• Home
  • Chellaram Chinnachamy
Chellaram Chinnachamy

Chellaram Chinnachamy
University of Technlogy and Applied Sciences Sultanate of Oman · Applied Biotechnology

Ph.D

About

139
Publications
52,174
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
977
Citations
Additional affiliations
September 2015 - January 2021
University of Technology and Applied Sciences, Sur, Sultanate of Oman
Position
  • Professor (Assistant)
February 2010 - July 2015
Vel Tech Multi Tech Dr. Rangarajan Dr. Sakunthala Engineering College
Position
  • HOD Cum Associate Professor
April 2008 - January 2010
Vel Tech Multi Tech Dr.RR Dr.SR Engineering College
Position
  • Research Assistant
Description
  • ..
Education
April 2008 - March 2010
July 2002 - March 2007
Manonmaniam Sundaranar University
Field of study
  • Biotechnology
June 1999 - April 2011
Periyar University
Field of study
  • Biotechnology

Publications

Publications (139)
Article
Full-text available
Objective: The objective of this study was to find the potency and bioefficacy of Asiatic acid and triterpene against four different plant fungal pathogens using a structure-based drug designing approach. Methods: The pathogenic fungus which causes a dreadful effect on plants is reviewed from literature study, and its three-dimensional structures a...
Article
Marine environment continues to be a huge source of pharmacologically active compounds that cure deadly disease. This research investigates the bioactive efficacy of bacteria isolated from surface of the coral, Junceella juncea (Pallas, 1766). 128 bacterial strains were isolated from the coral Junceella juncea from Tuticorin coast, Gulf of Mannar r...
Article
Full-text available
Plant based drugs got very important place in the modern society, this is due to the low cost, no side effects and the availability of natural chemical constituents formed during the metabolic pathway of plants. Among the herbal plants, Salacia oblonga is an important valuable traditional Ayurveda plant belonging to the family of Celastraceae. It i...
Article
Full-text available
Our present investigation deals with the phytochemical screening, estimation of total flavonoids, terpenoids and tannin contents to evaluate the anti-diabetic activities of Salacia oblonga stem followed by GC-MS analysis. It explores the natural compounds and the potential α-amylase and α-glucosidase inhibitory actions of stem extracts. The aqueous...
Article
The aim of the present study was to investigate the phytochemical screening, anti-inflammatory activity from the leaf of Borreria hispida by membrane stabilization test. The leaves were collected from different regions of Tamil Nadu. The leaf extracts of Borreria hispida from five different solvents were investigated. The phytochemical analysis rev...
Article
The present investigation was carried out to quantify the phytochemical constituents such as total flavonoid, total terpenoid and anti-inflammatory activity of aqueous stem extract of Salacia oblonga. Preliminary screening involved the qualitative methods to detect the availability of phenol, tannin, saponin, alkaloids, terpenoids, quinones, flavon...
Article
Objective: The aim of the present study was to evaluate the total content of phenol, terpenoid and flavonoids from leaf extract of Borreria hispida which was collected from Tamilnadu regions. The leaf extract was also evaluated for antioxidant activity and in vitro anti-inflammatory activity. Methods: In the present investigation, the best accessio...
Article
Objective: The present study was performed to investigate the phytochemical screening, antioxidant activity and antibacterial activity from the stem extract of Salacia oblonga (S. oblonga). Methods: The stem extracts were evaluated for antioxidant activities by DPPH (1, 1–Diphenyl-2-picryl-hydrazyl) radical scavenging assay. Different concentration...
Article
Objective: Aim of this study deals with screening and characterization of chitinase-producing bacteria from marine waste and its deposited soil along the coastal regions in Chennai. Methods: The soil samples were collected aseptically and subjected to serial dilution to isolate the bacterial strains. Totally, 35 morphologically different microorgan...
Article
The aim of the present work is to investigate bioactive metabolites from gut bacteria of short horned grasshoppers. In this present study the bacteria are isolated from the gut of short horned grasshoppers and screened for antagonistic activity. To test for antagonistic effect the gut isolated bacteria were tested against four human pathogenic bact...
