Chandra Kumar Natarajan- MBBS, MD, DNB, DM, DNB
- Head of the Department at Kanchi Kamakoti Childs Trust Hospital
Chandra Kumar Natarajan
- MBBS, MD, DNB, DM, DNB
- Head of the Department at Kanchi Kamakoti Childs Trust Hospital
About
34
Publications
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Introduction
Current institution
Additional affiliations
December 2015 - February 2016
January 2010 - December 2012
April 2005 - December 2005
Publications
Publications (34)
Purpose: The optimal method to estimate ideal depth of insertion of endotracheal tube in neonates is still under question. With increasing evidence that TOCHEN formula is unreliable in ELBW neonates, it is being replaced by Nasotragal Length (NTL) based formulae and standardized weight-based charts. Objective: (i) To compare NTL (NTL+1 cm) and TOCH...
A neonate born of third-degree consanguineous marriage presented on day 12 of life with congestive cardiac failure. A male sibling died at 3 months of age, cause of which was not known. He was treated with decongestive measures and multiple inotropes. 2D Echocardiogram revealed severe Left ventricular dysfunction with prominent trabeculations and d...
Objective:
To study the correlation of objective parameters for diagnosing shock viz., perfusion index (PI), plethysmography variability index (PVI) and serum lactate (SL) with invasive blood pressure in late preterm and term infants with shock.
Methods:
Prospective observational study (diagnostic test) conducted at the neonatal intensive care u...
Objectives:
To study the survival rates at discharge and neurodevelopmental outcome at 1 y of corrected age (CA) of extremely-low-birth-weight ELBW neonates.
Methods:
This prospective, descriptive study was conducted in a tertiary care level III extramural NICU of a teaching hospital. Forty-nine extremely-low-birth-weight (ELBW) neonates were en...
Background
DiGeorge Syndrome (DGS) is caused by the 22q11 deletion. There is wide variation in the phenotypic presentation due to incomplete penetrance. Since dysmorphism is subtle in neonates, a high index of suspicion should be kept.
Clinical Description
A 2.8 kg term baby girl born of a cesarean section developed stridor and respiratory distres...
9 day old term baby girl was referred at day 9 of illness to our tertiary Covid neonatal intensive care unit with prenatal exposure to SARS Cov2 infection. She had progressive respiratory distress and hypoxia needing invasive ventilation and developed features of severe pneumonia needing steroids and intravenous immunoglobulin. Baby also developed...
Background
Feeding problems are common in preterm neonates of which desaturation during direct feeding is a known entity. However, term newborns have acceptable range of fall in saturation while feeding directly. Here, we report a term newborn with dysmorphic features had desaturation during feeding.
Clinical Description
A male baby born to second...
Among 1713 neonates, SARS-CoV-2 infection status was available for 1330 intramural and 104 extramural neonates. SARS-CoV-2 positivity was reported in 144 intramural and 39 extramural neonates. Perinatal transmission occurred in 106 (8%) and horizontal transmission in 21 (1.5%) intramural neonates. Neonates roomed-in with mother had higher transmiss...
Background
Limited evidence exists on perinatal transmission and outcomes of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in neonates.Objective
To describe clinical outcomes and risk factors for transmission in neonates born to mothers with perinatal SARS-CoV-2 infection.DesignProspective cohort of suspected and confirmed...
Objectives:
To evaluate the prognostic value of amplitude-integrated EEG in term neonates with encephalopathy.
Methods:
In this prospective observational study we enrolled 58 term neonates with encephalopathy from March, 2019 to March, 2020. Level of alertness was ascertained as per Volpe's classification and tone as per Amiel-Tison scale of ton...
Background: Complex injury to the esophagus, trachea, and tracheoesophageal fistula in a case of esophageal atresia is rarely reported that requires prompt identification and management.
Case Presentation: A very-low-birth-weight preterm with a tracheoesophageal fistula on ventilatory support for respiratory distress syndrome was transferred to ou...
