Carlo V Caballero-Uribe

Universidad del Norte | Uninorte · Department of Medicine

A consensus meeting of representatives of 16 Latin American and Caribbean countries and the REAL-PANLAR group met in the city of Bogota to provide recommendations for improving quality of care of patients with rheumatoid arthritis (RA) in Latin America, defining a minimum standards of care and the concept of center of excellence in RA. Twenty-two r...

At the end of 2013, the Pan American Health Organization issued an epidemiological alert due to the detection of the first local cases of Chikungunya in the Americas. By August 2015, autochthonous transmissions were detected in 33 countries and territories of the Americas. Latin America has reported nearly one million cases; only Colombia has issue...

Introduction Biologics have improved the treatment of rheumatic diseases, resulting in better outcomes. However, their high cost limits access for many patients in both North America and Latin America. Following patent expiration for biologicals, the availability of biosimilars, which typically are less expensive due to lower development costs, pro...

Con este proyecto intentamos cubrir algunas brechas en la difusión del conocimiento científico, como la falta de impacto de las publicación fuera de los escenarios exclusivamente académicos, evitar la dependencia exclusiva de las citaciones e impulsar unas métricas que sean adecuadas para el siglo XXI.

Notwithstanding the wealth of literature on COVID-19, studies focusing on young adults with autoimmune diseases (AD) are lacking. To determine early (within 7 days) and late (after 7 days) anti-SARS-CoV-2 vaccine-related adverse events (AEs), post-vaccine disease flares, COVID-19 severity and breakthrough infections (B-INFs) in young people with rh...

Background COVID-19 has been suggested as a possible trigger of disease flares in patients with rheumatoid arthritis (RA). However, factors associated with disease flares remain unknown. Objectives This study aimed to identify factors associated with disease flares in patients with RA following COVID-19. Methods We selected patients with RA from...

Background Patients with autoimmune diseases (AD) are often at risk of severe COVID manifestations and post COVID syndrome (PCS). Pregnant and breastfeeding (PB) women with AD are an even more vulnerable population, though little is known about the prevalence and characteristics of PCS. Objectives We explored the frequency and characteristics of P...

Background Psychosocial wellbeing significantly contributes to the overall health experiences of individuals with systemic lupus erythematosus (SLE). Mental health is often influenced by the intricate interplay between multifaceted factors, including the impact of disease on quality of life, pain, fatigue, drug-related side effects, and disease-spe...

Background Idiopathic inflammatory myopathies (IIM) encompass a group of disorders characterized by muscle inflammation, weakness, and varying levels of systemic involvement. These conditions profoundly impact patients’ quality of life (QoL) due to their chronic nature, physical impairments, and accompanying mental health challenges. Recent literat...

Background Despite the overall safety and efficacy of COVID‐19 vaccinations, rare cases of systemic autoimmune diseases (SAIDs) have been reported post‐vaccination. This study used a global survey to analyze SAIDs in susceptible individuals' post‐vaccination. Methods A cross‐sectional study was conducted among participants with self‐reported new‐o...

Objective The management of systemic lupus erythematosus (SLE) relies on accurately evaluating disease activity. However discordance between physician and patient perceptions of disease activity are frequently observed. With the increasing prevalence of virtual consultations, understanding factors contributing to this discordance in patient perceiv...

Objective Globally, there is an absence of standardised protocols for the treatment of SLE. This study aimed to conduct a worldwide evaluation of treatment, including the use of steroids, conventional DMARDs and biologic agents in SLE. Additionally, we sought to explore the impact of the Human Development Index (HDI) on regional variations in thera...

Objective This study aimed to investigate the prevalence of comorbidity, multimorbidity and mental health disorders in patients with systemic lupus erythematous (SLE) and the association with patient reported physical and mental outcome scores (PROMIS). Methods Data from the COVAD survey was utilised for analysis. Comorbidities including cardiovas...

