Catherine Maurice

Catherine Maurice
University Health Network | UHN · Department of Neurology

About

118
Publications
6,363
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393
Citations
Citations since 2016
107 Research Items
359 Citations
20162017201820192020202120220204060
20162017201820192020202120220204060
20162017201820192020202120220204060
20162017201820192020202120220204060
Introduction
Skills and Expertise

Publications

Publications (118)
Article
Objective To determine the prevalence of cerebrospinal fluid (CSF) markers associated with inflammation (i.e., elevated white blood cell count, protein concentration, and CSF-specific oligoclonal bands) in patients with early active autoimmune encephalitis (AE). Methods CSF characteristics, including WBC count, protein concentration, and oligoclon...
Article
Over the past two decades, there has been a fundamental shift away from traditional cytotoxic chemotherapy towards the identification, and subsequent suppression of specific oncogenes. Immunotherapy and targeted therapy prime the immune system, potentially leading to deleterious side effects. The following case of Guillain-Barré Syndrome (GBS) emph...
Chapter
Patients presenting for headache often worry about having a brain tumour. Specific tumours may induce headache by varied mechanisms, producing different phenotypes. Virtually all headache and facial pain phenotypes can be secondary to a brain tumour, but clinical clues to a secondary aetiology are often present. Headaches may also be related to the...
Article
In: ACTA SCIENTIFIC CANCER BIOLOGY (ISSN: 2582-4473) Keywords: PML Progressive Multifocal Leukoencephalopathy; JC Virus; Leukemia; ATRA; Maintenance Chemotherapy; ATO (Arsenic Trioxide); Immunosuppression; Myoclonus We describe a case of progressive multifocal leukoencephalopathy (PML) in a patient on maintenance chemotherapy for high-risk acute pr...
Article
In an era dominated by high-yield technology and novel therapies, a clinician’s insight and mindful reasoning remain more powerful than fine point instruments. During the course of our medical training, we are taught to consider the most prevalent aetiologies upfront, since « frequent conditions are widespread ». Moreover, we are trained to develop...
Article
Background: Patients with cancer who are treated with immune checkpoint modulators (ICMs) have their health-related quality of life (HRQOL) measured using general patient-reported outcome (PRO) tools. To the authors' knowledge, no instrument has been developed to date specifically for patients treated with ICMs. The objective of the current study...
Article
This manuscript discusses the situation we will face in a near future, when several therapeutic molecules will emerge from clinical trials and we will only rely on our judgment to determine the best clinical practice. Open access
Article
Published in: Journal of Clinical Research and Reports A lymphoma survivor presented for reassessment of his long-standing neurological symptoms more than three decades following a diagnosis of systemic T-cell lymphoma. Despite our desire to establish the diagnosis promptly, time is often necessary to reach conclusions based on the patient's clinic...
Article
Full-text available
A lymphoma survivor presented for reassessment of his long-standing neurological symptoms more than three decades following a diagnosis of systemic T-cell lymphoma. Despite our desire to establish the diagnosis promptly, time is often necessary to reach conclusions based on the patient’s clinical evolution. We recount the chronology of clinical and...
Article
Full-text available
A thirty-one year-old Sri Lankan man presented with a two-month history of progressive pan-cerebellar syndrome, following allogeneic stem cell transplantation. This curative-intent therapy was performed in the context of an underlying acute myeloid leukemia. During the post-transplant period, patients are extremely vulnerable, especially due to the...
Conference Paper
It is estimated that thirty to forty percent of all cancers can be prevented by lifestyle and dietary measures alone. The main goal is to potentially interfere with the development of precancerous tumors. Even healthy people have a certain number of latent cancerous cells in their tissues. Spontaneous formation of small tumors happens frequently ov...
Conference Paper
AFAF Presentation: Association des Femmes d'Affaires Francophones de l'Ontario
Article
Low-grade serous ovarian cancer, representing 10% of all ovarian cancer diagnoses, is renown for its poor response rate to chemotherapy, despite its indolent course. The MILO study is an international, randomized phase III trial comparing binimetinib, a targeted agent, to standard chemotherapy in patients diagnosed with low-grade serous ovarian can...
Article
Introduction: Large fiber neuropathy is rare in neurofibromatosis type 1, but small fiber neuropathy has not been studied. Methods: Patients with neurofibromatosis Type 1 underwent nerve conduction studies for large fiber assessment. Small fiber tests included: quantitative thermal thresholds, laser Doppler flare imaging, intra-epidermal nerve f...
Chapter
Current Status: In Production - Updated July 20th, 2019. Individual volumes in the series are published in concurrent print and online versions. The Oxford Textbooks in Clinical Neurology is a series of authoritative, evidence-based volumes in areas of specific interest to neurology trainees and consultants. The books incorporate evidence-based pra...
