Bünyamin Şahin

Verified

Bünyamin verified their affiliation via an institutional email.

Learn more

Verified

Bünyamin verified their affiliation via an institutional email.

Learn more

• Ph.D. (Human Anatomy)
• Faculty Member at Ondokuz Mayıs University

Recent advancements in neuroimaging techniques have facilitated the identification of numerous structural brain alterations associated with schizophrenia, potentially serving as valuable biomarkers. This study aimed to explore the volumetric changes in the pineal gland correlated with schizophrenia symptoms, employing standard brain segmentation me...

KEY WORDS: Cobb angle, length squared, planimetry, radiography, scoliosis Objectives: Precise measurement of spinal curvature is the cornerstone for assessment of and intervention for spinal scoliosis. This study provides an alternative and reliable approach for spinal curvature measurement. Design: This retrospective study was authorized and condu...

Parkinson’s disease (PD) is a neurodegenerative disorder with an unexplored link to the cerebellum. In the pathophysiology of balance disorders in PD, the role of the flocculonodular lobe (FL) is linked to the impairment of the dopaminergic system. Dopamine deficiency can also lead to changes in cerebellum functions, disrupting balance control. Thi...

BACKGROUND: Dental arch measurements varied in different ethnic groups and populations, the dimensions continue changing in accordance with growth and development until the adulthood stage, these changes will decrease. The aim of this study is to measure the mandibular arch among Sudanese, using a new technique which is the PAL in MR images. METHOD...

Quantifying radiological images is important in dental research, providing insights into anatomical and pathological aspects. This study addresses these challenges by exploring various techniques used in our previous studies for quantifying dental radiological images. The projection area fraction (PAF) method, using digital planimetry and ImageJ, a...

https://usktubas.org/yuklemeler/21.USK%20ÖZET%20KİTABI.pdf

Objective: The exact volume of the bone cyst is fundamental for evaluation, treatment, and surgical management of the pathology related to any bone. The aim of this study was to introduce the stereological point-counting technique in bone cyst volume measurements on computed tomography images and to compare it with the planimetry technique. Methods...

The present study aimed to measure the cortical structures of cerebral hemispheres, including cortical thickness (CT), grey and white matter volume (GMV and WMV) and volume fraction (GMVF and WMVF), in addition to the volume (V) and cortical area pial (CAP) in normal young adult Sudanese and to investigate the effect of sex and age on these cortica...

Introduction In this study, the relation between carpal tunnel syndrome (CTS) severity and the carpal tunnel volume (CTV), volume and the volume fraction of the carpal tunnel contents on subjects with CTS and healthy individuals were examined. Material and Methods 30 female patients diagnosed with CTS clinically and electrophysiologically and 16 h...

Background: To date, there is no study has addressed the effect of race on cortical thickness (CT), cortical area pial (CAP), and the surface fraction of cortical area pial (SFCAP). The present study aimed to provide an overview about similarities and differences in CT, CAP, and SFCAP of the hemisphere, frontal lobe, and frontal lobe gyri between m...

Introduction: Clinical anatomy of the external ear canal (EEC) has a significant role in the diagnosis of Otitis Media (OM) and other auditory system diseases. OM is one of the most common infections and major causes of morbidity in adults if the complications of the OM take place. In the developing and low-income countries, the OM has a direct an...

Most investigations on Parkinson’s disease (PD) focus on the basal ganglia and brainstem, whereas the cerebellum has often been overlooked. The cerebellum is critical for motor control and increasing evidence suggests that it may be associated with the pathophysiology of PD. The aim of this study was to describe cerebral and cerebellar volumes in p...

The periocular region has a central role in the prediction of ethnicity, understanding emotional expression, age, and sex. The aim of this study was to determine the sex-related growth changes in the periocular region of Turkish preadolescents, adolescents, and young adults. The study included a total of 234 individuals (preadolescents: 34 females...

