Chao Guo

Peking University | PKU

Taste preference is a pivotal predictor of nutrient intake, yet its impact on mild cognitive impairment (MCI) remains poorly understood. We aimed to investigate the association between taste preferences and MCI and the role of cardiometabolic diseases (CMDs) in this association. The study included older adults, aged 65-90, with normal cognitive fun...

Population aging is an irreversible process in the development of modern society, which brings challenges to comprehensive modernized social governance. Population aging is a "dualistic" development issue that not only leads to aging of the labor force structure but also creates new demographic dividends. This study describes the core thoughts of d...

Background Despite accumulating evidence of the long-term impacts of childhood sexual abuse (CSA), few studies have investigated the association between CSA and early sexual debut among adolescents. In this study, we examine the relationship between CSA and early initiation of sexual intercourse among Chinese youth, and the role of school-based sex...

BACKGROUND Doctors have become the focus of social attention, and trust in doctors is related to everyone's health. OBJECTIVE This study examined the association between Internet use behaviors, network information literacy, and trust in doctors. And to analyze the age heterogeneity of the relationship mentioned above and test the mediation role of...

Background In China, numerous people still rely on solid fuel for household use. To date, the association between household solid fuel use and functional disability, and what benefit reducing household solid fuel usage could bring at the population level to China remain unclear. Method Data were from the China Health and Retirement Longitudinal St...

Background At a time when a highly contagious pandemic and global political and economic turmoil are intertwined, worldwide cooperation under the leadership of an international organization has become increasingly important. This study aimed to estimate the effect of COVID-19 on public confidence in the World Health Organization (WHO), which will s...

Synopsis More efforts should be made to support pregnant women to prevent the long‐term effects of prenatal exposure to disasters on the health of their offspring.

This research accordingly examines the effect of childhood social relationships on the use of mobile payment and e-money among Chinese middle-aged and older adults from a life course perspective and tests the mediation role of social activities in such a path with the Karlson–Holm–Breen (KHB) method. The findings support that good childhood communi...

Background In China, numerous people still rely on solid fuel for household use. To date, the association between household solid fuel use and functional disability, and what benefit reducing household solid fuel usage could bring at the population level to China remain unclear. Method Data were from the China Health and Retirement Longitudinal Stu...

Objectives : This study aimed to investigate the associations between individual-level SES, area-level SES, and their interaction with dementia in China. Methods : This study used data from the Second China National Sample Survey on Disability and restricted our finalized analysis to 688507 participants aged 50 years or older. Dementia was ascerta...

Objectives To estimate the association between the 2008 Beijing Olympic Games (BOG) and growth of children in China. Methods A total sample of 6 951 children aged 3–10 years were included, among which 3 201 were interviewed in 2014 and 3 750 were interviewed in 2018. The BOG was used as a natural experiment. Exposure to the BOG was established by...

What is already known on this topic?: Diverse social factors such as economic development, policy, culture, and special historical events could affect population fertility directly. At present, the influence of social factors on fertility is still controversial. With the diversification of population characteristics, the cross-group robustness of...

Objective: To design demand-oriented intelligent analysis platform framework for the disabled population data from overall management to security. Methods: DATAI-WebEx, active learning, Browser/Server architecture, role-role-based access control, Bayesian network, GIS analysis technology, cluster analysis, regression analysis and other intellige...

What is already known about this topic? A previous study found that the size of population with disability was 52.7 million and 84.6 million in 1987 and 2006, with the weighted disability rate of 4.9% and 6.5%, respectively. What is added by this report? This study restored the prevalence of disability and its change trajectory in China during 1...

Objective Schizophrenia is a public concern in metropolises. Increases in city size may strengthen the correlation between prevalence of schizophrenia and indices of socioeconomic status, such as education. This study used population-based data of adults to investigate the association between education and schizophrenia in Chinese metropolises and...

The aim of the study was to profoundly gain understanding into specific cultural values that underlie traditional practices which pose as barriers to rural girls' education in Zambia. A pairwise case study approach was used to identify and describe types of cultural values prevalent in the Bemba and Tonga ethnic groups of Zambia. A total of 28 inte...

Background More research is needed to understand the long-term effects of prenatal exposure to adverse events, such as floods and other natural disasters, on cognitive outcomes in childhood. We aimed to explore the risk of cognitive impairment in children following maternal exposure to the 1998 Yangtze River flood in China during pregnancy. Method...

