Carlos Soccol

Carlos Soccol
Universidade Federal do Paraná | UFPR · Departamento de Engenharia de Bioprocessos e Biotecnologia

PhD in Bioprocess Engineering

About

769
Publications
534,659
Reads
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28,781
Citations
Citations since 2017
273 Research Items
15673 Citations
201720182019202020212022202305001,0001,5002,0002,5003,000
201720182019202020212022202305001,0001,5002,0002,5003,000
201720182019202020212022202305001,0001,5002,0002,5003,000
201720182019202020212022202305001,0001,5002,0002,5003,000
Additional affiliations
July 2001 - present
Aix-Marseille Université
Position
  • Professor HDR
March 1993 - December 2015
Universidade Federal do Paraná
Position
  • Laboratory Heat
September 1979 - present
Federal University of Paraná - Brazil
Position
  • Professor (Full)

Publications

Publications (769)
Article
Lignocellulosic biomass is a renewable material of great abundance. However, its recalcitrant characteristic requires the application of pretreatments. Sugarcane bagasse (SB), soybean hulls (SH), cocoa pod husks (CPH) and oil palm empty fruit bunches (OPEFB) were subjected to imidazole pretreatment in order to evaluate chemical composition variatio...
Article
Full-text available
Soybean hulls (SH) are the main industrial waste from soybean processing, representing 5–8% of the whole grain. Imidazole was employed for the hydrothermal pretreatment of SH and further bioethanol production. Different pretreatment temperatures (120 and 180 °C) and times (1 and 3 h) were tested. Lignin removal and glucose yield were significantly...
Article
Soybean hulls are lignocellulosic residuesgeneratedinthe industrial processing of soybean, representing about 5% of the mass of the whole bean. This by-product isan importantsource of polymers suchas cellulose(34%) and hemicellulose (11%),which could bevalorizedvia biotechnology to improvethe economic returnof the oilseed chain. In the present work...
Article
This systematic review analyses the potential of cocoa residues for energy conversion using anaerobic digestion and evaluates strategies for optimizing methane production yields, retrieving information from papers published on anaerobic digestion of cocoa residues in journals indexed in Scopus, Web of Science, and PubMed databases. The articles wer...
Article
Full-text available
Main Conclusion Molecular studies have elucidated Trichoderma’s biocontrol mechanisms. Since fungicides have limited use, Trichoderma could control disease by new metabolic routes and epigenetic alterations. AbstractDue to environmental and health hazards, agrochemicals have been a concern since they were introduced in agriculture. Trichoderma, a w...
Article
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In this study, an investigation of the microbial community structure and chemical changes in different layers of a static coffee beans fermentation tank (named self-induced anaerobic fermentation-SIAF) was conducted at different times (24, 48, and 72 h). The microbial taxonomic composition comprised a high prevalence of Enterobacteriaceae and Nectr...
Article
Full-text available
Recycling bioresources is the only way to sustainably meet a growing world population’s food and energy needs. One of the ways to do so is by using agro-industry wastewater to cultivate microalgae. While the industrial production of microalgae requires large volumes of water, existing agro-industry processes generate large volumes of wastewater wit...
Chapter
Changes in human nutrition have promoted some intolerances, such as to lactose found in dairy products, which are highly consumed worldwide. This problem certainly impacts a significant percentage of the world population. But β-galactosidases appear to be an efficient and accessible solution, not only in the hydrolysis of lactose in dairy products,...
Chapter
The Bacillus genus is used for production of commercial enzymes and for various industrial products, including nutraceutics. The detailed knowledge of their genome, the ability to form spores and the wide range of substrates they can metabolize are some features justifying their importance in this field. They produce virtually all classes of enzyme...
Article
The high costs of bioplastics' production may hinder their commercialization. Development of new processes with high yields and in biorefineries can enhance diffusion of these materials. This work evaluated the production of polyhydroxybutyrate (PHB) from the combination of milled corn starchy fraction hydrolysate and crude glycerol as substrates b...
Preprint
Full-text available
Biological contamination is one of the main bottlenecks in the production of microalgae, reducing quality and productivity, sometimes leading to complete loss of the cultures. This work evaluated the presence of bacterial contaminants in N. oleoabundans cultures through HTS and 16S analysis and their susceptibility to 6 natural terpenes (α-pinene,...
