Burel R Goodin

Burel R Goodin
University of Alabama at Birmingham | UAB · Department of Psychology

PhD

About

184
Publications
16,502
Reads
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3,731
Citations
Citations since 2016
109 Research Items
3057 Citations
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20162017201820192020202120220100200300400500600
20162017201820192020202120220100200300400500600
Introduction
Additional affiliations
August 2012 - present
University of Alabama at Birmingham
Position
  • Professor (Assistant)
September 2010 - July 2012
University of Florida
Position
  • PostDoc Position
January 2007 - August 2009
Johns Hopkins University
Position
  • Research Assistant

Publications

Publications (184)
Article
Full-text available
Background The pathoanatomic cause of chronic low back pain (cLBP) cannot be identified for up to 90% of individuals. However, dysfunctional processing of endogenous nociceptive input, measured as conditioned pain modulation (CPM), has been associated with cLBP and may involve changes in neuronal gene expression. Epigenetic-induced changes such as...
Article
Full-text available
Purpose of Review Antiretroviral therapy has significantly reduced morbidity and mortality in people with HIV. Despite being virally suppressed, sleep disturbances, chronic pain, and neurocognitive impairments persist which can negatively impact quality of life for people with HIV. This article presents relevant literature related to sleep disturba...
Article
The tendency to ruminate, magnify, and experience helplessness in the face of pain — known as pain catastrophizing — is a strong predictor of pain outcomes and is associated with adversity. The ability to maintain functioning despite adversity — referred to as resilience — also influences pain outcomes. Understanding the extent to which pain catast...
Article
Sleep disorders are prevalent among college students and are associated with poor academic performance. Few studies have included a clinical interview to comprehensively assess sleep disorder diagnostic criteria or assessed academic functioning (e.g., class attendance). College students (n = 277) were recruited to complete sleep questionnaires, a s...
Chapter
One clinically useful collection of tools for measuring the pain experiences of patients with chronic pain conditions is referred to as quantitative sensory testing (QST). QST includes an array of non-invasive procedures that quantify human pain perception during the administration of standardized noxious stimuli with predetermined physical propert...
Article
Full-text available
Disability prevention and preservation of independence is crucial for successful aging of older adults. To date, relatively little is known regarding disparities in independent aging in a disadvantaged older adult population despite widely recognized health disparities reported in other populations and disciplines. In the U.S., the Southeastern reg...
Article
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Extant literature posits that humans experience two types of threat: physical threat and social threat. While describing pain as “physical” or “social” can be helpful for understanding pain origins (i.e., broken bone versus lost relationship), this dichotomy is largely artificial and not particularly helpful for understanding how the human brain ex...
Article
PURPOSE Stigma surrounding prescription opioids, or opioid stigma, is increasingly recognized as a barrier to effective and guideline-concordant cancer pain management. Patients with advanced cancer report high rates of pain and prescription opioid exposure, yet little is known about how opioid stigma may manifest in this population. METHODS We co...
Article
Emerging literature suggests that non-specific chronic low back pain (cLBP) is linked with elevated serum levels of pro-inflammatory biomarkers. Additionally, evidence suggests that socioeconomic status may also have an impact on levels of inflammation, specifically at the neighborhood level. However, there is little information about how levels of...
Article
People with HIV (PWH) appear to be at high risk for the experience of recurring pain symptoms throughout their lifetimes. There is also evidence to suggest a high prevalence of insomnia and sleep difficulties in PWH. Insomnia may lead to exaggerated pain states in PWH such as hyperalgesia, which refers to the phenomenon of heightened sensitivity to...
Article
Emerging literature suggests that experiences of discrimination negatively influence health and well-being. It is unfortunately common for people living with HIV (PLWH) to be stigmatized and discriminated against because of their HIV status and other marginalized identities (e.g., ethnicity/race, sexual identity and orientation). To date, little re...
Article
Findings from a multi-site study conducted by our research team previously revealed that non-Hispanic Black (NHB) adults with high chronic pain stage have thinner temporal cortex relative to their non-Hispanic White (NHW) counterparts with knee pain. Groups differ on a number of neurobiologically relevant socio/environmental factors. Mounting evide...
Article
Prolonged postoperative opioid use (PPOU) is considered an unfavorable post-surgical outcome. Demographic, clinical, and psychosocial factors have been associated with PPOU, but methods to prospectively identify patients at increased risk are lacking. We sought to determine whether individual or a combination of several psychological factors could...
Article
Knee osteoarthritis (OA) is a common progressive joint disease with increasing prevalence. There are inconsistent findings on the concordance between radiograph derived Kellgren-Lawrence (KL) scores and pain measures. We have previously reported that dispositional traits predict sensory sensitivity and psychosocial functioning. This study aims to d...
