Carlos Ugrinowitsch

Carlos Ugrinowitsch
University of São Paulo | USP · Department of Sport (EEFESP)

Ph.D. in Exercise Science

About

291
Publications
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7,995
Citations
Additional affiliations
August 1993 - present
University of São Paulo
Position
  • Professor (Associate)

Publications

Publications (291)
Article
A decrease in brain volume (i.e., brain atrophy) is a marker of cognitive health in older adults. Insufficient weekly accumulation of moderate and vigorous physical activity (MVPA) has been associated with lower brain volume. As this association has been established for a small number of brain areas and structures and atrophy rates seem to be nonun...
Article
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Losses in skeletal muscle mass, strength, and metabolic function are harmful in the pathophysiology of serious diseases, including breast cancer. Physical exercise training is an effective non-pharmacological strategy to improve health and quality of life in patients with breast cancer, mainly through positive effects on skeletal muscle mass, stren...
Article
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We aimed to investigate whether muscle fiber cross‐sectional area (fCSA) and associated molecular processes could be differently affected at the group and individual level by manipulating resistance training (RT) variables. Twenty resistance‐trained subjects had each leg randomly allocated to either a standard RT (RT‐CON: without specific variables...
Article
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Background Evidence has demonstrated that endurance training (ET) reduces the motor signs of Parkinson’s disease (PD). However, there has not been a comprehensive meta-analysis of studies to date. Objective The aim of this study was to compare the effect of ET versus nonactive and active control conditions on motor signs as assessed by either the...
Article
Background: Skeletal muscle adaptations are affected by resistance training (RT)-induced acute and chronic transcriptional responses. An under-explored gene target involved in mechanotransduction is the expression of the G protein-coupled receptor 56 (GPR56). However, studies investigating the acute and chronic effects of RT manipulations on GPR56...
Article
Purpose Biodex Balance System (BBS) is a low-cost platform used to assess balance in different populations. However, no study has used this tool to evaluate the risk of falls related to balance changes in non-faller individuals with Parkinson Disease (PD). Objective The aim of this study was to determine the changes in the balance in non-faller in...
Article
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Context: Low-load resistance training (LL) and neuromuscular electrostimulation (NES), both combined with blood flow restriction (BFR), emerge as effective strategies to maintain or increase muscle mass. It is well established that LL-BFR promotes similar increases in muscle cross-sectional area (CSA) and lower rating of perceived exertion (RPE) a...
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Background Most cancer patients, under active treatment or not, are sedentary, despite increasing scientific and clinical understanding of the benefits of exercise and physical activity, such as improving quality of life, limiting disease symptoms, decreasing cancer recurrence, and increasing overall survival. Studies have shown that both supervise...
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We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers. Resistance-trained men ( n = 20; 26 ± 3 years old) trained for 8 weeks where a randomized leg performed either a standard (CON) or variable RT pro...
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O objetivo deste estudo foi propor um modelo de avaliação qualitativa de livros e capítulos de livros com base na percepção da comunidade de docentes da Área 21 da Capes sobre o prestígio das editoras. Noventa orientadores de programas de pós-graduação das diferentes regiões do país responderam a um questionário de avaliação da percepção do prestíg...
Article
Using a within-subject design we compared the individual responses between drop-set (DS) vs. traditional resistance training (TRAD) (n=16) and crescent pyramid (CP) vs. TRAD (n=15). Muscle cross-sectional area (CSA), leg press and leg extension 1 repetition maximum (1-RM) were assessed pre and post training. At group level, CSA increased from pre t...
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There is emerging evidence that decreased muscle mass and cardiorespiratory fitness (CRF) are associated with increased risk of cancer-related mortality. This paper aimed to present recommendations to prescribe effective and safe exercise protocols to minimize losses, maintain or even improve muscle mass, strength, and CRF of the cancer patients wh...
Article
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O objetivo deste estudo foi verificar dentre os sintomas motores, sintomas não motores e o medo de cair quais seriam os principais preditores de qualidade de vida em indivíduos nos estágios 2 e 3 da doença de Parkinson (DP). Trinta e nove indivíduos com DP (64,1±9,1 anos, 10,3±4,7 duração da DP) avaliados no estado on da medicação participaram do e...
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Previous research has suggested that concurrent training (CT) may attenuate resistance training (RT)-induced gains in muscle strength and mass, i.e.‚ the interference effect. In 2000, a seminal theoretical model indicated that the interference effect should occur when high-intensity interval training (HIIT) (repeated bouts at 95–100% of the aerobic...