Article
Particularity of Coagulation Disorders in Brain Tumour Patients & Key Points to Optimize Management & Pathophysiology and Clinical Update + Expert Opinion.
Article
Full-text available
Purpose Patients with brain tumors face unique quality of life challenges. Executive dysfunction is common and functionally limiting, with no established treatments as standard care. This pilot study evaluated the efficacy of Goal Management Training (GMT), a behavioral intervention combining mindfulness and strategy training, for improving executi...
Presentation
https://imagehttps://images.radio-canada.ca/w_635,h_357/v1/ici-premiere/16x9/ypdmp-catherine-maurice-dre-neuro-oncologue.jpegs.radio-canada.ca/w_635,h_357/v1/ici-premiere/16x9/ypdmp-catherine-maurice-dre-neuro-oncologue.jpeg
Data
Poster Presentation. See Poster Attached.
Data
Poster Presentation. See Poster Attached.
Data
Poster Presentation. See Poster Attached.
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Poster Presentation. See Poster.
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Poster Presentation. See Poster Attached.
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Poster Presentation. See Poster Attached.
Data
Cabrera S, Maurice C, Mason WP. Chapter 137: Low grade and anaplastic oligodendroglioma. In: R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri, Editors. International Neurology. John Wiley and Sons. Published Online First: April 22nd, 2016. Hoboken (New Jersey, USA): Second Edition; 2016. P. 567-571. Doi: 10.1002/9781118777329.ch137. http...
Conference Paper
Abstract: Small Fiber Polyneuropathy in Patients with Neurofibromatosis, Type 1. Presenter(s): Bril V, Abrham A, Kim R, Maurice C, Zadeh G, Kongkham P, Barnett C. Poster presentation + publication at the American Academy of Neurology 70th Annual Meeting, April 21-27, 2018, Los Angeles, CA, USA. Platform ID at the AAN Meeting: S31. Therapeutics, Phe...
Article
Maurice C, Grant K, Pereira AM, Abulhasan YB (2018) Vulnerability of Parkinson Patients to Iatrogenic Adverse Events: Emphasis on the Perioperative Period through a Case Report. J Neurol Neurocrit Care, Volume 1(2): 3–3, 2018. http://file:///Users/catherinemaurice/Downloads/JNNC-18-107_Catherine-Maurice.pdf Journal of Neurology and Neurocritical C...
Conference Paper
ABSTRACT Sensitivity of Cell Count and Protein in Cerebrospinal Fluid for the Diagnosis of Autoimmune Encephalitis Julien Hebert1 , Priti Gros1 , Sarah Lapointe2 , Claude Steriade3 , Gregory S. Day4 , Catherine Maurice2 , Richard A. Wennberg5,6, David F. Tang-Wai5,6 1 Neurology, University of Toronto, 2 Princess Margaret Cancer Centre, Toronto, Ca...
Article
Full-text available
A patient with pilomotor seizures post anti‐LGI1 limbic encephalitis, refractory to immunotherapy and anti‐epileptic drugs, was investigated with electroencephalography and magnetoencephalography. Seizures occurred daily (14.9 ± 4.9/day), with catamenial exacerbation, inducible by hyperventilation. Anterior temporal ictal onsets were heralded (by ~...
Article
Full-text available
BACKGROUND Glioblastoma is the most common adult malignant glioma, with poor prognosis and adverse neurological sequelae. Physical activity improves outcomes in patients with other cancers, but has not been evaluated in GBM. This prospective, single-arm intervention trial examines feasibility and preliminary efficacy of exercise on progression-free...
Poster
Brain Sciences 2.57: Journal Cite Score. (ISSN 2076-3425; CODEN: BSRCCS) is an international peer-reviewed open access journal on neuroscience published monthly online by MDPI. P114 Quality of Life in Adults with NF1 and NF2 Attending a Specialized Neurofibromatosis Clinic in Toronto, Canada. ROOM 8 Sunday 04 November 2018 | 17:25 - 18:55 AbsID: N...
Conference Paper
113 | Evidence of Small Fibre Neuropathy in Neurofibromatosis Type 1 http://www.nf-paris2018.com/ Sunday 04 November 2018 | 17:25 - 18:55 ROOM 8 Sunday 04 November 2018 Joint Global Neurofibromatosis Conference Combining: 2018 Children’s Tumor Foundation NF Conference/18th European Neurofibromatosis Meeting/2018 Schwannomatosis and NF2 State of Ar...