Article
Chronic low back pain (cLBP) is the second leading cause of disability in the United States, and disproportionately burdens Non-Hispanic Black (NHB) individuals compared to Non-Hispanic White (NHW) individuals. However, its biological underpinnings are poorly understood. The aim of this study was to investigate differences in basal inflammatory cyt...
Article
Chronic low back pain (cLBP) is one of the leading causes of pain for millions of Americans. Recent growing literature suggests that individuals with cLBP may have elevated symptoms of depression. Optimism and pessimism are aspects of human personality related to generalized outcome expectancies for the future. Both are also associated with physica...
Article
Individuals with painful knee osteoarthritis (OA) frequently report poor sleep quality. Neighborhood disadvantage has been shown to be associated with poor sleep quality and detriments to physical health outcomes. The overall aim of this study was to elucidate further the relationships among neighborhood disadvantage, physical function, and sleep q...
Article
Considerable evidence demonstrates that radiographic findings (e.g., osteophytes) are only modestly associated with the severity of knee pain, suggesting that other biopsychosocial factors likely influence symptom severity. Multiple psychological factors have been linked to worse health outcomes in people with chronic knee pain; however, it remains...
Article
Chronic pain contributes to allostatic load (AL). Individuals with protective psychosocial and biobehavioral factors report lower levels of clinical pain. We have previously shown a relationship between a resilience index, telomere length, and brain structure. This study aims to assess the relationships between AL, a resilience index, and clinical...
Article
Chronic low back pain (CLBP) is one of the leading causes of pain and disability in adults in the United States and disproportionately burdens non-Hispanic Black (NHB) individuals and females. Approximately 90% of CLBP cases are of unknown cause, and it is imperative that potential causes be explored. It has been reported that diet quality can infl...
Article
Background: Disparities in trauma outcomes and care are well established for adults, but the extent to which similar disparities are observed in pediatric trauma patients requires further investigation. The objective of this study was to evaluate the unique contributions of social determinants (race, gender, insurance status, community distress, r...
Article
Chronic pain is a significant public health problem, and the prevalence and societal impact continues to worsen annually. Multiple cognitive and emotional factors are known to modulate pain, including pain catastrophizing, which contributes to pain facilitation and is associated with altered resting-state functional connectivity in pain-related cor...
Article
Full-text available
Compared to Non-Hispanic Whites (NHWs), individuals who self-identify as Non-Hispanic Blacks (NHBs) in the United States experience more severe and disabling chronic low back pain (cLBP). We hypothesized that differences in DNA methylation (DNAm) play a role in racial disparities in cLBP. Purpose: To determine the relationship between DNAm levels...
Article
Full-text available
Racism is an established health determinant across the world. In this 3-part series, we argue that a disregard of how racism manifests in pain research practices perpetuates pain inequities and slows the progression of the field. Our goal in part-1 is to provide a historical and theoretical background of racism as a foundation for understanding how...
Article
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This third paper in the “Confronting Racism in All Forms of Pain Research” series discusses adopting an antiracism framework across all pain research disciplines and highlights the significant benefits of doing so. We build upon the previous call to action and the proposed reframing of study designs articulated in the other papers in the series and...
Article
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This second paper in a three-part series on antiracism in pain research across the translational spectrum focuses on study design factors. Although objectivity is a cornerstone value of science, subjectivity is embedded in every step of the research process as investigators make choices about who they collaborate with, which research questions they...
Article
Full-text available
Chronic low back pain (cLBP) is the most common reason for individual suffering and health care utilization in adults. Ample evidence suggests sociodemographic variables and socioeconomic status (SES) influence pain. However, a framework informing associations on race, SES, and the utilization of pharmacologic therapies and provider type are limite...
Article
Background: Racial disparities in trauma care have been reported for a range of outcomes, but the extent to which these remain after accounting for socioeconomic and environmental factors remains unclear. The objective of this study was to evaluate the unique contributions of race, health insurance, community distress, and rurality/urbanicity on t...
Article
Full-text available
Individuals with chronic low back pain (cLBP) frequently report sleep disturbances. Living in a neighborhood characterized by low-socioeconomic status (SES) is associated with a variety of negative health outcomes, including poor sleep. Whether low-neighborhood SES exacerbates sleep disturbances of people with cLBP, relative to pain-free individual...
Article
Dispositional traits can be protective or contribute to increased vulnerability in individuals with chronic pain. This study aims to evaluate the association between two dispositional trait measures, affect balance style and multi-domain trait groups, with psychosocial measures, clinical pain, functional pain, and experimental pain at two years in...
