Carlos Toro-Huamanchumo

Carlos Toro-Huamanchumo
Universidad San Ignacio de Loyola · Unidad para la Generación y Síntesis de Evidencias en Salud

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129
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Publications

Publications (129)
Article
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Background A predictive scoring system used in patients with acute respiratory distress syndrome (ARDS) known as Age, PaO2/FiO2, Plateau Pressure Score (APPS) has been externally validated to predict mortality in Asian and Caucasian populations. Its performance in Latin American and COVID-19 patients still needs to be done. Objective To assess the...
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Background Sleeve gastrectomy has gained prominence in obesity treatment, yet it is not without complications, such as the development of anemia in the medium term. Given the high prevalence of Helicobacter pylori infection in Peru, it is imperative to explore its potential association with this postoperative complication. Objective To evaluate th...
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Objective To evaluate the association between GGT/HDL-C ratio and resolution of MetS in adults after sleeve gastrectomy (SG). Methods We conducted a retrospective cohort study using secondary data from a Peruvian bariatric center. The study population consisted of adults aged 18 and above who underwent laparoscopic SG and were diagnosed with MetS...
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Background The prevalence of hypertension in Peru has increased over the years. Approximately one third of the Peruvian population lives at high altitudes. This population presents particular physiological, genetic and environmental characteristics that could be related to the prevalence of hypertension and its subtypes. Objective To assess the as...
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Background According to the World Health Organization, tuberculosis (TB) ranks among the top 10 causes of death worldwide. The significance of TB during pregnancy lies in its symptoms, which can be mistaken for physiological changes associated with pregnancy. This confusion can lead to maternal-perinatal complications. Objective To evaluate the as...
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Background Intimate partner violence (IPV) in Peru represents a significant public health challenge. IPV can influence women’s reproductive and social behaviors, undermining fertility control, and exacerbating unintended pregnancies. Our objective was to assess the association between IPV and pregnancy intention among Peruvian women of reproductive...
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Background: Health behaviors, such as inadequate fruit and vegetable intake, alcohol abuse, and smoking, can impact mental health. This study aimed to assess the association between these behaviors and depressive symptoms in Peruvian adults. Methods: We conducted a secondary data analysis of the 2019 Peruvian Demographic Health Survey (ENDES). The...
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Objective We aimed to evaluate the determinants of non-institutional delivery among women of childbearing age in Peru. Methods We conducted a secondary analysis of data from the Peru 2019 Demographic and Family Health Survey (ENDES). This multi-stage survey sampling is representative at the urban-rural, regional, and national levels. The outcome v...
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Background Sexually transmitted infections (STIs) are a serious public health problem worldwide, especially among reproductive-age women. The early sexual onset of sexual intercourse (EOSI) has been suggested as a risk factor, although there is no data at the national level. Objective To evaluate the association between EOSI and STIs in Peruvian w...
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Background Cardiovascular diseases are responsible for the majority of deaths resulting from non-alcoholic fatty liver disease (NAFLD). NAFLD is associated with hypertension and this is a key predictor of severe liver outcomes and an indicator of nonspecific portal fibrosis. Aim To assess the association between hypertension and NAFLD severity. M...
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Background Among the most recent methods to diagnose liver fibrosis is 2D shear wave elastography (2D-SWE). However, the evidence in the Latin population is limited, and there is no consensus on the cutoff points for each stage of fibrosis. Aim To evaluate the diagnostic performance of 2D-SWE for liver fibrosis in adults with obesity who underwent...
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Introduction: Early onset neonatal sepsis (EONS), particularly in preterm sepsis, is a potentially fatal issue. Evaluation of mean platelet volume (MPV) as an EONS predictor was the goal. Methods: Four databases were used to conduct a systematic evaluation of cohort and case-control studies. Up till the end of October 2022, 137 articles were fou...
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Background: Our study aimed to describe the variation in the frequency of correct mask use among pedestrians in the first and second waves of the COVID-19 pandemic in high-flow indoor public spaces from different geographic and social settings in Peru. Methods: We carried out a cross-sectional exploratory study among pedestrians in Lima (the capita...
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Introducción: El objetivo de este estudio fue evaluar la eficacia de los programas de tratamiento para la ciberadicción en niños y adolescentes. Material y Métodos: Se realizó la búsqueda en cinco bases de datos. Se seleccionaron ensayos controlados aleatorizados (ECA) o estudios de cohorte que evaluaron la eficacia de programas de tratamiento para...
