Chandrika Konwar- PhD
- PhD Student at University of Delhi
Chandrika Konwar
- PhD
- PhD Student at University of Delhi
About
6
Publications
894
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32
Citations
Introduction
Current institution
Additional affiliations
September 2022 - June 2023
Education
July 2016 - July 2018
July 2013 - July 2016
Publications
Publications (6)
Aging is the process of gradual physio-biochemical deterioration. While aging is inevitable, healthy aging is the key to individual and communal well-being. Therefore, it is essential to understand the regulation of aging. SIN-3/Sin3 is a unique regulatory protein that regulates aging without DNA binding activity. It functions by establishing multi...
Neisseria gonorrhoeae (NG), the causative organism of gonorrhea, has been classified by the World Health Organization as ‘Priority’ two organism owing to its increased resistance to antibiotics and even failure of recommended dual therapy with ceftriaxone and azithromycin. As a result, the general and reproductive health of infected individuals is...
SIN3/HDAC is a multi-protein complex that acts as a regulatory unit and functions as a co-repressor/co-activator and a general transcription factor. SIN3 acts as a scaffold in the complex, binding directly to HDAC1/2 and other proteins and plays crucial roles in regulating apoptosis, differentiation, cell proliferation, development, and cell cycle....
Background
Antimicrobial resistance in Neisseria gonorrhoeae (NG), the causative organism of gonorrhea, has posed a serious threat worldwide. Gonorrhea is a sexually transmitted disease with a high morbidity burden and is an important cause of pelvic inflammatory disease. The failure of recommended dual therapy with ceftriaxone and azithromycin has...
Background
Neisseria gonorrhoeae (NG) is a sexually transmitted pathogen infecting both men and women. In spite of a number of antibiotics, gonorrhea (also known as “The Clap”), remains a frequently reported STI and is an important cause of pelvic inflammatory disease and infertility. Due to resistance to most of the currently used drugs, NG has be...
Increasing drug resistance in pathogens including Mycobacterium tuberculosis (MTB) has been ascribed to mutations in the known target genes. However, many of these drugs have multiple targets; some of which have not been identified so far. Understanding the mechanism of action of these drugs holds a great promise in better management of disease esp...