Article
Teixeira, EL, Ugrinowitsch, C, de Salles Painelli, V, Silva-Batista, C, Aihara, AY, Cardoso, FN, Roschel, H, and Tricoli, V. Blood flow restriction does not promote additional effects on muscle adaptations when combined with high-load resistance training regardless of blood flow restriction protocol. J Strength Cond Res 35(5): 1194-1200, 2021-The a...
Article
Introduction: Exercise-induced microRNAs (miRNAs) expression has been implicated in the regulation of skeletal muscle plasticity. However, the specificity and acute time course in miRNA expression following divergent exercise modes are unknown. In a randomized cross-over design, we compared the acute expression profile of eight skeletal muscle miR...
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Background Individuals with Parkinson's disease (PD) who report freezing of gait (FOG) have poorer sleep quality than those without FOG. Cognitive, anxiety, and mobility disability are components of the FOG phenotype, however, no study has investigated if poor sleep quality is associated with all three components that underlie FOG in PD. Research...
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This study compared the effects of FAST and SLOW eccentric repetition tempo in a single exercise volume-matched intervention on muscle thickness (MT) and strength in resistance-trained men. Using a within- subject design, 13 subjects had each leg randomly assigned to SLOW (1-0-3) or FAST (1-0-1) repetition tempo. Subjects un- derwent an 8-week stre...
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Age-related changes in presynaptic inhibition (PSI) have not been observed during gait initiation, which requires anticipatory postural adjustment (APA). As APA is centrally modulated and is impaired in older compared to young adults, here we aimed to study the presynaptic control and co-contraction levels in the ankle muscles during gait initiatio...
Article
Background: The ability to produce force is critical to several daily activities. Strategies to reduce delayed onsent muscle soreness (DOMS) and restore force-generating properties that occur in response to training and impair physical performance have been proposed. Acupuncture has been proposed to accelerate recovery and optimize muscle functioni...
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Background: Deficits in the cerebellar locomotor region (CLR) have been associated with loss of gait automaticity in individuals with freezing of gait in Parkinson's disease (freezers); however, exercise interventions that restore gait automaticity in freezers are lacking. We evaluated the effects of the adapted resistance training with instabilit...
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Previous research has demonstrated large amounts of inter-subject variability in downward (unweighting & braking) phase strategies in the countermovement jump (CMJ). The purpose of this study was to characterize downward phase strategies and associated temporal, kinematic and kinetic CMJ variables. One hundred and seventy-eight NBA (National Basket...
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Caffeine improves cycling time trial performance through enhanced motor output and muscle recruitment. However, it is unknown if caffeine further increases power output entropy. To investigate the effects of caffeine effects on cycling time trial performance and motor output entropy (MOEn), nine cyclists (VO2MAX of 55 ± 6.1 mL.kg.-1min⁻¹) performed...
Article
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While performing aerobic exercise during chemotherapy has been proven feasible and safe, the efficacy of aerobic training on cardiorespiratory fitness (CRF) in women with breast cancer undergoing chemotherapy has not yet been systematically assessed. Therefore, the objective of this work was to determine (a) the efficacy of aerobic training to impr...
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Aim: This study aimed to test the influence of functional improvements in volleyball skills performance. Methods: Twenty-eight amateur female volleyball players were assigned to Skill (S: n = 14, 19.5 ± 4.6 yrs; 169.7 ± 7.2 cm; 62.9 ± 12.7 kg) or Skill and Strength/Power (S+SP: n = 14; 18.6 ± 3.5 yrs; 169.7 ± 5.1 cm; 63.3 ± 9.2 kg). S+SP performed...
Article
Background Exercises with motor complexity induce neuroplasticity in individuals with Parkinson's disease (PD), but its effects on freezing of gait are unknown. The objective of this study was to verify if adapted resistance training with instability — exercises with motor complexity will be more effective than traditional motor rehabilitation — ex...
Article
Gomes, RL, Lixandrão, ME, Ugrinowitsch, C, Moreira, A, Tricoli, V, and Roschel, H. Session rating of perceived exertion as an efficient tool for individualized resistance training progression. J Strength Cond Res XX(X): 000-000, 2020-The present study aimed to investigate the effects of an individualized resistance training (RT) progression model b...
Article
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This study investigated the effects of 12-SET, 18-SET, and 24-SET lower-body weekly sets on muscle strength and mass accretion. Thirty-five resistance-trained individuals (one repetition maximum [1RM] squat: body mass ratio [1RM: BM] 5 2.09) were randomly divided into 12-SET: n 5 13, 18-SET: n 5 12, and 24-SET: n 5 10. Subjects underwent an 8-week...
