Çağdaş Oto

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• PhD
• Professor at Ankara University

Bioprinting, an advanced additive manufacturing technology, enables the fabrication of complex, viable three-dimensional (3D) tissues using bioinks composed of biomaterials and cells. This technology has transformative applications in regenerative medicine, drug screening, disease modeling, and biohybrid robotics. In particular, in situ bioprinting...

Purpose We aimed to characterize and further understand CSF circulation and outflow of rabbits. To our knowledge, there is no research on contrast material–enhanced MR cisternography ( CE ‐MRC) with T1 and T2 mapping in the rabbit model using a clinical 3‐T MR unit without a stereotaxic frame. Materials and Methods Twenty‐one rabbits were included...

Mg-based biodegradable metallic implants are gaining increased attraction for applications in orthopedics and dentistry. However, their current applications are hampered by their high rate of corrosion, degradation, and rapid release of ions and gas bubbles into the physiological medium. The aim of the present study is to investigate the osteogenic...

The aim of this study was to examine the preen gland (uropygial gland) of Denizli rooster, an endemic species for Turkey, both macroscopic and by magnetic resonance imaging and to present its histological formation. Five adult male subjects were used for this study. Although some of the findings of the preen gland in Denizli rooster were quite simi...

In this study, it was aimed to physically create skull models of large-sized animal sample horse, cattle and pig species used in veterinary anatomy education with three-dimensional printing technology and to determine the suitability of these models anatomically. The anatomical structures on the skull models obtained for this purpose were examined...

Neuroanatomy is widely regarded as one of the most complex subjects in veterinary education and clinical practice. Understanding the brain ventricles in particular can be quite challenging for learners. In addition to classical methods, three-dimensional (3D) printed models can provide an efficient learning process. This study aimed to assess the e...

Purpose: Using 3-dimensional (3D) printers, the creation of patient-specific models is possible before and after a therapeutic intervention. There are many articles about replicas for training and simulation of aneurysm clipping. However, no paper has focused on 3D replicas obtained from 3-tesla 3D time of flight (3D-TOF) MR angiography for intras...

z Amaç: Çalışmada, bilgisayarlı tomografi (BT) görüntüleri ile her bir servikal omurun üç boyutlu (3B) modellerini oluşturmak; manuel ve dijital ölçüm yön-temleri ile her servikal vertebranın morfometrik parametrelerini belirlemek ve iki yöntem arasındaki doğruluğu karşılaştırmak amaçlanmıştır. Gereç ve Yöntem: Morfometrik analizler için dört erkek...

The use of 3D printing technology in the field of medicine, which started with the millennium, continues to increase today. Depending on the technological developments in this field, the use of rapid prototyping technology in the field of veterinary medicine is becoming widespread with the development of 3D printers, increasing material variety, ch...

An esophageal stricture may develop during healing of a large esophageal perforation. When such a stricture occurs, mechanical dilatation is the treatment of choice. As in our case, if a cervical esophageal stricture and leakage are present together, the treatment becomes even more challenging. As a new treatment method, we made spherical ice globe...

Veterinary anatomy education has become a field where theoretical knowledge has dominated considerably in general. Due to the limited amount of educational material and the presence of different kinds of animals, practical education remains in the background. The study is to point out the three dimensional (3D) printing models of the digital skelet...

COVID-19 disease caused by the SARS-CoV-2 virus has had serious adverse effects globally in 2020 which are foreseen to extend in 2021, as well. The most important of these effects was exceeding the capacity of the healthcare infrastructures, and the related inability to meet the need for various medical equipment especially within the first months...

Biomolecule carrier structures have attracted substantial interest owing to their potential utilizations in the field of bone tissue engineering. In this study, MOF-embedded electrospun fiber scaffold for the controlled release of BMP-6 was developed for the first time, to enrich bone regeneration efficacy. The scaffolds were achieved by first, one...

The aim of the study was to estimate the volume values of the cranial cavity and nasal cavity structures and to compare the efficiency of manual segmentation of three-dimensional reconstruction and Cavalieri's principle (CP) methodologies. Materials and methods: Volume values of the cranial cavity, maxillary sinus (MS), dorsal conchal sinus (DCS),...

The usage of cadavers as training material for students and lecturers is limited due to disadvantages of the fixation solutions and methods. These disadvantages include the toxicity of chemicals that are used in fixative solutions in terms of human health, the alteration of properties in fresh tissues and ethical concerns of the fixation processes...

The purpose of the study was to scan the brain and related structures in sheep with high-resolution magnetic resonance imaging (MRI) and three-dimensional (3D) multiplanar reconstruction for defining the anatomical regions. Six adult sheep, three of six were male and three of six were female used as cadaver, were utilized in this research. Heads we...

