Casimiro Javierre

Casimiro Javierre
University of Barcelona | UB · Departament de Ciències Fisiològiques

Doctor of Medicine

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184
Publications
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2,435
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Publications

Publications (184)
Article
Full-text available
Purpose The present study aims to evaluate the effects of intermittent sequential pneumatic compression (ISPC) in the short-term recovery of a repeated sprint interval exercise, including the assessment of power output performance, hematocrit, legs water, and perceptual recovery. Methods A randomized, counterbalanced, crossover design was conducte...
Article
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Purpose Intermittent pneumatic compression (IPC) applies gradual pressure to facilitate lymph and blood flow movement to reduce exercise-induced tissue fluid accumulation and plasma volume loss. This study aimed to evaluate the cardiovascular system response during the recovery with IPC compared with passive recovery (Sham). Methods Sixteen volunt...
Article
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Introduction: Lung diffusion capacity of carbon monoxide (DLCO) provides a measure of gas transfer in the lungs, which increase in relation to exercise and decrease in the presence of lung interstitial disease. The aim of this study is to evaluate the changes in lung diffusion after anaerobic and aerobic exercise in a cycle ergometer. Material and...
Article
Pulse arrival times (PAT) are time intervals between the electrocardiogram (ECG) and an arterial pulse wave (APW) widely used to obtain cuffless blood pressure. Although some distal APW’s can be easily measured using, for example, a photoplethysmography (PPG) sensor on a finger, proximal APW’s, such as the one of the carotid in the neck, are much m...
Article
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Introduction: The genetic disorder causing Down syndrome (DS) affects the cardiorespiratory and hemodynamic parameters. When exercising, sufficient blood flow is necessary for active muscles. Cardiac output (Q) must be proportional to the peripheral requirements. In case the stroke volume (SV) is lower, the heart rate (HR) will increase further in...
Article
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Universal exercise recommendations for adults neglect individual preferences, changing constraints, and their potential impact on associated health benefits. A recent proposal suggests replacing the standardized World Health Organisation (WHO) exercise recommendations for healthy adults by co-designed interventions where individuals participate act...
Article
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(1) Background: half-marathon races are popular among recreational runners, with increases in participation among middle-aged and women. We aimed to determine the effects of two half-marathon training programs on hematological and biochemical markers in middle-aged female recreational runners; (2) Methods: ten women (40 ± 7 years) followed moderate...
Article
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The presence of missing data and small sample sizes are very common in social and health sciences. Concurrently to present a methodology to solve the small sample size and missing data, we aim to present a definition of Cognitive Reserve for people with Down Syndrome. This population has become an appealing focus to study this concept because of th...
Article
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Introduction: Down syndrome (DS) is a chromosomal disorder affecting simultaneously cardiovascular and respiratory systems. There is no research studying the coupling between these systems during cardiorespiratory exercise testing in a population with DS. Cardiorespiratory coordination (CRC), evaluated through principal component analysis (PCA), me...
Article
Full-text available
Introduction: Down syndrome (DS) is a chromosomal disorder affecting simultaneously cardiovascular and respiratory systems. There is no research studying the coupling between these systems during cardiorespiratory exercise testing in a population with DS. Cardiorespiratory coordination (CRC), evaluated through principal component analysis (PCA), me...
Article
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Purpose: To compare inter-individual response variability and detraining effects on markers attributed to aerobic and anaerobic performance after short-term standardized aerobic, strength and mixed training programs. Methods: Thirty-six male students were randomly assigned to either an aerobic, strength, mixed, or control program (9 per group). T...
Article
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Physical exercise is known to have a dose-dependent effect on the immune system and can result in an inflammatory process in athletes that is proportional to the intensity and duration of exertion. This inflammatory process can be measured by cell markers such as dendritic cells (DCs), which, in humans, consist of the myeloid DC (mDCs) and plasmacy...
Article
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García, Iker, Franchek Drobnic, Casimiro Javierre, Victoria Pons, and Ginés Viscor. Severe hypoxic exercise does not impair lung diffusion in elite swimmers. High Alt Med Biol 00:000-000, 2020. Background: Exercise performed at high altitude may cause a subclinical pulmonary interstitial edema that can worsen gas exchange function. This study aime...
