Chao-Min Wang- DVM; Ph.D
- Professor (Assistant) at National Chiayi University
Chao-Min Wang
- DVM; Ph.D
- Professor (Assistant) at National Chiayi University
Professor (Assistant).
Department of Veterinary Medicine,
National Chiayi University.
About
100
Publications
8,532
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971
Citations
Introduction
Veterinary Microbiology, Microbial Ecology, Allelopathy, Natural product with biomedical influence.
Current institution
Additional affiliations
August 2020 - present
August 2020 - December 2020
July 2016 - July 2020
Education
September 2001 - June 2008
Publications
Publications (100)
The aims of this study were to identify and characterize the novel thermophilic, cellulose-degrading bacterium Paenibacillus sp. strain B39.
Strain B39 was closely related to Paenibacillus cookii in 16S rRNA gene sequence. Nonetheless, this isolate can be identified as a novel Paenibacillus sp. with respect to its physiological characteristics, bio...
The number of people who raise reptiles as pets has increased, but information about zoonotic Campylobacter carried by reptiles is limited. A survey of zoonotic Campylobacter species isolated from reptiles was undertaken to understand the possibility of this zoonotic bacterial pathogen causing human infection. A total of 179 fresh reptile fecal sam...
Rhododendron formosanum is distributed widely in the central mountains in Taiwan and the major allelopathic compound in the leaves has been identified as (-)-catechin, which is also a major allelochemical of an invasive spotted knapweed in North America. Soil microorganisms play key roles in ecosystems and influence various important processes, inc...
(1) Background: Several triterpenoids were found to act synergistically with classes of antibiotic, indicating that plant-derived chemicals have potential to be used as therapeutics to enhance the activity of antibiotics against multidrug-resistant pathogens. However, the mode of action of triterpenoids against bacterial pathogens remains unclear....
Alstonia scholaris is a tropical evergreen tree native to South and Southeast Asia. Alstonia forests frequently lack understory species. However, potential mechanisms-particularly the allelochemicals involved-remain unclear. In the present study, we identified allelochemicals of A. scholaris, and clarified the role of allelopathic substances from A...
Background
Pasteurella multocida causes progressive atrophic rhinitis and suppurative bronchopneumonia in pigs, which results in severe economic losses in swine industry. This study aimed to determine the serovar, genotype and prevalence of toxA virulence gene of Pasteurella multocida isolates collected in Taiwan. A total of 164 Pasteurella multoci...
Background
Glaesserella parasuis ( G. parasuis ) belongs to the normal microbiota of the upper respiratory tract in the swine, but virulent strains can cause systemic infections commonly known as Glässer’s disease that leads to significant economic loss in the swine industry. Fifteen serotypes of G. parasuis have been classified by gel immunodiffus...
Toltrazuril (TZR) is currently the only registered chemotherapeutic drug in the European Union for the treatment of Cystoisospora suis. This study investigated the comparative pharmacokinetics and tissue concentration-time profiles of TZR and its active metabolite, toltrazuril sulfone (TZR-SO2 ), after oral (per os, p.o.) and intramuscular (i.m.) a...
Streptococcus suis (S. suis) infection can cause clinically severe meningitis, arthritis, pneumonia and septicemia in pigs. To date, studies on the serotypes, genotypes and antimicrobial susceptibility of S. suis in affected pigs in Taiwan are rare. In this study, we comprehensively characterized 388 S. suis isolates from 355 diseased pigs in Taiwa...
The zoonotic bacteria Capnocytophaga canimorsus and C. cynodegmi, the predominant Capnocytophaga species in the canine oral biota, can cause human local wound infections or lethal sepsis, usually transmitted through dog bites. Molecular surveying of these Capnocytophaga species using conventional 16S rRNA-based PCR is not always accurate due to the...
Molish in 1937 coined Allelopathy from two Greek words, 'allelo' (means two organisms) and 'pathy' (means harm). The term defined as plant released metabolites into environment through ecological processes: volatilization, leaching, root exudation and decomposition of plant debris in soil, resulting in detrimental effects on understorey or neighbou...