Article
Aim of the research is to isolate and identify bacteria from sea fan corals and analyzing its insecticidal activity against storage pest, Sitophilus oryzae. The bacterial strain WP3, was isolated from the coral Junceella juncea from Tuticorin coast, Gulf of Mannar region, south east coast of India. Insecticidal activity of pure compounds was assaye...
Article
Currently, many researches has been carried to devise the navigation for blind people. Here, we propose an efficient system to aid the visually impaired in their navigation. User will be indicated about the nearing obustruction with closer ambiance. The basic concept behind this system is to detect the nearest hindarence through a stereoscopic sona...
Article
Objective: To screen and isolate peptide antibiotics producing epibiotic bacteria from the surface of the sea fan Juncella juncea, and partially purify the active compound. Methods: In this study, epibiotic bacteria were isolated by swabbing a small area of the coral surface with a sterile cotton swab, which was then directly swabbed on to Zobell m...
Article
The present study aims at investigating the phytochemical composition, tannin content and antibacterial activity of leaf extracts of Borreria hispida. Phytochemical screening of various extracts such as aqueous, ethanol, chloroform, acetone and petroleum ether of leaf extracts, revealed the presence of tannins, saponins, phenols, flavonoids, cardia...
Article
The study was conducted to determine the antioxidant activity, total phenol and flavonoid content of the stem of Salacia oblonga, collected from five geographically distant regions of Western Ghat, Karnataka were examined using extracts of aqueous, ethanol, methanol, chloroform and petroleum ether. The five different solvent extracts of S. oblonga...
Article
This research was undertaken to investigate the bioactive efficacy of bacteria isolated from surface of coral, Junceella juncea (Pallas, 1766). 164 bacterial strains were isolated from the coral Junceella juncea from Tuticorin coast, Gulf of Mannar region, south east coast of India. The strains were tested for antibiotic production against selected...
Research
Screening and isolation of bioactive epibiotic bacterial from gorgonian coral, Subergorgia suberosa from Gulf of Mannar, Southeast Coast of India. Antagonistic activity was performed by agar overlay method and phylogenetic characterization of the potential strain was carried out by comparative sequencing of 16s rRNA technique. The ethanol precipita...
Article
Bacteria are common populace of surfaces and the internal tissues of most plants. These bacteria contribute to the health, growth and development of plants. In this study, 45 strains were isolated from Phyllanthus niruri plant leaves. Phyllanthus niruri is a medicinal plant used popularly to cure jaundice. Endophytic bacteria isolated were tested a...
Article
Antagonistic activity was performed by agar overlay method and phylogenetic characterization of the potential strain was carried out by comparative sequencing of 16s rRNA technique. Ethanol precipitation of the strain has been analysis by Mass Spectrophotometry (MALDI-TOF). An epibiotic bacterial strain SGAA-2 was isolated from the gorgonian coral,...
Article
Purification of recombinant bacteriorhodopsin (BR) from E.coli was achieved by two step process that includes the expression of Bacterio-opsin (BO, apoprotein) and renaturation with retinol. However, the expression of BO in E.coli was hampered by the extensive cytoplasmic proteolytic degradation. The usage of N-terminal signal sequence particularly...
Article
Full-text available
The development of technology provides a new way in all areas of living. Agriculture is considered as the oldest area which is highly essential for life of earth. Agriculture plays a crucial role in the life of an economy. The importance of agriculture in a country is to provide a Source of Livelihood, Contribution to National Income, Supply of Foo...
Article
Marine organisms continue to be a huge source to produce unique and potential bioactive compounds that cure deadly disease. This research investigates the herbicidal properties of bacteria isolated from surface of the coral, Junceella juncea (Pallas, 1766). Two hundred and thirty four different bacterial strains were isolated from the coral from Tu...
Article
Seafood has been a popular food item and the main source of animal protein around the globe from time immemorial. The economic growth leads to the extensive demand of " ready-to-cook " or ready-to-serve products, which results in the development of 'convenience' products to meet out the need of the people. The diversified products using vegetables,...
