Carminna Ottone

Carminna Ottone
Pontifical Catholic University of Valparaíso | PUCV · School of Biochemical Engineering

PhD in Materials Science and Technology

About

45
Publications
7,628
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672
Citations
Introduction
Carminna Ottone currently works at the School of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso. Carminna does research in Bioengineering, Materials Science and Materials Physics. Their current project is 'Electrochemical regeneration of NAD(H) cofactors'.
Additional affiliations
January 2015 - March 2015
Evonik Industries
Position
  • External Engineer
February 2015 - February 2015
Evonik Industries
Position
  • External Engineer
January 2012 - December 2014
Istituto Italiano di Tecnologia
Position
  • PhD Student

Publications

Publications (45)
Article
Full-text available
Chemical amination of the enzyme was demonstrated to favor immobilization onto polydopamine (PDA)-coated magnetic nanoparticles (MNPs) for the first time, to the best of the author’s knowledge. MNPs prepared via hydrothermal synthesis were coated with PDA for the immobilization of naringinase. X-ray diffraction, transmission electron microscopy, X-...
Article
Full-text available
Cancer is the second leading cause of death worldwide, with a dramatic impact due to the acquired resistance of cancers to used chemotherapeutic drugs and treatments. The enzyme lactate dehydrogenase (LDH-A) is responsible for cancer cell proliferation. Recently the development of selective LDH-A inhibitors as drugs for cancer treatment has been re...
Article
Bioelectrochemistry has gained importance in recent years for some of its applications on waste valorization, such as wastewater treatment and carbon dioxide conversion, among others. The aim of this review is to provide an updated overview of the applications of bioelectrochemical systems (BESs) for waste valorization in the industry, identifying...
Article
Full-text available
Ascorbyl palmitate, an ascorbic acid ester, is an important amphipathic antioxidant that has several applications in foods, pharmaceuticals, and cosmetics. The enzymatic synthesis of ascorbyl palmitate is very attractive, but few efforts have been made to address its process scale-up and implementation. This study aimed at evaluating the enzymatic...
Chapter
Enzyme immobilization has been extensively reviewed in the literature, so the focus in this chapter is on novel promising strategies, highlighting opportunities and challenges. New opportunities for enzyme immobilization arise regarding the development of novel strategies and new support materials, and multienzymatic and bioelectrochemical processe...
Article
Full-text available
In this work, the co-immobilization of formate dehydrogenase (FDH) and glycerol dehydrogenase (GlyDH) enzymes is proposed to reduce CO2 into formic acid, an important chemical intermediate. The reduction of carbon dioxide is carried out by FDH to obtain formic acid, simultaneously, the GlyDH regenerated the nicotinamide cofactor in the reduced form...
Article
Full-text available
This study presents the immobilization with aldehyde groups (glyoxyl carbon felt) of alcohol dehydrogenase (ADH) and formate dehydrogenase (FDH) on carbon‐felt‐based electrodes. The compatibility of the immobilization method with the electrochemical application was studied with the ADH bioelectrode. The electrochemical regeneration process of nicot...
Article
Full-text available
Purpose This work studies the immobilization of two enzymes, the alcohol dehydrogenase (ADH) and the aldehyde dehydrogenase (AldDH) both from Saccharomyces cerevisiae , which could be used to produce high value-added molecules from carboxylic acids embedded in anaerobic digestate. Methods In particular, three mesoporous siliceous materials, with d...
Chapter
Enzymes are outstanding biocatalysts for catalyzing reactions under mild conditions, with versatile substrate specificity and high product selectivity. Despite these desirable properties, the industrial application of soluble enzymes is hindered by their low operational stability and efficiency of use leading to a high incidence of enzyme’s operati...
Article
The enzymatic production of lactofructose syrup from lactose coming from surplus whey represents a sound example of circular economy. The production process requires the sequential action of two enzymes, namely β-galactosidase and glucose (xylose) isomerase, which can act independently in different reactors or in a one-pot system. The latter is an...
Article
This work reports the study of ZnO-based anodes for the photoelectrochemical regeneration of the oxidized form of nicotinamide adenine dinucleotide (NAD+). The latter is the most important coenzyme for dehydrogenases. However, the high costs of NAD+ limit the use of such enzymes at the industrial level. The influence of the ZnO morphologies (flower...
Article
