Chia-Hsien Chen

Chia-Hsien Chen
Taipei Medical University | TMU · Department of Orthopedics

About

28
Publications
4,460
Reads
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304
Citations
Citations since 2016
20 Research Items
292 Citations
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2016201720182019202020212022020406080
2016201720182019202020212022020406080
2016201720182019202020212022020406080

Publications

Publications (28)
Article
Full-text available
The main causes for failure in implant surgery are prolonged exposure of implants or wound and tissue ischemia. Bacterial infection caused by the surrounding medical environment and equipment is also a major risk factor. The medical risk would be greatly reduced if we could develop an implant coating to guide tissue growth and promote antibacterial...
Article
Full-text available
Suture anchor fixation is a common method for securing bone and soft tissue in the body, with proven applications in the hip, elbow, hand, knee and foot. A critical limiting factor of suture anchors is the pull-out strength, particularly in suboptimal bone. This study introduces a novel 3D printed threadless suture anchor with a rectangular cross-s...
Preprint
Full-text available
Background Achilles tendon rupture remains one of the most common tendon injuries in adult population. At present, randomized studies have failed to demonstrate the optimal management of Achilles tendon rupture. Wound complications have been significantly minimized since the emergence of percutaneous repairs when compared to traditional open method...
Article
Full-text available
This study proposed a pedicle screw design where the proximal 1/3 of the screw is unthreaded to improve fixation in posterior spinal surgery. This design was also expected to reduce the incidence of mechanical failure often observed when an unsupported screw length is exposed outside the vertebra in deformed or degenerated segments. The aim of this...
Article
Background The TomoFix plate has been extensively used in high tibial osteotomy surgery to stabilize the distracted tibial bones. However, distal pain related to plate irritation was considered one of the most relevant complications for this fixation device. This study aimed to correlate reports of distal pain with the profiles of the distracted ti...
Article
Full-text available
A hybrid fixation method, using a combination of vertebroplasty and cement-augmented screws, has been demonstrated as a useful technique for securing osteoporotic burst fractures. The purpose of this study was to assess changes in the range of motion (ROM) and stress in the spine after treating a lumbar burst fracture with this hybrid method. Five...
Article
Full-text available
Background: Lumbar spinal fusion with rigid spinal fixators as one of the high risk factors related to adjacent-segment failure. The purpose of this study is to investigate how the material properties of spinal fixation rods influence the biomechanical behavior at the instrumented and adjacent levels through the use of the finite element method....
Article
Full-text available
Pedicle screws are commonly used for posterior stabilization of the spine. When used in deformed or degenerated segments, the pedicle screws are often not fully inserted into the bone, but instead the threaded portion is exposed by 1 or 2 threads to accommodate rod placement and ensure alignment between the tulip of the screw and the rod. However,...
Article
Full-text available
Background: Effective treatment of low back pain (LBP) originating in the lumbar and sacroiliac joints is difficult to achieve. The objective of the current study was to compare the clinical effectiveness of radiofrequency (RF) neurotomy versus conservative nonsurgical approaches for the management of chronic lumbar and sacroiliac joint pain. Met...
Article
Full-text available
The majority of compressive vertebral fractures in osteoporotic bone occur at the level of the thoracolumbar junction. Immediate decompression is often required in order to reduce the extent of neurological damage. This study evaluated four fixation methods for decompression in patients with thoracolumbar burst fractures, and presented the most sui...
Article
Full-text available
Background Estrogen deficiency is associated with musculoskeletal disorders. Sintered dicalcium pyrophosphate (SDCP) is a novel antiosteoporotic agent. In this study, we examined its use for restoration of bone quality and attenuation of disc degeneration in ovariectomy rats. Methods Sixty female Sprague Dawley rats were randomly divided into 3 gr...
Article
Full-text available
Background and objectives: This study is a meta-analysis of randomized controlled trials comparing the efficacy of transcutaneous electrical nerve stimulation (TENS) to a control and to other nerve stimulation therapies (NSTs) for the treatment of chronic back pain. Methods: Citations were identified in MEDLINE, the Cochrane Library, Google Scho...
Article
Full-text available
