Brittany Mathes Winnicki

Hoarding disorder (HD) is a persistent and severe psychiatric condition in which individuals are unable to discard possessions, which results in considerable clutter. Individuals who hoard often endorse interpersonal difficulties and social isolation. However, little research has examined mechanisms that may help to explain this relationship. One p...

Hoarding disorder (HD) is a severe and persistent mental illness characterized by extreme difficulty parting with possessions and considerable clutter that can result in dangerous living conditions. HD poses a considerable public health burden; however, treatment for HD remains relatively limited, as many individuals do not respond to treatment and...

Background and objectives Hoarding disorder (HD) is a debilitating mental illness characterized by extreme difficulty parting with possessions and clutter that can result in dangerous living conditions. One hypothesis about why individuals with HD save possessions is that they possess a pathological attachment to their belongings, which may serve t...

Background Rumination, defined as perseverative thinking regarding the causes and consequences of psychological symptoms, is a risk and maintaining factor for PTSD. Existing work has largely focused on the extent to which rumination functions as a coping strategy used to avoid traumatic memories and associated emotions. However, rumination may also...

Social connection consists of both the presence of and perceived closeness in social relationships. Perceptions of connection are thought to be particularly important in the development and treatment of excessive alcohol use. However, no review has delineated existing work regarding the prospective associations between perceived social connection a...

Novel and automated means of opioid use and relapse risk detection are needed. Unstructured electronic medical record data, including written progress notes, can be mined for clinically relevant information, including the presence of substance use and relapse—critical markers of risk and recovery from opioid use disorder (OUD). In this study, we us...

Obsessive-compulsive disorder (OCD) affects ~1% of the population and exhibits a high SNP-heritability, yet previous genome-wide association studies (GWAS) have provided limited information on the genetic etiology and underlying biological mechanisms of the disorder. We conducted a GWAS meta-analysis combining 53,660 OCD cases and 2,044,417 control...

While exposure therapy is the most effective psychological treatment for obsessive-compulsive disorder (OCD), anxiety, and traumatic stress-related disorders, it is not universally effective, indicating a need for further treatment optimization. This study investigated a shift in approach to exposure therapy with 29 treatment-refractory adults in a...

Despite their brevity, prior work indicates that computer-based interventions can substantially impact risk factors for psychopathology including anxiety sensitivity (AS), thwarted belongingness (TB), and perceived burdensomeness (PB). However, very few studies have assessed the long-term (> 1 year) effects of these interventions. The primary aim o...

Hostility is a trait-level construct characterized by a generally suspicious and cynical view of other people that results in a tendency to interpret ambiguous social situations in hostile or threatening ways. Cognitive behavioral treatments for hostility have high dropout rates, which may be due to hostile beliefs interfering with treatment engage...

In addition to impacting the physical health of millions of Americans, the novel-coronavirus (COVID-19) pandemic is a significant psychological stressor due to both the threat of the illness itself and the mitigation strategies used to contain the spread. To facilitate understanding of the impact of COVID-19, validated measures are needed. Using a...

Overview Hoarding Disorder (HD) is characterized by extreme attachment to one's possessions. Despite a number of studies showing that this attachment may partially be driven by interpersonal dysfunction, few have identified specific factors underlying these interpersonal issues and object attachment (OA) within HD. To address this, we investigated...

Background Anxiety sensitivity (AS) is a well-studied transdiagnostic risk construct that is believed to amplify responses to many forms of stress. The COVID-19 pandemic is a broad stressor with significant physical and social threats. In the current study, we were interested in ascertaining the degree to which AS would relate to distress and disab...

Objectives: Despite the existence of several first-line treatments for obsessive-compulsive disorder (OCD), many patients fail to experience symptom reduction and/or do not complete treatment. As a result, the field has increasingly moved towards identifying and treating malleable underlying risk factors that may in turn improve treatment efficacy...

Background : Interpersonal trauma (IPT) is one of the most commonly reported types of traumatic experiences and has the greatest likelihood of resulting in a diagnosis of posttraumatic stress disorder (PTSD). Relative to other types of trauma, victims of IPT report greater trauma-specific rumination, whereby they focus on negative consequences of t...