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Se realizó una evaluación de tecnología sanitaria (ETS) con el objetivo de analizar críticamente la evidencia sobre la eficacia y seguridad de la corrección quirúrgica de las deformidades de la columna vertebral con el uso de la técnica coplanar, en comparación con la técnica de derotación convencional, en pacientes niños, jóvenes y adultos. Se lle...
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Introduction Recurrent positivity in a patient with COVID-19 may be due to various reasons, not necessarily reinfection. There is concern about the occurrence frequency of reinfection. Methods Five databases and a preprint/preprint repository were searched. All case reports, case series, and observational studies were included. Bias was assessed...
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Background: Metabolic Syndrome (MetS) is a clinical entity that has been linked to several non-communicable diseases. There are various consensuses to determine its presence, such as the IDF, ALAD, Harmonized, AHA/NHLBI, NCEP-ATP III or AACE criteria. However, there is currently no standardization to properly identify it. Objective: To assess th...
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Background Oropouche fever is an infectious disease caused by the Oropouche virus (OROV). The diagnosis and prediction of the clinical picture continue to be a great challenge for clinicians who manage patients with acute febrile syndrome. Several symptoms have been associated with OROV virus infection in patients with febrile syndrome; however, to...
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Liver cirrhosis (LC) is an irreversible, chronic disease and constitutes the last clinical stage of many different liver diseases. The main cause of death is upper gastrointestinal bleeding caused by esophageal variceal rupture. We aim to depict the trend and estimate the morbimortality. For this, we conducted an ecological study and analyzed data...
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Recurrent positivity in a patient with COVID-19 may be due to various reasons, not necessarily reinfection. There is concern about the occurrence frequency of reinfection. Five databases and a preprint/preprint repository were searched. All case reports, case series, and observational studies were included. Bias was assessed for each study with the...
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Background The Latin American and Caribbean (LAC) region has been one of the regions most affected by the COVID-19 pandemic, with countries presenting some of the highest numbers of cases and deaths from this disease in the world. Despite this, vaccination intention is not homogeneous in the region, and no study has evaluated the influence of the m...
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Users of complementary and alternative medicine (CAM) have a lower intention to receive vaccines. Furthermore, Latin America and the Caribbean (LAC) region are among the most affected areas by the COVID-19 pandemics and present a high proportion of CAM users. Therefore, this study evaluates the association between the consumption of herbal suppleme...
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Background: High anthropometric indexes before sleeve gastrectomy (SG) are associated with an increased risk of erosive esophagitis (EE) in bariatric surgery candidates. Reasons that explain how these indexes influence the development of esophageal pathology after surgery remains unclear. Objectives: To assess the association between the body mass...
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Background: Acute respiratory infections (ARIs) are the most frequent respiratory diseases associated with the use of biomass as fuel within the home. ARIs are the main cause of mortality in children under 5 years of age. We aimed to evaluate the association between the use of biomass as cooking fuel and ARI in children under 5 years of age in Per...
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We aimed to assess the efficacy and safety of extracorporeal membrane oxygenation (ECMO) in patients under mechanical ventilation with COVID-19 and severe acute respiratory distress syndrome (ARDS). A systematic review of the literature published in PubMed, Cochrane Library and LILACS databases, was performed. A manual search was also conducted usi...
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Objective: We assessed the efficacy of colchicine in COVID-19 patients through a systematic review. Methods: Six databases were searched until March 2022 for studies assessing colchicine versus control in hospitalized patients with COVID-19. The primary outcome was mortality, and secondary outcome was length of hospitalization. Inverse variance...
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Background In March 2020, the Peruvian state introduced quarantine as a measure to control the spread of SARS-CoV-2. It has been suggested that being in quarantine is associated with the development of symptoms of Post-traumatic Stress Disorder (PTSD). The present study aims to explore the factors associated with the development of PTSD in a post-q...
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Background: In neonates with meconium aspiration syndrome (MAS), continuous positive airway pressure (CPAP) may be more beneficial compared to endotracheal intubation (ETI). We evaluated the efficacy of CPAP in neonates with MAS. Methods: Four engines were used to search randomized clinical trials (RCTs). We used relative risk (RR) and mean diff...