COVID-19 has been suggested as a possible trigger of disease flares in patients with rheumatoid arthritis (RA). However, factors associated with disease flares remain unknown. This study aimed to identify factors associated with breakthrough infection (BIs) and disease flares in patients with RA following COVID-19. We analysed data from RA patients...

Objectives To investigate health-related quality of life in patients with idiopathic inflammatory myopathies (IIMs) compared with those with non-IIM autoimmune rheumatic diseases (AIRDs), non-rheumatic autoimmune diseases (nrAIDs), and without autoimmune diseases (controls), using Patient-Reported Outcome Measurement Information System (PROMIS) ins...

Objectives To explore prevalence, characteristics and risk factors of COVID-19 breakthrough infections (BIs) in idiopathic inflammatory myopathies (IIM) using data from the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. Methods A validated patient self-reporting e-survey was circulated by the COVAD study group to collect data on COVID-...

To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on pa...

Background: The safety profile of COVID-19 vaccination is well documented, but hesitancy among people with immune-mediated inflammatory diseases, often immunocompromised, remains high, partially due to a scarcity of data on safety over a longer term. We herein aimed to assess delayed adverse events (DAEs) occurring >7 days after COVID-19 vaccinati...

Vaccine hesitancy poses a significant global health challenge, fueled by misinformation and anti-vaccination campaigns on social media platforms (SMPs). This study examines the influence of social media on coronavirus disease 2019 (COVID-19) and non-COVID-19 vaccination in Asia during the peri-pandemic period. Through a comprehensive analysis of av...

Background Although many studies have been conducted within COVID-19, there are still unanswered questions regarding breakthrough infections (BTIs), particularly in patients with systemic lupus erythematosus (SLE). We aimed to determine the occurrence of breakthrough COVID-19 infections in patients with SLE versus other autoimmune rheumatic disease...

Objectives: We investigated COVID-19 vaccine safety in pregnant and breastfeeding women with autoimmune diseases (AID) in the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. Methods: Delayed-onset (>7 days) vaccine-related adverse events (AE), disease flares (DF), and AID-related treatment modifications were analyzed upon diagnosis of...

Limited evidence on long-term COVID-19 vaccine safety in patients with idiopathic inflammatory myopathies (IIMs) continues to contribute to vaccine hesitancy. We studied delayed-onset vaccine adverse events (AEs) in patients with IIMs, other systemic autoimmune and inflammatory disorders (SAIDs), and healthy controls (HCs), using data from the seco...

Background Comorbidities have a profound impact on the QoL of patients living with autoimmune rheumatic diseases (AIRDs). Unfortunately, global data on the burden of comorbidities and its impact on health outcomes in this vulnerable group is scarce. Objectives We studied the prevalence, distribution and clustering of comorbidities and multimorbidi...

Background Although many studies have been conducted on COVID-19 in recent years, there are still unanswered questions regarding breakthrough infections (BTIs), particularly in patients with systemic lupus erythematosus (SLE). Objectives This study aimed to determine the occurrence of breakthrough COVID-19 infections in patients with SLE versus ot...

Background Rheumatoid arthritis (RA) and spondyloarthritis, including either Psoriatic Arthritis (PsA) and Ankylosing Spondylitis (AS), are some of the most diagnosed autoimmune rheumatic diseases (AIRDs) in rheumatologists’ routine clinical practice [1]. Understanding patients’ health and functional status is crucial to provide personalized manage...

Background Post COVID-19 syndrome (PCS) is an emerging cause of morbidity and poor quality of life in COVID-19 survivors [1, 2]. Objectives We aimed to assess the prevalence, risk factors, outcomes, and association with disease flares of PCS in patients with autoimmune rheumatic diseases (AIRDs) and non-rheumatic autoimmune diseases (nrAIDs), both...

Background Notwithstanding the wealth of literature on COVID-19, studies focusing on young people with autoimmune diseases (ADs) are lacking. Despite their younger age, they may have been exposed to immunosuppressants (IS) for longer than older adults, particularly if diagnosed at pediatric age. Objectives To determine early (within 7 days) and la...

