Chithranganie Perera

• Doctor of Public Health
• Consultant Community Physician at The School of Public Health UQ

Improve the quality and coverage of National Cervical Cancer Screening programme

Background Cervical cancer is the 2nd most common female cancer among Sri Lankan females and is almost associated with sexually transmitted cervicovaginal human papillomavirus (HPV) infection. The study objectives were to determine the prevalence of vaginal and cervical HPV infection among 35year old ever-married women and assess the validity of pr...

Background Cervical cancer is the 2nd most common female cancer among Sri Lankan females and is almost associated with sexually transmitted cervicovaginal human papillomavirus (HPV) infection. The study objectives were to determine the prevalence of vaginal and cervical HPV infection among 35year old ever-married women and assess the validity of pr...

Background Ovarian cancer is the sixth most prevalent and fatal cancer among females worldwide. Antioxidants have some proven anticancer effects by limiting oxidative stress. Selenium is a powerful antioxidant and protects cells from the destruction caused by peroxides. This study aimed to determine the association between selenium intake and Epith...

Background Cervical cancer is the 2 nd most common female cancer among Sri Lankan females and is almost associated with sexually transmitted cervicovaginal human papillomavirus (HPV) infection. The study objective is to determine the prevalence of vaginal HPV infection among ever-married

Background Cervical cancer is the 2nd most common female cancer among SriLankan female and is almost associated with sexually transmitted cervicovaginal human papillomavirus (HPV) infection. The study objective is to determine the prevalence of vaginal HPV infection among ever-married women. Method A descriptive cross-sectional study was carried ou...

Background Cervical cancer is the 2nd most common female cancer among Sri Lankan females and is almost associated with sexually transmitted cervicovaginal human papillomavirus (HPV) infection. The study objective is to determine the prevalence of vaginal HPV infection among ever-married women. Method A descriptive cross-sectional study was carried...

Introduction: Selenium (Se) may have a protective effect against some selected cancers. Ovarian cancer is ranked as one of the major killers of all gynecological malignancies worldwide. The objective of this study is to find the relationship between selenium intake and Epithelial Ovarian Cancer risk in women who have not had an oophorectomy.

Introduction: Selenium (Se) may have a protective effect against some selected cancers. Ovarian cancer is ranked as one of the major killers of all gynecological malignancies worldwide. The objective of this study is to find the relationship between selenium intake and Epithelial Ovarian Cancer risk in women who have not had an oophorectomy. Method...

Objective: Screening for cervical cancer in Sri Lankan females with Pap smears (conventional cytology) has shown no marked reduction in cervical cancer incidence over the past two decades. The study aims to compare the efficacy of Pap smear, with other screening tools such as Liquid Based Cytology (LBC) and Human Papilloma Virus/ deoxyribonucleic a...

A National Cancer Registry is an information system designed to collect, store, and manage data about cancer patients. Registries play a critical role in cancer surveillance and provide in efforts to reduce the cancer burden. Surveillance data can also be used for cancer research and to plan and evaluate cancer prevention and control interventions....

Prevalence and Associated Factors of Cervico vaginal HPV infection Among 35 Year Age Cohort Ever married Women in a District of SriLanka: a cross-sectional study

Acceptability, simplicity, and relevance of the new human papillomavirus/DNA test among 35-year-old eve married women in a district of Sri Lanka: focus group discussions Cervical cancer is the 2 nd leading cause of female cancer in Sri Lanka. Two major drawbacks of the present cervical cancer screening programme in Sri Lanka are, the suboptimal sen...

Long talk (8min) about The Feasibility of a new HPV/DNA test implementation as a primary cervical cancer screening method among 35- years old ever-married women in a district of SriLanka; A cross-sectional study

Protocol registered on Prospero for Systematic Review and Meta-analysis titled "Comprehensive Systematic Review and Meta-Analysis of the association between Selenium and Epithelial Ovarian Cancer (EOC) among women"

Background Two major drawbacks of the present cervical cancer screening programme in Sri Lanka are, the suboptimal sensitivity of the pap smear and the low coverage. The sensitivity of the HPV/DNA screening test is high. The objective of the study was to explore the acceptability relevance and simplicity of the new HPV/DNA screening implementation...