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Background Previous studies have suggested that the pandemic impact on mental health could vary according to gender. We aimed to evaluate the gender influence in the prevalence of depressive and anxiety symptoms in Latin American and the Caribbean (LAC) countries in the first stage of the COVID-19 pandemic. Methods We conducted a secondary analysi...
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Background: High anthropometric indexes before sleeve gastrectomy (SG) are associated with an increased risk of erosive esophagitis (EE) in bariatric surgery candidates. Reasons that explain how these indexes influence the development of esophageal pathology after surgery remains unclear. Objectives: To assess the association between the body mass...
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Previous studies have described multiple nutritional deficiencies after bariatric surgery (BS). However, few studies have evaluated these deficiencies prior to BS, specifically in Latin America. This study aimed to determine the factors associated with nutritional deficiency biomarkers in candidates for BS in Peru. We included adults of both sexes,...
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Introducción: El riesgo de prematuridad abarca una amplia variedad de complicaciones al nacer, como enfermedades infecciosas, hemorragia intraventricular, deficiencias neurosensoriales, insuficiencia respiratoria y afectación de otros sistemas, así como problemas de crecimiento y desarrollo. Por tanto, la consecución del Objetivo de Desarrollo del...
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Introduction: Community mitigation strategies (CMS) have demonstrated to be effective in the reduction of transmission and incidence of COVID-19, especially in the population with symptoms associated with the disease. The aim of this study was to evaluate the association between the presence of COVID-19 symptoms and adherence to CMS in Latin Ameri...
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We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according...
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Introducción: En el Perú, el programa actual de inmunización para COVID-19 comprende las vacunas BBIBP-CorV, BNT162B2 y ChAdOx1 nCoV-19. Si bien el esquema de inmunización es de dos dosis, algunos países han incluido recientemente una dosis de refuerzo a su esquema. Métodos: Se realizó una búsqueda de evidencia científica sobre la eficacia y seguri...
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We aimed to estimate the prevalence and factors associated with parents’ non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean (LAC). We performed a secondary analysis using a database generated by the University of Maryland and Facebook (Facebook, Inc., Menlo Park, CA, USA). We included adult...
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Introducción: Un adecuado abastecimiento de medicamentos en los establecimientos de salud aumentará la posibilidad de un adecuado control de la hipertensión y la diabetes. Objetivo: Determinar el desabastecimiento de antidiabéticos y antihipertensivos a nivel nacional en el contexto de la crisis por COVID-19. Material y métodos: Análisis del “Sis...
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Objective To determine the scientific production of doctoral graduates in Peru. Methods We made a descriptive cross-sectional study with a quantitative analysis approach of the scientific production of doctoral graduates in all areas of science registered in the National Council of Science, Technology and Technological Innovation of Peru. Results...
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Background Adolescent pregnancy carries a high risk of severe health issues for both the mother and the newborn. Worldwide, 21 million adolescents give birth every year, with high percentages in Latin America. Most of the risk factors are met in indigenous communities, which is an underrepresented and poorly studied population. We aimed to assess t...
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Objetivos: Estimar la prevalencia y los factores asociados a la intención de vacunación (IDV) contra la COVID19 en el Perú. Materiales y métodos: Estudio transversal analítico utilizando una encuesta realizada por la Universidad de Maryland,EUA, en Facebook. La variable dependiente fue la IDV. Se calcularon razones de prevalencia (RP) crudas y ajus...
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Spirulina is a cyanobacterium rich in proteins, polyunsaturated fatty acids, and bioactive compounds, such as C-phycocyanin, which has anti-inflammatory and antioxidant properties and possible lipid and glucose metabolism effects. This systematic review aimed to analyze the effects of spirulina on lipid profile, glucose metabolism, and anti-inflamm...
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Objective We assessed the prevalence of food insecurity (FI) and its associated factors in Latin American and the Caribbean (LAC) early during the COVID-19 pandemic. Methods We performed secondary data analysis of a survey conducted by Facebook and the University of Maryland. We included adults surveyed from April to May 2020. FI was measured by c...
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Purpose We aimed to evaluate the factors associated with intimate partner violence (IPV) against reproductive-age women in Peru. Methods Secondary analysis of the ENDES 2015-2017. ENDES is a multi-stage survey with a probabilistic sampling design for the urban and rural areas of the 25 regions of Peru. A total of 62,870 women of reproductive age (...
