Chigozie Anarado

• Nnamdi Azikiwe University

The emergence of the industrial revolution has led to an enormous increase in heavy metal pollution of the biosphere which subsequently became a threat to the environment and human life. Heavy metal pollution has been recognised as one of the most critical threats to soil and water resources, together with human health. The potential of Jatropha cu...

A dione ligand, 1,1′-(piperazine-1,4-diyl)bis(2-phenylethan-1-one) derived from the reaction of phenylacetylchloride with piperazine and the lanthanides, Ce(III), Nd(III), and Pr(III) complexes of general formula [LnL(NO3)2]NO3 were synthesized. The compounds were characterized by conventional NMR, Mass, and Infra-Red UV-vis spectroscopic technique...

4-Tert-butylbenzohydrazone ligand was synthesised by reacting 4-tert-butylbenzohydrazide with dehydroacetic acid. Afterward, the Cu(II), Ni(II), Co(II), and Mn(II) complexes of 4-tert-butylbenzohydrazone were synthesised. All the synthesised compounds were characterised using elemental analysis, ESI-MS, IR, 1H-NMR and 13C-NMR spectroscopic methods....

Clarias gariepinus and Oreochromis niloticus are two important fish species that are widely consumed in many parts of the world. This study investigated the nutritional composition, fatty acid profiles and organoleptic evaluation of these two fish species raised under wild and pond-cultured systems. Five samples each of the species were randomly co...

Antimicrobial and anticancer activities against prostate (PC-3) and breast (MCF-7) cancer cells by Schiff base derived from novel 4-Nitrobenzohydrazone ligand and its Cu(II), Ni(II), Co(II), and Mn(II) complexes are reported in this study. Characterizations by conventional spectroscopic techniques and elemental analyses suggest successful syntheses...

Xylooligosaccharides derived from Xylan, significant component of hemicellulose in lignocellulosic plant biomass, are essential raw materials used in the food, pharmaceutical and agricultural industries. They find application in these industries due to their unique physicochemical properties such as pH stability, growth regulatory ability, and anti...

Diabetes Mellitus is a systemic metabolic disorder caused by relative or absolute insulin secretion deficiency or resistance, characterized by hyperglycemia. It has affected 5% of the world’s population and accounts for about 10 % of total health care expenditure in many countries. The present investigation was carried out to explore the proximate,...

Background: Combretum platypterum is used ethno-medically in the treatment many diseases in Africa, such as; helminthiasis, sexually transmitted diseases, conjunctivitis, malaria, lumps, fever, eye problems, diarrhea, lower backache, coughs, swellings, as febrifuge, tonic, and to stop post-partum bleeding. Aim: This work was aimed at investigating...

Aim: To study the phytochemical, proximate, antimicrobial and anti-malarial activities of leaf extracts of Justicia carnea Methods: The leaf sample of Justicia carnea which has been used in Nigeria folklore in treating malaria, cancer and many other diseases was extracted with methanol, ethyl acetate and n-hexane. The extracts were subjected to qua...

Despite several studies towards anti-HIV therapy, HIV infections remain a challenge due to the resistivity of developed drugs. The emergence of new HIV-1 PR mutations has led to the drug resistance of the available FDA approved drugs and lower activity towards the HIV protease. Based on this the molecular properties of 4-hydroxy-6-methyl-3-[(1E)-1-...

Aim: Justicia carnea has been used in traditional medicine in Nigeria in the treatment and management of various diseases which include inflammation, cancer, malaria, sickle cell disease, gastrointestinal infections, anemia, HIV, diabetes, diarrhea, typhoid, liver diseases, hepatitis, cough, etc. This review is aimed at checking the relationship be...

Aim: To compare the phytochemicals and antimicrobial activities of Pterocarpus mildbraedii Harms and Xylopia aethiopica(Dual) A.Rich Methodology: The leaves of P. mildbraedii and X. aethiopica were collected, washed, air-dried, ground and each extracted with n-hexane, ethyl acetate and methanol. The extracts were analysed for the presence of phytoc...

Fertilizer application has gained much attention because not only has it been increasing crop yield (improving the economy of the farmers), but also been increasing/decreasing heavy metals uptake by many plants. In this study, four non-edible African plants-Euphorbia heterophylla, Axonopus compressus, Emilia coccinea and Scoparia dulcis were used t...

Aim: To compare the phytochemicals and anti bacterial activities of leaf, stem and root extracts of Spathodea companulata. Methodology: The leaf, stem and root of Spathodea companulata were collected, washed, air-dried, ground and each extracted with water, methanol, ethyl acetate and n-hexane. The extracts were analysed for the presence of phytoch...