Background: One major drawback of the present National Cervical Cancer Screening programme is, the suboptimal sensitivity (53%) of the pap smear to detect Cervical Intraepithelial Neoplasia (CIN). HPV/DNA test is highly sensitive (92.9%) for CIN II viral load and the feasibility of HPV/DNA screening with conventional cytology for screen positive fo...

It is proven that the benefits of the vaccine for people with chronic kidney disease at any stage, those on dialysis, and post kidney transplant recipients are much greater than the risk of serious disease or complications from COVID-19. Patients with kidney diseases should be prioritized for COVID-19 vaccination and the available data suggest that...

Cancer patients given a single coronavirus vaccine develop significantly inferior protection against the illness than those who receive a booster shot, according to a UK study that called for a reassessment of the gap between jabs for vulnerable individuals. A new study revealed that Covishield, the vaccine against coronavirus, has an 81.3 percent...

Background: Even after 20 years of existence of the cervical cancer programme with pap smears, there is no marked reduction in the incidence of cervical cancer in Sri Lanka. Therefore, the cervical cancer screening programme needs to be reviewed again. Objective: To explore the perceptions of cervical cancer screening programme among health care wo...

Background: Cervical cancer is the second commonest among the Sri Lankan females which accounts for nearly 10% of all female cancers. Almost all cervical cancers are associated with Human Papilloma Virus (HPV) infection which is essentially sexually transmitted. If HPV infection persists in a woman, it may take up to 20 to 30 years to develop preca...

Background Cervical cancer is the second commonest female cancer in Sri Lanka and the National Cervical Cancer Screening methodis conventional cytology (sensitivity 53%) since 1998. All cervical cancers are associated with Human papillomavirus infection (HPV), and HPV genotypes 16 and 18 contributes for 70% of all cervical cancers. Other high risk...

Background: Cervical cancer is the 2nd leading cause of female cancer in Sri Lanka. All cervical cancers are virtually associated with human papillomavirus infection. HPV/DNA screening test is highly sensitive for high risk types of HPV (sensitivity 82%-100%). Therefore it’s important to find acceptability, relevance and simplicity of new HPV/DNA t...

Background: HPV/DNA test is highly sensitiveve (92.9%) for Cervical Intraepithelial Neoplasia (CIN) II viral load. The sensitivity of conventional cytology is 53%, while the Liquid Based Cytology (LBC) to detect CIN II+ is 79.1%. The objective of this study to describe the results of LBC vs. conventional cytology among HPV/DNA screen positives of 3...

Background: Cervical cancer is the 2nd leading cause of female cancer in Sri Lanka and annually 1721 new cases of cervical cancers are diagnosed and 690 women die from the disease, according to the 2012 estimates. Cervical cancers are virtually associated with sexually transmitted human papilloma virus (HPV) infection. Persistent infection with car...

Background Childhood obesity increases the risk of obesity in adulthood and is associated with cardiovascular disease risk factors. The roots of the obesity epidemic need to be tracked back as early in life as possible. Objective of the study was to determine the prevalence of obesity and to describe the association of overweight with selected fac...

Background: Persistent HPV infection with high risk oncogenic HPV genotypes can cause cervical cancer within 10-15 years, with a progression rate of 10%. Genotypes 16 and 18 contribute to about 70% of all cervical cancers worldwide. Other high-risk types are genotypes 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. One major drawback of the pre...

Background: Cervical cancer is the 2nd leading cause of female cancer in Sri Lanka. Hence, in 1998, Sri Lanka took the initiative to include screening for cervical cancer with conventional papaniculaou (pap) smear in the Well Woman Clinics. However, even after 20 years of cervical cancer screening (with pap smears), there is no marked reduction in...

Background: Persistent HPV infection with high risk oncogenic HPV genotypes can cause cervical cancer within 10-15 years, with a progression rate of 10%. Genotypes 16 and 18 contribute to about 70% of all cervical cancers worldwide. Other high-risk types are genotypes 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. One major drawback of the pre...