Background Limited data on the delayed onset effects of COVID-19 vaccination in patients with idiopathic inflammatory myopathies (IIMs) continues to be a significant cause of hesitancy in this vulnerable group. Objectives To analyze the delayed onset adverse events (ADEs) of COVID-19 vaccination in patients with IIMs, other systemic autoimmune and...

Background Regional disparities in the management of systemic lupus erythematosus (SLE) are frequently described. Governance, funding, logistic barriers, and physician choice may be important determinants though scarce data from underrepresented regions limits our understanding. Objectives To evaluate global patterns in treatment of SLE and identi...

Background Systemic lupus erythematosus (SLE) can result in impaired daily physical function through various mechanisms including active disease, chronic damage, and mental health symptoms that are common in the disease. However, the key drivers of reduced physical function are poorly understood, and no large-scale global studies investigating this...

Background Viral infections are known triggers of disease flares in idiopathic inflammatory myopathies (IIMs). Reports of post-COVID-19 flares of IIMs have raised suspicion of a possible role of SARS-COV-2 in their onset [1,2]. However, despite rising flare rates in this vulnerable patient group during the pandemic, the risk factors for post-COVID-...

Background Prevalence of comorbidities and their impact on health outcomes in Idiopathic inflammatory myopathies (IIMs) is limited. Objectives This study aimed to explore the prevalence of multimorbidity in patients with IIMs, other autoimmune rheumatic diseases (AIRDs) and Healthy controls (HCs). We further explore the impact of comorbidities on...

Objectives: Disease flares in the post COVID-19 vaccination period represent a prominent concern, though risk factors are poorly understood. We studied these flares among patients with idiopathic inflammatory myopathies (IIMs) and other autoimmune rheumatic diseases (AIRDs). Methods: The COVAD-1 and -2 global surveys were circulated in early 202...

Dear Editor, Viral infections are known triggers of disease flares in idiopathic inflammatory myopathies (IIMs). Reports of post-COVID-19 exacerbation of IIMs suggest a possible role for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in precipitating IIM disease flares [1]. Recently, analysis of patients with pre-pandemic adult-onset...

Objective: Flares of autoimmune rheumatic disease (AIRDs) following COVID-19 vaccination are an outstanding concern in vaccine-hesitant individuals. Therefore, we investigated the incidence, predictors and patterns of flares following vaccination in individuals living with AIRDs using global COVID-19 Vaccination in Autoimmune Diseases (COVAD) surv...

Objective: COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs), however hesitancy continues to persist among these patients.Therefore, we studied the prevalence, predictors, and reasons for hesitancy in patients with IIMs, other AIRDs, non-rheuma...

Objective COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs), however hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors, and reasons for hesitancy in patients with IIMs, other AIRDs, non-rheumat...

Las publicaciones científicas se han convertido en el vehículo preferido para dar a conocer los avances en el campo de la ciencia. En las últimas décadas ocurrieron cambios importantes relacionados con la difusión del conocimiento científico y, además, surgieron con fuerza los movimientos del acceso abierto y lo que se ha denominado ciencia abierta...

As publicações científicas tornaram-se o veículo preferencial para divulgar os avanços no campo da ciência. Nas últimas décadas, ocorreram mudanças importantes relacionadas à disseminação do conhecimento científico e, além disso, surgiram com força os movimentos de acesso aberto e o que tem sido chamado de ciência aberta. Da mesma forma, estas muda...

Scientific publications have become the preferred vehicle to announce advances made in the field of knowledge. In recent decades, the distribution of scientific knowledge has undergone important changes aided by the strong emergence of the Open Access and the so-called open science movements. These changes have brought about a conceptual modificati...