The nose has a tremendous effect on facial esthetics and overall facial harmony, accordingly it contributes to the physical appearance of individuals. The aim of this study is to establish sex-related nasal soft tissue norms for preadolescents, adolescents, and young adults in Anatolian population. A total of 300 volunteers (150 males and 150 femal...

Grey matter (GM) of the frontal lobe carries out its complex function such as muscle control, speech, decision making, and self-control; while the white matter (WM) of frontal lobe is a major contributor to human brain enlargement and higher structural connectivity. This study was conducted to assess the effect of sex and age on grey and white matt...

Complications encountered in the chronic phase in flail chest patients are a decrease in lung volume due to chest wall deformities and secondary restrictive respiratory function disorders. The aim of the study was to determine the differences in lung volume changes between flail chest patients who were treated non-surgically and those who were trea...

Introduction Morphometry of the external ear canal (EEC) clinically essential and can lead to solve diagnostic dilemma of many disease affect the auditory system, as Otitis media (OM). OM continues to be one of the most common childhood infections and is a major cause of morbidity in children and adults if the OM complications occurs. Although OM i...

In addition to the pelvis, cranium and phalanges, the sternum is also used for postmortem sex identification. Bone measurements may be obtained on cadaveric bones. Alternatively, computerized tomography may be used to obtain measurements close to the original ones. Moreover, usage of artificial neural networks (ANNs) in the field of medicine has st...

Purpose: To evaluate the volume of bone cyst using the planimetry method of the Cavalieri principle. Methods: A retrospective analysis was carried out on data from 25 computed tomography (CT) images of patients with bone cyst. The volume of the cysts was calculated by two independent observers using the planimetry method. The procedures were rep...

The rostral part of the nasal cavity is cooler to prevent the loss of water that is crucial for the fluid balance of birds. This function may be related to the structure of the nose of flying birds. For this reason, we decided to analyze the nasal structure of two different birds using volume and volume fraction approach of the stereology. In this...

Aim: This study investigates the total sternum length and the lengths of each part of the sternum using computed tomography (CT) images oriented orthogonally to reveal whether there are any significant gender differences with respect to these values. Material and Methods: Thin-section thorax CT images from 60 subjects (30F, 30M) between 20 and 40 y...

MR imaging studies in paediatric bipolar disorder have particularly focused on the amygdala and hippocampus, subcortical structures, and to a lesser extent on the thalamus. The purpose of this study was to perform structural analysis of the regions of interest (ROI) associated with mood regulation. In this study 18 children (between the ages of 12...

Objective The aim of this study was to evaluate, quantitatively, the volumetric effects of stabilization splint therapy on the masseter muscle of sleep bruxism (SB) patients. Methods The magnetic resonance (MR) images of 16 SB patients diagnosed by polysomnography (PSG) who used stabilization splints for four months were obtained before and after...

Purpose: The aim of this study was to determine the primary motor cortex volumetric measurements among the Sudanese healthy adult. Methods: 88 healthy Sudanese young adult were included in a survey for volumetric analysis of primary motor cortex. Magnetic resonance imaging and questionnaire were used to collect data for brain segmentation, personal...

Purpose: The aim of this study was to determine the primary motor cortex volumetric measurements among the Sudanese healthy adult. Methods: 88 healthy Sudanese young adult were included in a survey for volumetric analysis of primary motor cortex. Magnetic resonance imaging and questionnaire were used to collect data for brain segmentation, personal...

Purpose: the primary sensory cortex is the part of cerebral cortex which responsible for general somatocutaneous sensation. The aim of present study was to determine the volume of primary sensory cortex among the Sudanese healthy adult. Methods: 88 control subjects (51 male and 37 female) were participated in the study. The age of participants were...

Purpose Determination of the effect of tourniquet use in total knee arthroplasty (TKA) on thigh and quadriceps muscle volume using magnetic resonance imaging (MRI). Methods A total of 148 knees of 74 patients (mean age 66.5 ± 4.8 years; female/male, 62/12) with bilateral primary varus gonarthrosis underwent unilateral TKA with a tourniquet (Group A...