Background: Currently, pap smears are used to screen cervical cancers in Sri Lanka. Two major drawbacks of pap smear screening method are the suboptimal sensitivity and the low coverage. HPV/DNA screening method can be used as a cervical cancer screening method and high sensitivity (92.9%) is the major advantage of it. Specimens can be collected fo...

Background: Cervical cancer is the 2nd leading cause of female cancer in Sri Lanka and annually thousand seven hundred and twenty one new cases of cervical cancers are diagnosed and 690 women are died from the disease, according to 2012 estimates. Even after 20 years of cervical cancer screening (with pap smears), there is no marked reduction in in...

Background: Cervical cancer is the 2nd leading cause of female cancer in Sri Lanka. Hence, in 1998, Sri Lanka took the initiative to include screening for cervical cancer with conventional papaniculaou (pap) smear in the Well Woman Clinics. However, even after 20 years of cervical cancer screening (with pap smears), there is no marked reduction in...

Background: Even after 20 years of cervical cancer screening with pap smears, there is no marked reduction in incidence, morbidity and mortality of cervical cancer in Sri Lanka. Two major drawbacks of the present programme are the suboptimal sensitivity (53%) of the pap smear to detect Cervical Intraepithelial Neoplasia (CIN) and the low coverage....

Background: HPV/DNA screening test has an optimum sensitivity (92.9%) to detect cervical lesions. The objective of the study was to estimate the cost of cobas 4800 HPV/DNA test in thin prep cell collection media.

Background: HPV/DNA screening can be used as a primary cervical cancer screening method. The objective of the study was to describe colposcopy results of HPV/DNA screen positive women according to the Asia-Oceania guidelines of follow-up. Method: Descriptive longitudinal study was conducted from 1st of September 2018 to 28th of February 2020 from w...

Background Childhood obesity increases the risk of obesity in adulthood and is associated with cardiovascular disease risk factors. The roots of the obesity epidemic need to be tracked back as early in life as possible. The objective of the study was to determine the prevalence of obesity and to describe the association of overweight with selected...

Background One of the major drawback of the present cervical cancer screening programme in Sri Lankla is the suboptimal sensitivity (53%) of the pap smear to detect Cervical Intraepithelial Neoplasia (CIN). The sensitivity of LBC and HPV/DNA test to detect CIN II+ is 79.1% and 92.9% respectively. The objective of the study was to describe results o...

ISSN 2522-9400 European Modern Studies Journal Vol 5 No 1available at journal-ems.com73 European Modern Studies Journal, 2021, 5(2) Perception of Cervical Cancer Screening Program among Healthcare Workers in a District of Sri Lanka: A Qualitative Study[1]Perera, K.C.M., [2] Abeysena, H.T.C.S., [3] Mapitigama, N.[1]Directorate of Non-Communicable D...

Background Cervical cancer is the second commonest female cancer in Sri Lanka. Two major drawbacks of the present cervical cancer screening programme are the suboptimal sensitivity of the pap smear and the low coverage. The objective of the study is to determine the feasibility of a new HPV/DNA test among 35 -years -old ever-married women in a dist...

Burden of NCDs in Sri Lanka has gradually risen. Estimates have shown that NCDs were responsible for 83% of deaths in the country in 2016 (1). Coronavirus disease 2019 (COVID-19) has disrupted health services and has given rise to shortages of medicines across the globe (2). During March 2020, when the Sri Lankan government enforced curfew and quar...

Background: In 1998, conventional papanic0laou smear screening was included in the Well Woman Clinic (WWC) program as a cervical cancer screening method. The objective of the study was to explore the perception of cervical cancer screening programs among healthcare workers in a district of Sri Lanka.

Background: Discontinuation of medicines may lead to serious complications of NCD putting the patients in danger and causing an additional burden for the health system. Ministry of Health (MoH) introduced a mechanism to deliver medicines to the doorstep of people with NCDs who could afford to buy medicines from the state (Osusala) and private pharm...