Interbody fusion with posterior instrumentation is a common method for treating lumbar degenerative disc diseases. However, the high rigidity of the fusion construct may produce abnormal stresses at the adjacent segment and lead to adjacent segment degeneration (ASD). As such, biodegradable implants are becoming more popular for use in orthopaedic...
Article
Full-text available
Recent advances in tissue engineering have led to potential new strategies, especially decellularization protocols from natural tissues, for the repair, replacement, and regeneration of intervertebral discs. This study aimed to validate our previously reported method for the decellularization of annulus fibrosus (AF) tissue and to quantify potentia...
Article
Full-text available
Background context: Minimally invasive spine surgery has become increasingly popular in clinical practice, and it offers patients the potential benefits of reduced blood loss, wound pain, and infection risk, and it also diminishes the loss of working time and length of hospital stay. However, surgeons require more intraoperative fluoroscopy and io...
Article
Full-text available
Background data: Combined usage of posterior lumbar interbody fusion and transpedicular fixation has been extensively used to treat the various lumbar degenerative disc diseases. The transpedicular fixator aims to increase stability and enhance the fusion rate. However, how the fused disc and bridged vertebrae respectively affect adjacent-segment...
Article
Several plate systems for high tibial osteotomy (HTO) have been developed to stabilize the opening wedge of an osteotomized tibia. Among them, the TomoFix system, having a quasi-straight and T-shaped design, has been widely adopted in the literature. However, this system is implemented by inserting a lag (i.e., cortical) screw through the proximal...
Article
Full-text available
Background: Failure of pedicle screw is a major concern in spinal surgery. The threaded and unthreaded portions of the pedicle screw provide the ability to anchor and squeeze the surrounding bone, respectively. This study aimed to investigate the anchoring and squeezing effects of different design of the threaded/unthreaded portions of a pedicle s...
Article
Full-text available
Purpose The purpose was to quantify the structural integrity of annulus fibrosis (AF) after injuries with repair. Methods Punctures in the AF of 6-month-old porcine spine specimens were made with 18-, 20-, 22-, 24-, and 26-gauge needles. Leakage testing was performed immediately after needle puncture (Group 1), after the puncture was repaired with...
Article
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Honokiol is a potential candidate for the treatment of intervertebral disc (IVD) degeneration. In this study, we develop in vitro and in vivo methods to detect the distribution of honokiol in intervertebral discs using high-performance liquid chromatography. A rat tail disc was used for both experimental models. For the in vivo animal experiment, b...
Article
Femoral nerve palsy due to iliacus hematoma has been reported previously1-4. Its incidence has increased because of the widespread use of anticoagulants and revision hip surgery. Surgical hematoma evacuation has been highly recommended in patients with coagulopathy5. In healthy patients with posttraumatic iliacus hematoma, previous case reports hav...
Article
Full-text available
The aim of this study was to evaluate the effect of sintered dicalcium pyrophosphate (SDCP) on fracture healing in an osteoporotic rat model. Female Sprague-Dawley rats (8 weeks old) were randomly allocated into five groups: sham-operated group, and bilateral ovariectomized group treated with SDCP, alendronate, calcitonin, or no treatment. Rats wer...
Article
Calcium phosphate ceramic has been known for its properties of bioactivity and osteoconductivity and has been widely used in orthopedic, plastic and craniofacial surgeries. The biocompatibility, unlimited availability, lower morbidity for the patient and cost-effectiveness of calcium phosphate ceramics represent important advantages over other biol...
Article
Full-text available
Introduction: Treatment for osteoporosis commonly includes the use of bisphosphonates. Serious side effects of these drugs are caused by the inhibition of bone resorption as a result of osteoclast apoptosis. Treatment using calcitonin along with bisphosphonates overcomes these side-effects in some patients. Calcitonin is known to inhibit bone reso...
Article
IntroductionStandard techniques for lumbar decompression, fusion, and pedicle screw fixation involve open exposures, extensive muscle dissection, and posterior element destruction. The purpose of this study was to report the initial clinical experience with minimally invasive decompression, transforaminal interbody fusion, and percutaneous pedicle...
Article
Autogenous bone grafting is still the gold standard for use in bone defects in orthopedic, plastic, and craniofacial surgeries. However, some patients are unable to provide sufficient quantity of bone and the high postoperative morbidity limits its clinical use. Currently, various bone substitutes are available for clinical applications, including...

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