Objective Accurate threat appraisal is central to survival. In the case of the coronavirus pandemic, accurate threat appraisal is difficult due to incomplete medical knowledge as well as complex social factors (e.g., mixed public health messages). The purpose of this study was to evaluate the degree to which individuals accurately perceive COVID-19...

The direct threat posed by the 2019 novel coronavirus (COVID-19), uncertainty surrounding best safety practices, and secondary consequences of the virus have led to widespread stress and declining mental health across communities and individuals. These stresses may impact parenting behaviors, potentially leading to negative consequences for childre...

Background Despite the high prevalence and burden of mental health disorders, the majority of affected individuals go untreated. Therefore, increased efforts have been made to develop and examine brief online interventions as a cost-effective, broadly disseminable alternative to traditional psychotherapy. In particular, recent studies have demonstr...

Few studies have examined indices of change in treatment for obsessive compulsive disorder (OCD). The current study evaluated within- and between-session trajectories of fear, disgust, and urge to wash in exposure and response prevention (ERP) for contamination-based OCD and tested whether change in these indices were associated with treatment outc...

There is a growing body of research aimed at identifying predictors of suicide risk among Veterans. One predictor may be hostility, as hostility and anger are associated with greater suicidal ideation among Veterans. The interpersonal theory of suicide suggests hostility may be associated with suicide risk through perceived burdensomeness and thwar...

Although sexual intrusive thoughts (SITs) are often studied in combination with other intrusions, little is known about the metacognitive processes that are specific to SITs. The present study evaluated sexual versus non-SIT frequency in relation to two main factors: gender and general negative beliefs (GNB), a component of metacognition involving...

Perfectionism is frequently noted in obsessive–compulsive disorder (OCD) and some data suggest that treatment outcomes with cognitive behavioral therapy (CBT) are poorer for OCD patients with higher levels of perfectionism. However, this literature includes inconsistent findings and has thus far been limited to outpatient samples. Existing studies...

Purpose of Review This review highlights recent research regarding gender differences in OCD, with a focus on prevalence, course of illness, symptom presentation, comorbidity, and treatment response. Recent Findings Overall, findings remain mixed. OCD may be more common among males in childhood, but is more common among females in adolescence and...

Perfectionism, a trait-like individual difference variable reflecting the tendency to set extremely high standards along with critical evaluations of one's own behavior, has long been regarded as a risk and maintenance factor for obsessive-compulsive disorder (OCD). However, research exploring the relationship between these constructs is mixed. One...

Objectives A prior study found that over 50% of treatment‐seeking individuals who hoard incur at least one psychiatric work impairment day (i.e., they are unable to work or are less effective at work due to poor mental health) each month. The aim of the current study was to assess work‐related variables associated with workplace impairment in a non...

Contamination fear and washing compulsions are among the most common symptoms of obsessive compulsive disorder (OCD). Though these symptoms have traditionally been viewed as being driven by a desire to avoid harm, recent research has highlighted the importance of feelings of incompleteness (INC) or not-just right experiences (NJREs) in this symptom...

Background: This study investigated distinct trajectories of treatment response in a naturalistic intensive/residential treatment (IRT) program for adults with severe obsessive-compulsive disorder (OCD). We hypothesized that: (1) distinct trajectories would emerge and (2) demographic variables, psychiatric comorbidity, OCD symptom subtype, level o...

“Not just right” experiences (NJREs) are uncomfortable sensations of incompleteness linked to obsessive–compulsive disorder; however, NJREs may be transdiagnostic and play a role in eating pathology. The current study examined relations between NJREs and eating pathology in undergraduate students. Participants (n = 248) completed self-report and be...

The most common symptom of obsessive compulsive disorder is contamination fear. Feelings of contamination can be provoked through contact with a physical contaminant, referred to as contact contamination (CC), as well as in the absence of one, referred to as mental contamination (MC). Prior research indicates that CC and MC are distinct, and MC may...

Posttraumatic stress disorder (PTSD) symptoms are positively related to suicide risk among firefighters. One mechanism that may account for this relationship is anxiety sensitivity (AS) cognitive concerns-the fear that cognitive symptoms of anxiety will have catastrophic consequences. We sought to replicate the mediating effect of AS cognitive conc...