Article
Full-text available
Cocoa beans fermentation is a spontaneous process, essential for the generation of quality starting material for fine chocolate production. The understanding of this process has been studied by the application of high-throughput sequencing technologies, which grants a better assessment of the different microbial taxa and their genes involved in thi...
Article
Sugarcane bagasse (SB) is a potential source for second-generation bioethanol production. Imidazole appears as a cheap green solvent that has demonstrated high efficiency in lignocellulosic biomass delignification. The main objective of this work was the use of imidazole-pretreated SB aiming the integration of first and second-generation bioethanol...
Chapter
This chapter explores the main microbial breeding techniques for 1G and 2G bioethanol production, including classical genetic strategies (induced mutations, clonal selection, sexual hybridization, artificial hybridization, and evolutionary engineering) and those based on genetic transformation (deletion and regulation of genes, pooled-segregant who...
Chapter
The aim of this chapter is to assess the stage of technological development and innovation in bioethanol production. For this purpose, two patent searches were conducted, one focused on pretreatment and saccharification and another on fermentation processes. The status of innovation was projected from industrial data. In the field of pretreatment a...
Chapter
Ethanol from biomass was the first fuel used by man in Otto cycle engines. Its substitution by petroleum derivatives followed naturally due to the logarithmic growth of the world’s demand for energy and limitations in agricultural growth. The so-called first generation (1G) ethanol produced from biomass with important levels of easily fermentable s...
Chapter
The world production of corn-bioethanol is currently led by the United States, followed by China and Brazil. As a starchy material, corn grains must pass through different pretreatment and enzymatic hydrolysis, which have an impact on final biofuel costs. In addition, a balance between the use of corn grains and their subproducts for food and feed...
Chapter
The search for new alternatives of fuels to compose an innovative and diversified energetic matrix available for countries is being the goal of a lot of research done worldwide. There are some essential steps to be well successful in this research. Especially for the biofuels development technology, involving the biofuels production through ferment...
Article
Full-text available
The development of immunosensors to detect antibodies or antigens has stood out in the face of traditional methods for diagnosing emerging diseases such as the one caused by the SARS-CoV-2 virus. The present study reports the construction of a simplified electrochemical immunosensor using a graphene-binding peptide applied as a recognition site to...
Article
Full-text available
The aim of the present study was to evaluate the use of supercritical CO2 combined with cosolvent for the recovery of bioactive compounds of soybean fermented with Rhizopus oligosporus NRRL 2710. Soxhlet extractions using seven different organic solvents (n-hexane, petroleum ether, ethyl acetate, acetone, ethanol, methanol, and water) were initiall...
Article
Soybean hull is a worldwide produced lignocellulosic waste from the soybean industrial sector. Its exploration through biotechnological approaches could increment considerably the value and economic return of soybean production-chain. The present study evaluated a citric acid pretreatment, an organic acid with eco-friendly characteristics and low i...
Article
The world has been searching for clean and renewable alternatives to provide new materials and energy and, consequently reducing the dependence on petroleum fossil fuels. Sugarcane has become an important raw material as a solution for this demand since it is grown in more than 100 countries and can potentially reduce greenhouse gas (GHG) emissions...
Article
It is imperative to search for appropriate processes to convert wastes into energy, chemicals, and materials to establish a circular bio-economy toward sustainable development. Concerning waste biomass valorization, hydrothermal carbonization (HTC) is a promising route given its advantages over other thermochemical processes. From that perspective,...
Article
Full-text available
The antioxidant and food pigment astaxanthin (AX) can be produced by several microorganisms, in auto- or heterotrophic conditions. Regardless of the organism, AX concentrations in culture media are low, typically about 10–40 mg/L. Therefore, large amounts of nutrients and water are necessary to prepare culture media. Using low-cost substrates such...
Article
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The use of yeasts as starter cultures was boosted with the emergence of large-scale fermentations in the 20th century. Since then, Saccharomyces cerevisiae has been the most common and widely used microorganism in the food industry. However, Candida species have also been used as an adjuvant in cheese production or as starters for coffee, cocoa, ve...
Article
Full-text available
Oil palm empty fruit bunches (OPEFB) were pretreated with imidazole aiming to reduce the biomass recalcitrance and to co-produce ethanol and succinic acid. For such as purpose, two different yeasts (Saccharomyces cerevisiae and Pichia stipitis) were evaluated and compared. Imidazole pretreatment of OPEFB at 180 °C for 1 h achieved a removal of 81.5...