Article
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We applied Symbolic Transfer Entropy (STE) for the detection of directed couplings between pulmonary variables registered during repeated progressive and maximal cardiopulmonary exercise tests (CPET). We verified the hypothesis whether, effort accumulation has impact on the decrease of the level of coupling between ventilation (VEbtps), fraction of...
Article
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A crucial subject in sports is identifying the inter-individual variation in response to training, which would allow creating individualized pre-training schedules, improving runner’s performance. We aimed to analyze heterogeneity in individual responses to two half-marathon training programs differing in running volume and intensity in middle-aged...
Article
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Introduction: Maximal oxygen uptake (VO2) may be one of the most important variables in the study of the responses of people with spinal cord injury (SCI) and without SCI to physical exercise. The results achieved during its assessment serve as a diagnostic and health indicator in clinical settings. Objective: this study aimed to investigate the ph...
Article
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Background: People with intellectual disabilities (ID) have low levels of physical activity (PA) together with accelerated aging profiles. Adherence to PA interventions for persons with ID is low based on barriers such as motivation. The IDEA study aims to determine the effect of two types of exercise programs, continuous aerobic (CAEP) vs sprint...
Article
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Purpose: To test the effectiveness on recreational female middle-aged runners of a programme of high-intensity interval training (HIIT) for a half-marathon race contrasted to a conventional moderate-intensity continuous training (MICT). Methods: Twenty recreational female runners (40 ± 7 years) followed MICT or HIIT schedules for training a half-ma...
Article
This study used time to exhaustion (TTE) to predict V̇O2max in female recreational master runners. Forty-two middle-aged women (mean = 40.5 ± 5.9 years) who had trained for recreational running performed two Université de Montréal Track Tests in the facilities of the University of Barcelona (Spain). The first was performed on a treadmill (t), the s...
Article
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Several studies have investigated the effects of fat intake before exercise on subsequent substrate oxidation and exercise performance. While some studies have reported that unsaturated fatty acid supplementation slightly increases fat oxidation, the changes have not been reflected in the maximum oxygen uptake or in other performance and physiologi...
Article
BACKGROUND As the result of population aging, hematologists increasingly face the challenge of effectively managing older adults with oncological diseases. The heterogeneity of the aging process means that chronological age does not serve as a pivotal variable on which the clinical or treatment decisions are based. To improve outcomes in older popu...
Article
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Objective: Our purpose was applying a principal component analysis (PCA) approach to cardiorespiratory exercise testing evaluation and test its sensitivity to workload accumulation. Approach: Twenty-five healthy young adults performed a progressive and maximal cycling test which was divided into two parts: moderate and high workload intensities,...
Article
Background Since the 1980s the role of tryptophan in modulating fatigue has been the subject of debate. According to some models, tryptophan delays the onset of fatigue. Conversely, in other models, this amino acid is implicated in generating fatigue. This study attempts to shed some light on the debate. Method Ten elite (non-professional) road ra...
Article
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In recent years, the incidence of frostbite has increased among healthy young adults who practice winter sports (skiing, mountaineering, ice climbing and technical climbing/alpinism) at both the professional and amateur levels. Moreover, given that the population most frequently affected is healthy and active, frostbite supposes a substantial inter...
Article
Carceller, Anna, Casimiro Javierre, Jordi Corominas, and Ginés Viscor. Differences in cardiorespiratory responses in winter mountaineering according to the pathway snow conditions. High Alt Med Biol 20:000-000, 2019.-Locomotion during ascent requires higher energy consumption than on flat terrain. Locomotion efficiency decreases in snowy terrain, w...
Article
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Background The consumption of olive oil is associated with a diminished risk of cardiovascular disorders and mortality, but the impact of olive oil supplementation on endurance performance is still unclear. Since the beneficial effects of olive oil are observed at a systemic level, its effectiveness may not be precisely measured through the commonl...