This study was aimed at: 1) estimating the volume and the volume fraction values of brain ventricles, grey matter and white matter with the Cavalieri principle and 2) creating three-dimensional reconstruction models of the brain ventricles by using magnetic resonance imaging. The brain structures of dogs were scanned with a 3T magnetic resonance sy...

It is essential to demonstrate organs and their structures practically in anatomy education. Plastination is an anatomical technique that has been used to prepare biological specimens for educational purposes. it is a gradual process by replacement of fluids in biological tissues with reactive polymers such as silicone, epoxy or polyester resin. Th...

Background: The aim of the study was to estimate the volume values of the cranial cavity and nasal cavity structures and to compare the efficiency of manual segmentation of three-dimensional reconstruction and Cavalieri’s principle (CP) methodologies. Materials and methods: Volume values of the cranial cavity, maxillary sinus (MS), dorsal conchal s...

Additive manufacturing, also known as three-dimensional (3D) printing, is bringing the technological breakthrough in many areas, such as engineering, art, education, and medicine. Two separate themes are described in this study. The first theme is to present a graphical 3D modeling approach of different hyoid bones. The second theme involves making...

The number of patients who needs bone substitutes is increasing worldwide. The potential of 3D bioprinting to produce personalized bone grafts showed promising results during the past decade [1]. However, problems remain in the timely and mass production of these grafts including issues related to quality assurance and engineer-clinician coordinati...

The aim of this study was to estimate and compare volume fraction values of grey matter (substantia grisea) in the cervical enlargement (intumescentia cervicalis) using stereological methods for two different types of birds. Ten pairs of quails and chickens were included in this study as one of them is flying and the other one is flightless bird sp...

This study was carried out to investigate the structural properties of pecten oculi in the common barn owl (Tyto alba) by light and electron microscope. Fourteen eyeballs from seven owls were studied. The pecten oculi was located postero-anteriorly in the retina layer where the optic nerve enters the eye. The pecten oculi that was dark brown and pl...

Otolithic activity is very rapid in the avian body, due to the catabolic enzymes in cells and tissues after death. Otolysis is an undesirable condition for scientists focused on the preservation of tissues. In the post mortem period, tissue and organs should be preserved as soon as possible by various fixation methods. Among these methods, formalin...

2017. Is Kaiserling solution a convenient fixative for mammalian organ specimens? Evaluation of morphometric, colorimetric and volumetric properties. Bulg. J. Vet. Med., 20, Suppl. 1, 62-67. Fixative solutions used for the preparation of anatomical specimens as for education materials show a great variety. This variation derives from the different...

Purpose: To introduce a temperature sensor implant (TSI) that mimics an active implantable medical device (AIMD) for animal testing of MRI heating. Computer simulations and phantom experiments poorly represent potential temperature increases. Animal experiments could be a better model, but heating experiments conducted immediately after the surger...

Bu çalışmanın amacı köpek beyninin 3 boyutlu anatomisinin 3 tesla manyetik rezonans tarama görüntülerinin multiplanar rekonstruksiyonu aracılığıyla in situ olarak gösterilmesidir. Neurocranial yapıların anatomik detaylarının gösterilmesi için 9 adet yetişkin mesaticephalic ırk köpek kullanıldı. Bu amaçla T1 ve T2-ağırlıklı space sekans taramalarını...

In-vivo determination of the volume ratio of breast muscles among the first local laying hybrid chicken and its parents Rhode Island Red (RIR) and Barred Rock (BAR) by using magnetic resonance (MR) imaging technique with Cavalieri principle and comparing of these data between the three breeds were aimed in this study. Ten pair of 50 weeks old RIR,...

In the study, pleomorphic rhabdomyosarcoma was described in the oral cavity and the lungs in an old dog. After surgical treatment of oral tumor, the mass was recurred in oro-maxillar region and metastasis to the lungs. In microscopic examination, neoplastic cells had eosinophilic cytoplasm, their nuclei were large, round to oval, and vesicular. The...

The aim of this study was to determine the anatomical structures in carpal region with the routine T1, T2 weighted (W) and three-dimensional (3D) magnetic resonance (MR) sequences that are frequently being used for the diagnosis and the treatment of the wrist disorders and to indicate the efficacy of MR imaging (MRI) on the rabbit's carpal region w...

The aim of this study was to determine the anatomical structures in carpal region with the routine T1, T2 weighted (W) and three-dimensional (3D) magnetic resonance (MR) sequences that are frequently being used for the diagnosis and the treatment of the wrist disorders and to indicate the efficacy of MR imaging (MRI) on the rabbit's carpal region w...

Imaging studies conducted on the modern imaging techniques for birds are limited and probably insufficient for the clinicians. As in mammals, magnetic resonance (MR) imaging (MRI) can be used as a convenient method for the diagnosis and treatment of the avian diseases. In this study, the whole bodies of 2 male and 2 female chickens were imaged by a...

