Carlos Polanco

Instituto Nacional de Cardiología · Department of Electromechanical Instrumentation

This Markov Chain Models book has been designed for undergraduated students of Sciences. It contains the fundamentals related to a stochastic process that satisfies the Markov property. To make the comprehension of this important concept easier, all the examples, exercises, and case studies are completely solved, and include both processes discrete...

Background From the existing knowledge of viruses, those infecting plants and bacteria and affecting animals are particularly interesting. This is because such viruses have an ability to vertically transmit to other species, including humans, and therefore could represent a public health issue of significant proportions. Objective This study aims...

Background: The Brugada syndrome (BrS) is a heart rhythm condition that is commonly associated with a strong predisposition for sudden cardiac death. Malignant ventricular arrhythmias could occur secondary to the dysfunction of the cardiac sodium voltage-gated Na(v)1.5 channel (SCN5A). Objective: This study aimed to perform a multiparametric com...

Background: Zika virus, which is widely spread and infects humans through the bites of Aedes albopictus and Aedes aegypti female mosquitoes, represents a serious global health issue. Objective: The objective of the present study is to computationally characterize Zika virus polyproteins (UniProt Name: PRO_0000443018 [residues 1-3423], PRO_000044...

In this chapter, we describe the main molecular features of SARS‐CoV‐2 that cause COVID‐19 disease, as well as a high‐efficiency computational prediction called Polarity Index Method®. We also introduce a molecular classification of the RNA virus and DNA virus families and two main classifications: supervised and non‐supervised algorithms of the pr...

Background In the vast variety of viruses known, there is a particular interest in those transmitted to humans and whose ability to disseminate represents a significant public health issue. Objective The present study’s objective is to bioinformatically characterize the proteins of the two main divisions of viruses, RNA-viruses and DNA-viruses. M...

Background The global outbreak of the 2019 novel Coronavirus Disease (COVID-19) caused by the infection with the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which appeared in China at the end of 2019, signifies a major public health issue at the current time. Objective The objective of the present study is to characterize the phy...

Background/Objective AUGUSTUS trial demonstrated that, for patients with atrial fibrillation (AF) having acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI), an antithrombotic regimen with apixaban and P2Y12 resulted in less bleeding, fewer hospitalizations, and similar ischemic events than regimens including a vita...

Background Selective Cationic Amphipathic Antibacterial Peptides (SCAAPs) occupy a prominent place in the production of new drugs on account of their high toxicity towards bacteria and low toxicity towards mammalian cells, low hemolytic activity, and contribution to the protection of the human immune system. Introduction Their number in nature is...

Exterior Calculus book has been designed for third-year students of Sciences, as it contains the fundamentals related to Grassmann algebra oriented to Calculus. Without any doubt, this algebra has important implications in Science and Engineering. Here, the reader will find a clear presentation of the Grassmann algebra on a plane and in space, as w...

Background: The dynamic interactions of severe infectious diseases with epidemic potential and their hosts are complex. Therefore, it remains uncertain if a sporadic zoonosis restricted to a certain area will become a global pandemic or something in between. Objective: The objective of the study was to present a surveillance system for acute sev...

Background The female Aedes aegypti mosquito is a vector of several arthropodborne viruses, such as Mayaro, Dengue, Chikungunya, Yellow Fever, and Zika. These viruses cause the death of at least 600000 people a year and temporarily disable several millions more around the world. Up to date, there are no effective prophylactic measures that would pr...

Differential calculus is an essential mathematical tool for physical and natural phenomena analysis; it is a very important subject for students in the Faculties of Science and Engineering. This ebook has been designed to cover one academic semester for first-year students, as it contains the fundamentals related to this discipline. Here, the reade...

Background: Measurement of intra-abdominal pressure (IAP) is realized with the Kron's method. However, this technique has drawbacks like an infusion of water into the bladder of the patient. Objective: The prove a new novel disposable sensor in the way to measure the IAP (DSIAP) this one addresses some limitations of the Kron method. Materials...

The Brugada syndrome (BrS) is a disease with a great predisposition to sudden cardiac death due to ventricular arrhythmias. Dysfunctional ion channels are considered responsible for this entity. To date, there are 4,388 overrepresented BrS mutated proteins underlying this disease reported in the UniProt database. In an effort to characterize protei...

NaClO3 is achiral in solution. If crystallization is performed under a static set-up, it is recognized that the stochastic nucleation probability results in a racemic mixture of the conglomerate. In this paper, we report a reexamination of the crystallization of NaClO3 from static solution in petri dishes that was conducted over a number of years a...

Differential calculus is an essential mathematical tool for physical and natural phenomena analysis; it is a very important subject for students in the Faculties of Science and Engineering. This ebook has been designed to cover one academic semester for first-year students, as it contains the fundamentals related to this discipline. Here, the reade...

Electronic and computational system oriented to detect cluster Aedes aegypti mosquitoes.

Electronic and computational system oriented to detect cluster Aedes aegypti mosquitoes.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

Scientific product added to the company MATH BOTS SOLUTIONS, S.A.S.

In the last two decades, a group of proteins whose mutations are associated with a disease manifested by episodes of muscle weakness (periodic paralysis), changes in heart rhythm (arrhythmia), and developmental abnormalities has been under constant study. This malady is known as Andersen–Tawil syndrome, with ~60% of cases of this syndrome being cau...

Program that develops epidemiological surveillance, using stochastic variables. Country: México.

Computational program that identifies the preponderant function of a protein, using eigenvectors. Country: México.

Computational program that identifies the preponderant function of a protein, using eigenvectors. Country: México.

Program that develops epidemiological surveillance, using stochastic variables. Country: México.

Computational program that simulate the construction of proteins. Country: México.

Computational program that simulate the construction of proteins. Country: México.

In this work, we present a stochastic computational model that recreates the formation of prebiotic peptides from a set of 20 proteinogenic amino acids, taking into account their molecular weight, polarity, and thermal decomposition. The model simulates the recombination, fragmentation, and self-replication of the peptides. The results show great s...

Business plan and Feasibility study focus on the size of the Mexican potential market.

Business plan and Feasibility study focus on the size of the Mexican potential market.

The number of fatalities and economic losses caused by the Ebola virus infection across the planet culminated in the havoc that occurred between August and November 2014. However, little is known about the molecular protein profile of this devastating virus. This work represents a thorough bioinformatics analysis of the regularities of charge distr...

Computational program Program that develops epidemiological surveillance. Country México.

Computational program Program that develops epidemiological surveillance. Country México.

The carbonaceous chondrite meteorites (CM2) with high contents of organic material, water, and amino acids, might have been the main source of the amino acids of Earth's biosphere. Based on this conjecture, the relative abundance of the biologically relevant amino acids found in the CM2 meteorites could be observed in contemporary proteins. To veri...

In recent decades a group of enzymes produced by bacteria called β-lactamase has been in constant study due to its ability to provide bacteria with multi-resistance to β-lactam antibiotics such as carbapenems, cephalosporins, monobactams, and penicillins. This work presents a metric that identifies characteristic features of this important group of...