Charles Ouazana-Vedrines

Charles Ouazana-Vedrines
Université Paris Cité | Paris 5 · Psychiatry

MD PhD Student

About

28
Publications
1,560
Reads
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79
Citations
Education
November 2019 - June 2020
Université Paris Cité
Field of study
  • Cognitive and Behavioral Therapy
October 2019 - October 2020
University of Paris-Sud
Field of study
  • Methodology and Statistics in Biomedical Research
November 2017 - June 2018
Université Paris Cité
Field of study
  • Innovation & Value in Health

Publications

Publications (28)
Article
Objective: The prevalence of depressive and anxiety disorders is higher in women than in men. In contrast, there is still no clear consensus on the existence of sex-related differences in the effectiveness of antidepressant treatments for these disorders. This real-world study used filled prescription sequences to compare antidepressant medications...
Article
Full-text available
Background Should COVID-19 have a direct impact on the risk of depression, it would suggest specific pathways for prevention and treatment. In this retrospective population-based study, we aimed to examine the association of prior SARS-CoV-2 infection with depressive symptoms, distinguishing self-reported v . biologically confirmed COVID-19. Metho...
Article
Objective: The large body of literature examining the association between parenthood and mortality in the general population contrasts with a lack of studies among older adults with schizophrenia. Identifying potential protective factors of premature death in this population is important to help guide prevention measures. Here, we examined whether...
Article
Full-text available
We examined the prospective associations between nicotine dependence and the likelihood of psychiatric and substance use disorders in the general adult population. Participants came from a nationally representative sample of US adults aged 18 years or older, who were interviewed 3 years apart in the National Epidemiologic Survey on Alcohol and Rela...
Article
Introduction This study aimed to analyze factors associated with sick leave in workers affected with persistent symptoms following coronavirus disease 2019 (COVID-19). Methods Workers attended a multidisciplinary day-hospital program with a comprehensive assessment for persistent symptoms after COVID-19 that included medical evaluation and standar...
Article
Full-text available
Background Identifying factors that predict the course of persistent symptoms that occurred during the COVID-19 pandemic is a public health issue. Modifiable factors could be targeted in therapeutic interventions. Objective This prospective study based on the population-based CONSTANCES cohort examined whether the psychological burden associated w...
Preprint
Full-text available
Women are unexplainedly more affected than men by post-COVID-19 persistent symptoms. Depressive symptoms may partially explain these gender differences. In the French population-based CONSTANCES cohort, depressive symptoms were measured with the 9-item Patient Health Questionnaire (PHQ-9) between April 6 and May 4, 2020. Between December 2020 and J...
Article
Full-text available
Prior evidence indicates the potential central role of the acid sphingomyelinase (ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a multicenter retrospective observational study including 72,105 adult patients with laboratory-confirmed SARS-CoV-2 infection who were admitted to 36 AP-HP (Assistance Publique–Hôpitaux de P...
Article
Full-text available
Many patients affected by COVID-19 suffer from debilitating persistent symptoms whose risk factors remained poorly understood. This prospective study examined the association of depression and anxiety symptoms measured before and at the beginning of the COVID-19 pandemic with the incidence of persistent symptoms. Among 25,114 participants [mean (SD...
Article
Background: Material conditions of lockdown and changes in regular functioning may have played a role on depressive manifestations. We aimed to examine the association between housing conditions and changes in professional activity and depression during the first COVID-19 outbreak in France. Method: Participants of the CONSTANCES cohort were fol...
Article
Objective: To examine the association between trust in different sources of information on COVID-19 at the beginning of the pandemic and the burden of incident persistent symptoms. Methods: This prospective study used data from the SAPRIS and SAPRIS-Sérologie surveys nested in the French CONSTANCES population-based cohort. Trust in different inf...
Article
Ranking antidepressants according to their acceptability (i.e., a combination of both efficacy and tolerability) in the general population may help choosing the best first-line medication. This study aimed to replicate the results of a proof-of-concept study ranking anti-depressants according to the proportion of filled prescription sequences consi...
Article
Background: Although about half of patients do not respond to a first-line antidepressant medication, there is no consensus on the best second-line option. The aim of this nationwide population-based study was to rank antidepressants according to their relative acceptability (ie, efficacy and tolerability) using filled prescription sequences after...
Article
Full-text available
Background Naturalistic studies regarding clinical outcomes associated with antidepressant treatment duration have yielded conflicting results, possibly because they did not consider the occurrence of treatment changes. This nation-wide population-based study examined the association between the number of filled prescriptions and treatment changes...
Article
Introduction A l’ère de la prophylaxie anti-cytomégalovirus (CMV) systématique post transplantation (Tx), l’impact du statut sérologique CMV du donneur et receveur sur la mortalité est débattu. L’objectif était d’étudier la mortalité et la morbidité à 5 ans post-Tx chez des transplantés pulmonaires séronégatifs pour le CMV (R-) selon le statut séro...
Article
Full-text available
On 11 March 2020, the WHO declared COVID-19 as a Public Health Emergency of International Concern. In Europe, particularly in France, hospitals were urged to take prompt measures: cancellation of non-emergent procedures, dedication of units and wards to patients with COVID, and reallocations of medical and non-medical staff. On 16 March 2020, three...
Book
Full-text available
VBHC provides a methodology for measurable health and care outcomes that make the biggest difference to patients, while driving cost efficiencies within health services. The EIT Health handbook and framework explores insights from pioneers in the field and defines the key steps critical to implementing VBHC in health services. Directed by Professo...

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