Article
Key points: Individuals with freezing of gait (FoG) due to Parkinson's disease (PD) have small and long anticipatory postural adjustments (APA) associated with delayed step initiation. Individuals with FoG (freezers) may require functional reorganization of spinal mechanisms to perform APAs due to supraspinal dysfunction. As presynaptic inhibition...
Article
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Scarpelli, MC, Nóbrega, SR, Santanielo, N, Alvarez, IF, Otoboni, GB, Ugrinowitsch, C, and Libardi, CA. Muscle hypertrophy response is affected by previous resistance training volume in trained individuals. J Strength Cond Res XX(X): 000-000, 2020-The purpose of this study was to compare gains in muscle mass of trained individuals after a resistance...
Article
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Basketball has seen an increase in the number of players who perform multiple tactical roles. Therefore, the aim of the study was twofold: (i) to define a method to characterize basketball players as versatile or specialists, based on 13 game-related statistics; (ii) to evaluate versatile-specialist tendencies in a professional national league. A p...
Article
Purpose: Sleep is considered essential for muscle recovery, mainly due to its effect on hormone secretion. Total sleep deprivation or restriction is known to alter not only blood hormones but also cytokines that might be related to skeletal muscle recovery. This study aimed to evaluate whether total sleep deprivation after eccentric exercise-induc...
Article
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Background: Minimal detectable change (MDC) when assessing balance using the Biodex Balance System (BBS) in patients with Parkinson disease (PD) is currently unknown, limiting the interpretability of the scores. Objective: To determine the MDC on the Anterior/Posterior Stability Index (APSI), Medial/Lateral Stability Index (MLSI), and Overall St...
Article
BACKGROUND: Minimal detectable change (MDC) when assessing balance using the Biodex Balance System® (BBS) in patients with Parkinson Disease (PD) is currently unknown, limiting the interpretability of the scores. OBJECTIVE: To determine the MDC on the anterior/posterior stability index (APSI), medial/lateral stability index (MLSI), and overall st...
Article
The manipulation of resistance training (RT) variables is used among athletes, recreational exercisers and compromised populations (e.g., elderly) attempting to potentiate muscle hypertrophy. However, it is unknown whether an individual's inherent predisposition dictates the RT-induced muscle hypertrophic response. Twenty resistance-trained young (...
Article
To optimize/maximize increases on muscle strength and mass in well resistance-trained individuals, the use of resistancetraining (RT) systems have been widely recommended by powerlifters, bodybuilders and coaches. These systems may be characterized as advanced techniques that manipulate specific RT variables emphasizing physiologic mechanisms. Howe...
Article
This study had two objectives: 1) to compare the effects of 3 wk of resistance training (RT) and resistance training with instability (RTI) on evoked reflex responses at rest and during maximal voluntary isometric contraction (MVIC) of individuals with Parkinson’s disease (PD) and 2) to determine the effectiveness of RT and RTI in moving values of...
Article
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The metabolic stress induced by blood flow restriction (BFR) during resistance training (RT) might maximize muscle growth. However, it is currently unknown whether metabolic stress are associated with muscle hypertrophy after RT protocols with high- or low load. Therefore, the aim of the study was to compare the effect of high load RT (HL-RT), high...
Article
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Significant muscle wasting is generally experienced by ill and bed rest patients and older people. Muscle wasting leads to significant decrements in muscle strength, cardiorespiratory, and functional capacity, which increase mortality rates. As a consequence, different interventions have been tested to minimize muscle wasting. In this regard, blood...
Article
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The aims of the present study were to systematize a set of concatenated space creation dynamics in basketball and to use it to analyze teams’ offenses. Space creation dynamics concatenation concept was investigated and classes were defined. Modeling resulted in independent and dependent concatenations’ classes. Agreement was at least 0.85 for all s...
Article
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The aim of the present study was to investigate if resistance training (RT), performed with individualized recovery between sessions (RT-IND), promotes greater gains in strength and muscle mass and reduces the variability on adaptations compared to RT with fixed recovery intervals (RT-FIX). Twenty young men (age 21.9 ± 3.3 years) were randomized in...
Article
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This study investigated the effects of advanced training techniques (ATT) on muscular responses and if performing a second training session would negatively affect the training stimulus. Eleven strength-trained males performed a traditional strength training session (TST) and four different ATT: pre-exhaustion A (PE-A), pre-exhaustion B (PE-B), for...
Article
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Background Gene expression is an important process underpinning the acute and chronic adaptive response to resistance exercise (RE) training. PurposeTo investigate the effect of training status on vastus lateralis muscle global transcriptome at rest and following acute RE. Methods Muscle biopsies of nine young men (age: 26(2) years; body mass: 69(9...