Parkinson’s disease (PD) is a chronic progressive neurodegenerative disorder, leads to resting tremor, stiffness, slowness and impaired balance. Most investigations on PD focused on the basal ganglia and brainstem, whereas the cerebellum has often been overlooked. Therefore, the aim of this study was determined to describe and compare the cerebral...

Grey and white matter volumes of the cerebral hemisphere are essential for connectivity and cognitive function of the brain, they varies with sex, age, and health status of subjects. The aim of the present study is to measure the grey and white matter volumes and volume fractions of the cerebral hemispheres to examine the sex differences in young h...

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, which occurs as a result of the compression of the median nerve in the carpal tunnel of the wrist. The aim of this study is to evaluate the MR images of the carpal tunnel and to show the volume and volume fraction of the carpal tunnel contents to the total carpal tunnel volume i...

Heart volume along with dose volume histograms are essential in reducing pulmonary and cardiac complications. The aim of this study is to measure the ventricular volume using computerized tomography (CT) and magnetic resonance imaging (MRI), to detect the differences between the two scans and to investigate whether the estimated volumes concur with...

Parkinson’s disease (PD) commonly begins in late middle age and the course is slowly progressive. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with PD. The aim of this study is to perform the measurements of the cerebral hemispheres and lateral ventricles using magnetic resonance imaging (MRI) in combination...

Parkinson’s disease (PD) is a slowly progressive neurological disorder that affects movement, muscle control, and balance. It develops as cells are destroyed in certain parts of the brain stem. The aim of this study is to measure the volume and volume fraction of the brainstem parts to examine the differences between affected regions in the PD. For...

The corpus callosum (CC) is the largest white-matter fibre tract in the brain that plays essential role in communicating sensory, motor and cognitive information between the two cerebral hemispheres. Corpus callosum area has been examined extensively in neurodegenerative diseases as a marker for cortical pathology and for differential diagnosis. Ho...

Objective Thalamic abnormalities have been reported in people with pervasive developmental disorders (PDD) including Asperger's Disorder (ASP). The aim of the present study was to compare the volume and volume fraction of the thalamus and the metabolite concentrations in children and adolescents with ASP using the magnetic resonance imaging and pro...

Parkinson's disease (PD) is associated with degeneration of the dopaminergic neurons in the substantia nigra. The subthalamic nucleus (STN) plays a pivotal role in the pathogenesis. However, there is not much known about the morphological changes in the STN. The red nucleus (RN) has many connections with the motor coordinating pathways although it...

Advances in neuroimaging have enabled studies of specific neuroanatomical abnormalities with relevance to schizophrenia. This study quantified structural alterations on brain magnetic resonance (MR) images of patients with schizophrenia. MR brain imaging was done on 88 control and 57 schizophrenic subjects and Dicom images were analyzed with ImageJ...

1. The conchae within the nasal cavity of poultry are important for water and energy conservation, but have not been experimentally evaluated. The aim of the present study was to determine the accuracy of volume and volume fraction estimates of the conchae, nasal septum and nasal cavity. 2. The nasal cavities of 7 adult goose heads were scanned usi...

Objectives: The aim of this study was to evaluate the lung volume changes depending on the resected lobes. The changes were quantitatively evaluated using stereological methods on computed tomography images and by pulmonary function tests (PFTs). Methods: The study subjects included 30 patients who underwent lung resection. Of these, 26 patients...

Objectives To assess the increase in lung volume after Nuss surgery in patients with pectus excavatum (PE) by using stereological methods and to evaluate the correlation between the lung volume and spirometry findings. Methods Twenty patients, treated for PE between 2008 and 2010, were evaluated prospectively. They underwent preoperative chest radi...

Although brain development is most active during the intrauterina period of life, the processes of myelination and arborization affect the structure of the brain throughout childhood and adolescence. Brain development is also very active in the early years of a child's life, and continues to be so for approximately 15 years after gestation. Volumet...

Cerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted un...