This work studied the influence of the pore size and morphology of the mesoporous silica as support for formate dehydrogenase (FDH), the first enzyme of a multi-enzymatic cascade system to produce methanol, which catalyzes the reduction of carbon dioxide to formic acid. Specifically, a set of mesoporous silicas was modified with glyoxyl groups to i...
Chapter
Enzymes are biological catalysts capable of recognizing a substrate and catalyze reactions of hydrolysis and synthesis. The most significant property of enzymes is their high specificity toward their substrates since they are able to recognize and act upon a molecule from a pool of similar compounds. Enzymes are labile catalysts at certain operativ...
Article
Photolyases are enzymes that repair DNA damage caused by solar radiation. Due to their photorepair potential, photolyases added in topical creams and used in medical treatments has allowed to reverse skin damage and prevent the development of different diseases, including actinic keratosis, premature photoaging and cancer. For this reason, research...
Article
The enzymatic strategy for methanol production starting from CO2 involves the use of three enzymes in series. The first enzyme of the series, which reduces CO2 to formic acid, is formate dehydrogenase (FDH). A problem with using free enzymes is their low stability. To overcome this limitation, the covalent immobilization on porous supports has been...
Article
Wastewater production is rising all over the world and one of the most difficult problems is the disposal of sewage sludge (SS). It is known that SS contains certain quantities of added-value compounds, such as humic acids (HA) which in turn have beneficial effects on soil quality and plant growth. On the other hand, SS can retain many pollutants,...
Article
Glycosidases are enzymes involved in the cascade reactions leading to the release of aromatic compounds in white wines. However, the use of commercial soluble glycosidases is facing difficulties due to their fast inactivation, poor reaction control, low efficiency of enzyme use, and the presence of catalyst residues in the product. Co-immobilizatio...
Article
Full-text available
Enzymes are powerful catalysts already being used in a large number of industrial processes. Impressive advantages in enzyme catalysts improvement have occurred in recent years aiming to improve their performance under harsh operation conditions far away from those of their cellular habitat. Production levels of the winemaking industry have experie...
Article
Full-text available
Ascorbyl palmitate is a fatty acid ester endowed with antioxidant properties, used as a food additive and cosmetic ingredient, which is presently produced by chemical synthesis. Ascorbyl palmitate was synthesized from ascorbic acid and palmitic acid with a Pseudomonas stutzeri lipase immobilized on octyl silica, and also with the commercial immobil...
Chapter
An overview of the different sacrificial oxidants used in literature is reported, paying particular attention to the “sacrificial pair” \(\text{Ru}(\text{bpy})_{3}^{2 + } \text{/S}_{2} \text{O}_{8}^{2 - }\), a photosystem made of a Ru-dye (Tris(bipyridine)ruthenium(II) dichloride, working as “antenna” for visible light) and a final electron accepto...
Chapter
This chapter focuses on some aspects concerning the realization of an actually sustainable H2 production, and especially the need for earth abundant, environmental friendly, solar driven heterogeneous catalysis for the Water Oxidation reaction: the catalyst shall be thermodynamically and mechanically stable to allow cyclic long-term operations. The...
Chapter
In actual water splitting devices, the WOC will be deposited on an anode surface. Therefore, whatever the results obtained with WOC particles suspended in stirrer tank reactors, it becomes necessary to study WOC performances by means of electrochemical experimental setups. The WOCs deposition on an anode will depend on their physico-chemical nature...
Chapter
This chapter will cover the most important aspects concerning the water splitting reaction by providing an overall description of the main solutions, as reported in the literature, addressing the improvement of the efficiency of solar driven hydrogen production. The natural water splitting system will be considered as a starting point, in order to...
Chapter
This chapter will address the main issues related to the scaling up of a WS process. Currently, only few examples of pilot-scale water splitting (WS) devices are available in literature: low efficiencies and high costs are the main aspects that limit the use of this technology at industrial level, since results obtained at lab-scale are difficult t...
Chapter
In the current chapter, the use of a bubbling reactor for investigating the activity of different manganese oxides (i.e. Mn2O3, Mn3O4 and MnO2) is described. The most important aspects of water oxidation reaction considered are the role of the catalyst specific surface area (SSA), and the effect of the irradiance on the \({\text{Ru}} ({\text{bpy}})...