We investigated the antimicrobial activity and membrane disruption modes of the antimicrobial peptide mastoparan-AF against hemolytic Escherichia coli O157:H7. Based on the physicochemical properties, mastoparan-AF may potentially adopt a 3–11 amphipathic helix-type structure, with five to seven nonpolar or hydrophobic amino acid residues forming t...
This essay aimed to describe the allelopathy researches in the past, present and future, dealing with the allelopathy in natural and managed ecosystems. The unique allelopathic patterns of chaparral, coniferous forests, fern vegetations, tropical and subtropical vegetations from forests to grassland communities and introduced and invasive species a...
The microbial communities on the skin of dogs include several species of bacteria, which contrib-ute to skin health and disease. Staphylococcus pseudintermedius, cultured at high frequency from the skin of dogs, is an opportunistic pathogen causing superficial pyoderma. Effective treatment against S. pseudintermedius infections is an important issu...
In Taiwan, freshwater clams (Corbicula fluminea) and hard clams (Meretrix lusoria) are the most frequently raised shellfish in land-based pond aquaculture, but research on the accumulation of organochlorine pesticides (OCPs) in these shellfish is limited. We detected the levels of 14 OCPs in 62 shellfish from Taiwanese aquafarms by performing gas c...
Vaccinium emarginatum Hayata is a medicinal plant that has been historically used in ethnopharmacy to treat diseases in Taiwan. The objective of this study is to evaluate the anti-cancer and anti-bacterial constitutes from the root nodule extract of V. emarginatum. The chemical composition of V. emarginatum fractions was analyzed by high-performanc...
一種控制及預防青枯病之組合物，包含生長素與細胞分裂素。並提供一種使用該組合物以控制及預防青枯病之方法。
A composition for controlling and preventing bacterial wilt
includes auxin and cytokinin . A method for controlling and
preventing bacterial wilt by using the composition is also
Mar. 24 , 2020 ( TW ) 109109862 provided .
Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects. However, the mechanisms of imipramine-associated disruption to metabolism and negative hepatic, renal, and retinal effects are not well defined. In this study, we evaluated C57BL6/J m...
Clozapine is widely employed in the treatment of schizophrenia. Compared with that of atypical first-generation antipsychotics, atypical second-generation antipsychotics such as clozapine have less severe side effects and may positively affect obesity and blood glucose level. However, no systematic study of clozapine’s adverse metabolic effects—suc...
Zotarolimus is a semi-synthetic derivative of rapamycin and a novel immunosuppressive agent used to prevent graft rejection. The pharmacological pathway of zotarolimus restricts the kinase activity of the mammalian target of rapamycin (mTOR), which potentially leads to reductions in cell division, cell growth, cell proliferation, and inflammation....
Liver disorders have been recognized as one major health concern. Fucoidan, a sulfated polysaccharide extracted from the brown seaweed Fucus serratus, has previously been reported as an anti-inflammatory and antioxidant. However, the discovery and validation of its hepatoprotective properties and elucidation of its mechanisms of action are still un...
Doxepin is commonly prescribed for depression and anxiety treatment. Doxepin-related disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the underlying mechanism of action warrants further research. Here, we investigated how doxepin affects lipid change, glucose homeostasis, chromium (Cr) distribution, renal impairment...
Everolimus, which inhibits mTOR kinase activity and is clinically used in graft rejection treatment, may have a two‐sided influence on metabolic syndrome; its role in obesity and hyperglycemic in animals and humans, however, has been explored insufficiently. This study further determined how continual everolimus treatment affects glucose homeostasi...
Essential oils from the dried spikes of Nepeta tenuifolia (Benth) are obtained by steam distillation. Pulegone was identified as the main component in the spikes of N. tenuifolia through analysis, with greater than 85% purity obtained in this study. The essential oils are extremely active against all Gram-positive and some Gram-negative reference b...