Objective: Although higher prevalence of schizophrenia in Chinese urban areas was observed, studies focused on the association between schizophrenia and urbanicity were less in China. Using a national representative population-based data set, this study aimed to investigate the relationship between urbanicity and schizophrenia and its related mort...

Background We aimed to explore HIV RNA (ribonucleic acid) virologic levels greater than 1,000 copies/millilitre (ml), among HIV-positive adolescents aged 15–24 years, establish the spread of CD4 T- cell counts and inspect characteristics of adolescents presenting with new HIV infections, including co-infections with Hepatitis B virus and syphilis....

What is already known about this topic? Along with the quick change of society and health transformation, as well as the continued expansion of urbanization, the health risk and its variation of migrants in China would became more complicated. What is added by this report? Although a decreasing net migration flow trend was presented from 2015 to...

What is already known about this topic? In the context of rapid population ageing and over represented disabilities among the elderly, healthcare services for the elderly persons with disabilities are one of the most urgent and important population and public health issues. Previous studies indicated that the weighted prevalence rate of lifetime h...

Objectives: This study investigated the relationship between urbanicity and dementia, and predicted its non-linear pattern among Chinese adults aged 50 years old and above. Methods: This study used data from the Second National Sample Survey on Disability, which was implemented from 1 April to 31 May 2006 across China. Dementia status was determ...

Background: Improving education level was evidenced to decrease the risk of schizophrenia, but whether this strength of education role depends on gender is not. This study aimed to investigate whether there was gender difference in the association between education and schizophrenia in Chinese adults. Methods: Data were obtained from the Second...

Most childhood disabilities are caused by congenital factors such as birth defects. The present study aims to evaluate the effect of periconceptional nutrition intervention on the prevention of congenital disability among Chinese children using the National Birth Defects Intervention Project as a natural experiment. We obtained individual-level dat...

Objective: Improving education level was evidenced to decrease the risk of schizophrenia, but whether this strength of education role depends on gender is not. This study aimed to investigate whether there is sex difference in the association between education and schizophrenia in Chinese adults. Methods: Data was obtained from the Second China Nat...

Objectives: Increased risk of autism with the increment of urbanization has been documented in developed countries. However, very few studies in developing countries focused on this topic. By using Chinese nationally representative large dataset, we investigated the association between urbanicity and autism among children aged 0-17 years in China....

Objective: Improving education level was evidenced to decrease the risk of schizophrenia, but whether this strength of education role depends on gender is not. This study aimed to investigate whether there is sex difference in the association between education and schizophrenia in Chinese adults. Methods: Data was obtained from the Second China Nat...

Background: Improving education level was evidenced to decrease the risk of schizophrenia, but whether this strength of education role depends on gender is not. This study aimed to investigate whether there was gender difference in the association between education and schizophrenia in Chinese adults. Methods: Data were obtained from the Second Chi...

Objectives Health disparities in schizophrenia are well established. However, it is less understood whether area-level socioeconomic status (SES) is differentially associated with schizophrenia depending on individual-level SES. Therefore, using a nationally large representative data, this study investigated the association between individual-level...

Introduction Early pregnancies and their poor reproductive outcomes remain increasing concerns. Aim This study aims to investigate the pregnancy rate and outcomes and to identify social factors associated with pregnancy among Chinese unmarried youths aged 15–24 years. Methods Data were obtained from the Survey of Youth Access to Reproductive Heal...

Background Maternal exposure to major stressors during pregnancy has been found to increase the risk of neurodevelopmental, cognitive and psychiatric disorders in the offspring. However, the association between prenatal exposure to earthquake and the risk of adult schizophrenia has yet to be examined. Aims To explore the potential long-term effect...

Background: Youth with disability contribute to a high burden of disease but are often neglected. This study aims to estimate the prevalence of disability and its association with poverty among Chinese youth aged 15-24 years. Methods: Data were obtained from a nationally representative population-based cross-sectional survey in 2006 and its foll...

Background Early pregnancy among unmarried youth is a serious public health challenge. Male youth’s knowledge, attitude and practice (KAP) of sexual and reproductive health (SRH) and its association with the risk of their sexual partners’ pregnancy in China remains unexplored. This study investigates the KAP among Chinese unmarried male youth aged...

Showed the details of knowledge, attitude and practice questions of sexual reproductive health in the questionnaire from Survey of Youth Access to Reproductive Health in China (YARHC). (DOCX)

Purpose This study aimed to examine the long-term effect of prenatal exposure to the Sino-Japanese War during 1937–1945 on risk of schizophrenia in adulthood among Chinese wartime survivors. Methods We obtained data from the Second National Sample Survey on Disability conducted in 31 provinces in 2006. We restricted our analysis to 369,469 adults...