In this work, it is demonstrated that a dual-drive birdcage coil can be used to reduce the radiofrequency heating of metallic devices during magnetic resonance imaging. By controlling the excitation currents of the two channels of a birdcage coil, the radiofrequency current that is induced near the lead tip could be set to zero. To monitor the curr...

In this study, measurement of testis volume by stereology in Kivircik rams, Turkey's traditional sheep breed, was purposed. Right and left testes with epididymis were taken from a total of 42 Kivircik rams whose carcass weights were measured previously. Fifteen, 14, and 13 of them were 5, 6, and 7 months old, respectively. Weights and morphometric...

Determination of 3 Tesla MR imaging appearance of the brain and associated structures was the aim of this study. T1 and T2-weighted (W) and 3D reformatted images obtained from 6 adult pigs were used to define the cranioencephalic structures and anatomic details in three planes. Relevant structures were identified and labeled at each level. Especial...

Anatomy of the guttural pouches and their associated structures such as bones, muscles, salivary glands, vessels and nerves were examined in detail in 4 adult donkey heads by magnetic resonance imaging (MRI). The protocol was performed using a superconducting magnet operating at a field strenght of 1,5 Tesla in 5 mm thickness transversal sections i...

In this study incidentally detected renal aplasia in right kidney and compensatory hypertrophy in left kidney have been defined with the anatomical and pathological findings in a 2 years old male crossbred cat which had suffered from infirmity, vomiting, anorexia and depression. In macroscopic examination, it was observed that the left kidney was l...

In this study, 10 adult Turkish Spiny Mice (Acomys cilicicus) and 10 adult Cypnot Spiny Mice (Acomy nesiotes) were used. After the coloured latex injection, the morphological and morphometrical properties of the dissected vessels were determined. In both mice species, similar to rat and mice, it was seen that 3 main branches including brachiocephal...

Polioencephalomalacia was described in two senile male donkeys. Necropsy revealed necrosis and cavitations of irregular shape and depth, extending from the cortex into the inner brain, on the left cerebral hemisphere in the first case and the right cerebral hemisphere in the second case. Microscopic examination demonstrated the grey matter of the b...

In this morphometric study, the ciliary ring, ciliary processes and ciliary plicae which reside in the ciliary body, were examined in New Zealand Rabbit. Both sides of the eyeballs of 20 adult New Zealand Rabbits were used. The width of ciliary ring were measured with calibers using stereomicroscope. In counting, number of ciliary plicae was 301.07...

Although, a lot of researchers have investigated air sacs in several birds' species, there hasn't been any information about the long-legged buzzard's air sacs. This study aimed to observe the air sacs of mature long-legged buzzard. So the sacs of 5 adult birds were treated by takilon from methylmethacrylate group and colored-neoprene latex for pol...

In the present study, a total of 20 bulbus oculi of 10 New Zealand Rabbit from left and right sides was used. By the use of Leica M16 stereomicroscope course of vessels entering to bulbus oculi, formation of circulus vasculosus nervi optici and ramifying of vessels in the bulbus oculi were investigated. It was detected that vascularisation of bulbu...

In this paper schistosoma reflexum was reported with anatomical and pathological findings in a dog for the first time.

In this macro-anatomical research, the data was based on direct observations of 14 adult donkey brains 10 male and 4 female. The brains were fixed in 10% formalin solution and the investigation was focused on macroscopic descriptions of the brain surface and of dissected brainstem features. Sulci and gyri on the brain hemispheres had quite curly st...

zet: Bu çalışmada, hipertrofi gözlenen yetişkin bir sığır kalbinde, kongenital bir defekt olan kalıcı foramen ovale olgusu tanımlandı. Uygun şekilde diseksiyonu yapılan kalp, basis cordis bölgesinden açılarak defektin yeri ve pozisyonu saptandı. Digital kumpas ile morfometrik ölçümler yapıldı. Daha sonra lezyonlu bölgeden alınan örnekler rutin doku...

The heads of 6 adult donkeys used in applied anatomy lessons, which were preserved in formalin and which displayed no difference with regard to sex, constituted the study material. In donkeys, the glandula pinealis was determined to be a dark-coloured endocrine gland, either water-drop-shaped or fusiform in shape, situated just in front of both col...

In this case presentation, patent foramen ovale which is congenital heart defect was described in the hypertrophic heart of an adult cattle. The heart was dissected carefully from the basis cordis area and place and position of defect was determined. Measurements were obtained by the use of a digital caliber meter. Then, tissue samples taken from t...

Ozgel O., Dursun N., Oto C. Arteries that supply the brain and the formation of circulus arteriosus cerebri in donkeys Summary The study investigated the anatomy of the arteries of the brain in seven donkeys following intravascular injection of colored latex via the a. vertebralis and a. carotis communis. Arterial blood washed the brain via the bil...