Eudesmin has been proven to possess anti-inflammatory effects. In the present study, the effects of eudesmin on Helicobacter pylori (H. pylori)-mediated autophagy, apoptosis, immune response and inflammation were determined in human gastric adenocarcinoma (AGS) cells in vitro and in C57BL/6 mice in vivo. Detection of the production of interleukin (...
(1) Background: In China and South Asia, Alstonia scholaris (Apocynaceae) is an important medicinal plant that has been historically used in traditional ethnopharmacy to treat infectious diseases. Although various pharmacological activities have been reported, the anti-lung cancer components of A. scholaris have not yet been identified. The objecti...
(1) Background: Alstonia scholaris (Apocynaceae) is an important medicinal plant that has been historically used in “Dai” ethnopharmacy to treat infectious diseases in China. Although various pharmacological activities have been reported, the antimicrobial constitutes of A. scholaris have not yet been identified. The objective of this study is to e...
In our previous study, ursolic acid present in leaves of Rhododendron formosanum was found to possess anti-neoplastic activity. We further isolated and unveiled a natural product, cinnamtannin D1 (CNT D1), an A-type procyanidin trimer in R. formosanum also exhibited anticancer efficacy that induced G1 arrest (83.26 ± 3.11% for 175 M CNT D1 vs 69.2...
Rhododendron formosanum is an endemic species distributed in the central mountains of Taiwan. In this study, the biological activities of major procyanidins isolated from the leaf extract of R. formosanum were investigated. Four compounds, including two procyanidin dimers, procyanidin A1 (1) and B3 (2), and two procyanidin trimmers, procyanidin C4...
Numerous epidemiological studies have associated elevated serum phosphorus levels with cardiovascular disease and the risk of death in the general population as well as in chronic kidney disease (CKD) and dialysis patients. In this study, we explored whether elevated phosphate conditions induce cardiac hypertrophy and attempted to identify the mole...
Seven new δ-tocotrienols, designated litchtocotrienols A-G (1-7), together with one glorious macrocyclic analogue, macrolitchtocotrienol A (8), and one new meroditerpene chromane, cyclolitchtocotrienol A (9), were isolated from the leaves of Litchi chinensis. Their structures were mainly determined by extensive spectroscopic analysis and their biol...
The whole-genome sequence for Campylobacter fetus subsp. testudinum, a pathogen isolated from humans and turtles, has been reported recently. We present another completed genome sequence of
the C. fetus subsp. testudinum strain pet-3, which was isolated from a lizard in Taiwan, for further genomic comparison study.
The aim of the present study was to investigate whether Rhododendron formosanum Hemsl. (Ericaceae), an endemic species in Taiwan, exhibits antineoplastic potential against non-small-cell lung carcinoma (NSCLC). R. formosanum was successively extracted with methanol and then separated into dichloromethane (RFL-DCM), ethyl acetate (RFL-EA), n-butanol...
Nine new derivatives of oleanane triterpenoids isolated from Fatsia polycarpa Hayata were synthesized through chemical transformations. Acetylation was effected by reaction with acetic anhydride in pyridine to afford compounds 1–5, while compound 6 was obtained using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC·HCl) in CH2Cl2. T...
This study aimed to exploit the allelopathic potential of Litchi chinensis (Litchi) and its application as naturally occurring herbicide in the field. Aqueous leaf extracts of L. chinensis inhibited the radicle growth of test weeds. Allelopathic compounds presented in litchi leaves were identified as (-)-epicatechin, procyanidin A2, kaempferol-3-O-...
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using Pintail 1.0. ##Assembly-Data-START## Assembly Method :: BioEdit v. 7.1.3.0 Coverage :: 40% Sequencing Technology :: ABI 3730 ##Assembly-Data-END##
Seven new oleanane-type triterpenoids (1-7), named fatsicarpains A-G, and the known compounds 3α-hydroxyolean-11,13(18)-dien-28-oic acid (8) and 3α-hydroxyolean-11-en-28,13β-olide (9) were isolated from the leaves and twigs of Fatsia polycarpa on the basis of bioassay-guided fractionation. The structures of compounds 1-7 were elucidated through spe...