Article
The increasing resistance of pathogens and the side effects of antibiotics have made it vital to find new alternative compounds from different sources. In the present study, the antibacterial potential of two green seaweeds was screened against 10 human pathogenic bacteria. The seaweeds were extracted with Acetone, Petroleum ether and Methanol and...
Article
Magical spell have the ability to turn everything touched into gold, in real time scenario one such spell is “Nanotechnology” which has the mysterical power to revolutionize every field touched by it. Nanotechnology is now invading the food industry and establishing great potential.Nanotechnology applications in food industry include: encapsulation...
Article
The horse conch, Pleuroploca trapezium is a marine gastropod that is landed in huge amount as by-catch along Gulf of Mannar, southeast coast of India. To make use of this underutilized gastropod meat, ready-to-serve instant soup powder was prepared using this meat with an objective to popularize the meat among local people. This study was intended...
Article
Full-text available
Aim of this work is to significant difference existed in the antioxidant capacity of three different processed purple potato (S. tuberosum L.) extracts assayed via DPPH and FRAPS colorant stability. High temperature treatment would destroy the antho-cyanin compounds and significantly decrease the anthocyanin-based purple potato colorants. Our resul...
Article
This study focuses on the phytochemical properties and the anti-hepatocarcinogenic effects of the leaf and in vitro-derived callus and shoot extracts of Solanum trilobatum. In the leaf, callus and shoot, the presence of sugar, proteins, alkaloids, flavonoids, saponins, tananins, cardiacglycoside, terpenoid and lipids was established by preliminary...
Conference Paper
Full-text available
The development of technology provides a new way in all areas of living. Agriculture is considered as the oldest area which is highly essential for life of earth. Agriculture plays a crucial role in the life of an economy. The importance of agriculture in a country is to provide a Source of Livelihood, Contribution to National Income, Supply of Foo...
Conference Paper
The present study involved the isolation and structural elucidation of the active constituent of gastropod, Drupa margariticola extract using different Chromatographie techniques and various tools of spectral analysis. The acetone phase of the D. margariticola showed promising activity indicating the presence of active fractions. The active compoun...
Conference Paper
Total of 168 marine bacteria was isolated from different marine organisms taken from Pulicat lake, coromandal coast in south india. Antibiotic production by these strains were tested against five test strains, viz., Escherichia coli, Khbsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans. The strain was found to exhib...
Article
The current study was aimed at evaluation of Antioxidant potential of the methanolic extract of Givotia rottlariformis leaves and to elucidate its phytochemical profile using TLC method. The methanol extract of leaves of G. rottlariformis was screened for its antioxidant potential by dot-plot assay, DPPH radical scavenging assay and hydroxyl radica...
Article
Aim of this work is to significant difference existed in the antioxidant capacity of three different processed purple potato (S. tuberosum L.) extracts assayed via DPPH and FRAPS colorant stability. High temperature treatment would destroy the antho-cyanin compounds and significantly decrease the anthocyanin-based purple potato colorants. Our resul...
Article
The ethanolic leaf extracts of Solanum trilobatum plant were used for antibacterial study by disc diffusion method. Different concentrations (10mg/ml, 20mg/ml, 30mg/ml) of the concentrated ethanolic leaf extract were tested for its antibacterial activity against bacterial strains such Bacillusubstilis, Staphylococcus aureus, Bacillus cereus, E. Cal...
Article
The mollusk, Drupamargariticola were collected from the Tuticorin coastal waters of Southeastern India.The crude extract showed promising antibacterial activity against some selected fish pathogens. The crude extract of D. margariticola was purified using chromatography (HPTLC and HPLC) and characterized by spectroscopy (NMR, Mass and IR) technique...
Article
Globally there is steady increase in energy demands. The lack of sustainability of current fossil-centered energy strategies and safety issues relating to nuclear energy has resulted in a shift in energy policies around the world. The need for alternative non-fossil, non-nuclear technology has been stressed by experts and research on this line has...
