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Charilaos Papafragkakis

Charilaos Papafragkakis
Private Practice

M.D.

About

54
Publications
5,574
Reads
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340
Citations
Citations since 2016
18 Research Items
268 Citations
2016201720182019202020212022010203040
2016201720182019202020212022010203040
2016201720182019202020212022010203040
2016201720182019202020212022010203040
Additional affiliations
July 2015 - June 2016
University of Texas MD Anderson Cancer Center
Position
  • Therapeutic Endoscopy Fellow

Publications

Publications (54)
Article
Full-text available
Background: Gastric diverticula (GD) are outpouchings of the stomach wall that typically form in the fundus. They are the least common gastrointestinal diverticula, and are very rare anatomic abnormalities overall. Summary: Although most GD are asymptomatic and are usually discovered incidentally during routine diagnostic testing, they can prese...
Chapter
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and biopsy (FNB) has been widely accepted as a fundamental procedure for the diagnosis and staging of lesions of the gastrointestinal tract or non-gastrointestinal lesions within reach of the aspiration needle. EUS-FNA has been used in lesions of the esophagus, mediastinal lesions, lymph...
Article
Full-text available
Background and aims: Pancreas cancer (PC) is a deadly disease, which is most commonly diagnosed at an incurable stage. Different high-risk genetic variants and cancer syndromes increase the lifetime risk of developing PC. This study aims to assess the yield of initial PC screening in patients with high-risk germline mutations. Methods: Asymptoma...
Article
Full-text available
Small intestinal tumors are rare with adenocarcinoma of the small intestine accounting for less than 2% of all gastrointestinal cancers. Primary jejunal adenocarcinoma constitutes a minute portion of small intestine adenocarcinomas. Clinically, this cancer presents at latter stages of its progression, mainly due to vague and non-specific symptoms,...
Article
Full-text available
Henoch-Schonlein purpura (HSP) is an immune-mediated vasculitis. HSP presents with purple spots on the skin (purpura), arthralgia, digestive problems, and kidney injury. HSP is most commonly seen in children, and rarely presents in adults. The pathogenesis involves the deposition of immune complexes in small to medium size blood vessels which leads...
Article
Full-text available
Cholangioarcinoma is a rare but dreadful malignancy which poses much difficulties in the management. If detected early with only localized disease, curative resection is possible. However, most patients present in the late stages of the disease, which are managed with endoscopic biliary drainage and/or chemoradiation. Liver transplantation offers a...
Article
Full-text available
Cholangiocarcinoma is the second most common primary hepatic malignancy and its incidence is increasing worldwide. Classification and staging of intrahepatic, perihilar, and distal cholangiocarcinomas provide useful prognostic information and further guide in their management. Establishing diagnosis is frequently challenging and may require a multi...
Article
Background and aims: Current modalities for lymph node staging in cancer can be limited. We sought to evaluate the feasibility of needle-based confocal laser endomicroscopy (nCLE) at the time of endoscopic ultrasound (EUS) and to describe the nCLE features that distinguish between benign, malignant, and inflammatory lymph nodes. Methods: We coll...
Article
Full-text available
Many herbal preparations are routinely used and have been occasionally associated with a wide range of side effects, from mild to severe. Chinese skullcap and black catechu are herbal medications commonly used for their hepatoprotective and other properties. We report a case of acute toxic hepatitis associated with ingestion of Chinese skullcap and...
Article
Full-text available
The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated amin...
Article
Full-text available
Link to PDF: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460383/pdf/AnnGastroenterol-28-406.pdf Colonoscopic diagnosis of cecal worms (Trichuris trichiura) Mel A. Ona, Haris Papafragkakis, Madhavi Reddy The Brooklyn Hospital Center, NY, USA Two unrelated Bangladeshi women, a 61-year-old with chronic diarrhea, lower abdominal pain, poor appetit...
Article
Full-text available
Gastrointestinal bleeding is a leading cause of morbidity and mortality in the United States. The management of gastrointestinal bleeding is often challenging, depending on its location and severity. To date, widely accepted hemostatic treatment options include injection of epinephrine and tissue adhesives such as cyanoacrylate, ablative therapy wi...
Article
Full-text available
Background: The prevalence of hepatitis C in the United States is estimated to be 1-1.5% (2.7 to 3.9 million persons). Birth-cohort screening with linkage to care is recommended to augment risk-based screening programs in reducing hepatitis C-associated morbidity and mortality. However, only a small percentage of hepatitis C patients are identified...
Article
Full-text available
The use of hyaluronic acid and dextranomer (Solesta, Salix) injection in the anal canal is an emerging modality in the treatment of fecal incontinence. However, little is known regarding the endoscopic and radiological appearance following injection of this ano-rectal bulking agent. We report computed tomography and endoscopic findings after hyalur...
Article
Full-text available
Sickle cell intrahepatic cholestasis is a relatively uncommon complication of homozygous sickle cell anemia, which may lead to acute hepatic failure and death. Treatment is mainly supportive, but exchange transfusion is used as salvage therapy in life threatening situations. We describe a case of a 16-year-old female with homozygous sickle cell ane...
Article
Full-text available
Bariatric surgery aims at weight reduction of severely obese patients. The Roux-en-Y technique is one of the most common bariatric procedures and is occasionally accompanied by nutrient insufficiencies and metabolic changes. According to the literature, skin architecture and immunity change after bariatric surgery and may lead to inflammation and i...
Article
Acute fatty liver of pregnancy is a rare but serious and potentially fatal complication of pregnancy. It typically presents in the third trimester with microvesicular fatty infiltration of the liver and can lead to multiorgan failure and death. Differentiation from hemolysis-elevated liver enzymes-low platelets syndrome can guide management. A high...
Article
Background: Advances in endoscopic and surgical techniques have increased the frequency and complexity of these procedures, and thus, the incidence of associated complications. Aims: To describe the use and clinical applications of the Over the Scope Clip (OTSC) system. Methods: An English language literature search was conducted using the key...
Article
Full-text available
Interferon remains an essential component of treatment regimens for chronic hepatitis C infection. Mood disturbances, including depression, are relatively common in the hepatitis C virus-infected population and may worsen during hepatitis C treatment. Screening for depression prior to commencement of therapy is crucial and may improve treatment out...
Article
Chronic viral hepatitis remains common in the hemodialysis (HD) and renal transplantation population although measures to limit spread of hepatitis infection in HD units have markedly reduced its prevalence. Our review focuses on the current management of hepatitis B and C infections in renal transplant candidates before and after renal transplanta...
Article
Full-text available
Hemangiomas are the most common benign tumors found in the liver, typically asymptomatic, solitary, and incidentally discovered. Although vascular in nature, they rarely bleed. We report a case of a 52-year-old woman with a previously stable hemangioma who presented to our hospital with signs and symptoms indicative of spontaneous rupture. We revie...
Article
Since the implementation of the model for end-stage liver disease scoring system for organ allocation in orthotopic liver transplantation in 2002, the number of combined liver and kidney transplantations (CLKTs) that have been performed in the USA has increased significantly. To standardize the evaluation and selection of CLKT candidates, consensus...

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