Article
Full-text available
Lignin is an abundant biopolymer, as well as cellulose and hemicellulose. Thus, this work aimed at isolating and characterizing the lignin from Eucalyptus spp. Sawdust—a lignocellulosic waste generated in large amounts in sawmills—to evaluate its antioxidant capacity. A biorefinery perspective was utilized: the biomass was fractionated using a sequ...
Article
Full-text available
Rudimentary food fermentation can be defined as a spontaneous process of conversion of food components through enzymatic action. A great variety of fermented foods are produced using spontaneous approaches; however, cocoa and coffee represent the most important agricultural commodities on international markets. As a manner to increase the efficienc...
Article
Full-text available
Alkaline pretreatment and sequential enzymatic hydrolysis of soybean hull were investigated to obtain fermentable sugars for polyhydroxyalkanoates production along with residual glycerol as low-cost carbon sources. Soybean hull is composed of approximately 32% cellulose, 12% hemicellulose, 6% lignin, and 11% protein. Alkaline pretreatment was carri...
Chapter
Thermal analysis (TA) refers to a group of techniques used to investigate properties of a sample under programming of temperature and/or time in a particular atmosphere. TA was used initially as a standard method for the analysis of polymers. However, today it is known that the techniques also benefit the characterization of many other substances a...
Chapter
Aerobic granular sludge (AGS) is a promising wastewater treatment technology with advantages compared to the centenary conventional activated sludge process. This technology has been developed and tested for removal of nutrients as well as other pollutants present in both domestic and industrial wastewaters. A unified theory that completely describ...
Article
Full-text available
In the growing search for therapeutic strategies, there is an interest in foods containing natural antioxidants and other bioactive compounds capable of preventing or reversing pathogenic processes associated with metabolic disease. Fermentation has been used as a potent way of improving the properties of soybean and their components. Microbial met...
Article
Second-generation (2G) sugar is the principal building block in biorefineries producing sustainable fuels, green chemicals, and materials. Its production involves a pre-treatment strategy, which can remove either rhemicellulose or lignin, followed by a cellulase cocktail-mediated hydrolysis of pre-treated biomass applying numerous modifications. Th...
Article
The application of biorefinery concepts to produce different value-added biomolecules such as xylooligosaccharides (XOs) generates economical competitive, sustainable and environmentally friendly processes. The objective of this work was to develop an efficient imidazole-pretreatment process of sugarcane bagasse (SB) and the use of the obtained hem...
Chapter
The lipids production process involves many steps such as the selection of media components, cultivation of oleaginous microorganisms, lipid accumulation, biomass harvesting, and finally leach out of lipids. Agro-waste is an interesting renewable resource for sustainable biodiesel production because of its rich source of carbohydrates. Therefore, t...
Chapter
Production of green energy around the world has been increasing in recent decades, mainly due to the depletion of petroleum reserves, price hike in fossil fuels, and ecosystem contamination because of its combustion. Hence, the green energy has been adopted as renewable, sustainable, and alternative option to the fossil fuels. The use of microbial...
Book
Full-text available
Advances in Food Engineering, the latest release in the Current Developments in Biotechnology and Bioengineering series, is a unique source of state-of-art information about scientific and technological advances in food engineering. The book gives specific understanding of the engineering properties of food materials such as the morphological, phys...
Chapter
The complexity of the matrices of food materials increasingly requires studies in the development of fast and sensitive analytical techniques for the identification and quantification of compounds and constituent elements, added or contaminants in food. Due to great technological advances, mainly in the areas of data acquisition and treatment, spec...
Chapter
Microbial lipids can be used as food, feed, and nutraceuticals products. Their recovery from fermentation broths or microalgal cultivation requires dewatering and further extraction, followed by purification using processes similar to those applied for other fats and oils. The initial downstream steps are critical for the economical production of b...
Article
Sugarcane is one of the most promising biomass resources in the developing bioeconomy. It is a source of fermentable sugars and of lignocellulosic biomass that can be converted to a variety of products. Brazil is the leading producer of sugarcane, with 734 million tons projected for 2022 and a yield of 74 tons per hectare. Sugarcane is already an i...