Editor's note: The note on Archibald Edward Garrod is the final entry of the initial series of History of Rheumatology with characters spanning the 17th century (Sydenham), 18th century (Heberden), 19th century (Osler and Garrod Sr.), and early 20th century (Garrod Jr.), constituting the legacy for Western rheumatology of what some have called the...

Dear Editor, Patients with idiopathic inflammatory myopathies (IIMs) represent a high-risk group for adverse pregnancy outcomes (APOs), and post COVID-19 vaccination disease flares have been speculated. However, data on vaccine-associated adverse events (ADEs) in the antenatal period and APOs in this vulnerable group are virtually non-existent, lim...

Estamos comemorando dois anos do lançamento oficial da Global Rheumatology, uma nova revista científica da PANLAR. Neste período, a nascente publicação consolidou a sua política editorial com características diferenciadas que atendem às necessidades de promoção e difusão do conhecimento da comunidade reumatológica mundial e, em especial, da América...

Estamos cumpliendo dos años de haber lanzado oficialmente Global Rheumatology, una nueva revista científica para PANLAR. Durante este tiempo, la naciente publicación ha consolidado su política editorial con unas características diferenciales que atienden las necesidades de promoción y difusión del conocimiento de la comunidad reumatológica mundial,...

We are celebrating two years of officially launching Global Rheumatology, the new scientific journal for PANLAR. During this time, the emerging publication has consolidated its editorial policy with differential characteristics that meet the needs of promotion and communication of knowledge of the rheumatology community worldwide, especially in Lat...

Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently appro...

No final do novembro passado, a UNESCO adotou o primeiro marco internacional sobre Ciência Aberta. Este documento foi assinado por todos os 193 países presentes na 40ª Conferência Geral desta organização que busca tornar as descobertas científicas mais transparentes e acessíveis.

La Unesco adoptó a finales de noviembre pasado el primer marco internacional sobre Ciencia Abierta. Este documento fue firmado por la totalidad de los 193 países presentes en la 40ta Conferencia General del organismo que busca hacer más transparentes y accesibles los hallazgos científicos.

At the end of last November, UNESCO adopted the first international framework on Open Science. This document was signed by all 193 countries present at the 40th General Conference of the organization, which aims to improve the transparency and accessibility of scientific findings

As Doenças reumáticas e musculoesqueléticas (DsRM por sua sigla em português) são patologias crônicas de alta morbidade com grande impacto na qualidade de vida,que geram incapacidades e aumentam os custos do atendimento. Na América Latina, existem várias barreiras para o atendimento ao paciente. O objetivo do estudo foi identificar as necessidades...

Rheumatic and musculoskeletal diseases (RMDs for its acronym in English), are chronic pathologies of high morbidity with a great impact in quality of life, which generate disability and increase the costs of care. In Latin America there are multiple barriers to patient care. The objective of the study was to identify the care needs and difficulties...

Nesta Entrevista con la Historia falaremos com o Alfred B. Garrod, que fez importantes contribuições para o estudo da gota e da nomenclatura das doenças reumáticas, introduzindo o termo artrite reumatóide hoje utilizado, entre outras contribuições para a medicina, sendo um dos precursores da reumatologia moderna.

In this Interview with History we will talk with Alfred B. Garrod, a person who made important contributions in the study of gout and the nomenclature of rheumatic diseases. He was the person who introduced the term rheumatoid arthritis used today, among other contributions to medicine. Garrod is one of the precursors of modern rheumatology.

El Educational Needs Assessment Tool-versión española (SpENAT) es un cuestionario que evalúa las necesidades educativas (NE) de pacientes. Este estudio estableció las fuentes de información que los pacientes utilizan y evalúa las NE de pacientes con OA de rodilla utilizando el SpENAT.

The Spanish version of the Educational Needs Assessment Tool (SpENAT), is a self-completed questionnaire that assesses the educational needs (ENs) in osteoarthritis (OA) patients, with the purpose of providing tailored and patient-centered information. This study established the sources of information that patients use and to evaluate the ENs of pa...

