Carine Kunsevi- PostDoc Position at Stellenbosch University
Carine Kunsevi
- PostDoc Position at Stellenbosch University
About
5
Publications
612
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
25
Citations
Current institution
Publications
Publications (5)
Type 2 diabetes (T2D) increases susceptibility to tuberculosis (TB) with the underlying mechanisms remaining unknown. To determine whether immune dysfunction in the lung contributes to TB susceptibility, we obtained paired human alveolar macrophages (HAMs) and monocyte-derived macrophages (MDMs) from TB-exposed individuals with/without T2D. Upon in...
Background: Mycobacterium tuberculosis (M.tb), the causative bacterium of tuberculosis (TB), establishes residence and grows in human alveolar macrophages (AMs). Inter-individual variation in M.tb-human AM interactions can indicate TB risk and the efficacy of therapies and vaccines; however, we currently lack an understanding of the gene and protei...
Type 2 diabetes (T2D) is a prevalent risk factor for tuberculosis (TB), but most studies on TB-T2D have focused on TB patients, been limited to one community, and shown a variable impact of T2D on TB risk or treatment outcomes. We conducted a cross-sectional assessment of sociodemographic and metabolic factors in adult TB contacts with T2D (versus...
Antioxidants are compounds that easily donate an electron to become oxidized, while oxidants readily accept these electrons. An antioxidant thus slows down or prevents the oxidation of other molecules. Enzymes normally counteract these effects. Various trace elements are incorporated into the structure of enzymes and are the center of activity. In...