Article
The discovery that yeasts are natural hosts for viruses in the 70s marked the beginning of research into yeast virology and, particularly, the killer yeast system. These viral sequences encode host toxin secretion, modulating microbial communities, and ecosystem functions in fermentation processes. Wine is the most frequently studied fermented food...
Article
Nowadays, there is a huge interest in first necessity products derived from biomaterials due to environmental concerns. A wide spectrum of biomaterials has been researched in several scientific areas. That is the case of the biopolymer poly-lactic acid (PLA). PLA's success has not started today; its studies have been launched since the 1980s. PLA i...
Article
Full-text available
Aroma and fragrance compounds have broad applications in the food, cosmetic and pharmaceutical industries. However, these compounds are mainly produced by chemical synthesis. An alternative, sustainable and promising route for the natural production of flavour compounds is microbial transformation processes. In this work, we obtained the production...
Article
Full-text available
Biorefineries are core units that convert biomass resources to energy and bioproducts, representing the sustainable alternative to traditional fossil-based processes. The market size of biorefineries is expected to reach U$D 52,680 million by 2027, at a compound annual growth rate of 2.2% in the period of 2021–2027 (MarketWatch, 2021). Among severa...
Article
Full-text available
The legal cannabis market worldwide is facing new challenges regarding innovation in the production of cannabinoid-based drugs. The usual cannabinoid production involves growing Cannabis sativa L. outdoor or in dedicated indoor growing facilities, followed by isolation and purification steps. This process is limited by the growth cycles of the plan...
Article
Immunoassays are practical and cost-effective approaches suitable for large-scale tuberculosis (TB) screening. This study identified new peptide mimotopes of Mycobacterium tuberculosis and applied them in the serodiagnosis of TB. Thereby, linear (X15, X8CX8) and constrained (LX-4 and LX-8) phage display peptide libraries were screened with purified...
Article
Full-text available
With the increasing participation of biomass in the world energy matrix, large amounts of ash are produced through combustion, resulting in the need to dispose of this waste to minimize the environmental impact. An alternative is to use ashes as phosphorus supplements in microalgae cultures. The present work describes the development and use of a b...
Article
The discrepancy between glucose over fructose metabolism during coffee fermentation can delay the drying process and stimulate the development of undesirable microorganisms. In this study, 26 lactic acid bacteria (LAB) isolated from laboratory-scale coffee fermentation were screened for their capacity to preferentially consume fructose over glucose...
Book
Full-text available
Current Developments in Biotechnology and Bioengineering: Technologies for Production of Nutraceuticals and Functional Food Products covers a wide range of topics related to the the microbial process for the production of high- value nutraceuticals and fermented functional foods. This reference includes the bioactive compounds derived from the food...
Chapter
Colostrum is secreted by the mammal’s glandules during the first days after parturition, it is rich in nutrients and bioactive molecules. This first milk is essential to guarantee the growth and immunity of the newborn, in addition to a balanced nutrition. The high immunoglobulin content in colostrum is responsible for the passive immunity from mot...
Chapter
Colostrum plays a decisive role in the survival and health of newborn mammals, serving as a source of energy for maintaining their homeostasis and as a source of immunoglobulins, acting passively in the formation of immunity. This chapter brings recent advances and approaches to obtain colostrum with improved qualities, whether for application to t...
Chapter
The global concerns about climate change have stimulated scientific researches and the establishment of governmental policies in order to slow greenhouse gases emissions, or even to mitigate them. Bioethanol and biodiesel, the most important transportation biofuels, play a central role in this scenario. Global bioethanol production has reached almo...
Chapter
The increasing demand for biofuels is a reality in the agricultural countries where the generation of starchy and/or lignocellulosic biomass is abundant. Each country has its own Governmental policies, laws, and incentives that boost the course for the establishment of performing and sustainable processes. These facts have created the search for ne...
Chapter
The environment is constantly and seriously affected by xenobiotic compounds such as insecticides, pesticides, fertilizers, plastics, and other hydrocarbon containing substances. There are many remediation ways to eliminate these pollutant components such as physical, chemical, and biological methods. Even though they may not be efficient and envir...
Chapter
The areal productivity and lipid yield of algal cultures created an expectation for algal biofuels, which is yet to be materialized; the projected prices for algal liquid fuels make them still uncompetitive. However, the market for microalgae products is growing in size and diversity, primarily for nutritional biomasses such as Spirulina or Chlorel...
