Cheng-Chen Hsu

Taipei Medical University | TMU · Department of Anatomy and Cell Biology

Exercise-induced muscle damage (EIMD) is characterized by a reduction in functional performance, disruption of muscle structure, production of reactive oxygen species, and inflammatory reactions. Ginseng, along with its major bioactive component ginsenosides, has been widely employed in traditional Chinese medicine. The protective potential of Amer...

Electrospun polyacrylonitrile fiber membranes (EPFMs) were coated with multilayer films, assembled using the layer-by-layer (LbL) technique through the alternate deposition of poly(allylamine hydrochloride) (PAH) and poly(acrylic acid) (PAA), to develop an antithrombogenic drug release membrane for hemodialysis. Methylene blue (MB) and heparin (HEP...

Several studies have compared molecular components between red and white skeletal muscles in mammals. However, mammalian skeletal muscles are composed of mixed types of muscle fibers. In the current study, we analyzed and compared the distributions of titin, lipid, phosphate ions, and fatty acid levels in red and white muscles using a fish model (...

A recent study reported that lower limb explosive power had no correlation with the 2D:4D ratio. However, many studies hypothesized that a lower 2D:4D ratio (reflecting a relative higher testosterone exposure) predicts higher physical fitness. The aim of this study is to replicate the study of explosive power and the 2D:4D ratio in a sample of Taiw...

In this study we used the poly(N-isopropylacrylamide) (PNIPAAm) as a medium to blend with a organic DNA, herring sperm DNA (HSD), to generate PNIPAAm-HSD supramolecular complexes. Bio-multiple hydrogen bonding (BMHB) between PNIPAAm and HSD was investigated that changed the temperature responsiveness of PNIPAAm relatively to the HSD concentrations....

The ratio of the length of the second finger (index finger) to the fourth finger (ring finger) (2D:4D ratio) is a putative marker for prenatal hormones. Physiological research has suggested a low 2D:4D ratio correlates with high athletic ability. Athletes of specific sports (e.g., American football) have lower 2D:4D ratios than those of nonathletes...

The ratio of the length of the second finger (index finger) to the fourth finger (ring finger) (2D:4D ratio) is a putative marker for prenatal hormones. Physiological research has suggested a low 2D:4D ratio correlates with high athletic ability. Athletes of specific sports (e.g., American football) have lower 2D:4D ratios than those of nonathletes...

Background Angelica Sinensis (AS), a folk medicine, has long been used in ergogenic aids for athletes, but there is little scientific evidence supporting its effects. We investigated whether AS induces hypertrophy in myotubes through the phosphatidylinositol 3-kinase (PI3K)/Akt (also termed PKB)/mammalian target of the rapamycin (mTOR) pathway. Me...

Lipid metabolism in visceral fat cells is correlated with metabolic syndrome and cardiovascular diseases. Okadaic-acid, a 38-carbon fatty acid isolated from the black sponge Halichondria okadai, can stimulate lipolysis by promoting the phosphorylation of several proteins in adipocytes. However, the mechanism of okadaic acid-induced lipolysis and th...

The American ginseng (Panax quinquefolium L.) is widely used in the oriental traditional medicine. The present study investigates the protection effects of Panax quinquefolium extract granule (PQEG) against chemical-induced gastric mucosal injury. In vitro cell damage was induced by incubating rat gastric mucosal cells, RGM1, with indomethacin (IND...

This study investigated satellite cells and their related molecular events adapted to light moderate endurance training in the white gastrocnemius muscle of the rat. The white gastrocnemius muscle of male Sprague-Dawley rats that had been trained for 4 weeks and 8 weeks, with control rats being analysed alongside them, was selected for analysis (n=...

The purpose of this study was to assess the effects of oral Cordyceps sinensis supplementation combined with resistance training in young male adults. A group of 16 subjects were randomly allocated to two groups (double blind) to receive either Cordyceps sinensis (CS; 2.4 g/day; n = 8) or a placebo (P; 2.4 g maltodextrin/day; n = 8) during eight we...

This study investigated the effects of BCAA, arginine and carbohydrate combined beverage (BCAA Drink) on biochemical responses and psychological conditions during recovery after a single bout of exhaustive exercise. Fourteen healthy males were assigned to drink either BCAA Drink (BA trial) or placebo (PL trial) on two sessions separated by 2 weeks....

Purpose: This study aimed to investigate the effect of moderate endurance training on cardio-protective molecule adaptations, including marker of stem cell activation in the myocardium. Materials and Methods: Twenty-four Spra-gue-Dawley rats were randomly divided into a 4-wk exercise training (4WT) group, a 4-wk sedentary control (4WC) group, an 8-...

Background and Puepose: The molecular pathological markers of vascular endothelial growth factor (VEGF), hypoxia inducible factor-1 alpha (HIF-1α), von Hippel-Lindau tumor suppressor protein (VHL) and peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC- 1α), are recently linked in the regulation of oxygen availability. The pur...

We compared the lower limb muscle activation during uphill running (UR), level running (LR), and downhill running (DR). Eight male physically active subjects ran three slopes for 30 min at the given speed (55% vVO2peak at LR), including DR (-6°), LR (0°), and UR (6°) in a random crossover, repeated measures design. Electromyographic (EMG) signals w...

To investigate whether American ginseng (AG, Panax quinquefolium) supplementation was able to improve endurance exercise performance. Thirteen physically active male college students were divided into two groups (AG or placebo) and received supplementation for 4 wk, before the exhaustive running exercise. Treadmill speed was increased to a pace equ...

This study aims to understand the effect of ten-week passive repetitive plyometric (PRP) training on human skeletal muscle and the application of PRP training for performance. Vastus lateralis of nine candidates were aspirated before (pre) and after (post) PRP training. Histochemical approaches with regular hematoxylene-eosin (HE) and Mallory's pho...

To investigate whether exogenous surfactant would improve gas exchange and lung histology and methylprednisolone pretreatment would enhance the surfactant effect in a rat model of paraquat-induced lung injury. University research facility. Thirty-three adult male Sprague-Dawley rats. All rats received intraperitoneal paraquat injection (35 mg/kg) a...