本发明公开了一种利用含植物纤维的原料生产饲料的方法。该方法，是将地衣芽孢杆菌(Bacillus licheniformis)BL57 CGMCC No.2277和/或地衣芽孢杆菌(Bacilluslicheniformis)BL54 CGMCCNo.2276接种到含植物纤维的原料中，在30-50℃发酵，干燥得到饲料。本发明，利用植物秸秆等农业废弃物以及工业发酵废弃物(如酒糟)进行发酵，制成饲料，充分利用了废弃物，可以将废弃物中的纤维素大量转换成还原糖(转换后还原糖最高可达玉米粉之90％)，不仅大大增加了废弃物的利用价值，而且制成的饲料具有利于消化、营养全面等功效。
本发明公开了一株地衣芽孢杆菌及其应用。该地衣芽孢杆菌为地衣芽孢杆菌(Bacillus licheniformis)BL54 CGMCC №.2276。本发明的地衣芽孢杆菌(Bacilluslicheniformis)BL54可利用含纤维素的工农业废弃物为原料，如植物秸秆、叶片、其它农业废弃组织、酒糟等，将这些原料其中的纤维素转化为还原糖，大大提高了废弃物的利用价值。
本发明公开了一株地衣芽孢杆菌及其应用。该地衣芽孢杆菌为地衣芽孢杆菌(Bacillus licheniformis)BL57CGMCC №.2277。本发明的地衣芽孢杆菌(Bacilluslicheniformis)BL57可利用含纤维素的工农业废弃物为原料，如植物秸秆、叶片、其它农业废弃组织、酒糟等，将这些原料其中的纤维素转化为还原糖，大大提高了废弃物的利用价值。
ABSTRACTA novel Bacillus species of Calculus Bovis (cow gallstone) was isolated and identified in this study. Morphological features, bacterial fatty acid analysis using a microbial identification system, carbon source utilization profiles using Biolog system and 16S rDNA sequencing were employed to identify the isolated bacterium. This isolated ba...
This study investigated the species diversity and substrate utilization patterns of culturable thermophilic bacterial communities in hot aerobic poultry and cattle manure composts by coupling 16S rDNA analysis with Biolog data. Based on the phylogenetic relationships of 16S rDNA sequences, 34 thermophilic (grown at 60 degrees C) bacteria isolated d...
On Aug 20, 2007 this sequence version replaced gi:76162842.
本研究主要目的是瞭解台灣地區禽畜糞好氣式堆肥處理過程中，在不同溫度條件下之細菌相，並分離及鑑定嗜高溫菌種以供將來進一步篩選為堆肥處理菌種。我們自不同堆肥場採樣，以隨機挑取菌落方式分離菌株後，經 Biolog MicroStation系統進行菌種分類鑑定。結果顯示30℃菌相以葡萄球菌屬(Staphylococcus spp.)、棒狀桿菌屬(Corynebacterium spp.)、不動桿菌屬(Acinetobacter spp.)、CDC group E 為主；40℃菌相以Corynebacterium spp.、CDC group、芽胞桿菌屬(Bacillus spp.)、Acinetobacter spp.為主；50℃菌相以Bacillus spp.、耳炎蘇黎世菌(Turicella o...
本研究分析16S rDNA序列及Biolog生化資料，探討在禽糞及牛糞堆肥之嗜高溫菌的菌相及其利用之物質。此外，在研究過程中發現一個會分解纖維素（cellulose）的嗜高溫Paenibacillus新菌株。根據16S rDNA序列分析建構親緣演化關係，本研究自好氣式堆肥分離之34株嗜高溫菌（培養於60°C）分別鑑定為Bacillus licheniformis、B. atrophaeus、Geobacillus stearothermophilus、G. thermodenitrificans、Brevibacillus thermoruber、Ureibacillus terrenus、U. thermosphaericus及Paenibacillus cookii。其中，B. atro...