Article
Background The influence of nutrition on breast cancer prognosis is still inconclusive and therefore dietary interventions incorporating dietary biomarkers are needed to confirm compliance with dietary goals and clarify biological mechanisms. The present study assessed whether a lifestyle intervention in breast cancer survivors could affect dietary...
Article
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Multiple sclerosis (MS) is a chronic neurological disease which affects young adults at a time of maximum personal, professional and social growth. Recent guidelines on physical activity have established that exercise is an essential component of the clinical management of people with MS with mild or moderate degree of disability. The main purpose...
Article
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In recent years, the altitude acclimatization responses elicited by short-term intermittent exposure to hypoxia have been subject to renewed attention. The main goal of short-term intermittent hypobaric hypoxia exposure programs was originally to improve the aerobic capacity of athletes or to accelerate the altitude acclimatization response in alpi...
Article
Adiposity and physical activity are modifiable factors that could be important determinants of breast cancer (BC) prognosis through their effects on endogenous reproductive hormones, chronic inflammation and metabolic changes. Therefore, it is necessary to evaluate whether offering lifestyle interventions to BC survivors could affect the levels of...
Article
Epidemiologic studies suggest that patients with breast cancer who gain weight after diagnosis have a higher risk of recurrence and death. Regular physical exercise can help minimize post-diagnosis weight gain. The objective of the study was to assess the effectiveness of a physical test for individualizing the workloads used during a fitness progr...
Article
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OBJETIVE: Our purpose was to study the effects of aerobic, resistance, and mixed (aerobic and resistance) training programs on blood pressure, both at rest and during submaximal exercise in healthy people. METHODS: We randomized 39 physically active, healthy participants into aerobic, resistance, and mixed (aerobic and resistance) exercise groups,...
Article
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The popularity of winter sports is leading to an increase in the number of subjects exposed to environmental pathologies such as frostbite. This is the reason why the patient's profile is changing from the classical descriptions of adults with preexisting conditions, basically those with cognitive impairment that prevented them from a proper protec...
Article
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Increases in cardiorespiratory coordination (CRC) after training with no differences in performance and physiological variables have recently been reported using a principal component analysis approach. However, no research has yet evaluated the short-term effects of exercise on CRC. The aim of this study was to delineate the behavior of CRC under...
Article
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Background Patients undergoing conventional hemodialysis (C-HD) present a greater immuno-inflammatory state probably related to uremia, sympathetic nervous system (SNS) activation and /or membrane bioincompatibility, which could improve with a technique-switching to online hemodiafiltration (OL-HD). The antigen-independent pathway activation of thi...
Data
Base data collection from clinical and experimental parameters. (XLS)
Article
The increase in pulmonary arterial pressure (PAP) due to hypoxic pulmonary vasoconstriction (HPV) could be a limiting factor for physical performance during hypoxic exposure. Sildenafil has been shown to reduce PAP in situations of moderate or severe hypoxia, and consequently its role as an ergogenic aid and even a possible doping substance must be...
Article
Background: Physical exercise can be part of treatment in patients with chronic fatigue syndrome (CFS), where the aim would be to improve strength and endurance through increasing physical exercise (intensity and time) without aggravating symptomatology. The present study examines the effectiveness of a reconditioning programme (focusing on streng...
Conference Paper
BACKGROUND: To determine the clinical risk factors predictive of the 5-year mortality in patients with low cardiac output syndrome (LCOS) after cardiac surgery. In addition, to assess the influence of inflammation and myocardial dysfunction severity, as measured by C-reactive protein (CRP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) co...
Article
Full-text available
Patients suffering from liver cirrhosis (LC) frequently require non-hepatic abdominal surgery, even before liver transplantation. LC is an important risk factor itself for surgery, due to the higher than average associated morbidity and mortality. This high surgical risk occurs because of the pathophysiology of liver disease itself and to the prese...
Article
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Our purpose was to study the effects of different training modalities and detraining on cardiorespiratory coordination (CRC). Thirty-two young males were randomly assigned to four training groups: aerobic (AT), resistance (RT), aerobic plus resistance (AT + RT), and control (C). They were assessed before training, after training (6 weeks) and after...