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Background Overexposure to ultraviolet (UV) radiation has increased skin cancer incidence and the risk of sunburns, especially during the summer months. Objective Identify the frequency and factors associated with sunburns in a sample of beachgoers in the northern coast of Peru. Methods We conducted a secondary data analysis of a previous study t...
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Background and aims The coronavirus disease 2019 (COVID‐19) outbreak has led to an unprecedented public health crisis. In Peru, although the quarantine is no longer mandatory, it was during the first months of 2020. To date, no studies have assessed the impact of the COVID-19 on the eating patterns and lifestyle context in the country. We aimed to...
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Objective To evaluate the association between the use of a 3D virtual App and academic performance among Peruvian medical students. In addition, factors associated with academic performance were also assessed. Methods We conducted an analytical cross-sectional study in students enrolled in the Musculoskeletal System course during the first semeste...
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Background: Determinants of vaccine acceptance are multifactorial, complex, and in most cases, context-dependent. We determined the prevalence of COVID-19 vaccination intention (VI) and fear of its adverse effects (FAE) as well as their associated factors in Latin America and the Caribbean (LAC). Methods: We conducted a secondary cross-sectional...
Preprint
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Objetivo: Determinar la prevalencia y factores asociados a la intención de vacunación (IDV) contra la COVID-19 en el Perú. Material y métodos: Estudio transversal analítico utilizando la encuesta realizada por Universidad de Maryland, EUA, en Facebook. Las variables dependientes fueron la IDV. Se calcularon razones de prevalencia (RP) crudas y ajus...
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Introducción: La Sociedad Científica Médico Estudiantil Peruana (SOCIMEP), a través de su Comité Académico, planifica y realiza actividades de educación médica, tales como conferencias y talleres. Objetivo: Describir las actividades académicas organizadas por las sociedades científicas de estudiantes de medicina (SOCEM) del Perú durante los años 2...
Preprint
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Background: To assess the outcomes of ivermectin in ambulatory and hospitalized patients with COVID-19. Methods: Five databases and websites for preprints were searched until January 2021 for randomized controlled trials (RCTs) and retrospective cohorts assessing ivermectin versus control in ambulatorys or hospitalized participants. The primary out...
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Background Peru is a Latin American country with a significant burden of hypertension that presents worrying rates of disparities in socioeconomic determinants. However, there is a lack of studies exploring the association between those determinants, hypertension and prehypertension in Peruvian population. Objective We aimed to assess the associat...
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Aim and Method To determine the effect on decisional-related and clinical outcomes of decision aids for depression treatment in adults in randomised clinical trials. In January 2019, a systematic search was conducted in five databases. Study selection and data extraction were performed in duplicate. Meta-analyses were performed, and standardised an...
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Objectives: Peer-assisted learning (PAL) is a supportive strategy in medical education. In Peru, this method has been implemented by few universities. However, there are no consistent studies evaluating their acceptability by medical students. The objective of this study was to evaluate the perception of medical students about PAL in five Peruvian...
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Background: General surgey is a specialty of high demand and relevance. We aimed to collect the opinions of the residents and their tutors and heads of department, regarding the impact that this COVID-19 pandemic is having - and will probably have - on the training of future general surgeons in Peru. Methods: We conducted a cross-sectional study...
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RESUMEN Introducción: En Latinoamérica, la prevalencia del síndrome de fragilidad en adultos mayores no institucionalizados de 60 años a más oscila entre 7,7 y 39,3 %. En Perú, pocos estudios han abordado este tema y sus factores asociados en poblaciones similares. Objetivo: Identificar la prevalencia de fragilidad y los factores asociados en adult...
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Objective To analyse the scientific production and collaboration networks on publications in systemic lupus erythematosus in Latin America. Materials and methods Bibliometric study between 1982 and 2018 of journals indexed in Scopus. Data were analysed by annual production and a co-occurrence analysis of the collaboration between countries with VO...
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We performed a bibliometric analysis of Latin American documents published between 1984 to 2019 in Scopus-indexed journals. A total of 1856 documents were analyzed. The annual scientific production was 64 documents per year, with an annual increase rate of 15.9%. The countries with the highest scientific production on BS were Brazil (64.7%) and Chi...
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La pandemia de enfermedad por coronavirus de 2019 (COVID-19) ha planteado diversos retos a los estamentos de la sociedad y la educación médica no ha sido la excepción. A nivel mundial, las universidades han planteado diversas iniciativas en el pregrado y el internado medico como la virtualización parcial de su contenido curricular, la modificación...