Chapter
Full-text available
Microalgal cultures are assumed to be generally homogeneous—the same concentrations of nutrients, dissolved gases, and even cells are assumed throughout the culture volume. This approximation holds only if the system is continually mixed. In small laboratory cultures, a whole flask can be agitated in a shaker. However, it is essential to use mechan...
Chapter
Microalgae and thraustochytrids have appeared as an alternative renewable source of lipids in human nutrition, animal nutrition, and biofuels. These microbial lipids seek to meet the demands for high-value oils and reduce dependence on petroleum-based fuels. This chapter aims to study and provide concepts, trends, and innovations in terms of cultiv...
Chapter
Lipids from microbial sources are valuable substitutes of animal and vegetable oils, with potential applications such as food ingredients and supplements, biofuels, biolubricants, biosurfactants, and wax esters. They gained prominence as partial substitutes of fish-oil in specialty food products. Eicosapentaenoic acid, docosahexaenoic acid (omega-3...
Chapter
The ever-increasing energy demand has necessitated the identification of alternative renewable sources of energy. To this effect, oleaginous microorganisms provide an attractive sustainable alternative. The microbial lipids derived from these microorganisms can be utilized as biofuel or as a nutrition supplement. One of the roadblocks for the comme...
Chapter
The definition of bioprocesses’ parameters generally occurs at bench scale. However, the reproduction of these processes’ conditions at pilot and/or industrial scale is certainly a challenge. These conditions are for example aeration, which involves critical aspects such as dissolved oxygen and oxygen uptake rate, and agitation, which promotes shea...
Chapter
Soybean is one of the most abundant and cheap sources of high-quality vegetable protein. The most important suppliers of this commodity, as predicted for 2020/2021, are Brazil, the United States and Argentina, with 131, 112 and 53 million tons, respectively. China is expected to remain the greatest consumer (112 million tons). The main products obt...
Article
Traditionally, lipid-producing microorganisms have been obtained via conventional bioprospecting based on isolation and screening techniques, demanding time and effort. Thus, high-throughput sequencing combined with conventional microbiological approaches has emerged as an advanced and rapid strategy for recovering novel oleaginous microorganisms f...
Article
Full-text available
Cassava processing wastewater (CPW) is a highly polluting, liquid residue of cassava processing, usually discarded or treated anaerobically. However, it can serve as a low-cost culture medium for microalgae. After a preliminary evaluation of the growth of 10 microalgal strains in diluted CPW, the microalgae Haematococcus pluvialis SAG 34−1b and Neo...
Article
The aim of this work was to use the cocoa pod husks (CPHs) as a new substrate/support for citric acid (CA) production by Aspergillus niger strains in solid-state fermentation (SSF). Actually, CPH does not have a proper final destination, and its characteristics are suitable to be used as sole substrate in SSF for CA production. Partial physical-che...
Article
A biorefinery approach was applied for pectin extraction, xylooligosaccharides’ (XOs) and bioethanol production from cocoa pod husk (CPH) using citric acid-assisted hydrothermal pretreatment. Under optimal conditions at 120° C, 10 min and 2% w.v⁻¹ of citric acid a high pectin recovery (19.5%) with high content of uronic acids (41.9%) was obtained....
Article
Full-text available
Microbial activity is an integral part of agricultural ecosystems and can influence the quality of food commodities. During on-farm processing, coffee growers use a traditional method of fermentation to remove the cherry pulp surrounding the beans. Here, we investigated the influence of the coffee farm microbiome and the resulting fermentation proc...
Article
The objective of this work was to evaluate the potential of biohydrogen production in agro-industrial residues, which were soft drink wastewater (SDW), corn steep liquor (CSL), cheese whey (CW), and expired Guaraná soft drink, using one model strain Clostridium beijerinckii ATCC 8260 and newly isolated Clostridium butyricum DEBB-B348. The agro-indu...
Chapter
This book Biofuels and BioenergydOpportunities and Challenges fo- cuses on opportunities and challenges associated in commercial production of biofuels and bio- energy such as bioethanol, biodiesel, biogas, and biohydrogen by utilizing various sources ranging from microbial biomass, weeds, and waste and achieved through biochemical and thermochemic...