Carlos Adam Conte Junior

Carlos Adam Conte Junior
Federal University of Rio de Janeiro | UFRJ · Departamento de Bioquímica

D.V.M., M.Sc., Ph.D.
Professor

About

437
Publications
151,570
Reads
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5,597
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Introduction
Carlos A. Conte-Junior is Professor of Biochemistry from Federal University of Rio de Janeiro, Brazil. Bachelor's at Veterinarian Medicine from Fluminense Federal University, Master's at Food Science and Technology from Rio de Janeiro Federal University, doctorate at Veterinary Medicine from Fluminense Federal University, Ph.D. at Food Science and Technology from Universidad Complutense de Madrid (UCM) with stay in Vrije Universiteit Medisch Centrum Amsterdam (VUmc), post-doctorate in Karolinska Institute (Sweden) and post-doctorate in University of California (USA). Has more than 240 Peer-Reviewed Journal Articles, 2 Technical Articles, 13 Invited Book Chapters, 48 Full-Paper Conference Proceedings, and 148 Refereed Abstracts.
Additional affiliations
January 2013 - July 2022
Federal University of Rio de Janeiro
Position
  • Professor (Full)
March 2010 - March 2019
Universidade Federal Fluminense
Position
  • Professor (Full)

Publications

Publications (437)
Article
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Bioactive compounds represent a broad class of dietary metabolites derived from fruits and vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer prevention. Curcumin, resveratrol, quercetin, and β-carotene have been the most widely applied bioactive compounds in chemoprevention. Lately, many approaches to encapsu...
Article
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The quest for novel anti-diabetic medication from medicinal plants is very important since they contain bioactive phytochemicals that offer better activity and safety compared to conventional therapy. In the present study, in vitro, in vivo and in silico approaches were explored to evaluate the anti-inflammatory, antioxidants, and hypoglycemic acti...
Article
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The present study evaluated the polyphenolic contents and hypoglycemic, antioxidant, and anti-inflammatory effects of the diethyl ether fraction of Thespesia garckeana using various in vitro and in vivo models. Total phenol and flavonoid contents of the extract were 613.65 ± 2.38 and 152.83 ± 1.56 mg/100 g dry weight, respectively. The extract exhi...
Article
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Essential oil nanoemulsion may have improved antibacterial properties over pure oil and can be used for food preservation. Ultrasonic cavitation is the most common mechanism for producing nanoemulsions, and the impact of processing parameters on droplet properties needs to be elucidated. A systematic literature search was performed in four database...
Article
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Biosensors are a simple, low-cost, and reliable way to detect pesticides in food matrices to ensure consumer food safety. This systematic review lists which nanomaterials, biorecognition materials, transduction methods, pesticides, and foods have recently been studied with biosensors associated with analytical performance. A systematic search was p...
Article
Brazilian Amazon contains over 30,000 plant species and foods rich in bioactive compounds such as terpenes, phenolic acids, alkaloids, and flavonoids, of potential health benefits (antioxidant, antimicrobial, antiparasitic, anticancer, gastroprotection, prebiotic effects, among others). The existence of residues from non-edible parts of plants (lea...
Article
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Four Escherichia coli isolates with moderate or high heat resistance were sequenced. Through sequencing, truncated transmissible locus of stress tolerance (tLST) variants tLST1 and tLSTa were identified in the three isolates. The most identified tLST genes (clpK and hsp) are responsible for the homeostasis module.
Article
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The aim of the present study was to evaluate the sensory acceptability limit of refrigerated fish through a multivariate approach, involving classic physicochemical and bacteriological indicators and considering different consumer profiles. The results of the survival analysis demonstrated that, in general, consumers still considered the fish to be...
Article
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The second wave of coronavirus disease 2019 (COVID-19) caused severe infections with high mortality. An increase in the cases of COVID-19-associated mucormycosis (CAM) was reported predominantly in India. Commonly present in immunocompromised individuals, mucormycosis is often a life-threatening condition. Confounding factors and molecular mechanis...
Article
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The amino acid L-arginine is crucial for nitric oxide (NO) synthesis, an important molecule regulating vascular tone. Considering that vascular dysfunction precedes cardiovascular disease, supplementation with precursors of NO synthesis (e.g., L-arginine) is warranted. However, supplementation of L-citrulline is recommended instead of L-arginine si...
Article
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Purpose Capsaicin (CAP) has been demonstrated to activate the transient receptor potential cation channel subfamily V member 1 (TRPV1), which can regulate nitric oxide production and, consequently, affect oxygen delivery to the muscles. In addition, TRPV1 activation can lead to calcium release from the sarcoplasmic reticulum, which is crucial for o...