Article
Globally there is steady increase in energy demands. The lack of sustainability of current fossil-centered energy strategies and safety issues relating to nuclear energy has resulted in a shift in energy policies around the world. The need for alternative non-fossil, non-nuclear technology has been stressed by experts and research on this line has...
Article
Full-text available
A marine epibiotic bacterial strain A4 was isolated from the coral Subergorgia suberosa from Tuticorin coast, Gulf of Mannar region, south east coast of India. Phylogenetic identification based on comparative sequence analysis of 16S rRNA gene indicated that the stain A4 fell under the genera Marinobacterium. The initial screening using agar overla...
Article
Objective: To analyze the antioxidant and antiproliferative potential of Solanum trilobatum was evaluated. Methods: Free radical scavenging potential of the plant was studied by various in vitro assays such as DPPH, ßCarotene and Frap assay. The antiproliferative activity of Solanum trilobatum was analysed by MTT assay. Result: The ethanol extract...
Article
Three species of saltmarsh plants ((Salicornia brachiata, Sesuvium portulacastrum, Suaeda maritima) were screened for herbicidal and growth promoter activities using Lemna Bioassay. Two solvents, hexane and methanol were used for the preparation of crude extracts. Three concentrations (500, 100, and 50 ppm) and a control were tested in duplicates f...
Article
Antioxidants are chemical substances, which can scavenge free radicals and are implicated in the prevention of heart diseases, cancer, ageing etc. Scientists and nutritionist stress the importance of antioxidants and a vast body of literature exit on natural antioxidants from plants. Works relating to the studies on antioxidants in seafoods are lim...
Article
In a screening program, a total of 633 strains were isolated from various marine samples from Tuticorin, southeastern coast of India. In these strains 94 strains were identified as Streptomyces sp. and they were screened for enzyme inhibitors using a general screening method. Angiotensin converting enzyme inhibitors (reduce hypertension either by t...
Data
Full-text available
Objective: To develop a protocol for culturing callus and regenerate shoots invitro from the leaf of Solanum trilobatum and study its anti-hepatocarcinogenic effect in an animal model. Methods: Surface sterilized explants (0.5-1.0 cm) length were placed on the MS basal medium supplemented with various concentrations of 2, for callus induction. MS b...
Article
Food processing industry faces various challenges; one of the foremost challenges is the need for quick and cost effective methods to detect the presence of allergenic components and pathogens in the food. Biosensors pave way for the rapid detection of pathogens, allergens as well as pesticide residues in food. Detection of contaminants, verificati...
Article
The discovery of novel chemical classes has been in decline for the past two decades, the need to exploit new resources in search for effective chemicals with novel mechanism of actions is imperative. Marine bacteria are such a resource yet to be tapped, and the potential it offers is vast. The antitumour assay (artemia toxicity bioassay) developed...
Article
The horse conch, Pleuroploca trapezium is a marine gastropod that is landed in huge amount as by-catch along Gulf of Mannar. Their beautiful shells and operculum are being used for ornamental and medicinal purposes. Even though the meat is not being used locally, small quantities are being exported to Southeast Asian countries like Taiwan. These ba...
Article
Graphene and graphene oxide (GO) layers have become a hotspot so far and have been actively investigated to build new composite materials. These novel nanomaterials have great potential in applications such as electro-chemical devices, energy storage catalysis, and adsorption of enzyme, cell imaging and drug delivery, as well as biosensors. In this...
Article
The function of secondary metabolites in nature is a controversy raging for decades. Interactions between microorganisms are well known phenomena and substrate competition and antagonism are believed to be important in a selection of microflora in a given ecological niche. Although antagonism due to antibiotic production can be easily demonstrated...
Article
Marine microbes use a variety of strategies to colonize both animate as well as inanimate surfaces in marine environment. The competition among microbes to colonize surfaces acts as a potent selective force. One of the important strategies these microbes use is the secretion of antimicrobial compounds, which helps to inhibit the growth of the compe...
