Cassandra A Ocampo

University of Botswana | UB · Faculty of Medicine

Objective The first international consensus criteria for optic neuritis (ICON) were published in 2022. We applied these criteria to a prospective, global observational study of acute optic neuritis (ON). Methods We included 160 patients with a first‐ever acute ON suggestive of a demyelinating CNS disease from the Acute Optic Neuritis Network (ACON...

Rehabilitation Robots for Neurorehabilitation in High, Low, and Middle Income Countries: Current Practice, Barriers, and Future Directions describes the state-of-art research of stroke rehabilitation using robot systems in selected High Income Countries (HICs) and Low and Middle Income Countries (LMICs), along with potential solutions that enable t...

Stroke is the second leading cause of death worldwide. The burden of disability after a stroke is also large, and is increasing at a faster pace in low-income and middle-income countries than in high-income countries. Alarmingly, the incidence of stroke is increasing in young and middle-aged people (ie, age <55 years) globally. Should these trends...

Optic neuritis (ON) often occurs at the presentation of multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD). The recommended treatment of high-dose corticosteroids for ON is based on a North American study population, which did not address treatm...

Background: The growing burden of Parkinson's disease (PD) in Africa necessitates the identification of available therapies and services to improve patient care. Objective: To investigate the availability, affordability, frequency of usage, and insurance coverage of PD therapies (pharmacological, surgical, physical, and speech therapies) and ser...

Objective To estimate the prevalence of Vitamin B12 deficiency among patients with diabetes. Methodology This cross-sectional study was undertaken on 351 patients with diabetes at a specialised public diabetes clinic in Gaborone between July 2017 and October 2017. Clinical, anthropometry and laboratory data were collected. Vitamin B12 deficiency w...

Background: Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia associated with high morbidity and mortality rates. Notwithstanding the scale of the problem, there are sparse data on the characteristics and outcomes of both valvular and non-valvular AF patients in sub-Saharan Africa (SSA). Objective: This study aimed at descri...

Hydatid disease (echinococcosis) is a zoonotic parasitic disease of humans and is of significant medical importance in most countries of the world. We share images from the case of a 23-year-old lady with pulmonary hydatid cyst disease, which ruptured into the bronchial airways within two months of commencing albendazole therapy. She was managed c...

Huntington’s disease-like 2 (HDL2) is a rare autosomal dominant progressive neurodegenerative disorder commonly seen in adults. It was first described in a large African-American family in the United States. HDL2 clinically resembles Huntington’s disease (HD) and causes adult-onset relentlessly progressive movement, emotional and cognitive dysfunct...

Background: Pernicious anaemia (PA) describes megaloblastic anaemia resulting from cobalamin deficiency that is due to the absence of intrinsic factor (IF). Most cases are autoimmune in origin, with antibodies to parietal cells, IF or the cobalamin – IF complex.Methods: We report the clinical features, investigation and treatment of a patient in wh...