Book
This book offers comprehensive information on the main techniques for measuring water-oxidation-catalyst (WOC) performance, with a particular focus on the combined use of sacrificial oxidants and dyes within closed-batch reactors. It provides an overview of the latest advances in the synthesis of more efficient WOCs, followed by an analysis of the...
Article
Full-text available
This work reports on the oxidation of long-chain aliphatic alcohols catalyzed by a stabilized alcohol dehydrogenase from S. cerevisiae (yeast alcohol dehydrogenase (YADH)). In particular, the oxidation of the fatty alcohol tetracosanol (C24H50O) to yield lignoceric acid (C23H47COOH) was studied. The immobilization of YADH onto glyoxyl agarose suppo...
Article
Full-text available
Correction for ‘Core-substituted naphthalenediimides anchored on BiVO4 for visible light-driven water splitting’ by Simelys Hernández et al., Green Chem., 2017, 19, 2448–2462.
Article
In this work, a novel catalytic system for the sunlight-driven water splitting, which exploits the photocatalytic ability of BiVO4 coupled to a new kind of noble-metal-free organic dye molecules, is proposed. Hence, mono- and di-substituted naphtalenediimides (NDIs), were designed to have different functional groups that provide to them both tunabl...
Article
The Ru(bpy)3]²⁺/persulfate photosystem is the most common dye/sacrificial reagent pair used to study the catalyzed water oxidation half-reaction. Recently, we developed a bubbling reactor along with its modelling, and we used it with the aforementioned photosystem to measure the actual rate of reaction (RO2) over time. In the present work, the same...
Article
Full-text available
Manganese oxides (MnOx), being active, inexpensive and low-toxicity materials, are considered promising water oxidation catalysts (WOCs). This work reports the preparation and the physico-chemical and electrochemical characterization of spin-coated (SC) films of commercial Mn2O3, Mn3O4 and MnO2 powders. Spin coating consists of few preparation step...
Article
Highly oriented zinc oxide (ZnO) nanotubes were synthesized in a porous polycarbonate (PC) matrix, leading to a highly flexible ZnO–PC composite able to work as efficient energy nanogenerator. The crystalline direction of the ZnO c-axis is obtained parallel to the membrane surface, thus advantageous for the exploitation of composite under bending s...
Article
Commercial Mn2O3, Mn3O4 and MnO2 and the same after thermal or ball-milling treatments have been examined as catalysts for the photocatalytic water oxidation reaction, using [Ru(bpy)3]2+ as photosensitizer and S2O82− as sacrificial electron acceptor. Tests were performed in a bubbling reactor, allowing the calculation of the actual rate of O2 evolu...
Article
Highly mesoporous ZnO and γ-Al2O3 nanowires (NWs) are both synthesized by a hydrothermal method using commercially available porous anodic aluminium oxide (AAO) as template. AAO membrane acts as template for ZnO NWs and both as template and precursor for γ-Al2O3 NWs. The formation of intermediate phases of porous Zn6Al2(OH)16CO3 and boehmite (γ-AlO...
Article
Full-text available
The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoot...
Article
Full-text available
Titania nanotubes (TiO2 NTs) of 5 mu m in length and 100 nm in the external diameter are easily formed by anodic oxidation. They are used as hollow substrates to deposit different ZnO nanostructures, such as nanoparticles and nanowires by employing two different techniques, electrodeposition and hydrothermal growth, respectively. In this way highly...
Article
Full-text available
Titania nanotubes (TiO2 NTs) of 5 μm in length and 100 nm in the external diameter are easily formed by anodic oxidation. They are used as hollow substrates to deposit different ZnO nanostructures, such as nanoparticles and nanowires by employing two different techniques, electrodeposition and hydrothermal growth, respectively. In this way highly n...
Article
Full-text available
ZnO nanowires were synthesized by combining the template-assisted method with three different ZnO growth approaches, i.e. sol–gel, aqueous chemical growth, and electrodeposition. We obtained nanostructures of 200, 50, and even 5 nm diameter in porous alumina and ordered mesoporous silica membranes, showing effective filling of the template channels...
Chapter
In the present chapter we aim to overview the synthesis techniques and growth mechanism of zinc oxide (ZnO) nanowires and their related properties. In particular, here we review both wet and dry synthesis techniques reported in the literature, such as hydrothermal and sol-gel routes, template-assisted growth, electrodeposition process, chemical vap...

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