Article
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For many years, milk proteins have been included in human nutrition and as an ingredient in several products. In recent years, studies have sought to propose milk proteins as natural carriers for bioactive compounds and develop nanostructures containing these compounds. Although most bioactive compounds have beneficial effects on health, some limit...
Article
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Doxorubicin (DOX) is an anticancer agent for treating solid and soft tissue malignancies. However, the clinical use of DOX is restricted by cumulative, dose-dependent cardiotoxicity. Therefore, the present study aimed to assess the cardioprotective effects of P. ginseng C. A. Mey, febuxostat, and their combination against DOX-induced cardiotoxicity...
Article
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Doxorubicin (DOX) is an anticancer agent for treating solid and soft tissue malignancies. However, the clinical use of DOX is restricted by cumulative, dose-dependent cardiotoxicity. Therefore, the present study aimed to assess the cardioprotective effects of P. ginseng C. A. Mey, febuxostat, and their combination against DOX-induced cardiotoxicity...
Article
Many people around the world are concerned about meat safety and quality, which has resulted in the ongoing advancement of packaged food technology. Since the emergence of graphene in 2004, the number of studies on layered two-dimensional materials (2DMs) for applications ranging from food packaging to meat quality monitoring has been expanding qui...
Article
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The inhibitory potential of Artemisia annua, a well-known antimalarial herb, against several viruses, including the coronavirus, is increasingly gaining recognition. The plant extract has shown significant activity against both the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the novel SARS-CoV-2 that is currently ravaging the world...
Article
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Inorganic nanoparticles (NPs) and natural antioxidant compounds are an emerging trend in the food industry. Incorporating these substances in biobased and biodegradable matrices as polysaccharides (e.g., starch, cellulose, and chitosan) and proteins has highlighted the potential in active food packaging applications due to more significant antimicr...
Article
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This study aimed to detect the impact of Moringa oleifera leaf powder dietary inclusion on the antioxidant and innate immune responses of mono-sex Nile tilapia fingerlings. A total of 180 fingerlings were allocated in a random method into three groups with triplicate each. One group (1st group) received the control diet (basal diet (BD) free of mor...
Article
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This study revealed the possible effects of various levels of silver nanoparticle (AgNP) application on plant diseases and soil microbial diversity. It investigated the comparison between the application of AgNPs and two commercial nanoproducts (Zn and FeNPs) on the rhizobacterial population and Botrytis fabae. Two experiments were conducted. The f...
Article
Milk is one of the main foods present in the human diet. It is a good source of many essential nutrients; however, milk is among the most adulterated food globally. This study investigated the potential of low-cost portable spectroscopy near-infrared (NIR) and energy-dispersive X-ray fluorescence (EDXRF) spectrometry combined with chemometric tools...
Article
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Mercury (Hg) contamination has increased in the last decades, resulting in human consumption concerns mainly in developing countries. In this context, this study aimed to carry out a health risk assessment regarding the consumption of swimming crabs, shrimp and squid species caught in different regions of the Guanabara Bay, Rio de Janeiro, Brazil....
Article
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Gentamicin (GEN) is a bactericidal aminoglycoside known to cause nephrotoxicity. Formononetin (FN) is a potent flavonoid that exhibits numerous promising pharmacological activities. In this study, we have assessed the nephroprotective efficacy of FN against GEN-induced renal injury in rats. Rats were orally administered with FN (60 mg/kg/day, for 2...
Article
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Goat milk (GM) is an excellent alternative to cow milk and has recently been used in commercial infant formula preparation due to its superior fat composition. Here, the fatty acid (FA) compo-sition, triacylglycerol (TAG) molecular species, thermal behavior and infrared spectra of extracted milk fat from the milk of the two main breeds of dairy goa...
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The widespread usage of nanotechnology in many essential products has raised concerns about 24 the possible release of nanoparticles (NPs) into aquatic habitats. Cerium dioxide (CeO 2) has gained the most 25 interest in the worldwide nanotechnology industry of all types of Ce minerals owing to its beneficial uses in a 26 wide range of industry prac...
Preprint
Bovine mastitis is an inflammation of mammary gland parenchyma in cows. It is caused by multiple pathogens including bacteria and fungi. Mycotic mastitis is a secondary disease following improper frequent use of antibiotics or an unhygienic environment. The treatment of rising cases of mycotic mastitis is still controversial because of the rapid re...
Article
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Nanotechnology experienced a great technological advance after the discovery of the graphene family (graphene – Gr, graphene oxide – GO, and reduced graphene oxide-rGO). Based on the excellent properties of these materials, it is possible to develop novel polymeric nanocomposites for several applications in our daily routine. One of the most promin...
Article
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This study aimed to investigate through free word association the perception of Brazilian consumers regarding the possibility of infection with the SARS-CoV-2 virus through food. One thousand individuals answered the questionnaire via an online platform. Most cited terms (hygiene-8%, fear-8%, caution-5%) and categories (negative attitudes and feeli...