Article
____________________________________________________________________________________ The minimum and maximum level of dye degrading bacterial density was found to be 2.1 X 103 CFU/g and 8.5 X 103 CFU/ respectively. The strains were tested for their degradation efficiency using 6 dyes namely Malachite green, Majenta MB, Turquoise blue H, Orange Fast...
Article
Competition amongst microbes for space and nutrients in the marine environment is a powerful selective force which has led to the evolution of a variety of effective strategies for colonizing and growing on surfaces. As the primary role of antimicrobial activity can be to antagonize competitors, bacteria may also produce antimicrobial compounds whe...
Article
Competition amongst microbes for space and nutrients in the marine environment is a powerful selective force which has led to the evolution of a variety of effective strategies for colonizing and growing on surfaces. As the primary role of antimicrobial activity can be to antagonize competitors, bacteria may also produce antimicrobial compounds whe...
Article
Publication Ethics and Publication Malpractice Statement Duties of Editors Confidentiality— Editors of the journal must treat received manuscripts for review as confidential documents. Editors and any editorial staff must not disclose any information about submitted manuscripts to anyone other than the corresponding author, reviewers, other editori...
Article
Full-text available
Aim of this study was to evaluate the antagonistic potential of epibiotic bacteria from seaweeds, Ulva lactuca, Dictyota dichotoma and Padina tetrastromatica against some potent human pathogens. The epibiotic bacteria of Ulva lactuca shows higher level of inhibition properties than the other species. The strain UL1 shows broad spectrum inhibitory a...
Article
The nutritional quality of Pleuroploca trapezium meat was assessed using feeding trails on albino rats. Rats fed with standard casein diet were kept as control. In the test animals, the Protein Efficiency Ratio (PER), assimilation, assimilation efficiency, consumption efficiency and growth efficiency were higher than in the control animals. Protein...
Article
The study was carried out in the field of Aerobiology, Which deals with Microorganism, pollen grains, dust practices and other biological systems in air. This study was conducted to monitor the microbial population present in Neyveli Lignite Corporation Limited (NLC) Environment. The samples were collected on Indoor and outdoor Locations of Neyveli...
Article
Food processing industry faces various challenges; one of the foremost challenges is the need for quick and cost effective methods to detect the presence of allergenic components and pathogens in the food. Biosensors pave way for the rapid detection of pathogens, allergens as well as pesticide residues in food. Detection of contaminants, verificati...
Article
The horse conch, Pleuroploca trapezium is a marine gastropod that is landed in huge amount as by-catch along Gulf of Mannar. Their beautiful shells and operculum are being used for ornamental and medicinal purposes. Even though the meat is not being used locally, small quantities are being exported to Southeast Asian countries like Taiwan. These ba...
Article
An epibiotic bacterial strain designated as P1 with characteristic colony morphology was isolated from five random samplings of the sea fan coral Junceella juncea (Pallas, 1766). Phylogenetic identification based on comparative sequence analysis of 16Ss rRNA gene indicated that the stain P1 fell under the genera Pseudoalteromonas. In the initial sc...
Article
The present study has been focused on to investigate the role of extracts of seaweeds Enteromorpha intestinalis and Sarconema furcellatum against human pathogens. The crude extract of the seaweeds have shown promising activity against most of the screened pathogens. The green algae Enteromorpha intestinalis was very active against human pathogens a...
Article
PEGylation is a modification technique which is widely used in the emerging field of nanomedical imaging and therapy. Nanoparticles are the major components in the nanomedical and it must be protected from the immune system when employed in vivo. This can be achieved by the use of polymer called PEG (Polyethylene Glycol) also known as Carbowax. In...
Article
Crop losses due to pollutant stress are on the rise ever since industrial growth is made. Most of industrial effluents contain lot of toxic substances. When these effluents, without proper treatment are discharged to any land mass or aquatic system cause serious problems to all biological life. Many places in Tamilnadu especially the Tiruppur town...
