Charlotte Amalie Navntoft- PhD
- Senior Scientist at Demant A/S
Charlotte Amalie Navntoft
- PhD
- Senior Scientist at Demant A/S
About
13
Publications
2,523
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68
Citations
Introduction
I am interested in pharmacological approaches and cell- and gene-therapy for hearing loss.
Current institution
Demant A/S
Current position
- Senior Scientist
Additional affiliations
August 2016 - present
May 2016 - present
Position
- PhD Student
Description
- Running title: Neuronal Correlate of Stream Segregation Induced by Rate Cues in a Cochlear-Implanted Mouse Model. Supervisors: Ass Prof Tania Rinaldi Barkat, Basel University; Ass Prof Jeremy Marozeau, Danish Technical University
January 2016 - May 2016
Position
- Research Assistant
Description
- I joined the Barkat Lab to study how the brain detects and perceives sound.
Education
June 2013 - August 2013
Harvard University, Harvard Summer School
Field of study
- Neurobiology, Advanced Systems Biology
February 2013 - June 2015
July 2011 - December 2011
Publications
Publications (13)
Movie of a rotation of a 3D reconstruction a temporal bone specimen injected with steel microspheres.
Movie of a rotation of a 3D reconstruction a temporal bone specimen injected with steel microspheres.
Movie of a rotation of a 3D reconstruction a temporal bone specimen injected with steel microspheres.
Introduction
Cochlear implants (CIs) enhance hearing by stimulating spiral ganglion neurons (SGNs) but are less effective in individuals with compromised SGN functionality. Advances in regenerative medicine suggest that local delivery of medical drugs or cell therapy could regenerate the auditory nerve. This study evaluates a minimally invasive te...
The electric stimulation provided by current cochlear implants (CI) is not power efficient. One underlying problem is the poor efficiency by which information from electric pulses is transformed into auditory nerve responses. A novel stimulation paradigm using ramped pulse shapes has recently been proposed to remedy this inefficiency. The primary m...
In all commercial cochlear implant (CI) devices, the electric stimulation is performed with a rectangular pulse that generally has two phases of opposite polarity. To date, developing new stimulation strategies has relied on the efficacy of this shape. Here, we investigate the potential of a novel stimulation paradigm that uses biophysically-inspir...
Cochlear implants (CIs) are neuroprosthetic devices that can provide a sense of hearing to deaf people. However, a CI cannot restore all aspects of hearing. Improvement of the implant technology is needed if CI users are to perceive music and perform in more natural environments, such as hearing out a voice with competing talkers, reflections, and...
The bradykinesia and other motor signs of Parkinson's disease (PD) are linked to progressive loss of substantia nigra dopamine (DA) neurons innervating the striatum. However, the emergence of idiopathic PD is likely preceded by a prolonged subclinical phase, which may be masked by a variety of pre- and postsynaptic compensatory mechanisms. It is of...
Optogenetics is an emergent technology that combines light-sensitive proteins derived from algae, socalled opsins, with genetics. Viral vectors encoding opsins are injected into selective brain regions whereby specific cell populations can be controlled with high precision light pulses delivered via implanted optical fibres. This review focuses on...