Aim: To compare the phytochemicals and antioxidant activities of stem bark and root extracts of Annona muricata. Methodology: The stem bark and root of Annona muricata were collected, washed, air-dried, ground and each extracted with methanol, ethyl acetate and n-hexane. The extracts were analysed for the presence of phytochemicals. Antioxidant scr...

This analysis was carried out to identify and compare the phytochemicals present in the n-hexane, methanol and ethyl acetate extracts of the leaves of Bridelia micrantha, Cassytha filiformis, Euphorbia hirta and Securinega virosa and their antimicrobial activities. The results showed presence of saponin, flavonoids, alkaloids, tannin and phenolics...

The major deposits of Kaolinitic mineral were sampled, with the aim of studying possible solid solution, ionic substitution, and thus, ultimately understanding the the nature and sizes of nanoparticles in the mineral deposits. Powder X-ray Diffraction Analysis, X-ray Flourescence analysis and Physical tests were used to study them. Kaolinite and Qu...

Public pipe-borne water system had collapsed in Anambra state of Nigeria, for over fifteen years, challenging the residents of the state to resort to alternative sources of potable water, notably, boreholes. It is imperative to continuously assess the quality of the water. In this work, two boreholes each in nineteen communities, one from Aguluzigb...

Homoleptic Co(II), Cu(II) and Ni(II) complexes of a hydrazone derived from 3‐acetyl‐2‐hydroxy‐6‐methyl‐4H‐pyran‐4‐one (dehydroacetic acid) and 2‐furoic acid hydrazide, and their heteroleptic analogues with 2,2′‐bipyridine were synthesized. The complexes were characterized by spectroscopic methods (ESI‐MS, IR and NMR), elemental analysis, magnetic s...

Iodine Deficiency Diseases (IDDs) occupy important positions in the health problems of developing countries. Salt Iodisation has been the common approach to solving these problems. However, apart from the problems of lack of compliance by salt manufacturers, and inculturation of the consumers, health conditions aggravated by high salt intake by hum...

Co(II), Ni(II) and Cu(II) complexes of a benzohydrazone derivative, obtained by the reaction of dehydroacetic acid and benzohydrazide, have been synthesized and characterized by conventional spectroscopic techniques, elemental analyses, magnetic susceptibility and conductivity methods, and screened for antibacterial, DNA binding and cleavage proper...

A novel hydrazone ligand derived from condensation reaction of 3-hydroxy-2-naphthoic hydrazide and dehydroacetic acid, and its Ni(II), Cu(II) and Co(II) complexes were synthesized, characterized by spectroscopic, elemental analyses, magnetic susceptibility and conductivity methods, and screened for antimicrobial, DNA binding and cleavage properties...

Recently pollution of the environment has gathered an increased global interest. In this respect, contamination of soils with heavy metals has always been considered a critical challenge in the scientific community . Remediation of soil contaminated by heavy metals is necessary in order to reduce the associated risks, make the land resource availab...

The effect of anthropogenic activity relating to industrial and economic development has had a detrimental impact on the environment and human health, and hence the need for continued research. Five common African vegetables—Murraya koenigii , Ocimum gratissimum, Amaranthus hybridus , Capsicum annuum and Moringa oleifera were used to study absorpti...

Solving the problem of heavy metal pollution and its effects on the biota have remained a frontline issue in the public health matters of developing , and even the developed countries. Non-edible African plants-Dieffenbachia bownanii and Eleusine indica-were used to study the absorption of Cadmium, Lead Zinc and Cobalt from soils inoculated with th...

he phytoremediating capacities of Telfaira occidentalis, Bryophyllum pinnatum, Talinum triiangulare, Vigna unguiculata, for metal ions, were studied. Soil samples, tested for Cobalt, lead and Zinc ions concentration levels were inoculatedwith 0.1M solution of Co(NO 3) 2 , Pb(NO 3) 2 and Zn(NO 3) 2 before planting the above species. The roots, stems...

In this study, the combined effect of the Atlantic Multidecadal Oscillation (AMO) and El Niño Southern Oscillation (ENSO) on the Lake Chad (LC) level variability is explored. Our results show that the lake level at the Bol monitoring station has a statistically significant correlation with precipitation (R2 = 0.6, at the 99.5% confidence level). Th...

A research was conducted to verify the degree of partitioning of some selected trace metals in the soil sediment collected from floodplain soil in Onitsha, Anambra State, Nigeria. The investigation was carried out using standard method in accordance with the modified Horowitz et al procedure of trace metals speciation. Lead had the highest total fr...