Chithra PiyadasaUniversity of Manitoba | UMN · Department of Electrical and Computer Engineering
Chithra Piyadasa
Ph.D.
About
19
Publications
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119
Citations
Introduction
Additional affiliations
Education
January 1993 - December 2000
Uppsala University/Colomo University
Field of study
- Matrix assisted laser desorption time of flight mass spectrometry techniquies and its applications
Publications
Publications (19)
Laboratory experiments and natural phenomena investigations in this research series experimentally revealed the existence of gravitational repulsion force dependent on thermal energy content, pervading our surroundings both microscopically and macroscopically. This paper presents an alternative mathematical model of both gravitational repulsion and...
The objective of this study is to propose a heuristic model of energy propagation due to an anomaly; electromagnetic (EM) field penetration into a continuously covered conducting enclosure (Faraday shield) from an external radio frequency source, violating the accepted model in the EM field theory. In this study, at an arbitrarily selected frequenc...
The gravitational attraction force being proportional to the mass has been experimentally shown for several hundred years now, but no gravitational repulsion has been identified within the accepted scientific reasoning. Here, we show that the gravitational repulsion force, similar to the gravitational attraction among particles has also been in exi...
The general belief is that the gravitational force is always attractive and no repulsive force could result. This is contrary to properties of electric and magnetic forces. These two forces can cause in both attraction and repulsion, depending on the situation. However, the investigation set forth here on the movement of liquid water droplets in st...
Attempts to explain the redistribution of energy in interference has been done from time to time, under
two of the most accepted theories, wave and quantum; however its mechanism still lacks clear interpretation.
In this study, a new experiment has been designed and conducted to observe the redistributed energy
in wave interference. Experimental ob...
The paper shows that the boundary diffraction wave originating at an edge is an omnidirectional cylindrical wave. The experimental set-up used to demonstrate this property employs a He–Ne laser beam. The beam is split into three beams using a glass plate. One of the beams passes straight through, the second beam passes through the glass plate and t...
The movement of liquid water droplets against the gravitational field has been shown. This was observed when
projecting condensed steam droplets downwards. The observations show that the droplets decelerated and turned around
at a point with their velocity becoming zero and begin moving upwards against the earth’s gravitational attraction.
Further...
Experimental evidence of the existence of the boundary diffraction wave is presented. The
secondary wave occurring at the boundary of a sharp knife edge, interacts with each other
while crosses the primary wave. This interaction and its path have been experimentally
observed and recorded using a CCD sensor array. The observed diffraction profile of...
Particles which undergo a change of state or phase transition to gaseous form by acquiring latent heat have shown a
movement against the gravitational field. In this regard, upward mobility of iodine molecules under different conditions
and geometries has been studied. No adequate explanation to this observation can be given with conventional laws...
The analyte distributions in matrix-assisted laser desorption/ionization (MALDI) samples have been studied using MALDI imaging at better than 10 μm spatial resolution in an orthogonal-injection TOF instrument. The technique is demonstrated by mapping the analyte distribution in typical preparations of MALDI samples using the common matrices 2,5-dih...
A matrix assisted laser desorption/ionization time-of-flight mass spectrometer has been built with an ion source that can be operated in either constant-energy or constant-momentum acceleration modes. A decreasing electric field distribution in the ion-accelerating region makes it possible to direct ions onto a space-focal plane in either modes of...
One of the well-known effects of electromagnetic waves is interference. Redistribution of
energy in interference is well documented in literature but the mechanism has not been
discussed in detail. A set of new experiments has been designed and conducted to observe the
actual redistribution of the energy of the electromagnetic waves while being int...
The efficiency of high m/z detectors has been extensively studied since the introduction of MALDI. These detectors are mainly based on secondary ion or secondary electron emission. An important difficulty in many of the measurements has been the interpretation of the analog signal produced by a plume of ions from a single MALDI event. The introduct...
The high sensitivity available with MALDI has given rise to a growing interest in producing molecular images of biological tissue. Considerable progress has been made by Caprioli's group at Vanderbilt using mainly commercial, axial-injection MALDI TOF instruments. Spatial resolution is typically 25 to 200 µm, limited by the laser spot size possible...
Two electrostatic mirrors, mounted symmetrically on the same optical axis facing each other, are used to increase the time-of-flight of molecular ions produced in matrix-assisted laser desorption/ionization (MALDI). The mirrors, which are used in the non-compensating mode, are located between a MALDI ion source and a stop detector. The source is op...
An electrostatic deflector has been designed and constructed that can be used in a reflecting time-of-flight mass spectrometer for either single-deflector or dual-deflector velocity selection in post-source decay measurements. The deflector consists of an interleaved set of parallel deflection electrodes as in a Loeb/Cravath/Bradbury device, but th...