Article
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Infant formulas are the main nutritional source for infants when breastfeeding is not possible or recommended. The daily need for specific nutrients, such as essential minerals, in early stages of a child's life is high because of rapid infant growth and development, which impose metabolic flux increases on these pathways to support growth, physica...
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Fiber-enriched food has numerous health benefits. This study develops functional fiber-enriched pasta (FEP) by partially substituting wheat flour for alcohol-insoluble residue prepared from potato processing byproducts (AIR-PPB) at various particle sizes (PS). The independent variables’ effects, AIR-PPB at 2–15% substitution levels, and PS 40–250 µ...
Article
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Colorectal cancer (CRC) is one of the most common and reoccurring diseases, as well as the world’s second largest cause of mortality. Despite existing preventative, diagnostic, and treatment methods, such as chemotherapy, the number of instances rises year after year. As a result, new effective medications targeting specific checkpoints should be d...
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Drug-induced liver injury (DILI) is the main cause of liver damage mediated by the excretion of toxic active drug metabolites. Omega-3 fatty acids and vitamin C have potent antioxidant, anti-inflammatory, and antiapoptotic effects that could offer protection against oxidative stress and liver damage. This study evaluated the hepatoprotective effect...
Article
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The growth of spoilage and pathogenic bacteria during storage represents significant losses in marketing raw milk cheeses. Thus, reducing NaCl in these products is challenging, as sodium has a critical antimicrobial role. Despite advances in non-thermal technologies, the short shelf life still limits the availability of raw goat cheese. Thus, combi...
Article
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Fruit juices (FJs) are frequently taken owing to their nutritious benefits, appealing flavour, and vibrant colour. The colours of the FJs are critical indicators of the qualitative features that influence the consumer's attention. Although FJs' intrinsic acidity serves as a barrier to bacterial growth, their enzymatic stability remains an issue for...
Article
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In the present study a single screen-printed carbon electrode (SPCE) and chemometric techniques were utilized for forensic differentiation of Brazilian American lager beers. To differentiate Brazilian beers at the manufacturer and brand level, the classification techniques: soft independent modeling of class analogy (SIMCA), partial least squares r...
Article
Trace metals such as lead and mercury can be present in beverages by contamination during production and storage processes, or by the use of hops and brewing grains that may be contaminated with trace metals. Since these metals are harmful to human health, their presence is strictly controlled by regulatory agencies. In this aspect, the present wor...
Article
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A novel severe acute respiratory distress syndrome coronavirus type 2 (SARS-CoV-2) has been confirmed as the cause of the global pandemic coronavirus disease 2019 (COVID-19). Different repurposed drugs have been trialed and used in the management of COVID-19. One of these agents was the anti-cancer Selinexor (SXR). SXR is an anti-cancer drug that a...
Article
Polycyclic aromatic hydrocarbons (PAHs), the main component of petroleum, are a concern due to their environmental persistence, long-range transport, and potential toxic effects on animal, human health, and the environment. PAHs are considered persistent compounds and can be bioaccumulated in sediments and aquatic biota. Determining PAHs in animals...
Article
Fluorescence spectroscopy with chemometric tools was used to check the milk authentication against the fraudulent addition of whey. Different commercial kinds of milk were adulterated with whey at five different levels. The fluorescence spectra of the adulterated samples showed different emission profiles when excited at the wavelength associated w...
Article
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Salmonella bacteria is a foodborne pathogen found mainly in food products causing severe symptoms in the individual, such as diarrhea, fever, and abdominal cramps after consuming the infected food, which can be fatal in some severe cases. Rapid and selective methods to detect Salmonella bacteria can prevent outbreaks when ingesting contaminated foo...
Article
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Metals, many of which are potentially toxic, are present in the aquatic environment originated from both natural and anthropogenic sources. In these ecosystems, these elements are mostly deposited in the sediment, followed by water dissolution, potentially contaminating resident biota. Among several aquatic animals, crustaceans are considered excel...
Article
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This study aimed to investigate Brazilian consumers’ perception concerning foods processed by ultraviolet (UV) radiation and ultrasound (US) and define consumer segments considering their socioeconomic characteristics and eating habits towards industrialized products through free word association tasks answered by 1004 participants via an online pl...
Article
In this study, we aimed to develop chitosan-based oleogels via crosslinking with vanillin using an emulsion-templated approach to allow the physical trapping of oil in the chitosan matrix. The role of Tween®60 to modulate the gelled network strength and the use of oleogels as a shortening substitute in cookies was also investigated. Four oleogels w...