Little is known about the male experience of premarital pregnancy (MEPP) and the sociodemographic characteristics of unmarried male youths involved in pregnancy. This study estimates the prevalence of MEPP and identifies the sociodemographic factors associated with it among Chinese unmarried youths aged 15-24 years, using data from the Survey of Yo...

Introduction Adolescents are at high risk for negative health outcomes associated with high-risk sexual behaviors (HRSBs), and researchers have attempted to identify factors that influence such behavior so that meaningful prevention and intervention programs may be developed. Aim To investigate the associations between CSA experience and HRSBs in...

Background: Young women are disadvantaged with respect to their ability to access contraception, which puts them at especially high risk of repeat induced abortion. This study aims to estimate the prevalence of repeat induced abortion and to identify its association with risky sexual behaviors among unmarried young women in China. Materials and m...

There is little evidence on the association between area-level social factors and schizophrenia in China. This study aimed to investigate the relationship between county-level social factors and schizophrenia in Chinese adults aged 18 years old and above. We obtained data from the Second China National Sample Survey on Disability, and selected 1,90...

The current measures of cognitive functioning in adulthood do not indicate a long-term association with prenatal exposure to the Dutch famine. However, whether such association emerges in China is poorly understood. We aimed to investigate the potential effect of prenatal exposure to the 1959–1961 Chinese famine on adult cognitive impairment. We ob...

This study aimed to investigate the prevalence rate and associated factors of co-morbid mental disability among the elderly with motor disability. Data was obtained from the second China National Sample Survey on Disability (CNSSD). 250,752 older adults aged 65 years and above were sampled from 5964 sites, 2980 towns, 734 counties in 31 provinces i...

Background: Schizophrenia is a common major mental disorder and prenatal nutritional deficiency may increase its risk. We aimed to investigate long-term impact of prenatal exposure to malnutrition on risk of schizophrenia in adulthood using the Chinese famine of 1959-1961 as a natural experiment. Methods: We obtained data from the Second Nationa...

Objectives: To determine the association between sensory impairment and dementia in Chinese older adults. Design: Cross-sectional. Setting: Older adults in 31 provinces of China. Participants: Individuals aged 65 and older (N = 250,752). Measurements: Psychiatrists ascertained dementia based on the International Classification of Diseases,...

Objectives: To investigate the prevalence and associated factors of hearing aid acquisition in Chinese older adults. Methods: We obtained data from a population-based survey on ear and hearing disorders, which was conducted in 4 provinces of China in 2014 to 2015. Trained examiners conducted pure tone audiometry and audiologists further ascertai...

Background: Adults with intellectual disabilities (ID) often have multiple comorbidities. Psychiatric disorders in this population have been poorly studied in developing countries. We aimed to investigate the prevalence of psychiatric disorders in adults with ID and whether comorbid psychiatric disorders were associated with health service utilisa...

Purpose: To estimate the prevalence of, and association between, co-morbid visual and psychiatric disabilities among elderly (>65 years-of-age) persons in China. Methods: Random representative samples were obtained using multistage, stratified, cluster sampling, with probabilities proportional to size. Standard weighting procedures were used to con...

This paper aimed to investigate the role of parental education in child disability in China. We used nationally representative data from China’s National Sample Survey on Disability, iterated twice, in 1987 and 2006, with data of 764,718 children aged 0–14 years. Logit models were used for statistical analysis. Results showed that the prevalence of...

Robust check of independent association of maternal and paternal education with child disability in 1987 and 2006, based on logit models. (DOCX)

The definitions and survey questions for different types of disabilities. (DOCX)

Robust check of association of maternal and paternal education with child disability in 1987 and 2006, by different outcomes. (DOCX)

Visual impairment has become a global challenge, especially for developing countries. This study aims to estimate the prevalence, causes and social factors of visual impairment among Chinese adults. Data were from a nationally representative population-based cross-sectional study. The study population were 1,909,199 non-institutionalized adults age...

Aim: This study explored patterns of service use and associated socioeconomic factors among Chinese elders with mental disabilities. Methods: Data from the second China National Sample Survey on Disability (CNSSD) were used in this study. Univariate and multivariate logistic regression models were used to calculate the odds ratios and 95% confid...

There is limited evidence on the association between socioeconomic status (SES) and autism in developing nations. The aim of this study was to examine this association among children aged 0-17 years in China. We obtained data from the Second National Sample Survey on Disability, and selected 616,940 children for analysis. Autism was ascertained acc...

