemicMethods720 parents particip...
Article
Full-text available
Stigmatization from work-related COVID-19 exposure has not been investigated in detail yet. Therefore, we systematically searched three databases: Medline, Embase, and PsychInfo (until October 2020), and performed a grey literature search (until February 2021). We identified 46 suitable articles from 24 quantitative and 11 qualitative studies, 6 sy...
Article
Full-text available
Background Hyperhidrosis is a chronic skin condition that impairs the patient’s quality of life (QoL). There are several patient-reported outcome measures (PROMs) for patients affected by hyperhidrosis available; however an evidence-based assessment of their quality has not been undertaken so far. Objective In our systematic review, we aim to iden...
Article
Full-text available
Background Hand eczema (HE) is a chronic inflammatory skin disease caused by a genetic predisposition and environmental exposures. There is a lack of population-based studies on skin diseases in the elderly. Objectives Our aim was to estimate the frequency of HE in the elderly to determine its burden of disease in this particular population. Mate...
Preprint
Full-text available
Background: The prevalence of food allergies (FA) in children increased rapidly at the turn of the century. The EuroPrevall study identified Germany as a country with very high prevalence of FA at that time. Using two large German birth cohorts we provide an update of the status quo ten years later. Methods: KUNO Kids and Ulm SPATZ Health studies a...
Article
Full-text available
Background: School closures are a widely implemented strategy for limiting infection spread in the current COVID-19 pandemic. The negative impact of school closures on children and young people is increasingly apparent, however. Objective: We aim to evaluate the feasibility of an infection monitoring program in schools to enable targeted quarantini...