Calvin KleinUniversität Bern | UniBe · Department of Chemistry and Biochemistry
Calvin Klein
Bachelor of Science
About
3
Publications
168
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8
Citations
Citations since 2017
Introduction
Hi!
My name is Calvin Klein, and I am a biochemist at the University of Bern in the wonderful group of Francesca Paradisi. If you would like to know more about me and my research, check out my Website: https://ck-biochem.com
Skills and Expertise
Publications
Publications (3)
Four pharmaceutically relevant nucleoside analogues (5-fluoro-2′-deoxyuridine, 5-chloro-2′-deoxyuridine, 5-bromo-2′-deoxyuridine, and 5-iodo-2′-deoxyuridine) have been synthesized by using a novel thymidine phosphorylase from the halotolerant H. elongata (HeTP). Following enzyme immobilization on microbeads, the biocatalyst was implemented as a pac...
The mammalian cytosolic thioredoxin (Trx) system consists of Trx1 and its reductase, the NADPH-dependent seleno-enzyme TrxR1. These proteins function as electron donor for metabolic enzymes, for instance in DNA synthesis, and the redox regulation of numerous processes. In this work, we analysed the interactions between these two proteins. We propos...