Article
Background and Purpose How the Area Deprivation Index (ADI) performs compared to other measures of socioeconomic status (SES) is unknown. The study purpose is to compare the ADI and other measures of SES in their ability to predict pain severity/interference. Methods Four measures of SES were compared—ADI, income, education, and subjective social...
Article
Full-text available
Compelling evidence exists that non-Hispanic blacks (NHB) engage in pain catastrophizing (negatively evaluate one’s ability to cope with pain) more often than non-Hispanic whites (NHW). Functional neuroimaging studies revealed that individuals with high levels of trait pain catastrophizing show increased cerebral responses to pain in several pain-r...
Article
Chronic pain is variably associated with brain structure. Phenotyping based on pain severity may address inconsistencies. Sociodemographic groups also differ in the experience of chronic pain severity. Whether differences by chronic pain severity and/or sociodemographic groups are indicated in pain-related areas of the brain is unknown. Relations b...
Article
Full-text available
Interpersonal violence (IPV) is highly prevalent in the United States and is a major public health problem. The emergence and/or worsening of chronic pain are known sequelae of IPV; however, not all those who experience IPV develop chronic pain. To mitigate its development, it is critical to identify the factors that are associated with increased r...
Article
Background: Cancer-related pain is highly prevalent and is commonly treated with prescription opioids. The Centers for Disease Control and Prevention (CDC) now encourages conservative opioid prescribing in recognition of potential opioid-related risks. However, CDC guidelines have been misapplied to patients with cancer. Recent laws at the state l...
Article
Millions of patients with cancer pain are treated with prescription opioids each year. However, efforts to mitigate the ongoing opioid crisis result in unintended consequences with opioid pain management, including opioid stigma. Emerging research indicates that opioid stigma is problematic in patients with cancer, but few studies have examined con...
Article
Full-text available
Background Biopsychosocial factors above and beyond pathoanatomical changes likely contribute to the severity of chronic low back pain. A pro-nociceptive endogenous pain modulatory balance (↓inhibition and ↑facilitation) may be an important contributor to chronic low back pain severity and physical function; however, additional research is needed t...
Article
Full-text available
Background: Pain is the hallmark symptom of knee osteoarthritis (OA), and varies widely across individuals. Previous research has demonstrated both fluctuating and stable pain trajectories in knee OA using various time periods. Changes in pain assessed quarterly (i.e. 3-month intervals) in knee OA are relatively unknown. The current study aimed to...
Article
Full-text available
Chronic low back pain (CLBP) is among the most prevalent musculoskeletal pain conditions, accounting for the largest number of years lived with disability. A growing literature suggests that low socioeconomic status (SES) is associated with diminished physical functioning and increased physical limitations, antecedents for disability. Emerging evid...
Article
Chronic pain is a common comorbidity in people with HIV (PWH), with prevalence estimates of 25-85%. Research in this area is growing, but significant gaps remain. A Global Task Force of HIV experts was organized to brainstorm a scientific agenda and identify measurement domains critical to advancing research in this field. Experts were identified t...
Article
Background: Non-Hispanic black (NHB) individuals have increased risk of Alzheimer's disease (AD) relative to non-Hispanic whites (NHW). Ethnicity/race can serve as a proxy sociodemographic variable for a complex representation of sociocultural and environmental factors. Chronic pain is a form of stress with high prevalence and sociodemographic dis...
Article
Chronic musculoskeletal (MSK) pain is disabling to individuals and burdensome to society. A relationship between telomere length and resilience was reported in individuals with consideration for chronic pain intensity. While chronic pain associates with brain changes, little is known regarding the neurobiological interface of resilience. In a group...
Article
Full-text available
Knee osteoarthritis (KOA) is a leading cause of mobility disability that is characterized by chronic pain among older adults. Non-Hispanic Blacks (NHBs) suffer disproportionately from non-Hispanic Whites (NHWs), reporting higher pain intensity and disability. It is unclear how these differences in symptomatology translate into different patterns of...
Article
Full-text available
PurposeTo determine the usefulness of cumulative and additive risk models in predicting the healthy-related quality of life (HRQOL) of caregivers of youth with chronic gastrointestinal conditions.Methods203 caregivers (82.8% mothers; 77.3% white) of youth (M = 11.27 years; 44.3% female; 78.8% White) completed self-report questionnaires focused on p...
Article
Full-text available
Chronic low back pain (cLBP) that cannot be attributable to a specific pathoanatomical change is associated with high personal and societal costs. Still, the underlying mechanism that causes and sustains such a phenotype is largely unknown. Emerging evidence suggests that epigenetic changes play a role in chronic pain conditions. Using reduced repr...
Article
Knee osteoarthritis (OA) is a leading cause of late life pain and disability, and non-Hispanic black (NHB) adults experience greater OA-related pain and disability than non-Hispanic whites (NHWs). Recent evidence implicates psychosocial stress, cognitive-attentional processes, and altered central pain processing as contributors to greater OA-relate...