Presentation
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Para melhorar os aspectos estratégicos/táticos de equipes de basquetebol, técnicos têm comumente incluído em seus programas de treinamento, situações simuladas de jogo. Essas simulações se assemelham às situações de jogo e são utilizadas para aprendizagem de jogadas nas quais os atletas objetivam quebrar o equilíbrio defensivo. Nesse sentido, uma h...
Article
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Background Patients with major depression disorder presents increased rates of cognitive decline, reduced hippocampal volume, poor sleep quality, hypertension, obesity, suicidal ideation and behavior, and decreased functionality. Although continuous aerobic exercise (CAE) improves some of the aforementioned symptoms, comorbidities, and conditions,...
Article
Damas, F, Barcelos, C, Nóbrega, SR, Ugrinowitsch, C, Lixandrão, ME, Santos, LMEd, Conceição, MS, Vechin, FC, and Libardi, CA. Individual muscle hypertrophy and strength responses to high vs. low resistance training frequencies. J Strength Cond Res XX(X): 000-000, 2018-The aim of this short communication was to compare the individual muscle mass and...
Article
The aim of the present study was to investigate the acute effect of the aerobic exercise volume on maximum strength and strength-endurance performance; and possible causes of strength decrements (i.e. central and peripheral fatigue). Twenty-one moderately trained men were submitted to a maximal incremental test to determine anaerobic threshold (AnT...
Article
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Caffeine (CAF) is an ergogenic aid used to improve exercise performance. Independent studies have suggested that caffeine may have the ability to increase corticospinal excitability, thereby decreasing the motor cortex activation required to generate a similar motor output. However, CAF has also been suggested to induce a prefrontal cortex (PFC) de...
Article
Context: Given the comparable muscle hypertrophy constantly observed between blood-flow restriction exercise (BFR-RE) and conventional resistance exercise, understanding their particular rating of perceived exertion (RPE) and pain may help to better prescribe exercise at a low-discomfort level, thus increasing its feasibility. Design: Randomized...
Article
We aimed to investigate the mechanisms underlying muscle growth after 12 weeks of RT-BFR and HRT in older individuals. Participants were allocated into the groups HRT, RT-BFR and control (CG). High-throughput transcriptome sequencing was performed by the Illumina HiSeq2500 platform. HRT and RT-BFR presented similar increases in quadriceps femoris C...
Conference Paper
Full-text available
INTRODUCTION: The carbohydrate (CHO) mouth rinse has been accepted as an ergogenic aid to improve endurance performance in different exercise modes. The likely mechanism underpinning the CHO mouth rinse effects on endurance performance is a greater reward system-cerebral activation that attenuates neuromuscular fatigue, thus ameliorating muscle act...
Article
The aim of this study was to investigate the effects of an acute bout of eccentric actions, performed at fast velocity (210°.s⁻¹) and at slow velocity (20°.s⁻¹), on the gene expression of regulatory components of the myostatin (MSTN) signalling pathway. Participants performed an acute bout of eccentric actions at either a slow or a fast velocity. M...
Article
The aim of the study was to compare the effect of resistance training (RT) frequencies of five times (RT5), thrice- (RT3) or twice- (RT2) weekly in muscle strength and hypertrophy in young men. Were used a within-subjects design in which 20 participants had one leg randomly assigned to RT5 and the other to RT3 or to RT2. 1 RM and muscle cross-secti...
Presentation
Full-text available
Verificar se o TF realizado com intervalo de recuperação entre sessões de forma individualizada (TF-IND) promove maior aumento na força e hipertrofia muscular que o TF realizado com intervalos de fixos recuperação (TF-FIX).
Article
Background: Patients with Parkinson disease (PD) present cardiovascular autonomic dysfunction which impairs blood pressure control. However, cardiovascular responses during resistance exercise are unknown in these patients. Objective: Investigate the cardiovascular responses during resistance exercise performed with different muscle masses, in p...
Article
Full-text available
The present study investigated the effects of different intensities of resistance training (RT) on elbow flexion and leg press one-repetition maximum (1RM) and muscle cross-sectional area (CSA). Thirty men volunteered to participate in an RT programme, performed twice a week for 12 weeks. The study employed a within-subject design, in which one leg...
Article
Full-text available
We investigated if a carbohydrate (CHO) mouth rinse may attenuate global fatigue and improve 4-km cycling time trial (TT 4km) performance. After a preliminary session, cyclists (n = 9) performed a TT 4km after a CHO or placebo (PLA) mouth rinse. Mean power output, time, and ratings of perceived exertion (RPE) were recorded throughout the TT 4km. Tw...