Objective To investigate trends in rehabilitation services use in children and adolescents with intellectual disabilities and to explore factors potentially contributing to the trends. Design A population-based study using a multistage, randomized, cluster sampling process to ascertain participants in 2006, and a sub-sample was selected for follow...

Epilepsy is the third-leading cause of psychiatry disability in China, and intellectual disability (ID) is also 1 major type of disabilities in China. This study estimates the prevalence of comorbidities with ID and epilepsy-related psychiatry disability (EPD) and examines mutual associations within ID and EPD. Data were taken from the Second China...

Background: Very few studies have explored the association between cigarette or alcohol use and high-risk sexual behaviors (HRSBs) among Chinese youth. Aim: To identify the associations between cigarette and/or alcohol use and HRSBs in unmarried youth 15 to 24 years old in China. Methods: Data were obtained from a nationally representative sur...

Background Very little literature has explored how mental disability in China is connected with inequalities in social and environmental contexts. In the study described herein, we determine whether social-context inequalities were associated with mental disability in China from 1987 to 2006. Methods Data were derived from national representative p...

Objectives: To explore levels and patterns in contraceptive use since the introduction of informed choice in reproductive health services in China since 1994, and to assess the implications of reproductive health service needs among married women of reproductive age in China. Material and methods: Data from Chinese nationwide surveys of family p...

Hearing impairment may affect children’s communication skills, social development, and educational achievement. Little is known about the prevalence of hearing impairment among Chinese children. Data were taken from the 2006 second China National Survey on Disability (CNSD). Hearing impairment was defined as moderate (41-60 dB HL), severe (61-80 dB...

Aim: Cerebral palsy (CP) is the most common cause of motor impairment in childhood. This study aimed to examine the prevalence, severity and concurrent impairments of CP-related motor impairment among Chinese children. Methods: Children with CP-related motor impairment aged 0-17 years were identified through a national population-based survey ba...

Although the prevalence of oral clefts in China is among the highest worldwide, little is known about the prevalence of speech disability associated with cleft palate in Chinese children. The data for this study were collected from the Second China National Sample Survey on Disability, and identification of speech disability associated with cleft p...

Socioeconomic inequalities associated with multiple disabilities have not been explored in China. This is the first study to explore changes in multiple disabilities among persons aged 15–64 years in China. Data were derived from the 1987 and 2006 China National Sample Surveys on Disability, which are nationally representative population-based surv...

The world will be facing huge population aged 65 and older, accounting for 13% of the total population in the future. Significant disabilities rates reflect an accumulation of health risks. Psychiatry disability is one of the most significant disabilities, because it manifests in cognitive, affective, and behavior disorders that limit one's daily l...

This study explores the distribution of sexual orientations and examined disparities by sex and rural and urban residency of non-heterosexual youth, aged 15-24 years, in China. Data was derived from a 2009 nationally representative survey. Among 22288 participants, 0.79% identified as homosexual, 1.47% identified as bisexual, and 4.26% were unsure...

The prevalence of disability has changed along with aggressive economic development in China. However, socioeconomic inequalities associated with cardiovascular disease (CVD)-related disability have not been explored. This is the first study to explore CVD-related disability among persons aged 45 years and older in China. Data were taken from the 2...

Background: The aim of this study was to calculate the prevalence rate of HIV-related sexual risk behaviours (HSRB) among Chinese youth and determine whether there was an association between sexual orientation and HSRB. Methods: This study used a nationally representative survey of youth aged 15-24 years in China. Population numbers, prevalence, an...

Few studies have explored how mental disabilities have changed with the waves of Chinese social reforms that occurred between 1912 and 2006. The present study evaluated population-based data from the Second China National Sample Survey on Disability to investigate these trends and their effects on mental disabilities. The Cox proportional hazards m...

Background Increased life expectancy is accompanied by an increased burden of disability. However, few large-scale studies have assessed mortality in people with disabilities, especially in developing countries. Here we describe mortality patterns in a nationally representative cohort of people with disabilities and identify factors that contribute...

Background: Demand for healthcare services among older population is expected to rise, especially among those living with disabilities. This study aims to estimate the prevalence rate and identify the factors associated with healthcare service use among Chinese elderly with disabilities. Methods: This study employed a nationally representative s...

Some phenomena that occur in the present day may have also occurred a long time ago. In this study, we examined the relationship between education attainment and late marriage in modern society as well as in ancient China. To this end, we analyzed demographic data reported by 2010 Census statistics and data recorded by historical documents of Chine...