Article
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Coronavidae viruses, such as SARS-CoV, SARS-CoV-2, and MERS-CoV, cause severe lower respiratory tract infection, acute respiratory distress syndrome and extrapulmonary manifestations, such as diarrhea and fever, eventually leading to death. Fast, accurate, reproductible, and cost-effective SARS-CoV-2 identification can be achieved employing nano-bi...
Article
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Background: Polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants routinely detected in aquatic ecosystems. It is, therefore, necessary to assess the link between deleterious marine biota PAH effects, especially in commercialized and consumed animals, environmental health status, and potential human health risks originating from the co...
Article
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Background Essential oils have been investigated for their potential application as a natural ingredient in food preservation. However, the low solubility in the aqueous phase, high volatility, and low long-term stability are limiting factors for its use as a natural preservative to replace traditionally used preservatives. With the advancement of...
Article
Watermelon is an l-citrulline-rich fruit that has been used as a supplement to increase l-arginine in plasma, which in turn plays a critical role in the synthesis of nitric oxide, a molecule that regulates vascular tone. Watermelon rind, similar to its pulp, presents a high l-citrulline content, yet a lower concentration of sugar, which would be mo...
Article
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PurposeAging is typically accompanied by risk for cardiovascular disease (CVD), which both are associated with reduced muscle oxygen saturation (SmO2) during exercise recovery. However, the apart impact of aging and CVD risk factors on muscle reoxygenation parameters during exercise recovery have not been addressed yet.Methods Twenty healthy young...
Article
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Texture profile analysis (TPA) is widely used to evaluate instrumental texture of fish fillets. However, different TPA setting conditions are the main limiting factor for its use as an official method of quality monitoring. Therefore, this study aimed to describe how texturometer settings affect the primary instrumental texture properties of Nile t...
Article
Exploratory data analysis was used to evaluate the influence of NaCl concentration on the relation between endogenous microbiota (mesophilic aerobic bacteria, psychrotrophic bacteria, lactic acid bacteria, Enterobacteriaceae and Staphylococcus spp.) and biogenic amines (BAs) (histamine, tyramine, putrescine, cadaverine and spermidine) content in Br...
Article
Brazil annually produces around 43 million tons of fruits and vegetables. Therefore, large amounts of pesticides are needed to grow these foods. The use of unauthorized or indiscriminate pesticides can lead to the adherence of residues of these compounds to the product in a concentration above the maximum residue limit (MRL). Pesticide residues (PR...
Article
Introduction Obesity-related metabolic diseases occur as a result of disruptions in white adipose tissue (WAT) plasticity, especially through visceral fat accumulation and adipocyte hypertrophy. This study aimed to evaluate the impact of renin–angiotensin system (RAS) and bradykinin receptors modulation by enalapril treatment and/or exercise traini...
Article
The use of skim milk is a strategy to increase goat milk yogurt acceptability. However, it can negatively affect yogurt rheology because fat plays a vital role in dairy structural integrity. Thus, this study aimed to investigate the effects of fat replacers on the rheological, physical, and sensory parameters of low-fat cupuassu goat milk yogurts d...
Article
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Natural antimicrobials (NA) have stood out in the last decade due to the growing demand for reducing chemical preservatives in food. Once solubility, stability, and changes in sensory attributes could limit their applications in foods, several studies were published suggesting micro-/nanoencapsulation to overcome such challenges. Thus, for our syst...
Article
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Infant formulas, designed to provide similar nutritional composition and performance to human milk, are recommended when breastfeeding is not enough to provide for the nutritional needs of children under 12 months of age. In this context, the present study aimed to assess the protein quality and essential amino acid content of both starting (phase...
Article
Background Sodium chloride (NaCl) is an essential food additive used for preservation/flavor enhancement. Food processing with NaCl has higher sodium contents, raising the concern between the excess of dietary sodium as a risk factor for several health problems. Thus, there is a growing demand for alternatives to reduce sodium in processed foods....
Article
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Rapid and selective methods for detecting and diagnosing Influenza viruses can be useful to prevent a possible new pandemic. Biosensors are highly sensitive and can be a simpler, faster, and cheaper method for rapid detection of Influenza being an alternative to conventional ELISA and PCR techniques. This study systematically searched and overviewe...
Article
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Despite evidence of health benefits from kefir administration, a systematic review with meta-analysis on bioactive compounds associated with these benefits is still absent in the literature. Kefir is fermented milk resulting from the metabolism of a complex microbiota in symbiosis. Recent researches have investigated the bioactive compounds respons...
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Coronaviruses disease (COVID-19) vaccines have emerged worldwide to control this illness, albeit they cannot guarantee full effectiveness. Polyphenols possess antioxidant, anti-inflammatory, and antiviral properties, all of which may be effective against COVID-19 symptoms. Since polyphenols exhibit low bioavailability, polyphenols nano-formulation...