Carlos Lobato

Carlos Lobato
Universidad Juárez Autónoma de Tabasco | UJAT · División Académica de Ciencias Básicas

PhD

About

41
Publications
7,339
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304
Citations
Citations since 2017
16 Research Items
217 Citations
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Introduction
Carlos Lobato currently works at the División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco. Carlos does research in Green Chemistry, Organic Chemistry and Phytochemistry. Their current project is 'molecular transformations of natural products, organic chemistry, nmr spectroscpy'.

Publications

Publications (41)
Article
Full-text available
Several Mesoamerican cultures have used Inga jinicuil as traditional medicine for the treatment of gastrointestinal, inflammatory, and infectious issues. The aims of this contribution were to elucidate the phytochemical profile of the organic extracts from the bark and leaves of I. jinicuil and to assess the anti-inflammatory and antibacterial prop...
Article
Full-text available
Three functionalized chalcones containing combinations of nitro functional groups have been synthesized via Claisen-Schmidt condensation between 2-nitroacetophenone and nitrobenzalde-hyde, and the crystal structures obtained ((E)-1,3-bis(2-nitrophenyl)prop-2-en-1-one, 1a, (E)-1-(2-nitrophenyl)-3-(3-nitrophenyl)prop-2-en-1-one, 1b and (E)-1-(2-nitro...
Article
Ethnopharmacological relevance: Haematoxylum campechianum L., is a well-known plant in the southeast region of Mexico, where it is named as "palo tinto" or "palo de Campeche", in English there are vernacular names such as "redwood", "bloodwood tree" or "campeachy wood". Traditional medicine refers its use for the treatment of different disorders i...
Article
Full-text available
An overview of current Mexican legislation regarding soil restoration and updating needs is made through the analysis of three case studies located in the southeastern México: a) soil affected by spillage of congenital waters (Zone 1), b) soil contaminated by hydrocarbons (Zone 2) and, c) a site adjacent to urban infrastructure (Zone 3). It was per...
Article
The objective of this review is to describe the origin and state of the art of proline-derived long-aliphatic-chain amphiphilic organocatalysts (PDLACAOs), from the report of the first catalyst by Barbas III in 2006 until this year. The use of catalysts for asymmetric organic reactions in aqueous media (water, brine, and sea water), including in wa...
Preprint
Full-text available
Aristolochia odoratissima L. is employed for the treatment of pain and as an antidote against the poison of venomous animals in traditional medicine. However, reports have not been found, to our knowledge, about the evaluation of the antinociceptive activity of extracts nor about the presence of compounds associated with this activity. Thus, the pu...
Article
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A method was developed to determine °API from the relative abundance of polar and aliphatic functional groups as measured by FTIR. Twenty-two samples of petroleum were collected from the southern region of Mexico and analyzed by FTIR using an Attenuated Total Reflectance (ATR) accessory. API gravity was run in parallel using the convention hydromet...
Article
According to the search in the state of the art, no antecedents were found in which photocatalytic degradation of 17α-methyltestosterone (MT) hormone has been carried out using doped-TiO2. Nor have the transformation products formed during the heterogeneous photocatalysis (FH) been identified. Therefore, in this study we analyzed the photocatalytic...
Article
Full-text available
En México, los suelos impactados por hidrocarburos son remediados mediante diversas técnicas, algunas reducen la concentración del contaminante y otras lo estabilizan; es por ello que las condiciones finales dependerán del proceso aplicado. Al no considerar esta situación, algunas áreas restauradas con vocación de uso agrícola-ganadera presentan pr...
Article
Full-text available
Gómez-Rivera et al, Afr J Tradit Complement Altern Med., (2018) 15 (4): 72-82 https://doi. Abstract Background: Salvia gesneriflora Lindley is employed in traditional Mexican medicine for the treatment of several diseases. This work reports the spasmolytic, anti-inflammatory and antioxidant activities of salvia gesneriflora Materials and Methods: T...
Article
Full-text available
Background: Salvia gesneriflora Lindley is employed in traditional Mexican medicine for the treatment of several diseases. Materials and Methods: The chromatographic profile of three extracts (SgH, SgD and SgM) of this plant allowed the identification of 11 components in SgH, the presence of rosmarinic (1), chlorogenic (2) and caffeic (3) acids and...
Article
Full-text available
La escuaramida y sus derivados representan un importante grupo de sustancias que actualmente se están aplicando exitosamente en estrategias de organocatálisis asimétrica. En esta contribución se presenta un resumen del estado del arte relativo a la síntesis de los derivados de escuaramida y su papel como inductores de quiralidad en secuencias sinté...
Article
Full-text available
Se compararon perfiles edafológicos, parámetros fisicoquímicos y textura de dos sitios con fuerte impacto antropogénico, contra un sitio no impactado, localizados en el interior del campus universitario de la División Académica de Ciencias Básicas (DACB) de la Universidad Juárez Autónoma de Tabasco (UJAT); asimismo se dio seguimiento a un programa...
Article
Full-text available
