Carin Basirun

Carin Basirun
University of Technology Sydney | UTS · School of Biomedical Engineering

Bachelor of Engineering

About

7
Publications
1,267
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83
Citations
Introduction
I'm a highly motivated biomedical engineering PhD candidate with a passion and a goal to bring science and innovation together to create solutions that make a difference. Working on developing an engineered heart-on-a-chip, a biologically relevant 3D cardiovascular model, by utilizing 3D bioprinting, microfluidics, and bioreactor technologies. Also using microgravity and space radiation as a tool to uncover the underlying mechanotransduction properties that lead to cardiovascular diseases.

Publications

Publications (7)
Article
Full-text available
The advancement of microgravity simulators is helping many researchers better understanding the impact of the mechanically unloaded space environment on cellular function and disfunction. However, performing microgravity experiments on Earth, using simulators such as the Random Positioning Machine, introduces some unique practical challenges, inclu...
Article
This cover image represents the bioconvergence between microfluidics, 3D bioprinting, lab-on-chip and microgravity technologies to develop a new approach towards the development and understanding of complex biological microenvironments including brain cancer which is described in this study. The emergence of space mechanobiology has demonstrated po...
Article
Full-text available
In recent years, there has been an increasing interest in space exploration, supported by the accelerated technological advancements in the field. This has led to a new potential environment that humans could be exposed to in the very near future, and therefore an increasing request to evaluate the impact this may have on our body, including health...
Article
Full-text available
Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors and urgently requires the development of new therapeutic strategies. In this study, an innovative hybrid in vitro vascularized GBM‐on‐a‐chip model is presented as a strategic integration of microfluidics and 3D bioprinting technologies. The system can recreate the co...
Article
Full-text available
Brillouin imaging (BI) has become a valuable tool for micromechanical material characterisation, thanks to extensive progress in instrumentation in the last few decades. This powerful technique is contactless and label-free, thus making it especially suitable for biomedical applications. Nonetheless, to fully harness the non-contact and non-destruc...
Preprint
Full-text available
Brillouin spectroscopy is a century-old technique that has recently received renewed interest, as modern instrumentation has transformed it into a powerful contactless and label-free probe of micromechanical properties for biomedical applications. In particular, to fully harness the non-contact and non-destructive nature of Brillouin imaging, there...

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