Article
Full-text available
Sildenafil has proven to efficiently reduce the increase in pulmonary artery pressure provoked by hypoxic pulmonary vasoconstriction. However, its role as a possible factor in increasing exercise performance under hypoxic conditions remains to be demonstrated. The use of sildenafil has increased among mountaineers, not as a high altitude pulmonary...
Article
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The possible effects of blue light during acute hypoxia and the circadian rhythm on several physiological and cognitive parameters were studied. Fifty-seven volunteers were randomly assigned to 2 groups: nocturnal (2200-0230 hours) or diurnal (0900-1330 hours) and exposed to acute hypoxia (4000 m simulated altitude) in a hypobaric chamber. The part...
Conference Paper
NTRODUCTION: People with intellectual disability (ID) have reduced balance ability, coordination and strength compared to people without ID. Motor impairments in people with ID are common, as ID affects cognitive and motor function. It is unknown if a Dance Movement Therapy Program (DMTP) can improve these variables. PURPOSE: To compare coordinati...
Conference Paper
INTRODUCTION: Adults with intellectual disability (AID) and seniors with intellectual disability (SID) have reduced cardiorespiratory fitness (CRF) and present low rates of physical activity (PA) levels and daily energy expenditure (DEE). It is unknown if CRF levels, PA levels and DEE are different between AID and SID with mild to moderate ID. PUR...
Article
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Liver cirrhosis has evolved an important risk factor for cardiac surgery due to the higher morbidity and mortality that these patients may suffer compared with general cardiac surgery population. The presence of contributing factors for a poor outcome, such as coagulopathy, a poor nutritional status, an adaptive immune dysfunction, a degree of cirr...
Article
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This study assessed changes in quality of life (QoL) and cardiorespiratory fitness (CRF) during a diet and physical activity (PA) intervention in breast cancer (BC) survivors and investigated the relation between these changes. The intervention of this single-arm pre-post study involved supervised, 1-hour weekly, diet sessions and 75-minute bi-week...
Article
Although hyperlactatemia is common after cardiac surgery, its value as a prognostic marker is unclear. The aim of the present study was to determine whether postoperative serial arterial lactate (AL) measurements after cardiac surgery could predict outcome. Prospective, observational study. Surgical intensive care unit in a tertiary-level universit...
Article
Full-text available
To determine the clinical risk factors predictive of the 5--year mortality in patients with low cardiac output syndrome (LCOS) after cardiac surgery. In addition, to assess the influence of inflammation and myocardial dysfunction severity, as measured by C--reactive protein (CRP) and N--terminal pro--brain natriuretic peptide (NT--proBNP) concentra...
Article
Full-text available
Obesity influences risk stratification in cardiac surgery in everyday practice. However, some studies have reported better outcomes in patients with a high body mass index (BMI): this is known as the obesity paradox. The aim of this study was to quantify the effect of diverse degrees of high BMI on clinical outcomes after cardiac surgery, and to as...
Article
Physical exercise can be part of treatment in patients with chronic fatigue syndrome (CFS), where the aim would be to improve strength and endurance through increasing physical exercise (intensity and time) without aggravating symptomatology. The present study examines the effectiveness of a reconditioning programme (focusing on strength, endurance...
Chapter
Magnesium (Mg) is an important intracellular ion with electrophysiological properties. It is essential for optimal metabolic cell function. Serum Mg is a poor predictor of body stores, as less than 1 % of total body Mg is found in serum. Ionized Mg assessment, the active portion of Mg, may be a more useful indicator than total serum Mg assessment....
Article
Full-text available
Circulating progenitor cells (CPC) are bone marrow-derived cells that are mobilized into the circulation. While exercise is a powerful mediator of hematopoiesis, CPC levels increase, and reports of their activation after different types of exercise are contradictory. Moreover, few studies have compared the possible effects of different training pro...
Article
Background: Circulating progenitor cells (CPC) treatments may have great potential for the recovery of neurons and brain function. Objective: To increase and maintain CPC with a program of exercise, muscle electro-stimulation (ME) and/or intermittent-hypobaric-hypoxia (IHH), and also to study the possible improvement in physical or psychological...