Haematoxylum campechianum is a medicinal plant employed as an astringent to purify the blood and to treat stomach problems such as diarrhea and dysentery. A bio-guided chemical fractionation of the methanolic extract obtained from this plant allowed for the isolation of five compounds: two chalcones known as sappanchalcone (1); 3-deoxysappanchalcon...
Article
Full-text available
Being located in the largest mainland oil production zone of Mexico, the region of the Plains and Swamps of Tabasco is vulnerable to petroleum products spills, including oils used in production and residual water. The latter contain components considered as toxic. In the state of Tabasco there have been environmental emergencies due to spills in th...
Article
Full-text available
In many petroleum-producing regions, there are not adequate controls to prevent pipeline breaks and spills, and thus soil is frequently contaminated with petroleum hydrocarbons. Different petroleum oil compounds may produce negative impacts on soil fertility. In this study, four fresh crudes, a weathered petroleum, and oils from bioremediated and b...
Article
Full-text available
The extraction of plant constituents is essential to isolate biologically active compounds, aimed to understand their role on the treatment of diabetes.This study was designed to explore the preliminary phytochemical and physicochemical analysis of Carica papaya L., Caricaceae, leaf, and further evaluation of its hypoglycemic effect on diabetic rat...
Article
The three new compounds (III) show antiinflammatory protective, time dependent effect by both oral and intraperitoneal administration.
Article
Full-text available
The unit-cell dimensions and space group of the second monoclinic polymorph of the title compound, C 15 H 11 FO, differ from those of the previously reported form [Jing (2009). Acta Cryst. E 65 , o2515]. The title compound shows an E conformation of the C=C bond with the 4-fluorophenyl group opposite to the benzoyl group. The torsion angle of betwe...
Article
Full-text available
The aim of this study was to synthesize three nitro substituted chalcones and to evaluate their anti-inflammatory activity in the model of carrageenan induced edema in rats. The nitro chalcone were prepared by aldol condensation using of mechanical agitation and environmentally friendly solvents with 72-73% yields in approximately 2h. The three str...
Article
Full-text available
The asymmetric unit of the title compound, CHNO, contains two mol-ecules in both of which the six-membered 1,3-dioxane-4,6-dione ring shows a screw-boat conformation. The dihedral angles between the best planes through the six-membered rings are 47.8 (2) and 49.8 (2)°. In the crystal, C-H⋯O inter-actions link the mol-ecules, building a supramolecul...
Article
Full-text available
was to investigate the in vivo and in vitro cardiovascular activity of a procyanidin fraction (PCF) obtained from acetone extract of Guazuma ulmifolia bark which has traditionally been used as an antihypertensive agent. 10 mg/kg PCF doses orally administered to sugar-fed hypertensive rats decreased both the systolic arterial pressure and the heart...
Article
Full-text available
Four N-substituted piperidines and four N-substituted pyrrolidines were synthesized and characterized by common spectroscopic techniques. In order to investigate the dynamic behavior of these important heterocyclic building blocks, a conformational study was carried out, using suitable tools of computational chemistry. The comparison of computed an...
Article
Full-text available
5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-hept-4,6-dien-3-one(C21H22O6) crystallizes into triclinic, P1. The unit- cell dimensions at 293 K are a = 7.4733(6), b = 11.4315(9), c = 12.7458(10)Å, α = 113.272(2), β = 103.374(2), γ = 97.340(2)°C, V = 943.46(13)Å3, Dx = 1.304 g/cm3, and Z = 2. The R value is R = 0.050 for 3333 reflections. The molecul...
Article
Full-text available
New heterocyclic derivatives of curcumin (3) of different ring size were synthesized by reaction of a key intermediate, 1,7-bis(4-acetoxy-3-methoxyphenyl)hepta-3,5-dione (5) with some bi-nucleophilic molecules. These new synthetic derivatives were obtained in good yields and the structure of all compounds was supported by MS, IR, 1D and 2D 1H and 1...
Article
C25H28O8 is monoclinic, P21. The unit-cell dimensions at 293 K are a = 8.054(1), b = 9.438(2), c = 15.701(1)A, β = 98.875 (2)°, V = 1179.1(2)A3, Dx = 1.286 g/cm3, and Z = 2. The R value is R = 0.046 for 4152 reflections. There is an intramolecular hydrogen bond with an O2…O1 distance of 2.496(1)A. The molecules in the crystal are packed at the norm...
Article
The reaction of 2,4-pentanedione (1) with (R)-(—)-2-phenylglycine methyl ester (2), (R)-(—)-2-phenylglycinol (3) and the proteinogenic amino acids (2S,3R)-(—)-2-amino-3-hydroxybutyric acid (L-threonine) (4) and (R)-(—)-2-amino-3-mercaptopropionic acid (L-cysteine) (5) methyl esters was investigated. The corresponding enamines 6, 7 and 8 were isolat...
Article
The reaction of 2,4-pentanedione (1) with (R)-(-)-2-phenylglycine methyl ester (2), (R)-(-)-2-phenylglycinol (3) and the proteinogenic amino acids (2S,3R)-(-)-2-amino-3-hydroxybutyric acid (L-threonine) (4) and (R)-(-)-2-amino-3-mercaptopropionic acid (L-cysteine) (5) methyl esters was investigated. The corresponding enamines 6, 7 and 8 were isolat...

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Projects (3)
Project
search for bioactive compounds, nmr and x-ray spectroscopic studies, new molecular transformations of natural products, organic reactions