Objective: Endoscopic third ventriculostomy (ETV) is a procedure commonly applied in the treatment of non-communicating (obstructive) hydrocephalus. One of the rare complications that can occur following ETV is a subdural effusion, even though this procedure is considered to be a more controlled and natural method of cerebrospinal fluid drainage c...

Background: Studies evaluating the mean volumes of nasal cavity and concha are very rare. Since there is little date on the mentioned topic, we aimed to carry out the presented study to obtain a volumetric index showing the relation between the nasal cavity and concha. Material and methods: The volumes of the nasal cavity and concha were measure...

The purpose of this study was to investigate the possible effects of section thickness on volume estimations obtained by cone beam computed tomography. Intraosseal cavities representing bone defects on vestibular sides of the two dry sheep mandibles were scanned by a cone beam computed tomography system. Consecutive sections at 0.2, 0.6, 1, 1.4, an...

Intracranial volume (ICV) is an important data to evaluate the premorbid brain size in pathological conditions. It is also one of the most important characters for determining the racial difference. Several methods have been proposed for the assessment of ICV. Some of them are used only for the macerated skulls and most of them are suitable both fo...

The purpose of this study is to compare the computer-assisted planimetry and point-counting methods in evaluating the sizes of the mandibular cysts with respect to their agreement and the time required to analyze. The surface areas of 46 mandibular cyst lesions on orthopantomograms were estimated using the point-counting and computer-assisted plani...

There are several studies that have proposed different criteria for evaluating the volumes of the cerebral hemispheres, the lateral and third ventricles in patients with schizophrenia seen on routine computed tomography (CT) images. These approaches use solely the volume of the cerebrum and/or lateral ventricles, length and width measurements of th...

ARTICLE INFO ABSTRACT No previous study has yet reported the effects of surgical treatment of hydatid cysts on spleen volume. Our aim was to use computed tomography images to evaluate the vo-lume differences in the spleen in postoperative periods in patients who had undergone operations for hydatid cysts. The abdominal computed tomography scans of...

ARTICLE INFO ABSTRACT Measurement of brain volume is regarded as an objective marker of neurodegenerative diseases. The purpose of this study is to evaluate intra-rater variation for the estimation of volume of cerebral structures using the Cavalieri principle on magnetic resonance (MR) images to determine its reproducibility. The MR images of 30 c...

Objective: The aim of the study was to determine the volume of orbits and cranial cavity and to evaluate the relation between their volumes. Material and Methods: Twenty dry skulls of 10 men and 10 women were used for this study. Water filling method was used to measure the volumes of cranial cavity and orbits. The holes of the both cavities had be...

Size changes of the brain is monitorized for clinical or research purposes. Stereological methods provide some techniques to obtain quantitative information about the size of the brain or size relation of its components within the whole. The Cavalieri principle is the main technique to estimate the volume of brain and its components. Using this tec...

The Cavalieri principle of stereological methods is widely used to estimate the volume of structures. Recently in clinical practice, it has become common to use this approach for daily routine purposes. The Cavalieri principle provides quantitative and unbiased volume estimates which are independent of the observer. In the present study, the effica...

The aim of this study was to combine the stereological technique with magnetic resonance (MR) imaging data for the volumetric and functional analysis of the left ventricle (LV). Cardiac MR examinations were performed in 13 consecutive subjects with known or suspected coronary artery disease. The end-diastolic volume (EDV), end-systolic volume, ejec...

The objectives of this study were to investigate the lesion load on brain magnetic resonance images and the volume of different cerebral anatomical structures, in patients with a diagnosis of definite multiple sclerosis, using a stereological method. Fifty patients diagnosed with multiple sclerosis were included in the study. The volume fractions o...

In this study, we aimed to describe the application of the Cavalieri principle for the assessment of tumor volume using MRI without an over-projection/estimation effect. For this purpose, the volume of a patient's brain and the brain tumor volume, or the volume of the former tumor region, were estimated preoperatively and postoperatively using a co...

We aimed to evaluate the relevant methods of stereology to estimate hemicerebellar asymmetry according to sex in both adult right handed vertigo cases and comparing with healthy cases. The study included 14 adult control subjects and 18 patients with vertigo. The volumes of the cerebellar hemispheres were determined by MRI using the point-counting...