Conference Paper
Quality of Life in Adults with NF1 and NF2 Attending a Specialized Neurofibromatosis Clinic in Toronto, Canada. Joint Global Neurofibromatosis Conference Combining: 2018 Children’s Tumor Foundation NF Conference/18th European Neurofibromatosis Meeting/2018 Schwannomatosis and NF2 State of Art. Maison de la Chimie, Paris, France. Presenters: Hamoy-J...
Conference Paper
“Bevacizumab and Acoustic Neuroma: What is Known, Debated and Expected?” In Collaboration With the Acoustic Neuroma Association of Canada. Published Online: November 27th, 2018. Conference: Symposium: September 29th, 2018. www.anac.ca https://www.anac.ca/2018-symposium-video-4-of-10 Copyright © 2019 Acoustic Neuroma Association of Canada Charity Re...
Conference Paper
Supervision of: Kiran Grant, 2nd year Medical Student, and Austin Pereira, 3rd year Medical Student, University of Toronto and MD Candidate Promotion 2022 and 2021 respective Session: Innovative Techniques and Advancements in Neuro-Oncology. Format: Oral presentation + Poster + Publication in J Neurol Disord. Conference Paper. Conference: 3rd Inter...
Conference Paper
The challenge of treating neurologic complications in the era of immunotherapy. Maurice C, Grant K. J Neurol Disord. 2018, Sep; Volume 6, Published Online First: 14 September 2018. DOI: 10.4172/2329-6895-C7-043. Conference abstract. J Neurol Disord https://doi.org/10.4172%2F2329-6895-c7-043 https://www.omicsonline.org/proceedings/the-challenge-of-t...
Technical Report
Development of Comprehensive Education and Awareness Strategy about Leptomeningeal Disease, Continuing Education, Faculty of Medicine, Department of Medicine. The Educational material includes pamphlets, webpages, videos, eLearning modules and a print campaign. To be continued in 2017. Project realized in collaboration with the Traub family. Form:...
Article
ISSN: 2474-1655 New Onset Obsessive-Compulsive Disorder Post Cingulate Surgery for Refractory Epilepsy. Gheorghe A, Chamelian L, Pereira A, Maurice C. Ann Clin Case Rep. 2018; 3:1541. Published Online First: August 25th, 2018. ISSN: 2474.1655
Article
Full-text available
Patients presenting with acute or chronic hepatopathy can develop altered mental status with psychomotor slowing, most commonly indicating encephalopathy. We present the case of a 56-year-old patient who developed subacute atypical neuropsychiatric symptoms including cognitive and behavioural disorganization, manic-like state, and lateralized parki...
Presentation
“Teaching Without Borders – Médecins Sans Frontières – Humanitarian Project.” Meet The Teachers Session, Neurology Rounds, June 21st, 2018. Krembil Research Center, University of Toronto, Ontario, Canada.
Conference Paper
Full-text available
Background: Glioblastoma is the most common adult malignant glioma, with poor prognosis and adverse neurological sequelae. Physical activity improves outcomes in patients with other cancers, but has not been evaluated in GBM. This prospective, single-arm intervention trial examines feasibility and preliminary efficacy of exercise on PFS, cognition...
Conference Paper
Full-text available
Background: Brain tumors present unique challenges to patient and family quality of life (QOL). Cognitive dysfunction is common and functionally limiting, with no established treatments. These studies evaluate feasibility and preliminary efficacy of behavioral interventions developed for neuro-oncology patients. Study 1: A randomized controlled tri...
Conference Paper
Abstract 4232 111 Cerebellar Ataxia Following Allogenic Stem Cell Transplant: A Clinical Approach to a Differential Diagnosis. Section P6. Case based Neuro-oncology: The Art and Power of Clinical Observation. Pereira AM, Pereira AK, Mason WP, Maurice C. Publication online on the AAN Meeting Website. American Academy of Neurology 70th Annual Meeting...
Presentation
Medical Management of NF-1 Related Tumors, Elisabeth Raab Lectureship in NF, Krembil Research Center, Toronto Western Hospital, West Wing Auditorium 2-401, University of Toronto, Toronto, Canada.
Method
Collaboration to algorithm redaction as neuro-oncology consultant. PI CAR T CELL Trials UHN: DR C Chen. Combined effort of Hematologic Malignancy Specialists/Neuro-Oncology/Clinical Trials Team Involved in CAR T Cell / CARTOX Trials. Tool available to the public on UHN Research Online ARP 2018 Version 1 - Protocol 17.3.1 Adapted from MD Anderson CA...
Method
Algorithm/Template Creation with the multidisciplinary "CAR T Cell Trials Team". PI: Dr. C Chen Tool available to the public UHN Research Website x APR 2018. Peer-Reviewed. Adapted from MD Anderson CAR Cell Therapy Toxicity Assessment.
