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Carlos Gamez Cabrera

Carlos Gamez Cabrera

PhD

About

10
Publications
1,174
Reads
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24
Citations
Citations since 2016
1 Research Item
10 Citations
20162017201820192020202120220123456
20162017201820192020202120220123456
20162017201820192020202120220123456
20162017201820192020202120220123456
Introduction
Ph. D. in Chemistry with extensive experience in research in Photochemistry and Microbiology as well as in university teaching of Organic Chemistry. Able to perform efficiently multidisciplinary tasks and to work under pressure. Resolute attitude and ability to lead large groups of people. Carlos Gámez Cabrera worked at the Departamento de Química, Simon Bolívar University until august 2018. Carlos does research in Chemical Engineering, Medicinal Chemistry and Organic Chemistry. Their current project is 'Synthesis and evaluation of new hetero chalcones derived from thiophene for possible application as photodynamic inactivators of phytopathogenic bacteria'.
Additional affiliations
January 2016 - August 2018
Simon Bolívar University
Position
  • Investigator
Description
  • Interest Areas/Research Lines: Organic Synthesis, Natural Products, Organic Photochemistry, Photophysic and Photobiology. Microbiology, Antimicrobial assays. Bacterial Photoinactivation and Photodynamic Therapy.
January 2016 - August 2018
Simon Bolívar University
Position
  • Professor
Description
  • Organic chemistry section.
January 2011 - December 2015
Simon Bolívar University
Position
  • Professor (Assistant)
Description
  • Organic chemistry section.
Education
December 2010 - December 2015
Simon Bolívar University
Field of study
  • Chemistry
November 2008 - November 2010
Simon Bolívar University
Field of study
  • Chemistry
September 2003 - November 2008
Simon Bolívar University
Field of study
  • Chemical engineering

Publications

Publications (10)
Article
Three new Z-chalcone derivatives were synthesized under stereoselective conditions by condensation between an aldehyde derivative (prepared from aloe-emodin) and an acetophenone, using potassium hydroxide in dimethyl sulfoxide/H2O at room temperature. The Z configuration of the chalcone derivatives was established by nuclear magnetic resonance (NMR...
Article
Full-text available
13,14-Dihydroxy-8,11,13-podocarpatrien-7-one (1) and a series of ring C aromatic diterpene derivatives were synthesised from (+)-manool (4) and evaluated for their cytotoxic, leishmanicidal and trypanocidal activities. Our results indicated that compound 1 and other podocarpane-type intermediates are cytotoxic. Cleavage of C6-C7 bond of compound 7...
Article
Full-text available
14,15,17-Trinorlabdan-8,13-dione 6 was efficiently synthesized via ozonolysis of(+)-manool (4) followed by treatment with aqueous NaOH in the presence of tetra-n-butylammonium bromide as catalyst. This protocol has the advantages of high yield, mild conditions and simple procedure. Utilizing this strategy, the first enantiospecific synthesis of 13,...
Poster
Full-text available
Patent blue V (PBV) dye is used to localize the sentinel lymph node during breast and uterine oncological surgery. Anaphylactic reactions related to patent blue dye are described in the literature. Outside medicine it is used in textiles and as a food colorant (E 131) and potentially exposes the general population to the risk of allergic sensitizat...
Article
A convenient synthesis of the natural (+)-13-hydroxypodocarpa-8,11,13-triene 1 and (+)-7-deoxynimbidiol 2 from (+)-manool 4 has been achieved in good overall yield.
Article
Full-text available
Facile access to optically active ring C aromatic diterpenes from (+)-manool. Synthesis of (+)-13-hydroxypodocarpa-8,11,13-triene, (+)-7-deoxynimbidiol and (+)-nimbidiol A practical method for the synthesis of naturally occurring ring C aromatic diterpenes from (+)-manool via key intermediate β-enone is described. The natural (+)-13-hydroxypodocarp...

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Projects

Project (1)
Project
The main objective of this project is to prepare, characterize and evaluate the photophysical and photobiological properties of a new series of thiophene derived heterochalcones in order to explore its possible application in the treatment of phytopathogenic bacteria by photoactivation with UV-Vis light.