Cyberchondria refers to a clinical phenomenon in which repeated Internet searches regarding medical information result in excessive concerns about physical health. Cyberchondria is positively associated with symptoms of health anxiety, though it remains unclear as to whether cyberchondria poses a unique public burden. The current study replicated p...

Background: A growing body of literature indicates that exposure to interpersonal trauma contributes to the onset or exacerbation of hoarding symptoms. However, little research has explored psychosocial factors that may help to explain the relationship between interpersonal trauma and hoarding symptoms. One outcome of trauma exposure that may be a...

Objective: This study aimed to develop and validate the Distress Tolerance Scale-Short Form (DTS-SF), a modification of the original Distress Tolerance Scale, in a severe/complex sample of individuals with obsessive compulsive disorder (OCD). Currently, there are multiple self-report measurements of distress tolerance (DT), highlighting the need f...

Obsessive-compulsive disorder (OCD) is a notably heterogeneous disorder. As such, there has been increased interest in subtyping OCD into homogeneous entities using biological characteristics such as sex. Whereas there is large consensus in the literature regarding sex differences in the phenotypic expression of OCD, there are numerous disadvantage...

Objective: Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explore whether willingness to exp...

Prior research has shown that difficulties in emotion regulation is associated with overall levels of posttraumatic stress symptoms (PTSS). However, it is currently unclear which facets of difficulties in emotion regulation (e.g., lack of emotion regulation strategies, impulse control problems, non-acceptance of emotional responses) are associated...

Background: Hoarding disorder (HD) is a common and debilitating disorder characterized by an accumulation of and failure to discard one's possessions. The identification and examination of underlying factors that may contribute to hoarding symptoms are needed to elucidate the nature of the disorder and refine existing treatments. Two transdiagnost...

Background: Intolerance of uncertainty (IU) has been associated with post-traumatic stress symptoms (PTSS) in the literature. However, no research to date has investigated the relationship between IU and PTSS within a clinical trauma-exposed sample, which is an important next step in the literature and crucial for the generalizability of these fin...

Introduction/Background: Individuals with OCD demonstrate impairments with aspects of behavioral inhibition, including difficulty enabling executive control over pre-potent motor responses in accordance with changing situational demands. Chamberlain and colleagues (2005) suggested that OCD symptoms might be best characterized in terms of failures t...

Insomnia symptoms are associated with smoking and may interfere with smoking cessation. Specifically, studies have shown that smoking-related sleep problems are associated with long-term smoking relapse, and longer sleep duration is associated with successful smoking cessation. However, it is currently unclear whether pre- or post-quit insomnia sym...

Eating disorders and obsessive-compulsive disorder (OCD) co-occur at rates as high as 41% (Kaye, Bulik, Thornton, Barbarich, & Masters, 2014), but little is known about how this comorbidity may affect treatment outcome. Imaging evidence across EDs and OCD reveals a common dysfunction of self-regulatory processes. Impaired orbitofrontal cortex (OFC)...

• Obsessive compulsive disorder (OCD) is characterized by intrusive, distressing thoughts (i.e., obsessions), as well as repetitive behaviors aimed to reduce distress (i.e., compulsions; APA, 2013). • Response inhibition (RI) is a neuropsychological construct that refers to one’s ability to inhibit a pre-potent motor response. • RI may contribute t...

Obsessive-compulsive disorder (OCD) can take many forms, limited only by the imagination of the human mind. Advances in research surrounding OCD have established that efficacious treatments, such as exposure and response prevention (ERP), do exist. Even though ERP should provide the foundation for OCD treatment, ERP can be perceived as a highly ave...

The Stages of Change model conceptualizes the process of behavioral change. The University of Rhode Island Change Assessment (URICA) is a self-report measure divided into subscales that represent four of the five different stages (Precontemplation, Contemplation, Action, and Maintenance). Research has shown that higher Precontemplation scores predi...

Background: Intensive residential treatment (IRT) is effective for severe, treatment-resistant obsessive-compulsive disorder (OCD). We sought to characterize predictors and course of response to IRT. Methods: Admission, monthly, and discharge data were collected on individuals receiving IRT. We examined the association between baseline character...