Article
Full-text available
Background Patients with co-occurring chronic pain and opioid use disorder (OUD) have unique needs that may present challenges for clinicians and health care systems. Primary care providers’ (PCPs) capacity to deliver high quality, research-informed care for this population is unknown. The objective of this study was to develop and test a questionn...
Article
Pain intensity, pain interference, internalizing symptoms, and quality of life (HRQOL) were explored in three symptomatically similar gastrointestinal disorders: Recurrent Abdominal Pain, Eosinophilic Esophagitis, and Gastroesophageal Reflux Disease. Caregiver-proxy report was gathered for 133 pediatric patients at the time of endoscopy. There was...
Article
Objective Knee osteoarthritis (OA) is a leading source of pain and disability among older adults. Self‐management (SM) strategies are recommended to manage OA symptoms. Sociodemographic and clinical characteristics, along with other factors, may influence SM utilization rate. This study sought to examine the prevalence and correlates of SM use for...
Article
Full-text available
The prevalence of chronic widespread pain (CWP) in people with HIV is high, yet the underlying mechanisms are elusive. Leukocytes synthesize the endogenous opioid, β-endorphin, within their endoplasmic reticulum (ER). When released into plasma, β-endorphin dampens nociception by binding to opioid receptors on sensory neurons. We hypothesized that t...
Article
Full-text available
Evidence indicates that over half of all people with HIV (PWH) will experience nonmalignant chronic pain throughout their lifetimes, with increasing prevalence as they age. Peripheral neuropathy resulting from the neurotoxic effects of HIV itself and the medications used to treat HIV were widely considered the primary cause of acute and chronic pai...
Article
Background: Chronic low back pain (cLBP) is the leading cause of disability, with a significant societal cost. It disproportionately affects Non-Hispanic Blacks and individuals of lower socioeconomic status (SES). The biopsychosocial framework has been used to study and manage cLBP, yet disparities persist. Objectives: To assess whether self-ide...
Article
Full-text available
Purpose: Research indicates pain-related disparities in the impact of knee osteoarthritis (OA) across both sex and ethnicity/race. While several factors likely contribute to these disparities, experiences of discrimination are associated with poor OA-related pain, disability, and functional performance. However, the mechanisms that mediate experie...
Article
Objective: Chronological age is a risk factor in chronic pain; however, aging research supports the premise that physical and psychological health may better predict perceived age. Given the lack of evidence on perceived age in the context of chronic pain, the current study presents novel findings about the relationship between perceived age, chro...
Preprint
Full-text available
The prevalence of chronic widespread pain (CWP) in people with HIV (PWH) is high, yet the underlying mechanisms are elusive. Leukocytes synthesize the endogenous opioid, β-endorphin (β-END), within their endoplasmic reticulum (ER). When released into plasma, β-END dampens nociceptive transmission by binding to opioid receptors on sensory neurons. I...
Article
Full-text available
Objective: For most patients with chronic low back pain (cLBP), the cause is "nonspecific," meaning there is no clear association between pain and identifiable pathology of the spine or associated tissues. Laypersons and providers alike are less inclined to help, feel less sympathy, dislike patients more, suspect deception, and attribute lower pai...
Article
Full-text available
Background: Sex differences in pain sensitivity have been well documented, such that women often report greater sensitivity than men. However, clinical reports highlighting sex differences often equate gender and sex. This is a particularly critical oversight for those whose gender identity is different than their genetic sex. Methods: This prel...
Article
Full-text available
Objective: Patients with a combination of chronic pain and opioid use disorder have unique needs and may present a challenge for clinicians and health care systems. The objective of the present study was to use qualitative methods to explore factors influencing the uptake of best practices for co-occurring chronic pain and opioid use disorder in or...
Article
Full-text available
Pain catastrophizing is a cognitive-affective response during painful experiences and is implicated in the facilitation of pain processing. Non-Hispanic blacks (NHB) more often engage in catastrophizing as a coping strategy compared to non-Hispanic whites (NHW). Hence, pain catastrophizing may contribute to poorer pain-related outcomes and greater...
Article
Full-text available
Objectives: To determine the association between opioid prescribing rates and substantiated abuse and neglect across Tennessee counties during an 11-year period. Methods: We adopted a Bayesian spatiotemporal approach to determine the association between opioid prescribing and rates of substantiated child abuse and neglect over and above environm...
Article
Full-text available
Objective Chronic pain is increasingly recognized as a common and disabling problem for people living with HIV (PLWH). In a recent systematic review of psychosocial factors associated with chronic pain in PLWH, it was reported that very few studies to date have examined protective psychological factors that might help mitigate chronic pain for PLWH...