We aimed to evaluate the relevant methods of stereology to estimate hemicerebellar asymmetry according to sex in both adult right handed vertigo cases and comparing with healthy cases. The study included 14 adult control subjects and 18 patients with vertigo. The volumes of the cerebellar hemispheres were determined by MRI using the point-counting...

Although the injury to the peripheral nervous system is a common clinical problem, understanding of the role of melatonin in nerve degeneration and regeneration is incomplete. The current study investigated the effects of neonatal pinealectomy on the sciatic nerve microarchitecture in the chicken. The chickens were divided into two equal groups: un...

It is known that the kidney size is related to body height, body surface area and body weight. In the present study we propose the volume fraction approach of stereological methods that eliminate the effects of body size over the quantitative evaluation of cortex, medulla and pelvis of kidney. Kidneys were removed from 20 Kivircik sheeps and their...

To evaluate the efficacy of stereologic methods to measure the orbital volume using computed tomography images of patients with zygomatic fractures. The present study was retrospectively conducted using hard-copy computed tomography images acquired during the postoperative period of 22 patients with unilateral zygomatic fractures. Orbital volume me...

This study was carried out to describe a simple, accurate, and practical technique for assessing mandible cysts' area on routine orthopantomograms using digital planimetry.Forty orthopantomograms showing mandibular cysts were obtained. The digitalized images were used to measure the surface area of the half mandibles and cysts using ImageJ software...

Leiomyoma is a common benign tumor of the genital system; diseases and other types of smooth muscle tumors in females is called leiomyosarcoma. The diagnosis of these tumors is based on differentiation of the degree of cellularity and cytological atypia, presence of necrosis and particularly the mitotic index. A treatment procedure is proposed rega...

Although the effects of melatonin on vascular smooth muscle and vascular reactivity are described in last decade, the effects of melatonin on vascular tissues are still vague. The current study investigated the effects of pinealectomy on the blood vessel wall in the chicken. Fifteen chicks were divided into three groups, namely unoperated control,...

Several methodologies have been proposed to assess the orbital volume (OV). However, we have not seen a criterion standard study evaluating the results of the methodologies for the assessment of OV. In the current study, the actual OV of 9 dry skulls was measured using the water filling method as the criterion standard. Consecutive computed tomogra...

In this study, we describe and adapt the relevant methods of magnetic resonance (MR) and stereology to estimate total brain volume (TBV), cerebral and cerebellar volume and their volume fractions within the brain. The study included 15 (8 males, 7 females) controls and 15 (8 males, 7 females) patients with Alzheimer's disease. The patients’ MR imag...

Normal function of the peripheral nerve (PN) is based on morphological integrity and relationship between axons, Schwann cells, and connective sheaths, which depends on the correct development of all these components. Most of the relevant studies in this field were carried out using animal models, since reports on the development of the human PNs f...

The size of the eyeball has been the subject of a few studies. None of them used stereological methods to estimate the volume. In the current study, we estimated the volume of eyeball in normal men and women using the stereological methods. Eyeball volume (EV) was estimated using the Cavalieri principle as a combination of point-counting and planim...

Leiomyoma is a common benign tumor of the genital system; diseases and other types of smooth muscle tumors in females is called leiomyosarcoma. The diagnosis of these tumors is based on differentiation of the degree of cellularity and cytological atypia, presence of necrosis and particularly the mitotic index. A treatment procedure is proposed rega...

To demonstrate hemispheric asymmetry in patients with schizophrenia using a cheap, simple stereologic method on the basis of standard CT scans of the brain. To demonstrate hemispheric asymmetry, standard CT scans of 30 schizophrenic patients (14 males, 16 females) were compared with 39 (13 male, 26 female) control subjects at Eskisehir Osmangazi Un...

Age-related volumetric differences in brain anatomy or volumetric brain analyses in many disorders are of interest. Delineating the normal anatomical cerebellar volume is of importance for both the anatomists and clinicians. In the present study, we aimed to evaluate the cerebellar volume using a stereological technique and to determine the possibl...