Very-low-birth-weight preterm with a tracheoesophageal fistula on
ventilatory support for respiratory distress syndrome developed a complex tracheoesophageal injury to the esophagus, trachea during emergency intubation to control large air leak through the fistula. The baby survived following repair of the injury and TEF
Background: Double simultaneous intussusception is a peculiar and rare variety of intussusception with only 3 previously reported neonatal cases.
Case presentation: A 15-day-old male neonate with respiratory distress was found to have Tetralogy of Fallot and hypoplastic pulmonary stenosis. Small bowel intussusception was diagnosed on ultrasound ab...
Objective:
To investigate the safety and efficacy of goat lung surfactant extract (GLSE) compared with bovine surfactant extract (beractant; Survanta®, AbbVie, USA) for the treatment of neonatal respiratory distress syndrome (RDS).
Study design:
We conducted a double-blind, non-inferiority, randomized trial in seven Indian centers between June 2...
Objective
To evaluate the feeding performance of infants with bronchopulmonary dysplasia (BPD) on paladai.
Methods
This cross-sectional study was performed in a level III neonatal unit in North India from March through August 2012. Nineteen infants (27–32 wk of gestation) were enrolled; 9 in BPD group (oxygen requirement for at least 28 d) and 10...
Objective:
To the efficacy of daily assisted physical exercise (starting from one week of postnatal age) on bone strength at 40 weeks of post menstrual age to no intervention in infants born between 27 and 34 weeks of gestation.
Design:
Open-label randomized controlled trial.
Setting:
Tertiary-care teaching hospital in northern India from 16 M...
Background: Evidence on the optimal time to initiation of complementary feeding in preterm infants is scarce. We examined the effect of initiation of complementary feeding at 4 months versus 6 months of corrected age on weight for age at 12 months corrected age in preterm infants less than 34 weeks of gestation.
Methods: In this open-label, randomi...
Background:
Sepsis is one of the most common causes of neonatal deaths globally. Most sepsis-related deaths occur in low-income and middle-income countries, where the epidemiology of neonatal sepsis remains poorly understood. Most of these countries lack proper surveillance networks, hampering accurate assessment of the burden of sepsis, implement...
Meconium aspiration syndrome (MAS), a common cause of respiratory failure in neonates, is associated with high mortality and morbidity. The objectives of this review were to evaluate the effects of administration of (a) surfactant - either as lung lavage (SLL) or bolus surfactant (BS) and (b) antibiotics on mortality and severe morbidities in neona...
About 99% of neonatal deaths occur in low- and middle-income countries. There is a paucity of information on the exact timing of neonatal deaths in these settings. The objective of this review was to determine the timing of overall and cause-specific neonatal deaths in developing country settings. We searched MEDLINE via PubMed, Cochrane CENTRAL, W...
This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the effect and safety of initiation of complementary feeding (defined as semi-solid, soft or solid foods other than breast or animal milk and infant/follow-on formula) to preterm infants (less than 37 weeks postmenstrual age (PMA) at birth) at or...
To compare the effect of 800 vs 400 IU of daily oral vitamin D3 on the prevalence of vitamin D deficiency (VDD) at 40 weeks' postmenstrual age (PMA) in preterm infants of 28 to 34 weeks' gestation.
In this randomized double-blind trial, we allocated eligible infants to receive either 800 or 400 IU of vitamin D3 per day (n = 48 in both groups). Prim...
To determine delivered O2 concentration (dFiO2 ) during manual inflations using neonatal self-inflating resuscitation bags (SIBs) at oxygen (O2 ) flow rates <1 L/min.
This experimental study, determined dFiO2 during 216 sets of manual inflations at different O2 flow rate (L/min; 0.2, 0.4, 0.6, 0.8, 1.0 and 5.0), controlling peak inspiratory pressur...
Tumoral calcinosis is a rare disorder of mineral metabolism among adolescents and young adults characterized by deposition of calcific masses around large joints. It is less commonly reported in pediatric population and commonly mistaken for bone tumors. Typical lab parameters include hyperphosphatemia with normal levels of serum calcium, parathyro...
