Canbolat Gürses

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Verified

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• PhD
• Assistant Professor at Inonu University

Bioadhesives are crucial in minimally invasive procedures but often lack biocompatibility, mechanical strength, and antimicrobial properties. Polyurethane-based adhesives, particularly UV-curable types, offer tunable properties and rapid curing. This study developed a polyurethane-acrylate adhesive system incorporating sericin and gentamicin to enh...

In this study, multifunctional wound and burn dressing material was developed to cover open wounds and protect them from external effects. Trimethylolpropane ethoxylate-170 (TMPE)-based polyurethane/polycaprolactone (PU/PCL) dressing materials were prepared with high biocompatibility and ordered nanofiber formation. Prepared PU/PCL dressing materia...

Immobilized enzymes have encountered two main challenges: Reduced enzyme activity compared to free enzymes and exhausted immobilized enzymes due to reusability. Herein, we suggested a promising activity enhancement strategy to overcome these challenges. The emission from upconversion nanoparticles (UCNPs) under near-infrared (NIR) excitation can in...

In this study, biocompatible, antibacterial and high mechanical strength polyurethane-based wound dressing materials were prepared by using the electrospinning technique. In addition, allantoin and gentamicin which will contribute to wound healing, were incorporated into these fiber materials. Polyurethane structures containing trimethylolpropane e...

New seven Au‐N‐heterocyclic carbene (NHC) complexes have been synthesized via transmetalation from Ag‐NHC complexes. NHC salts, Ag‐NHC, and Au‐NHC complexes were fully characterized by widely used spectroscopic techniques. The molecular and crystal structures of 3b and 3f Au‐NHC complexes were clarified through the single‐crystal X‐ray diffraction...

The present study aimed to determine the cytotoxicity of chromium(III) oxide micro particles (Cr2O3-Ps) in rainbow trout (Oncorhynchus mykiss) spermatozoa. Firstly, Cr2O3-Ps were synthesized and structurally characterized the surface, morphological for particle size and thermal properties. In addition, its structural and elemental purity was determ...

Antibacterial polyurethanes as wound-dressing material with high biocompatibility and thermal stability were developed from polyethylene glycol-200 (PEG200), 4,4′-methylenebis(cyclohexyl isocyanate) (HMDI) and β-cyclodextrin (βCD). βCD was preferred in this material because of providing biocompatibility and supporting the absorption/desorption char...

Today, polyurethanes are widely used in our daily lives from the textile industry to medical applications. In this study, we prepared a biocompatible and transparent coating from PEG containing linear polyurethanes including one type of saccharide (xylose, sucrose, or starch). For the characterization of the polyurethanes, FT-IR, TGA, DTA, DSC, and...

In our research, the antibacterial properties of tear which protect our eyes from many infections have been investigated by using Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus haemolyticus and Staphylococcus epidermidis bacteria. In addition, the antibacterial effect of creams in different formulations containing vaseline, also known as...

Hard or soft tissue adhesives have been presented as a promising candidate to replace traditional wound closure methods. A series of hard tissue bioadhesive formulations based on natural polymers have recently been designed and investigated in our laboratory. In current work, we produced an UV-curable polyurethane-acrylate formulations as a bioadhe...

Here, we present a study on the synthesis and biological properties of the ruthenium complexes having naphthyl substituted NHC ligands, which are of great importance for drug development studies. For this purpose, in our study, imidazolidine-functionalized Ru(II)NHC complexes containing naphthyl substitute group were synthesized and in vitro antica...

The present study aimed to determine the cytotoxicity of Chromium (III) oxide micro particles (Cr 2 O 3 -Ps) in rainbow trout ( Oncorhynchus mykiss ) spermatozoa. Firstly, Cr 2 O 3 -Ps were synthesized and structurally characterized the surface, morphological for particle size and thermal properties. In addition, its structural and elemental purity...

