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Citations since 2017
8 Research Items
July 2018 - June 2019
Children's Hospital of Los Angeles; University of Southern California
November 2017 - June 2018
University of Kentucky
- PostDoc Position
August 1998 - June 2002
Johns Hopkins University
Field of study
- Cellular Molecular Neuroscience
Introduction Cardiopulmonary resuscitation (CPR) in the shunted single-ventricle population is associated with poor outcomes. Interposed abdominal compression-cardiopulmonary resuscitation, or IAC-CPR, is an adjunct to standard CPR in which pressure is applied to the abdomen during the recoil phase of chest compressions. Methods A lumped parameter...
We previously showed that mice deficient in apoptosis signal-regulating kinase-1 (ASK1) were partially protected against ventilator-induced lung injury. Because ASK1 can promote both cell death and inflammation, we hypothesized that ASK1 activation regulates inflammasome-mediated inflammation. Mice deficient in ASK1 expression (ASK1-/-) exhibited s...
The role of cardiac macrophage inflammasomes in ischemia/reperfusion injury associated with cardiopulmonary bypass in congenital heart surgery