En este videoblog hablamos de los retos y la importancia de las publicaciones científicas, así como la identidad panamericana de GR by PANLAR para llevar la investigación de nuestro continente al mundo.

Resumen en Español Las métricas son herramientas que permiten evaluar el impacto de los productos de investigación. Se clasifican en tradicionales y no tradicionales, las primeras enfocadas en el número de citas, mientras que las ultimas se enfocan en el análisis de tendencias de las publicaciones o trazabilidad digital. Las métricas tradicionales...

La vacunación contra el covid-19 es la respuesta más importante que está dando la ciencia a la amenaza global que ha representado la pandemia. En la primera parte revisamos la seguridad y eficacia de las vacunas. Esta segunda parte incluye las consideraciones especiales en pacientes con enfermedades reumáticas autoinmunes teniendo en cuenta la nece...

La vacunación contra el covid-19 es la respuesta más importante que está dando la ciencia a la amenaza global que ha representado la pandemia. Este artículo especial de vacunación y enfermedades reumáticas tiene dos partes. En la primera parte se revisarán los aspectos relevantes de la seguridad y eficacia de las vacunas y en la segunda parte las c...

En esta nueva entrevista con la historia avanzamos a finales del siglo XIX e inicios del siglo XX para revisar los aportes de William Osler el padre de la medicina moderna occidental y un pionero de la reumatología.

Abstract Background/Objective The Latin American population living with lupus lacks reliable and culturally competent health education resources. We describe a Spanish and Portuguese online program to educate Latin American people about lupus. Methods An extensive network of Latin American stakeholders participated in the program design, impleme...

"Las enfermedades reumáticas y musculoesqueléticas (ERyMEs por sus siglas en español), son patologías crónicas de alta morbilidad con gran impacto en la calidad de vida, que generan discapacidad e incremento en los costos de atención médica. En latinoamérica hay múltiples barreras frente al cuidado del paciente. El objetivo de este estudio fue el i...

Background/objective: The Latin American population living with lupus lacks reliable and culturally competent health education resources. We describe a Spanish and Portuguese online program to educate Latin American people about lupus. Methods: An extensive network of Latin American stakeholders participated in the program design, implementation...

Las entrevistas con la historia son piezas biográficas de personajes que se han constituido como la columna vertebral de la especialidad que conocemos como Reumatología. Están basadas en textos escritos por el Dr. Antonio Iglesias, preparados por nuestra periodista Estefanía Fajardo de la Espriella en forma de entrevistas ficticias que nos puedan b...

Background Rheumatic diseases are a reason for frequent consultation with primary care doctors. Unfortunately, there is a high percentage of misdiagnosis.Objective To design an algorithm to be used by primary care physicians to improve the diagnostic approach of the patient with joint pain, and thus improve the diagnostic capacity in four rheumatic...

Creemos que la divulgación a través del magazíne será un soporte fundamental para la revista científica y un complemento que a nuestro juicio es novedoso y diferencial en el mundo de las publicaciones científicas, pues permitirá conocer con detalle los aportes de la comunidad de científicos de PANLAR a la reumatología global y tener una mirada ampl...

The original version of this article, unfortunately, contained an error. The first and family name of Loreto Massardo was interchanged and is now presented correctly in this article.

Objectives To identify baseline predictors of remission and low disease activity (LDA) in early rheumatoid arthritis (RA) from the GLADAR (Grupo Latino Americano De estudio de la Artritis Reumatoide) cohort. Methods Patients with 1- and 2-year follow-up visits were included. Remission and LDA were defined by DAS28-ESR (< 2.6 and ≤ 3.2, respectivel...

The two co-authors of the mentioned above article were incorrect. The correct are authors should have been “P. A. Beltrán” instead of “P. A. B. Roa” and “J. F. Diaz-Coto” instead of “L. Diaz Soto”.