Method
Protocol/Algorithm Designed for the CAR T Cell Trials at UHN PI Dr. C. Chen Collaborative effort of the multidisciplinary CAR T Cell Trial Team. Role: Neuro-Oncology Expert Consultant. Adapted from MD Anderson CAR Cell Therapy Toxicity Assessment.
Article
Lim Fat, M., Maurice, C., Maganti, M., & Mason, W. (2018). Bevacizumab in Recurrent High-Grade Gliomas: A Canadian Retrospective Study. Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques, 45(1), 56-61. doi:10.1017/cjn.2017.248. DOI: 10.1017/cjn.2017.248 [Indexed for MEDLINE] PMID: 29151389 https://www.ncbi.nlm.n...
Article
Full-text available
Adult-Onset Anti-N-methyl-D-aspartate-receptor Encephalitis Presenting as a Non-Fluent Aphasia - Julien Hébert, Farah El-Sadi, Catherine Maurice, Richard A. Wennberg, David F. Tang-Wai
Article
Full-text available
Objectives: Glioblastoma is a lethal disease in the elderly population. We aimed to evaluate disease and treatment outcomes in the oldest-old patients. Methods: Patients >80 years old with histologically confirmed glioblastoma treated between 2004 and 2009 were identified. We included patients managed with best supportive care (BSC), temozolomid...
Article
Full-text available
Background: Bevacizumab has been used in recurrent glioblastoma (rGBM) since 2010 in Canada. Given its cost, potential toxicities, and unclear efficacy, further studies are required to better define suitable candidates for therapy. Methods: A single-center retrospective review of patients started on bevacizumab for rGBM from 2012 to 2015 was per...
Method
In Collaboration with Chris Coltman - Elyptic and Michael Nadel. Demonstration of an upcoming game from Elyptic Production : "Rounds". Developed in Unreal Engine 4 and rendered in real time. 4. “An Intro To Rounds.” Demo/Pilot Project Published Online September 20th, 2017. Ongoing project, awaiting financial support/sponsorship. In collaboration wi...
Article
Full-text available
Elevated neutrophil–lymphocyte ratio (NLR) may predict worse outcomes in cancer, including glioblastoma (GBM). This study assessed whether change in NLR during focal radiotherapy and concomitant temozolomide (RT-TMZ) provides further prognostic information. This was a retrospective review of patients treated with RT-TMZ for histologically confirmed...
Presentation
https://vimeo.com/313494937 What Neurologists Do For Fun?... They Play Neurobowl!!! Neurobowl Boston American Academy of Neurology 2017
Chapter
Long heralded as a key guide for medical students, nurses, and allied health professionals, the Essentials of Clinical Examination Handbook, Eighth Edition is a concise yet comprehensive on-the-job reference for history-taking and physical examination, which covers both standard exams and specialty-specific diagnostic approaches. The Handbook has b...
Presentation
Dr. Catherine Maurice, Dr. Catherine Maurice, Neuro-Oncologist, University Health Network, Toronto, ON, presented “A New Era in the Treatment of Brain Tumours” as part of the Join The Movement to End Brain Tumours - National Conference, in Toronto, on Saturday, October 22, 2016. This presentation focuses on the current standard of care for the trea...
Presentation
Neurological Aspects of HSV Encephalitis. Internal Medicine Grand Rounds, Toronto Western Hospital. Toronto, Ontario, Canada. Oral Presentations. Case presentation. (Continuing Education).
Presentation
1 hour special course for members of the Tumor Immunotherapy Program of Princess Margaret Cancer Centre. Tumor Immunotherapy Program, Princess Margaret Hospital. Toronto, Ontario, Canada. Oral Presentation.
Conference Paper
High Risk Breast Cancer Screening in Women with Neurofibromatosis Type 1. 14th International Congress on Neuromuscular Diseases. Toronto, Ontario, Canada. Presenter(s): Jeanna McCuaig, Shelley Westergard, Catherine Maurice, Paul Kongkham, Gelareh Zadeh, Carolina Barnett-Tapia, Vera Bril, Raymond Kim. Poster Presentation. July 5-9th 2016. McCuaig J,...
Conference Paper
Albdali M, Bril V, Maurice C. Myasthenia Gravis Induced By A MEK Inhibitor: First Case Reported. Journal of Neuromuscular Diseases. 2016 Jul;3(S1):S1-S232. Abstract #237, S199 DOI: 10.3233/JND-160001 PMID: 27854235 https://doi.org/10.3233%2Fjnd-160001 Poster Presentation + Abstract Associated; Abstract #237, S199

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