This study presents a more extensive report on the experimental and theoretical characterization of the Ce-doped hydroxyapatite (HAp) samples additionally doped with Pr at varying amounts. To achieve this goal, four Ce-containing (a constant amount of 0.35 at.%) HAps additionally doped with Pr at various amounts (0.35, 0.70, 1.05, and 1.40 at.%) we...

Researchers have recently focused on the advancement of new materials from biorenewable and sustainable sources because of great concerns about the environment, waste accumulation and destruction, and the inevitable depletion of fossil resources. Biorenewable materials have been extensively used as a matrix or reinforcement in many applications. In...

In the present study, coumarin‐bearing three pyridinium and three tetra‐alkyl ammonium salts were synthesized. The compounds were fully characterized by ¹H‐ and ¹³C‐NMR, LC/MS and IR spectroscopic methods and elemental analyses. The cytotoxic properties of all compounds were tested against human liver cancer (HepG2), human colorectal cancer (Caco‐2...

Five different samples of Sr-based Er-doped hydroxyapatites (HAps) in the dissimilar quantities like 0, 0.35,0.70, 1.05 and 1.40 at% were produced via a wet chemical process. The prepared samples were investigatedexperimentally by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray(EDX), Fourier transform inf...

In recent years, the preparation of metal complexes and the introduction of biologically active organometalic compounds are new strategies in drug development. For this purpose, generally N-heterocyclic pharmaceutical agents have been used as promising nuclei. Au-containing N-heterocyclic carbene (Au-NHC) derivatives are among the compounds used fo...

Recently, the medical applications of organoruthenium complexes have attention attracted to organometallic chemists and biochemists. In this study, 4-vinylbenzyl and 2-morpholinoethyl substituted (NHC)Ru(II)(η⁶-p-cymene) complexes were synthesized and in vitro DNA binding, cell cytotoxicity (anticancer activity) and genotoxicity properties were det...

A series of the morpholine‐liganded palladium(II) complexes (1a–e) bearing N‐heterocyclic carbene (NHC) functionalized by benzonitrile were synthesized. These complexes were synthesized from (NHC)Pd(II)(pyridine) complexes (PEPPSI) and morpholine. The new complexes were fully characterized by using 1H NMR, 13C NMR, Fourier‐transform infrared spectr...

In the present study, four palladium and four ruthenium complexes were synthesized with benzotriazole substituted N-heterocyclic carbene ligands. The structures of complexes were established by appropriate spectroscopic methods and elemental analyses. In addition, the crystal structure of a Pd–]NHC complex (1c) was reported. Anticancer, antimicrobi...

In this study, six [Ag(NHC)2]⁺[AgCl2]⁻ type silver complexes were synthesized by the reaction of corresponding carbene precursor and Ag2O. One [Ag(NHC)2]⁺NO3⁻ type complex was synthesized by the anion exchange reaction of corresponding silver–NHC and NaNO3. The synthesized complexes were characterized by ¹H NMR, ¹³C NMR and IR spectroscopic methods...

New benzimidazolium salts 1a-d having methylpyridine group on the side chain, have been synthesized and reacted with Ag2O to produce Ag(I)-N-heterocyclic carbene (NHC) complexes 2a-d. Ag(I)-N-heterocyclic carbene (NHC) complexes were used as a carben transfer agents to synthesize water-soluble ruthenium(II)-NHC complexes 4a-d. All synthesized compo...

The aim of this study was to characterize and investigate the effects of the Mobil Composition of Matter No. 41 (MCM‐41) concentrations (0.5, 1, 3, 5 and 10 wt%) on structural, thermal, wettability, water content, oxygen (O2) permeability and swelling properties as well as morphological characteristics of chitosan/polyvinylpyrrolidone/MCM‐41 (CH/PV...

Hybrid materials are composites consisting of organic and inorganic species connected each other with physical and chemical interactions at the nanometer or molecular level. In hybrid polymer composite materials, interactions of components in microscale dimensions lead to a more homogeneous material that either shows characteristics in between the...