Article
In sea food industries shellfish waste management is huge problem. It has increasingly difficult and expensive one. This abundant crap and prawn shell waste material has converted to value added products. Chitin was extracted from shell wastes from black tiger shrimp Penaeus monodon and Crap Portunus pelagicus. Shell wastes were collected from sea...
Article
This paper deals with the various ways of using microorganisms as nanomedicines in the medical field. Since long time we were aware of that microorganisms are capable of producing different types of infections and diseases. But these miniature sized organisms can be used as agents in synthesing and also carrying nanomedicines for human therapeutics...
Article
In the present and future, the word innovation refers to the term nanotechnology where everything is possible in this wonder world which scales from 1 to 100 nm which is 1 millionth of a millimeter. Metal Nanoshells are the one such gift by this technology which is a dielectric core material made up of silica covered by thin metals especially gold....
Article
A nanoparticle is a particle having a size range of 1-1000 nm. The main objective of the present work is to prepare the nanoparticles for the sustained delivery of drugs such as Amoxicillin, Ampicillin, Ciprofloxacin and Ofloxacin. These drugs possess less biological half–life which helps in frequent administrations when given in the form of conven...
Article
MEMS plays very important role in building our future techno developments. MEMS finds its footprint in many areas every day. One such area in which it is playing elusive role is the medical field. MEMS has its dendrites in the application of medicine as Bio-MEMS (biological microelectromechanical systems).BioMEMS devices are typically considered as...
Article
Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active substances in the field of the development of bioactive products. In this paper, the molecular diversity of different marine peptides is described a...
Article
Marine organisms fight daily for both food and survival, and this underwater warfare is waged with chemicals. As with plants, researchers have recognized the potential use of this chemical weaponry to kill bacteria or raging cancer cells. Scientists isolated the first marine-derived cancer drug, now known as Cytosar-U, decades ago. Scientists have...
Article
Abstract---- Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environmentand the associated chemical diversity constitute a practicallyunlimited resource of new active substances in the field of thedevelopment of bioactive products. In this paper, the moleculardiversity of different marine peptides is de...
Article
Full-text available
Ganoderma lucidum a medicinal mushroom, which produce polysaccharides that respond to environmental factors directly and for some, the nutritional conditions determine the degree of exopolysaccharide (EPS) formation. In present study the total antioxidant capacity of EPS crude extracts of G. lucidum was found to be maximum in malt medium (82.30 ± 1...
Conference Paper
Full-text available
The present study has been focused on to investigate the role of extracts of seaweeds Enteromorpha intestinalis and Sarconema furcellatum against human pathogens. The crude extract of the seaweeds have shown promising activity against most of the screened pathogens. The green algae Enteromorpha intestinalis was very active against human pathogens a...
Article
In general microorganisms produce secondary metabolites which are not asessential for the survival of the organism. The organism produces an inhibitory product may be an antibiotic which doesn't allow the growth of other organisms. In this present study the bacteria are isolated from the gut of short horned grasshoppers and screened their antagonis...
Article
The aim of this work was to investigate extensively, the biomedical potential of the mollusc Trochus tentorium which are abundantly associated with coral reef of the Tuticorin coastal water. The 100% acetone fraction of the gastropod tested for its analgesic effect on Swiss mice model and anti-inflammatory activity on albino rat showed promising re...
Article
The plants, animals and microorganisms of the marine environment with their wide range of chemical diversity are still an unexplored resource for the development of new agro-chemical agents. Works related to the herbicidal activity of the marine organisms are too scanty. Compared to the search for new pharmaceutical compounds, very little effort ha...
Article
The discovery of novel chemical classes has been in decline for the past two decades, the need to exploit new resources in search for effective chemicals with novel mechanism of actions is imperative. Marine bacteria are such a resource yet to be tapped, and the potential it offers is vast. The antitumour assay (artemia toxicity bioassay) developed...
Article
Herbicides for practical use today are mostly synthetic compounds and they may be classified as follows on the basis of their mode of action, herbicides inhibiting photosynthetic electron transfer, herbicides affecting plant hormonal actions, herbicides interfering with nutritive metabolism, herbicides affecting cell division and microherbicides. S...