The Pan American League of Associations for Rheumatology (PANLAR) is an umbrella organization of rheumatology national societies in the Americas, encompassing 21 countries. Of those, 19 nations are located in Latin America and the Caribbean region.1 The aims of PANLAR are 2-fold: (1) stimulate and promote the study and research of rheumatic disease...

The Pan American League of Associations for Rheumatology (PANLAR) is an umbrella organization of rheumatology national societies in the Americas, encompassing 21 countries. Of those, 19 nations are located in Latin America and the Caribbean region.1 The aims of PANLAR are 2-fold: (1) stimulate and promote the study and research of rheumatic disease...

Background/objective: Although mortality rates related with chikungunya (CHIK) outbreaks in Latin America's (LA's) dengue-endemic rural and new urban regions are low, dealing with symptoms and sequelae can both produce a significant burden of disease and diminish quality of life-from many months to years-after the acute phase of the infection, wit...

Background/historical perspective: Availability of biologic disease-modifying antirheumatic drugs (bDMARDs) has improved clinical outcomes in rheumatoid arthritis, but it also increased the cost of treatment. Biosimilars, the regulated copies of biologic products, have a potential to reduce health care costs and expand access to treatment. However...

Background Although mortality rates related with Chikungunya (CHIK) outbreaks into Latin America’s endemic-dengue rural and new urban regions are low, dealing with symptoms and sequelae can produce both a significant burden of disease and diminish quality of life — from many months to years — after the acute phase of infection, with a significant i...

Objective: Textbooks are an important source to teach Medicine and Rheumatology. The aim of this work is to to identify Latin American books published on Rheumatology topics that could be considered textbooks to teach Rheumatology in the region Materials and Methods: An exhaustive search was made of panaméricanas publications in rheumatology, book...

Objective: Journals are an important source of scientific communication. We aim to analyze the impact of the international journals of Rheumatology with emphasis on those of the PANLAR region. Materials and Methods: A bibliometric study of Rheumatology journals worldwide, indexed in Web of Science (WoS) , Scopus and Google Scholar, was conducted. W...

On the 50th anniversary of PANLAR, Píndaro Martínez Elizondo referred to the history of the association as a “first entry”: “It’s a challenge as well as a call to all members to provide information that in the short term will allow us to know ourselves and our origins better”. He stated his openness to continuing a conversation begun by the then di...

Background: By 2015, the World Health Organization reported that 1% of the world population suffered from rheumatoid arthritis (RA) and in Latin America (LATAM) between 0.5% and 1%. Previously, in May 2014, a consensus meeting was held in Barranquilla, Colombia, where the Project for Implementation and Accreditation of Centers of Excellence (CoE)...

Los autores realizan un análisis sobre la situación actual de las revistas científicas colombianas, el impacto del nuevo modelo de clasificación de revistas científicas de Publindex-Colciencias, su relación con los principios del Manifiesto de Leiden. Hacen mención del uso de las nuevas tecnologías y redes sociales en la comunicación científica.

Los autores realizan un análisis sobre la situación actual de las revistas científicas colombianas, el impacto del nuevo modelo de clasificación de revistas científicas de Publindex-Colciencias, su relación con los principios del Manifiesto de Leiden. Hacen mención del uso de las nuevas tecnologías y redes sociales en la comunicación científica.

The use of social networks as educational platforms is continually growing through a combination of formal and informal methods. This paper describes the concept of digital health and the benefits and limitations of certain digital platforms, specifically those related to social media, and explains the rise of “informed patients” and a new digital...

Health education is fundamental in the management of RA patients. This study explored patient needs for educational material appropriate for RA patients in our region through a website. This study includes seven focus groups and semi-structured interviews across 4 countries (Argentina, Chile, Colombia, and Mexico) with 71 RA patients. Transcripts w...

The implementation of excellence centers in specific diseases has been gaining recognition in the field of health; specifically in rheumatoid arthritis, where the prognosis of the disease is related to an early diagnosis and a timely intervention, it is necessary that the provision of health services is developed in an environment of quality, oppor...