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Introduction
Synthesis, modifications and biological activities of the synthetic and natural heterocyclic compounds. Synthetic, physical and biological methods of the research. Currently I work in the field of organometallic chemistry., ferrocene-alkaloid conjugates. Development of the new methods of cross-coupling, one-pot multicomponent reactions. Searching of effective preparations for agriculture and medicine.
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September 1987 - June 1992
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Publications (114)
The title compound, C15H16N2O2·H2O, was synthesized via the alkylation of 3-hydroxymethylidene-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one with n-propyl iodide in the presence of sodium hydroxide. The organic molecule and the water molecule both lie on a crystallographic mirror plane. In the crystal structure, intermolecular O—H⋯O and O—H⋯N...
Chemical modification of natural compounds and their synthetic analogues are a perspective direction for creation a new, high performance drugs with various pharmacological activities.
Among derivatives of alkaloids of the plants Peganum harmala and Mackinlaya subulata Philipson, and also their thiophene analogues an efficient biologically active c...
The title compound, C17H16N2O2S, was obtained by condensation of 2,3-dimethylthieno[2′,3′:4,5]pyrimidino[1,2-a]pyridin-4-one with furfural in the presence of sodium hydroxide. One of the methylene groups of the tetrahydropyrido ring is disordered over two positions in a 0.87 (1):0.13 (1) ratio. The thieno[2,3-d]pyrimidin-4-one unit and the fura...
Consecutive extraction of latex and natural rubber from the roots of rubber-bearing plants such as Taraxacum kok-saghyz (TKS), Scorzonera tau-saghyz (STS), and Scorzonera Uzbekistanica (SU) were carried out. Latex extraction was carried via two methods: Blender method and Flow method. The results of latex extraction were compared. Cultivated rubber...
α-Aryliden-6H(nitro)- and 6,8-dibromo-2,3-tetramethylen-3,4-dihydroquinazol-4-ones were synthesized by condensation of 6H(nitro)- and 6,8-dibromo-2,3-tetramethylen-3,4-dihydroquinazol-4-ones with aromatic aldehydes, furfurol, and of α-formyl-2,3-tetramethylen-3,4-dihydroquinazol-4-one with benzaldehyde and 4-nitrobenzaldehyde in glacial acetic acid...
9-Arylidene-6H(nitro)deoxyvasicinones were synthesized by reaction of 6H(nitro)deoxyvasicinones and aromatic aldehydes and furfurol in glacial acetic acid.
A method was developed to prepare a-methyl(benzyl)deoxyvasicinones by alkylation of a-hydroxy- methylidenedeoxyvasicinone. It has been shown that the reaction proceeds anomalously through a deformylation step.
-Piperazinylmethylenedeoxyvasicinones have been synthesized by the interaction of -hydroxymethylenedeoxyvasicinones with various N-substituted piperazines.