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Citations since 2016
1 Research Item
Background: Free radicals are involved in pathophysiology directly and indirectly in sepsis or endotoxemia. Obstructive jaundice may promote bacterial overgrowth with resultant endotoxemia or sepsis. The purposes of the studies are to test the protective effect of free radical scavenger in obstructive jaundice. Materials and methods: Male Sprague-D...
Translocation of bacteria and endotoxtin has long been documented in obstructive jaundice, and altered intestinal barrier function is considered to be one of the important mechanisms for this phenomenon. The regulation of gastrointestinal mucosal response to injury is thus of important clinical as well as biological relevance. Integrins play a crit...
There is a high incidence of perioperative morbidity and mortality in patients with obstructive jaundice due to sepsis. Tumor necrosis factor-a (TNF-alpha) is considered a crucial mediator in inducing and processing the inflammatory cascade. We hypothesize that obstructive jaundice leads to an increased endotoxin-induced TNF-alpha production and th...
Matrix metalloproteinases (MMPs) have been reported to be associated with invasive and metastatic behaviors of human malignant tumors. However, there is still limited knowledge about the role of matrix metalloproteinases-2 (MMP-2) in breast cancer. This study was designed with the aim to elucidate the possible relationship between the preoperative...
The outcome of breast carcinoma is usually determined by multiple factors. Aberrant expression of the cell adhesion molecule CD 44 has been claimed to be associated with poor prognosis in various human malignancies. This study was designed to investigate any correlation between the soluble adhesion molecule CD 44 and the clinicopathologic variables...
Two cases of primary malignant lymphoma of the breast were found, with breast cancer as the provisional clinical diagnosis for these two cases. Estrogen receptor determination via monoclonal antibody technology was performed in one case and the result was negative. Frozen section examination of another case during operation revealed chronic inflamm...