Estimation of intracranial volume (ICV) using computed tomography (CT) scans has previously been described. However, we were not able to identify a gold standard study that analyzed the effect of section thickness on the estimation of ICV. Therefore, we conducted the present study, scanning five dry skulls in the coronal and axial planes using a mu...

The Cavalieri estimator using a point grid is used to estimate the volume of three-dimensional structures based on two-dimensional slices of the object. The size of the components of intracranial neural structures should have proportional relations among them. The volume fraction approach of stereological methods provides information about volumetr...

Several methods have been described to evaluate the degree of lumbar lordosis. However, suggested methods have used non-standardized terminology and landmarks to measure the degree of lumbar lordosis. In the present study a practical method for evaluating the degree of lumbar lordosis is described and, for this purpose, 24 lateral roentgenograms we...

The cerebellum is involved in motor learning and cognitive function in human. Many studies have been conducted to assess the cerebellar volume. To the best of our knowledge, there is no cerebellar volume study evaluating the efficiency and the accuracy of point-counting and planimetry methods of the Cavalieri principle in the literature. In this st...

The aim of the present study was to find the most efficient sampling strategy for stereological analysis of peripheral nerve, including the number of myelinated nerve fibres, axon cross-sectional area and myelin sheet thicknesses of nerve fibres. Two groups of rats underwent experimental resection of the tibial and peroneal nerves. The first group...

Diclofenac sodium (DS) is commonly used as a non-steroidal anti-inflammatory drug. Although several adverse effects are clearly established, it is still unknown whether prenatal exposure to DS has an effect on the development of the cerebellum. In this study, we investigated the total number of Purkinje cells of the cerebellum in a control group an...

Investigators can infer how much reduction in volume has occurred since brain volume was at its peak, by combining measures of brain volume with measures of intracranial volume (ICV). Several methodologies have been proposed to asses the ICV. However, we have not seen a gold-standard study evaluating the results of the methodologies for the assessm...

The size and shape of paranasal sinuses are especially relevant when considering endoscopic sinus surgery. For this reason, the size of the paranasal sinuses has been the subject of many studies, none of which has used stereological methods to estimate the volume. In the present stereological study, we estimated the volume of paranasal sinuses of n...

Following lung resection, the thoracic cavity may be filled partially or completely by the remaining pulmonary tissue. To our knowledge, no study has yet evaluated this volumetric change in thoracic content using high resolution computed tomography (HRCT) scans. We aimed to evaluate the volume changes of the lungs using HRCT scans during the preope...

Epidural hematoma (EH) is a serious clinical event observed in 2% of head trauma patients. Studies regarding the effects of epidural hematoma volume (EHV) on prognosis are not sufficient. In this study, we applied the volume fraction approach of the stereological method to estimate the hematoma to brain volume fraction (HBVF), and investigated the...

Purpose: Malignant pleural mesothelioma (MPM) is an extremely lethal neoplasm and continues to be an im-portant health problem in communities facing occupational or environmental exposure to asbestos. One of the most significant problems in the treatment of MPM is the lack of a standardized criterion for the evaluation of response to chemotherapy....

There is a well-known close relationship between the total intracranial volume (TIV) and the brain size. Several studies in different countries have estimated the cranial capacity, which indirectly reflects the brain volume. However, we have not seen a study evaluating the results of the methodologies for the assessment of TIV. This study was carri...

The accurate measurement of vitiligo surface area is fundamental to the evaluation of treatment efficacy. Digital photography, planimetry and clinical evaluation by the clinician have been used for assessment. Although digital photography with computerized planimetry is a reliable and accurate method, it is labour intensive and expensive. The aim o...

A better understanding of regenerative growth is very important for the development of new potential strategies. Recently, the pineal secretory product melatonin was shown to stimulate the regeneration process. In this study, we carried out an experimental investigation of tail regeneration in young adult lizards, Ophisops elegans macrodactylus Ber...